SK283369B6 - Mutantná fosfoenolpyruvátkarboxyláza, mikroorganizmus, rekombinantná DNA a spôsob výroby aminokyseliny - Google Patents

Mutantná fosfoenolpyruvátkarboxyláza, mikroorganizmus, rekombinantná DNA a spôsob výroby aminokyseliny Download PDF

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Publication number
SK283369B6
SK283369B6 SK204-96A SK20496A SK283369B6 SK 283369 B6 SK283369 B6 SK 283369B6 SK 20496 A SK20496 A SK 20496A SK 283369 B6 SK283369 B6 SK 283369B6
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SK
Slovakia
Prior art keywords
leu
phosphoenolpyruvate carboxylase
ala
glu
mutant
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SK204-96A
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English (en)
Slovak (sk)
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SK20496A3 (en
Inventor
Masakazu Sugimoto
Tomoko Suzuki
Hiroshi Hiroshi Matsui
Katsura Izui
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Ajinomoto Co., Inc.
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Application filed by Ajinomoto Co., Inc. filed Critical Ajinomoto Co., Inc.
Publication of SK20496A3 publication Critical patent/SK20496A3/sk
Publication of SK283369B6 publication Critical patent/SK283369B6/sk

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/14Glutamic acid; Glutamine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/20Aspartic acid; Asparagine

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SK204-96A 1993-08-24 1994-08-17 Mutantná fosfoenolpyruvátkarboxyláza, mikroorganizmus, rekombinantná DNA a spôsob výroby aminokyseliny SK283369B6 (sk)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP20977693 1993-08-24
JP20977593 1993-08-24
JP15387694 1994-07-05
PCT/JP1994/001365 WO1995006114A1 (en) 1993-08-24 1994-08-17 Variant phosphoenolpyruvate carboxylase, gene thereof, and process for producing amino acid

Publications (2)

Publication Number Publication Date
SK20496A3 SK20496A3 (en) 1996-11-06
SK283369B6 true SK283369B6 (sk) 2003-06-03

Family

ID=27320552

Family Applications (1)

Application Number Title Priority Date Filing Date
SK204-96A SK283369B6 (sk) 1993-08-24 1994-08-17 Mutantná fosfoenolpyruvátkarboxyláza, mikroorganizmus, rekombinantná DNA a spôsob výroby aminokyseliny

Country Status (15)

Country Link
US (2) US5876983A (cs)
EP (1) EP0723011B1 (cs)
KR (2) KR100337959B1 (cs)
CN (1) CN1179043C (cs)
AT (1) ATE220099T1 (cs)
AU (1) AU682547B2 (cs)
BR (1) BR9407625A (cs)
CA (1) CA2169170C (cs)
CZ (1) CZ289051B6 (cs)
DE (1) DE69430919T2 (cs)
HU (1) HU219600B (cs)
MY (1) MY112250A (cs)
PL (1) PL181380B1 (cs)
SK (1) SK283369B6 (cs)
WO (1) WO1995006114A1 (cs)

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US20030087381A1 (en) * 1998-04-13 2003-05-08 University Of Georgia Research Foundation, Inc. Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals
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US6927046B1 (en) * 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
KR100704517B1 (ko) 2000-01-21 2007-04-10 아지노모토 가부시키가이샤 L-라이신의 제조 방법 및 당해 방법에 사용된 미생물
KR100397423B1 (ko) * 2001-02-13 2003-09-13 씨제이 주식회사 L-쓰레오닌의 제조방법
US7368266B2 (en) 2001-02-13 2008-05-06 Cj Corporation Method for L-threonine production
US20030115638A1 (en) * 2001-08-17 2003-06-19 Ajinomoto Co., Inc. Plants having increased amino acids content and methods for producing the same
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KR100498971B1 (ko) * 2003-04-04 2005-07-04 씨제이 주식회사 염색체 내 tdcBC 및 pckA 유전자가 불활성화된 미생물 및 이를 이용하여 L-쓰레오닌을 제조하는 방법
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CN116113699B (zh) * 2020-12-24 2025-02-28 武汉远大弘元股份有限公司 改造的磷酸烯醇丙酮酸羧化酶及其在提高谷氨酸棒杆菌氨基酸产量中的应用
CN115678878A (zh) * 2021-07-28 2023-02-03 梅花(上海)生物科技有限公司 一种磷酸烯醇式丙酮酸羧化酶突变体及其应用
CN115806962A (zh) * 2021-09-15 2023-03-17 中国科学院天津工业生物技术研究所 磷酸烯醇式丙酮酸羧化酶突变体及其应用
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JPH07108228B2 (ja) * 1990-10-15 1995-11-22 味の素株式会社 温度感受性プラスミド

Also Published As

Publication number Publication date
PL313119A1 (en) 1996-06-10
BR9407625A (pt) 1997-01-21
ATE220099T1 (de) 2002-07-15
AU682547B2 (en) 1997-10-09
CZ52496A3 (en) 1996-06-12
WO1995006114A1 (en) 1995-03-02
PL181380B1 (pl) 2001-07-31
DE69430919D1 (de) 2002-08-08
MY112250A (en) 2001-05-31
EP0723011B1 (en) 2002-07-03
DE69430919T2 (de) 2003-02-27
CA2169170C (en) 2007-01-09
US5876983A (en) 1999-03-02
CZ289051B6 (cs) 2001-10-17
HU9600240D0 (en) 1996-03-28
HU219600B (hu) 2001-05-28
CN1179043C (zh) 2004-12-08
KR960704029A (ko) 1996-08-31
CN1133615A (zh) 1996-10-16
SK20496A3 (en) 1996-11-06
EP0723011A1 (en) 1996-07-24
US5919694A (en) 1999-07-06
EP0723011A4 (en) 1996-05-21
AU8099194A (en) 1995-03-21
CA2169170A1 (en) 1995-03-02
KR100337959B1 (ko) 2002-11-23
HUT73690A (en) 1996-09-30

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