BG64555B1 - Бис(акридинкарбоксамид) и бис(феназинкарбоксамид) като антитуморни агенти - Google Patents
Бис(акридинкарбоксамид) и бис(феназинкарбоксамид) като антитуморни агенти Download PDFInfo
- Publication number
- BG64555B1 BG64555B1 BG103329A BG10332999A BG64555B1 BG 64555 B1 BG64555 B1 BG 64555B1 BG 103329 A BG103329 A BG 103329A BG 10332999 A BG10332999 A BG 10332999A BG 64555 B1 BG64555 B1 BG 64555B1
- Authority
- BG
- Bulgaria
- Prior art keywords
- arh
- bis
- nmr
- compound
- nch
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Polishing Bodies And Polishing Tools (AREA)
- Multicomponent Fibers (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Liquid Crystal (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9621795.5A GB9621795D0 (en) | 1996-10-18 | 1996-10-18 | Pharmaceutical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
BG103329A BG103329A (en) | 2000-11-30 |
BG64555B1 true BG64555B1 (bg) | 2005-07-29 |
Family
ID=10801674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG103329A BG64555B1 (bg) | 1996-10-18 | 1999-04-13 | Бис(акридинкарбоксамид) и бис(феназинкарбоксамид) като антитуморни агенти |
Country Status (30)
Country | Link |
---|---|
US (1) | US6114332A (da) |
EP (1) | EP0934278B1 (da) |
JP (1) | JP2001503399A (da) |
KR (1) | KR20000049252A (da) |
CN (1) | CN1116285C (da) |
AT (1) | ATE223381T1 (da) |
AU (1) | AU717724B2 (da) |
BG (1) | BG64555B1 (da) |
BR (1) | BR9711948A (da) |
CA (1) | CA2268411C (da) |
CZ (1) | CZ295302B6 (da) |
DE (1) | DE69715230T2 (da) |
DK (1) | DK0934278T3 (da) |
ES (1) | ES2183142T3 (da) |
GB (2) | GB9621795D0 (da) |
HK (1) | HK1018773A1 (da) |
HU (1) | HU221953B1 (da) |
ID (1) | ID22444A (da) |
MY (1) | MY122017A (da) |
NO (1) | NO313381B1 (da) |
NZ (1) | NZ335055A (da) |
PL (1) | PL193669B1 (da) |
PT (1) | PT934278E (da) |
RO (1) | RO120636B1 (da) |
RU (1) | RU2179972C2 (da) |
SK (1) | SK285121B6 (da) |
TW (1) | TW432060B (da) |
UA (1) | UA67729C2 (da) |
WO (1) | WO1998017650A1 (da) |
ZA (2) | ZA979328B (da) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6974878B2 (en) | 2001-03-21 | 2005-12-13 | Symyx Technologies, Inc. | Catalyst ligands, catalytic metal complexes and processes using same |
EP1131283A1 (en) * | 1999-09-10 | 2001-09-12 | Symyx Technologies | Catalyst ligands, catalytic metal complexes and processes using and methods of making same |
WO2005063760A1 (en) * | 2003-12-31 | 2005-07-14 | Council Of Scientific & Industrial Research | C-8 LINKED PYRROLO[2,1-c][1,4]BENZODIAZEPINE-ACRIDONE/ACRIDINE HYBRIDS |
EP3086791A4 (en) * | 2013-12-24 | 2017-06-14 | University of Florida Research Foundation, Inc. | Phenazine derivatives as antimicrobial agents |
CN104961801B (zh) * | 2015-07-13 | 2018-01-19 | 兰州大学 | 一种具有多靶点的抗菌多肽偶联物及其二聚物的合成和应用 |
CN106554321B (zh) * | 2015-09-25 | 2019-05-28 | 陆源 | 一种吩嗪类物质、其制备方法及其应用 |
US20240279204A1 (en) * | 2021-12-09 | 2024-08-22 | Korea Institute Of Ocean Science & Technology | Novel diphenazine compound, and use thereof for preventing or treating cancer or neuroinflammatory diseases |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ201084A (en) * | 1982-06-25 | 1985-10-11 | New Zealand Dev Finance | 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such |
JPS61112061A (ja) * | 1984-08-16 | 1986-05-30 | デベロツプメント フアイナンス コ−ポレ−シヨン オブニユ−ジ−ランド | 新規なフエナジン誘導体 |
IT1293525B1 (it) * | 1997-08-01 | 1999-03-01 | Uni Degli Studi Camerino | Bis-acridincarbossiammidi aventi attivita' antitumorale |
-
1996
- 1996-10-18 GB GBGB9621795.5A patent/GB9621795D0/en active Pending
-
1997
- 1997-10-17 HU HU9902883A patent/HU221953B1/hu not_active IP Right Cessation
- 1997-10-17 JP JP51910998A patent/JP2001503399A/ja not_active Ceased
- 1997-10-17 SK SK504-99A patent/SK285121B6/sk unknown
- 1997-10-17 KR KR1019990703357A patent/KR20000049252A/ko not_active Application Discontinuation
- 1997-10-17 EP EP97909456A patent/EP0934278B1/en not_active Expired - Lifetime
- 1997-10-17 DE DE69715230T patent/DE69715230T2/de not_active Expired - Fee Related
- 1997-10-17 NZ NZ335055A patent/NZ335055A/xx unknown
- 1997-10-17 US US09/284,623 patent/US6114332A/en not_active Expired - Fee Related
- 1997-10-17 GB GB9908192A patent/GB2334032B/en not_active Expired - Lifetime
- 1997-10-17 UA UA99042117A patent/UA67729C2/uk unknown
- 1997-10-17 WO PCT/GB1997/002886 patent/WO1998017650A1/en active IP Right Grant
- 1997-10-17 AT AT97909456T patent/ATE223381T1/de not_active IP Right Cessation
- 1997-10-17 BR BR9711948A patent/BR9711948A/pt not_active Application Discontinuation
- 1997-10-17 PL PL97332877A patent/PL193669B1/pl not_active IP Right Cessation
- 1997-10-17 ID IDW990196A patent/ID22444A/id unknown
- 1997-10-17 CZ CZ19991271A patent/CZ295302B6/cs not_active IP Right Cessation
- 1997-10-17 ZA ZA979328A patent/ZA979328B/xx unknown
- 1997-10-17 CA CA002268411A patent/CA2268411C/en not_active Expired - Fee Related
- 1997-10-17 RO RO99-00433A patent/RO120636B1/ro unknown
- 1997-10-17 MY MYPI97004914A patent/MY122017A/en unknown
- 1997-10-17 ZA ZA9709331A patent/ZA979331B/xx unknown
- 1997-10-17 CN CN97180614A patent/CN1116285C/zh not_active Expired - Fee Related
- 1997-10-17 RU RU99109978/04A patent/RU2179972C2/ru not_active IP Right Cessation
- 1997-10-17 AU AU47137/97A patent/AU717724B2/en not_active Ceased
- 1997-10-17 PT PT97909456T patent/PT934278E/pt unknown
- 1997-10-17 DK DK97909456T patent/DK0934278T3/da active
- 1997-10-17 ES ES97909456T patent/ES2183142T3/es not_active Expired - Lifetime
- 1997-10-18 TW TW086115404A patent/TW432060B/zh not_active IP Right Cessation
-
1999
- 1999-04-13 BG BG103329A patent/BG64555B1/bg unknown
- 1999-04-16 NO NO19991833A patent/NO313381B1/no not_active IP Right Cessation
- 1999-08-26 HK HK99103666A patent/HK1018773A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3719924A1 (de) | 8-substituierte 2-aminotetraline | |
King et al. | 297. The synthesis of benziminazoles from ortho-phenylenediamines and imino-ethers | |
BG64555B1 (bg) | Бис(акридинкарбоксамид) и бис(феназинкарбоксамид) като антитуморни агенти | |
Chen et al. | Electron-deficient DNA intercalating agents as antitumor drugs: Aza analogs of the experimental clinical agent N-[2-(dimethylamino) ethyl] acridine-4-carboxamide | |
JPH11508280A (ja) | 三環式アミノアルキルカルボキサミド;新規なドーパミンd▲下3▼受容体サブタイプに特異的なリガンド | |
CA2196370A1 (en) | Isoprene derivatives | |
DE69505362T2 (de) | Biphenyl-derivate als 5ht1d antagonisten | |
Price et al. | A Synthesis of Substituted 4-Aminoquinolines1 | |
RU2282615C2 (ru) | Способ получения индан-1,3-дикарбоновой кислоты | |
EP0934277B1 (en) | Process for the preparation of n- 2-(dimethylamino)ethyl]acridine-4-carboxamide | |
EP0187509A2 (en) | 9-Aminoalkylfluorenes | |
KR102078528B1 (ko) | 신규한 hdac6 억제제를 이용한 치매 또는 인지장애 예방 또는 치료용 약학적 조성물 | |
JPH0564955B2 (da) | ||
EP1360167A1 (en) | Symmetrically disubstituted aromatic compounds and pharmaceutical compositions for inhibiting poly (adp-ribose) glycohydrolase, and methods for their use | |
CN102260187B (zh) | 取代的氨甲酰基环己甲酸类化合物及其制法和用途 | |
WO2016019588A1 (en) | Oxacazone compounds to treat clostridium difficile | |
US3903165A (en) | Ethynylaryl amines and processes for their preparation | |
HU194175B (en) | Process for preparing n-phenyl-pyridine-amino-derivatives | |
GB1591120A (en) | Derivatives of a-amino benzimidazole-5-propanoic acid their preparation and compositions containing them | |
CN112521298A (zh) | 一种利多卡因的合成方法 | |
BE824158A (fr) | Procede de preparation de d(-)-alpha - aminobenzylpe nicillines | |
AU2001249957A1 (en) | Symmetrically disubstituted aromatic compounds and pharmaceutical compositions for inhibiting poly (ADP-Ribose) glycohydrolase, and methods for their use | |
JPS6281383A (ja) | 五環式化合物 |