ATE220099T1 - Eine phosphoenolpyruvat-carboxylasevariante, ihr gen und verfahren zur herstellung von aminosäuren - Google Patents

Eine phosphoenolpyruvat-carboxylasevariante, ihr gen und verfahren zur herstellung von aminosäuren

Info

Publication number
ATE220099T1
ATE220099T1 AT94924384T AT94924384T ATE220099T1 AT E220099 T1 ATE220099 T1 AT E220099T1 AT 94924384 T AT94924384 T AT 94924384T AT 94924384 T AT94924384 T AT 94924384T AT E220099 T1 ATE220099 T1 AT E220099T1
Authority
AT
Austria
Prior art keywords
gene
phosphoenolpyruvate carboxylase
amino acids
producing amino
carboxylase
Prior art date
Application number
AT94924384T
Other languages
English (en)
Inventor
Masakazu Ajinomoto Co Sugimoto
Kawasaki-Ku Suzuki-Cho
Tomoko Ajinomoto Co Inc Suzuki
Hiroshi Ajinomoto Co In Matsui
Katsura Izui
Original Assignee
Ajinomoto Kk
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Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27320552&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE220099(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of ATE220099T1 publication Critical patent/ATE220099T1/de

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/08Lysine; Diaminopimelic acid; Threonine; Valine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/14Glutamic acid; Glutamine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/20Aspartic acid; Asparagine

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT94924384T 1993-08-24 1994-08-17 Eine phosphoenolpyruvat-carboxylasevariante, ihr gen und verfahren zur herstellung von aminosäuren ATE220099T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP20977593 1993-08-24
JP20977693 1993-08-24
JP15387694 1994-07-05
PCT/JP1994/001365 WO1995006114A1 (fr) 1993-08-24 1994-08-17 Allele de phosphenolpyruvate carboxylase, gene de cet allele et procede de production de l'acide amine

Publications (1)

Publication Number Publication Date
ATE220099T1 true ATE220099T1 (de) 2002-07-15

Family

ID=27320552

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94924384T ATE220099T1 (de) 1993-08-24 1994-08-17 Eine phosphoenolpyruvat-carboxylasevariante, ihr gen und verfahren zur herstellung von aminosäuren

Country Status (15)

Country Link
US (2) US5876983A (de)
EP (1) EP0723011B1 (de)
KR (2) KR100337959B1 (de)
CN (1) CN1179043C (de)
AT (1) ATE220099T1 (de)
AU (1) AU682547B2 (de)
BR (1) BR9407625A (de)
CA (1) CA2169170C (de)
CZ (1) CZ289051B6 (de)
DE (1) DE69430919T2 (de)
HU (1) HU219600B (de)
MY (1) MY112250A (de)
PL (1) PL181380B1 (de)
SK (1) SK283369B6 (de)
WO (1) WO1995006114A1 (de)

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AU760575C (en) 1998-04-13 2005-04-14 University Of Georgia Research Foundation, Inc., The Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
WO2000039305A1 (en) * 1998-12-23 2000-07-06 Massachusetts Institute Of Technology PYRUVATE CARBOXYLASE FROM $i(CORYNEBACTERIUM GLUTAMICUM)
US6171833B1 (en) 1998-12-23 2001-01-09 Massachusetts Institute Of Technology Pyruvate carboxylase from corynebacterium glutamicum
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US6599732B1 (en) 1999-06-29 2003-07-29 Archer-Daniels-Midland Company Regulation of carbon assimilation
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US6727411B2 (en) 1999-12-13 2004-04-27 Ajinomoto Co., Inc. Method of producing transgenic plants having improved amino acid composition
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US6927046B1 (en) * 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
US7723081B1 (en) 2000-01-21 2010-05-25 Ajinomoto Co., Inc. Bacteria containing aspartate-semialdehyde dehydrogenase, phosphoenolpyruvate carboxylase, and transhydrogenase to produce L-lysine in escherichia, and methods of using same
US7368266B2 (en) 2001-02-13 2008-05-06 Cj Corporation Method for L-threonine production
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KR100498971B1 (ko) * 2003-04-04 2005-07-04 씨제이 주식회사 염색체 내 tdcBC 및 pckA 유전자가 불활성화된 미생물 및 이를 이용하여 L-쓰레오닌을 제조하는 방법
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BRPI0806695A2 (pt) * 2007-01-12 2014-06-03 Univ Colorado Composições e métodos para aumentar a tolerância à produção de produtos químicos produzidos por microorganismos
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US8883453B2 (en) * 2007-04-30 2014-11-11 University Of Maryland Codon specific mutagenesis
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BRPI0906795A2 (pt) 2008-01-23 2015-08-18 Ajinomoto Kk Método para produzir um l-aminoácido
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CN105132388B (zh) * 2015-09-06 2018-02-23 江南大学 一种酶活性提高的丙酮酸羧化酶突变体r485p及其应用
CN105907730B (zh) * 2016-05-11 2019-06-21 江南大学 一种酶活性提高的丙酮酸羧化酶突变体n1078f及其应用
CN110494566A (zh) 2017-02-02 2019-11-22 嘉吉公司 产生c6-c10脂肪酸衍生物的经遗传修饰的细胞
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CN116113699A (zh) * 2020-12-24 2023-05-12 武汉远大弘元股份有限公司 改造的磷酸烯醇丙酮酸羧化酶及其在提高谷氨酸棒杆菌氨基酸产量中的应用
CN115806962A (zh) * 2021-09-15 2023-03-17 中国科学院天津工业生物技术研究所 磷酸烯醇式丙酮酸羧化酶突变体及其应用

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JPH07108228B2 (ja) * 1990-10-15 1995-11-22 味の素株式会社 温度感受性プラスミド

Also Published As

Publication number Publication date
MY112250A (en) 2001-05-31
KR100337959B1 (ko) 2002-11-23
CA2169170C (en) 2007-01-09
EP0723011B1 (de) 2002-07-03
CZ52496A3 (en) 1996-06-12
EP0723011A4 (de) 1996-05-21
DE69430919D1 (de) 2002-08-08
HUT73690A (en) 1996-09-30
PL181380B1 (pl) 2001-07-31
HU9600240D0 (en) 1996-03-28
EP0723011A1 (de) 1996-07-24
AU8099194A (en) 1995-03-21
CA2169170A1 (en) 1995-03-02
SK20496A3 (en) 1996-11-06
WO1995006114A1 (fr) 1995-03-02
AU682547B2 (en) 1997-10-09
DE69430919T2 (de) 2003-02-27
KR960704029A (ko) 1996-08-31
US5919694A (en) 1999-07-06
US5876983A (en) 1999-03-02
BR9407625A (pt) 1997-01-21
PL313119A1 (en) 1996-06-10
SK283369B6 (sk) 2003-06-03
CN1179043C (zh) 2004-12-08
HU219600B (hu) 2001-05-28
CN1133615A (zh) 1996-10-16
CZ289051B6 (cs) 2001-10-17

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