SK284925B6 - Kombinovaný preparát a jeho použitie pri liečení neurodegeneratívnych ochorení - Google Patents
Kombinovaný preparát a jeho použitie pri liečení neurodegeneratívnych ochorení Download PDFInfo
- Publication number
- SK284925B6 SK284925B6 SK240-98A SK24098A SK284925B6 SK 284925 B6 SK284925 B6 SK 284925B6 SK 24098 A SK24098 A SK 24098A SK 284925 B6 SK284925 B6 SK 284925B6
- Authority
- SK
- Slovakia
- Prior art keywords
- adenosine
- ach
- concentration
- intracellular
- muscarinic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19707655A DE19707655A1 (de) | 1997-02-26 | 1997-02-26 | Kombinationspräparat zur Anwendung bei Demenz |
Publications (2)
Publication Number | Publication Date |
---|---|
SK24098A3 SK24098A3 (en) | 1998-09-09 |
SK284925B6 true SK284925B6 (sk) | 2006-02-02 |
Family
ID=7821517
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK240-98A SK284925B6 (sk) | 1997-02-26 | 1998-02-24 | Kombinovaný preparát a jeho použitie pri liečení neurodegeneratívnych ochorení |
Country Status (30)
Country | Link |
---|---|
US (1) | US6037347A (pl) |
EP (1) | EP0867192B1 (pl) |
JP (1) | JP4374440B2 (pl) |
KR (1) | KR100517186B1 (pl) |
CN (1) | CN100363005C (pl) |
AR (1) | AR011860A1 (pl) |
AT (1) | ATE295738T1 (pl) |
AU (1) | AU749278C (pl) |
BR (1) | BR9800766A (pl) |
CA (1) | CA2230350C (pl) |
CZ (1) | CZ298367B6 (pl) |
DE (2) | DE19707655A1 (pl) |
DK (1) | DK0867192T3 (pl) |
EE (1) | EE03387B1 (pl) |
ES (1) | ES2242243T3 (pl) |
HR (1) | HRP980097B1 (pl) |
HU (1) | HUP9800396A3 (pl) |
ID (1) | ID19941A (pl) |
IL (1) | IL123453A (pl) |
MY (1) | MY120530A (pl) |
NO (1) | NO327200B1 (pl) |
NZ (1) | NZ329839A (pl) |
PL (1) | PL191576B1 (pl) |
PT (1) | PT867192E (pl) |
RU (1) | RU2194508C2 (pl) |
SI (1) | SI0867192T1 (pl) |
SK (1) | SK284925B6 (pl) |
TR (1) | TR199800302A3 (pl) |
TW (1) | TW590772B (pl) |
ZA (1) | ZA981561B (pl) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ510683A (en) * | 1998-10-01 | 2003-09-26 | Novartis Ag | Sustained release oral formulations of rivastigmine |
US20040110776A1 (en) * | 2002-02-22 | 2004-06-10 | Iok-Hou Pang | Use of propentofylline to control intraocular pressure |
US20040092427A1 (en) * | 2002-09-25 | 2004-05-13 | Anil Gulati | Method and composition for treating alzheimer's disease and dementias of vascular origin |
US20090208579A1 (en) * | 2004-12-27 | 2009-08-20 | Eisai R & D Management Co., Ltd. | Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same |
US20060280789A1 (en) * | 2004-12-27 | 2006-12-14 | Eisai Research Institute | Sustained release formulations |
US20070129402A1 (en) * | 2004-12-27 | 2007-06-07 | Eisai Research Institute | Sustained release formulations |
US8481565B2 (en) | 2004-12-27 | 2013-07-09 | Eisai R&D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
KR101213345B1 (ko) * | 2005-04-28 | 2012-12-17 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 항치매약을 함유하는 조성물 |
WO2017044693A1 (en) | 2015-09-11 | 2017-03-16 | Chase Pharmaceuticals Corporation | Muscarinic combination and its use for combating hypocholinergic disorders of the central nervous system |
RU2616247C1 (ru) * | 2016-03-28 | 2017-04-13 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Северо-Осетинский государственный университет имени Коста Левановича Хетагурова" (СОГУ) | Твердая лекарственная форма, обладающая холинопозитивным действием, на основе 9-бутиламино-3,3-диметил-1,2,4-тригидроакридина |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3737433A (en) * | 1964-09-05 | 1973-06-05 | Albert Ag Chem Werke | Certain oxoalkyldimethylxanthines |
US3621096A (en) * | 1969-04-03 | 1971-11-16 | Univ North Carolina | Antidepressant method and composition for same comprising a tricyclic antidepressant and a thyroid hormone |
DE2330742C2 (de) * | 1973-06-16 | 1982-07-29 | Hoechst Ag, 6000 Frankfurt | 1-(Oxoalkyl)-3-methyl-7-alkylxanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
DE2856393C2 (de) * | 1978-12-27 | 1983-04-28 | Merz + Co GmbH & Co, 6000 Frankfurt | Arzneimittel zur Behandlung von Morbus Parkinson |
JPH062675B2 (ja) * | 1985-04-05 | 1994-01-12 | ヘキストジヤパン株式会社 | 記憶障害治療剤 |
DE3525801A1 (de) * | 1985-07-19 | 1987-01-22 | Hoechst Ag | Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung |
IL81610A (en) * | 1986-02-27 | 1990-12-23 | Roussel Uclaf | Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them |
GB8621870D0 (en) * | 1986-09-11 | 1986-10-15 | Beecham Group Plc | Active compounds |
FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
MX13270A (es) * | 1987-10-05 | 1993-06-01 | Pfizer | Procedimiento para la preparacion de derivados de 4-aminopiridina |
IL87861A0 (en) * | 1987-10-05 | 1989-03-31 | Pfizer | 4-aminopyridine derivatives |
DE3817955A1 (de) * | 1988-05-27 | 1989-11-30 | Hoechst Ag | Tnf-inhibitor enthaltendes arzneimittel |
JPH05506842A (ja) * | 1989-09-15 | 1993-10-07 | ジェンシア・ファーマシュウティカルズ・インコーポレイテッド | 神経変性状態の処置方法 |
DE4236331A1 (de) * | 1992-10-28 | 1994-05-05 | Boehringer Ingelheim Kg | Synergistische Kombination |
US5783584A (en) * | 1995-12-11 | 1998-07-21 | Mayo Foundation For Medical Education And Research | THA analogs useful as cholinesterase inhibitors |
GB9612710D0 (en) * | 1996-06-18 | 1996-08-21 | Pfizer Ltd | Method of treatment |
-
1997
- 1997-02-26 DE DE19707655A patent/DE19707655A1/de not_active Withdrawn
-
1998
- 1998-02-16 ID IDP980209A patent/ID19941A/id unknown
- 1998-02-16 ES ES98102620T patent/ES2242243T3/es not_active Expired - Lifetime
- 1998-02-16 DK DK98102620T patent/DK0867192T3/da active
- 1998-02-16 SI SI9830775T patent/SI0867192T1/xx unknown
- 1998-02-16 DE DE59812801T patent/DE59812801D1/de not_active Expired - Lifetime
- 1998-02-16 AT AT98102620T patent/ATE295738T1/de not_active IP Right Cessation
- 1998-02-16 PT PT98102620T patent/PT867192E/pt unknown
- 1998-02-16 EP EP98102620A patent/EP0867192B1/de not_active Expired - Lifetime
- 1998-02-23 EE EE9800075A patent/EE03387B1/xx not_active IP Right Cessation
- 1998-02-24 TR TR1998/00302A patent/TR199800302A3/tr unknown
- 1998-02-24 RU RU98103712/14A patent/RU2194508C2/ru not_active IP Right Cessation
- 1998-02-24 AU AU56273/98A patent/AU749278C/en not_active Ceased
- 1998-02-24 CA CA002230350A patent/CA2230350C/en not_active Expired - Fee Related
- 1998-02-24 NZ NZ329839A patent/NZ329839A/xx unknown
- 1998-02-24 SK SK240-98A patent/SK284925B6/sk not_active IP Right Cessation
- 1998-02-24 AR ARP980100810A patent/AR011860A1/es not_active Application Discontinuation
- 1998-02-24 TW TW087102577A patent/TW590772B/zh not_active IP Right Cessation
- 1998-02-24 CZ CZ0054098A patent/CZ298367B6/cs not_active IP Right Cessation
- 1998-02-25 CN CNB981053289A patent/CN100363005C/zh not_active Expired - Fee Related
- 1998-02-25 ZA ZA981561A patent/ZA981561B/xx unknown
- 1998-02-25 US US09/030,207 patent/US6037347A/en not_active Expired - Lifetime
- 1998-02-25 HU HU9800396A patent/HUP9800396A3/hu unknown
- 1998-02-25 IL IL12345398A patent/IL123453A/en not_active IP Right Cessation
- 1998-02-25 BR BR9800766-1A patent/BR9800766A/pt not_active Application Discontinuation
- 1998-02-25 JP JP04305898A patent/JP4374440B2/ja not_active Expired - Fee Related
- 1998-02-25 MY MYPI98000834A patent/MY120530A/en unknown
- 1998-02-25 HR HR980097A patent/HRP980097B1/xx not_active IP Right Cessation
- 1998-02-25 NO NO19980786A patent/NO327200B1/no not_active IP Right Cessation
- 1998-02-26 KR KR10-1998-0006051A patent/KR100517186B1/ko not_active IP Right Cessation
- 1998-02-26 PL PL325074A patent/PL191576B1/pl not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20100224 |