SK283331B6 - 1-Fenylalkyl-1,2,3,6-tetrahydropyridíny, spôsob ich prípravy a farmaceutický prípravok - Google Patents

1-Fenylalkyl-1,2,3,6-tetrahydropyridíny, spôsob ich prípravy a farmaceutický prípravok Download PDF

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Publication number
SK283331B6
SK283331B6 SK786-99A SK78699A SK283331B6 SK 283331 B6 SK283331 B6 SK 283331B6 SK 78699 A SK78699 A SK 78699A SK 283331 B6 SK283331 B6 SK 283331B6
Authority
SK
Slovakia
Prior art keywords
carbon atoms
alkyl
group
alkoxy
ethyl
Prior art date
Application number
SK786-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK78699A3 (en
Inventor
Marco Baroni
Rosanna Cardamone
Jacqueline Fournier
Umberto Guzzi
Original Assignee
Sanofi-Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo filed Critical Sanofi-Synthelabo
Publication of SK78699A3 publication Critical patent/SK78699A3/sk
Publication of SK283331B6 publication Critical patent/SK283331B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
SK786-99A 1996-12-13 1997-12-12 1-Fenylalkyl-1,2,3,6-tetrahydropyridíny, spôsob ich prípravy a farmaceutický prípravok SK283331B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9615335A FR2757160B1 (fr) 1996-12-13 1996-12-13 1-phenylalkyl-1,2,3,6-tetrahydropyridines
PCT/FR1997/002286 WO1998025903A1 (fr) 1996-12-13 1997-12-12 1-phenylalkyl-1,2,3,6-tetrahydropyridines pour le traitement de la maladie d'alzheimer

Publications (2)

Publication Number Publication Date
SK78699A3 SK78699A3 (en) 2000-01-18
SK283331B6 true SK283331B6 (sk) 2003-06-03

Family

ID=9498641

Family Applications (1)

Application Number Title Priority Date Filing Date
SK786-99A SK283331B6 (sk) 1996-12-13 1997-12-12 1-Fenylalkyl-1,2,3,6-tetrahydropyridíny, spôsob ich prípravy a farmaceutický prípravok

Country Status (32)

Country Link
US (1) US6034090A (ko)
EP (1) EP0950048B1 (ko)
JP (1) JP3881384B2 (ko)
KR (1) KR100560358B1 (ko)
CN (1) CN1129579C (ko)
AT (1) ATE202561T1 (ko)
AU (1) AU730143B2 (ko)
BR (1) BR9713916A (ko)
CA (1) CA2275353C (ko)
CY (1) CY2274B1 (ko)
CZ (1) CZ289789B6 (ko)
DE (1) DE69705429T2 (ko)
DK (1) DK0950048T3 (ko)
EE (1) EE03763B1 (ko)
ES (1) ES2160977T3 (ko)
FR (1) FR2757160B1 (ko)
GR (1) GR3036643T3 (ko)
HK (1) HK1023997A1 (ko)
HU (1) HU224347B1 (ko)
IL (1) IL130003A (ko)
IS (1) IS1969B (ko)
NO (1) NO312720B1 (ko)
NZ (1) NZ336033A (ko)
PL (1) PL190789B1 (ko)
PT (1) PT950048E (ko)
RS (1) RS49807B (ko)
RU (1) RU2189975C2 (ko)
SI (1) SI0950048T1 (ko)
SK (1) SK283331B6 (ko)
TR (1) TR199901291T2 (ko)
UA (1) UA52707C2 (ko)
WO (1) WO1998025903A1 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2763847B1 (fr) * 1997-05-28 2003-06-06 Sanofi Sa Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
UA81749C2 (uk) * 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
FR2832405B1 (fr) * 2001-11-19 2004-12-10 Sanofi Synthelabo Tetrahydropyridyl-alkyl-heterocycles azotes, procede pour leur preparation et compositions pharmaceutiques les contenant

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1321701A (en) * 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same
IE34545B1 (en) * 1969-10-01 1975-06-11 Continental Pharma Amino-alcohols,their salts and process for preparing the same
FR2650505B1 (fr) * 1989-08-07 1994-06-03 Midy Spa Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
HU211019B (en) * 1991-12-02 1995-09-28 Richter Gedeon Vegyeszet Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds

Also Published As

Publication number Publication date
JP3881384B2 (ja) 2007-02-14
BR9713916A (pt) 2000-02-29
DE69705429D1 (de) 2001-08-02
PT950048E (pt) 2001-12-28
NO992869L (no) 1999-06-11
AU730143B2 (en) 2001-03-01
DK0950048T3 (da) 2001-09-24
NO992869D0 (no) 1999-06-11
HU224347B1 (hu) 2005-08-29
TR199901291T2 (xx) 1999-10-21
IL130003A (en) 2004-09-27
HUP0001185A3 (en) 2002-10-28
CZ211399A3 (cs) 2000-09-13
KR100560358B1 (ko) 2006-03-14
IL130003A0 (en) 2000-02-29
CA2275353C (en) 2007-05-22
CY2274B1 (en) 2003-07-04
CN1129579C (zh) 2003-12-03
EE9900237A (et) 1999-12-15
HUP0001185A2 (hu) 2000-10-28
CZ289789B6 (cs) 2002-04-17
ES2160977T3 (es) 2001-11-16
WO1998025903A1 (fr) 1998-06-18
RU2189975C2 (ru) 2002-09-27
JP2001505902A (ja) 2001-05-08
US6034090A (en) 2000-03-07
YU24399A (sh) 2001-07-10
FR2757160A1 (fr) 1998-06-19
CA2275353A1 (en) 1998-06-18
IS1969B (is) 2004-12-15
NZ336033A (en) 2000-12-22
EP0950048A1 (fr) 1999-10-20
CN1240427A (zh) 2000-01-05
KR20000069422A (ko) 2000-11-25
EE03763B1 (et) 2002-06-17
UA52707C2 (uk) 2003-01-15
RS49807B (sr) 2008-08-07
GR3036643T3 (en) 2001-12-31
NO312720B1 (no) 2002-06-24
PL190789B1 (pl) 2006-01-31
AU5489398A (en) 1998-07-03
SK78699A3 (en) 2000-01-18
IS5075A (is) 1999-06-10
FR2757160B1 (fr) 1999-03-12
DE69705429T2 (de) 2002-05-16
PL334071A1 (en) 2000-01-31
ATE202561T1 (de) 2001-07-15
SI0950048T1 (en) 2001-10-31
EP0950048B1 (fr) 2001-06-27
HK1023997A1 (en) 2000-09-29

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