ES8504713A1 - Un procedimiento para preparar nuevas dihidropiridinas - Google Patents
Un procedimiento para preparar nuevas dihidropiridinasInfo
- Publication number
- ES8504713A1 ES8504713A1 ES535216A ES535216A ES8504713A1 ES 8504713 A1 ES8504713 A1 ES 8504713A1 ES 535216 A ES535216 A ES 535216A ES 535216 A ES535216 A ES 535216A ES 8504713 A1 ES8504713 A1 ES 8504713A1
- Authority
- ES
- Spain
- Prior art keywords
- straight
- compounds
- carbon atoms
- group
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR NUEVAS DEHIDROPIRIDINAS.CONSISTE EN HACER REACCIONAR A UN COMPUESTO DE FORMULA (II), EN PRESENCIA DE UN CATALIZADOR RANEY COMO NI RANEY O CO RANEY, EN UN DISOLVENTE COMO METANOL, BENCENO, ACETONA Y OTROS, Y A UNA TEMPERATURA ENTRE 15J Y 100JC, PARA OBTENER UN COMPUESTO DE FORMULA (I), SUS SALES FISIOLOGICAMENTE ACEPTABLES Y SUS ISOMEROS OPTICOS; R, UNO O DOS SUSTITUYENTES (IGUALES O DIFERENTES) EN EL ANILLO DE FENILO, SELECCIONADOS ENTRE NO2, CN, CF3 Y OTROS; R2, -S-B-NRR; R Y R UN GRUPO ALCOHILO RECTO O RAMIFICADO DE C 1 A 5; R, UN GRUPO ALCOHILO RECTO O RAMIFICADO DE C 1 A 5, CON SU CADENA INTERRUMPIDA POR O2; R UN GRUPO ALCOHILO INFERIOR; Y A Y B UN GRUPO ALCOHILENO RECTO O RAMIFICADO DE C 2 A 5.SE UTILIZAN COMO ANTIHIPERTENSIVOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8203176 | 1982-05-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES535216A0 ES535216A0 (es) | 1985-05-01 |
| ES8504713A1 true ES8504713A1 (es) | 1985-05-01 |
Family
ID=20346867
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES522570A Expired ES8503655A1 (es) | 1982-05-21 | 1983-05-20 | Un procedimiento para preparar nuevas dihidropiridinas. |
| ES535216A Expired ES8504713A1 (es) | 1982-05-21 | 1984-08-16 | Un procedimiento para preparar nuevas dihidropiridinas |
| ES535215A Expired ES8504712A1 (es) | 1982-05-21 | 1984-08-16 | Un procedimiento para preparar nuevas dihidropiridinas |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES522570A Expired ES8503655A1 (es) | 1982-05-21 | 1983-05-20 | Un procedimiento para preparar nuevas dihidropiridinas. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES535215A Expired ES8504712A1 (es) | 1982-05-21 | 1984-08-16 | Un procedimiento para preparar nuevas dihidropiridinas |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0095451A3 (es) |
| JP (1) | JPS58210063A (es) |
| KR (1) | KR900006682B1 (es) |
| AU (1) | AU1464583A (es) |
| CA (1) | CA1205471A (es) |
| DD (2) | DD216009A5 (es) |
| DK (1) | DK223683A (es) |
| ES (3) | ES8503655A1 (es) |
| FI (1) | FI80677C (es) |
| GB (1) | GB2120668B (es) |
| GR (1) | GR78566B (es) |
| HU (2) | HU193786B (es) |
| IL (1) | IL68524A0 (es) |
| IS (1) | IS1381B6 (es) |
| MW (1) | MW1783A1 (es) |
| NO (1) | NO163327C (es) |
| NZ (1) | NZ204283A (es) |
| PT (1) | PT76733B (es) |
| ZA (1) | ZA833112B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3600594A1 (de) * | 1986-01-11 | 1987-07-16 | Bayer Ag | Methioninsubstituierte 1,4-dihydropyridine, verfahren zur herstellung und ihre verwendung |
| US4814455A (en) * | 1986-04-16 | 1989-03-21 | Bristol-Myers Company | Dihydro-3,5-dicarboxylates |
| JPS63112560A (ja) * | 1986-10-29 | 1988-05-17 | Green Cross Corp:The | ジヒドロピリジン誘導体 |
| US5310917A (en) * | 1991-09-13 | 1994-05-10 | Merck & Co., Inc. | Process for the preparation of 4-substituted-1,4-dihydropydrines |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2747513A1 (de) * | 1977-10-22 | 1979-05-03 | Bayer Ag | Dihydropyridine mit schwefelhaltigen estergruppierungen |
| DE2861974D1 (en) * | 1977-11-11 | 1982-09-16 | Ciba Geigy Ag | Pyridine dicarboxylic acid derivatives, their mixtures with metallic stabilisers and their use in stabilising chlorine-containing thermoplasts |
| US4285955A (en) * | 1978-10-31 | 1981-08-25 | Bayer Aktiengesellschaft | 1,4-Dihydropyridinecarboxylic acids |
-
1983
- 1983-04-29 IL IL68524A patent/IL68524A0/xx unknown
- 1983-05-02 ZA ZA833112A patent/ZA833112B/xx unknown
- 1983-05-03 CA CA000427276A patent/CA1205471A/en not_active Expired
- 1983-05-06 MW MW17/83A patent/MW1783A1/xx unknown
- 1983-05-13 EP EP83850127A patent/EP0095451A3/en not_active Withdrawn
- 1983-05-18 NZ NZ204283A patent/NZ204283A/en unknown
- 1983-05-18 AU AU14645/83A patent/AU1464583A/en not_active Abandoned
- 1983-05-19 GR GR71397A patent/GR78566B/el unknown
- 1983-05-19 DK DK223683A patent/DK223683A/da not_active Application Discontinuation
- 1983-05-19 FI FI831778A patent/FI80677C/fi not_active IP Right Cessation
- 1983-05-20 DD DD83264588A patent/DD216009A5/de not_active IP Right Cessation
- 1983-05-20 ES ES522570A patent/ES8503655A1/es not_active Expired
- 1983-05-20 HU HU852491A patent/HU193786B/hu unknown
- 1983-05-20 JP JP58087768A patent/JPS58210063A/ja active Pending
- 1983-05-20 PT PT76733A patent/PT76733B/pt not_active IP Right Cessation
- 1983-05-20 IS IS2809A patent/IS1381B6/is unknown
- 1983-05-20 DD DD25113583A patent/DD209816A5/de unknown
- 1983-05-20 GB GB08314034A patent/GB2120668B/en not_active Expired
- 1983-05-20 NO NO831806A patent/NO163327C/no unknown
- 1983-05-20 HU HU831792A patent/HU188342B/hu not_active IP Right Cessation
- 1983-05-21 KR KR1019830002237A patent/KR900006682B1/ko not_active IP Right Cessation
-
1984
- 1984-08-16 ES ES535216A patent/ES8504713A1/es not_active Expired
- 1984-08-16 ES ES535215A patent/ES8504712A1/es not_active Expired
Also Published As
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| TH2763B (th) | ไดไฮโดรพิริดีนชนิดใหม่ | |
| TH1531A (th) | ไดไฮโดรพิริดีนชนิดใหม่ |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19991007 |