ZA979328B - Process for the preparation of n-[2-(dimethylamino)ethyl[acridine-4-carboxamide - Google Patents

Process for the preparation of n-[2-(dimethylamino)ethyl[acridine-4-carboxamide

Info

Publication number
ZA979328B
ZA979328B ZA979328A ZA979328A ZA979328B ZA 979328 B ZA979328 B ZA 979328B ZA 979328 A ZA979328 A ZA 979328A ZA 979328 A ZA979328 A ZA 979328A ZA 979328 B ZA979328 B ZA 979328B
Authority
ZA
South Africa
Prior art keywords
pct
alkyl
different
same
sec
Prior art date
Application number
ZA979328A
Other languages
English (en)
Inventor
William Alexander Denny
Swarnalatha Akuratiya Gamage
Julie Ann Spicer
Michael Wright
David Frank Hayman
Original Assignee
Xenova Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenova Ltd filed Critical Xenova Ltd
Publication of ZA979328B publication Critical patent/ZA979328B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polishing Bodies And Polishing Tools (AREA)
  • Multicomponent Fibers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Liquid Crystal (AREA)
ZA979328A 1996-10-18 1997-10-17 Process for the preparation of n-[2-(dimethylamino)ethyl[acridine-4-carboxamide ZA979328B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9621795.5A GB9621795D0 (en) 1996-10-18 1996-10-18 Pharmaceutical compounds

Publications (1)

Publication Number Publication Date
ZA979328B true ZA979328B (en) 1998-07-06

Family

ID=10801674

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA979328A ZA979328B (en) 1996-10-18 1997-10-17 Process for the preparation of n-[2-(dimethylamino)ethyl[acridine-4-carboxamide
ZA9709331A ZA979331B (en) 1996-10-18 1997-10-17 Pharmaceutical compounds.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA9709331A ZA979331B (en) 1996-10-18 1997-10-17 Pharmaceutical compounds.

Country Status (30)

Country Link
US (1) US6114332A (da)
EP (1) EP0934278B1 (da)
JP (1) JP2001503399A (da)
KR (1) KR20000049252A (da)
CN (1) CN1116285C (da)
AT (1) ATE223381T1 (da)
AU (1) AU717724B2 (da)
BG (1) BG64555B1 (da)
BR (1) BR9711948A (da)
CA (1) CA2268411C (da)
CZ (1) CZ295302B6 (da)
DE (1) DE69715230T2 (da)
DK (1) DK0934278T3 (da)
ES (1) ES2183142T3 (da)
GB (2) GB9621795D0 (da)
HK (1) HK1018773A1 (da)
HU (1) HU221953B1 (da)
ID (1) ID22444A (da)
MY (1) MY122017A (da)
NO (1) NO313381B1 (da)
NZ (1) NZ335055A (da)
PL (1) PL193669B1 (da)
PT (1) PT934278E (da)
RO (1) RO120636B1 (da)
RU (1) RU2179972C2 (da)
SK (1) SK285121B6 (da)
TW (1) TW432060B (da)
UA (1) UA67729C2 (da)
WO (1) WO1998017650A1 (da)
ZA (2) ZA979328B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6974878B2 (en) 2001-03-21 2005-12-13 Symyx Technologies, Inc. Catalyst ligands, catalytic metal complexes and processes using same
EP1131283A1 (en) * 1999-09-10 2001-09-12 Symyx Technologies Catalyst ligands, catalytic metal complexes and processes using and methods of making same
WO2005063760A1 (en) * 2003-12-31 2005-07-14 Council Of Scientific & Industrial Research C-8 LINKED PYRROLO[2,1-c][1,4]BENZODIAZEPINE-ACRIDONE/ACRIDINE HYBRIDS
EP3086791A4 (en) * 2013-12-24 2017-06-14 University of Florida Research Foundation, Inc. Phenazine derivatives as antimicrobial agents
CN104961801B (zh) * 2015-07-13 2018-01-19 兰州大学 一种具有多靶点的抗菌多肽偶联物及其二聚物的合成和应用
CN106554321B (zh) * 2015-09-25 2019-05-28 陆源 一种吩嗪类物质、其制备方法及其应用
US20240279204A1 (en) * 2021-12-09 2024-08-22 Korea Institute Of Ocean Science & Technology Novel diphenazine compound, and use thereof for preventing or treating cancer or neuroinflammatory diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201084A (en) * 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
JPS61112061A (ja) * 1984-08-16 1986-05-30 デベロツプメント フアイナンス コ−ポレ−シヨン オブニユ−ジ−ランド 新規なフエナジン誘導体
IT1293525B1 (it) * 1997-08-01 1999-03-01 Uni Degli Studi Camerino Bis-acridincarbossiammidi aventi attivita' antitumorale

Also Published As

Publication number Publication date
AU717724B2 (en) 2000-03-30
BG103329A (en) 2000-11-30
GB9621795D0 (en) 1996-12-11
JP2001503399A (ja) 2001-03-13
EP0934278B1 (en) 2002-09-04
GB2334032B (en) 2000-11-08
US6114332A (en) 2000-09-05
TW432060B (en) 2001-05-01
GB9908192D0 (en) 1999-06-02
CZ127199A3 (cs) 1999-09-15
SK285121B6 (sk) 2006-06-01
NZ335055A (en) 2000-09-29
CZ295302B6 (cs) 2005-07-13
DK0934278T3 (da) 2003-01-06
NO991833L (no) 1999-06-03
NO991833D0 (no) 1999-04-16
ES2183142T3 (es) 2003-03-16
BG64555B1 (bg) 2005-07-29
ATE223381T1 (de) 2002-09-15
BR9711948A (pt) 1999-08-24
DE69715230D1 (de) 2002-10-10
DE69715230T2 (de) 2009-09-17
CN1116285C (zh) 2003-07-30
PL193669B1 (pl) 2007-03-30
UA67729C2 (uk) 2004-07-15
RU2179972C2 (ru) 2002-02-27
KR20000049252A (ko) 2000-07-25
ZA979331B (en) 1998-05-21
CN1240430A (zh) 2000-01-05
HU221953B1 (hu) 2003-03-28
WO1998017650A1 (en) 1998-04-30
AU4713797A (en) 1998-05-15
NO313381B1 (no) 2002-09-23
RO120636B1 (ro) 2006-05-30
GB2334032A (en) 1999-08-11
PL332877A1 (en) 1999-10-25
CA2268411A1 (en) 1998-04-30
SK50499A3 (en) 2000-05-16
EP0934278A1 (en) 1999-08-11
PT934278E (pt) 2003-01-31
ID22444A (id) 1999-10-14
MY122017A (en) 2006-03-31
HK1018773A1 (en) 2000-01-07
HUP9902883A3 (en) 2001-01-29
CA2268411C (en) 2008-07-22

Similar Documents

Publication Publication Date Title
MY114679A (en) Aroyl-piperidine derivatives
HUP0301514A2 (hu) Benzimidazol származékok, elżállításuk és ezeket tartalmazó gyógyszerkészítmények
MY129540A (en) Quinazoline derivatives, pharmaceutical compositions containing them processes for their preparation and their use in the production of an antiangiogenic and/or vascular permeability reducing effect
EP0353955A3 (en) Novel compounds
ES8503666A1 (es) Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas
DE69019859D1 (de) Chinolon-Derivate und deren Salze, Verfahren zu deren Herstellung und diese enthaltende antibakterielle Wirkstoffe.
ES8802014A1 (es) Un procedimiento para la preparacion de derivados de ariletanolamina.
ZA979328B (en) Process for the preparation of n-[2-(dimethylamino)ethyl[acridine-4-carboxamide
HUP0203275A2 (hu) 1-(Gyűrűs amino)-alkilciklohexán-származékok, ezeket tartalmazó görcsoldó hatású gyógyszerkészítmények, valamint ezek alkalmazása
DE68926981D1 (de) Cephemverbindungen und Verfahren zu ihrer Herstellung
ATE173727T1 (de) Substituierte chinoline für die behandlung von leismaniosen
HUP0003861A2 (hu) Kinolin-4-il-származékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyászati készítmények
RU99109978A (ru) Бис(акридинкарбоксамид) и бис(феназинкарбоксамид), полезные в качестве противоопухолевых агентов
GR3023373T3 (en) Novel carbocyclic nucleoside agents useful as selective inhibitors of proinflammatory cytokines
IL115085A0 (en) Bicyclic carboxamide derivatives their preparation and pharmaceutical compositions containing them
TW338036B (en) Novel phenylethyl and phenylpropylamines, their preparation process and pharmaceutical compositions containing them
ES8504713A1 (es) Un procedimiento para preparar nuevas dihidropiridinas
MY104048A (en) New allylaminoethylazoles.
DE69225381D1 (de) Nootrope Wirkstoffe
TH18165A (th) สารยับยั้งการเกิดคีโมแทกซิของอีโอซีโนฟีล
RU94012551A (ru) Бензамидные производные, способы их получения, фармацевтическая композиция и способ лечения