SK282159B6 - Vodný roztok risperidónu a spôsob jeho prípravy - Google Patents

Vodný roztok risperidónu a spôsob jeho prípravy Download PDF

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Publication number
SK282159B6
SK282159B6 SK22-97A SK2297A SK282159B6 SK 282159 B6 SK282159 B6 SK 282159B6 SK 2297 A SK2297 A SK 2297A SK 282159 B6 SK282159 B6 SK 282159B6
Authority
SK
Slovakia
Prior art keywords
risperidone
water
aqueous solution
solution
solution according
Prior art date
Application number
SK22-97A
Other languages
English (en)
Slovak (sk)
Other versions
SK2297A3 (en
Inventor
Marc Karel Jozef Francois
Willy Maria Albert Carlo Dries
Original Assignee
Janssen Pharmaceutica N. V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26955530&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK282159(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica N. V. filed Critical Janssen Pharmaceutica N. V.
Publication of SK2297A3 publication Critical patent/SK2297A3/sk
Publication of SK282159B6 publication Critical patent/SK282159B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK22-97A 1994-07-11 1995-07-04 Vodný roztok risperidónu a spôsob jeho prípravy SK282159B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/272,462 US5453425A (en) 1994-07-11 1994-07-11 Risperidone oral formulation
US08/429,435 US5616587A (en) 1994-07-11 1995-04-26 Aqueous risperidone formulations
PCT/EP1995/002615 WO1996001652A1 (fr) 1994-07-11 1995-07-04 Formulations aqueuses de risperidone

Publications (2)

Publication Number Publication Date
SK2297A3 SK2297A3 (en) 1997-09-10
SK282159B6 true SK282159B6 (sk) 2001-11-06

Family

ID=26955530

Family Applications (1)

Application Number Title Priority Date Filing Date
SK22-97A SK282159B6 (sk) 1994-07-11 1995-07-04 Vodný roztok risperidónu a spôsob jeho prípravy

Country Status (37)

Country Link
US (3) US5453425A (fr)
EP (1) EP0769965B1 (fr)
JP (1) JP2872412B2 (fr)
KR (1) KR100212942B1 (fr)
CN (1) CN1148226C (fr)
AP (1) AP774A (fr)
AT (1) ATE206931T1 (fr)
AU (1) AU684193B2 (fr)
BG (1) BG63070B1 (fr)
BR (1) BR9508253A (fr)
CA (1) CA2194564C (fr)
CY (1) CY2268B1 (fr)
CZ (1) CZ285204B6 (fr)
DE (1) DE69523313T2 (fr)
DK (1) DK0769965T3 (fr)
EE (1) EE03426B1 (fr)
ES (1) ES2165918T3 (fr)
FI (1) FI116510B (fr)
HK (1) HK1010691A1 (fr)
HR (1) HRP950397B1 (fr)
HU (1) HU222352B1 (fr)
IL (1) IL114525A (fr)
MX (1) MX9700374A (fr)
MY (1) MY114389A (fr)
NO (1) NO320366B1 (fr)
NZ (1) NZ289432A (fr)
PH (1) PH31626A (fr)
PL (1) PL179972B1 (fr)
PT (1) PT769965E (fr)
RO (1) RO116778B1 (fr)
RU (1) RU2161965C2 (fr)
SI (1) SI9500220B (fr)
SK (1) SK282159B6 (fr)
TR (1) TR199500778A1 (fr)
TW (1) TW420615B (fr)
WO (1) WO1996001652A1 (fr)
ZA (1) ZA955720B (fr)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL314481A1 (en) 1993-11-19 1996-09-16 Janssen Pharmaceutica Nv Microencapsulated substituted 3-piperidinyl 1,2-benzoisoxazoles and 1,2-benzoisothiazoles
US5453425A (en) * 1994-07-11 1995-09-26 Janssen Pharmaceutica N.V. Risperidone oral formulation
UA72189C2 (uk) * 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот
US6682758B1 (en) 1998-12-22 2004-01-27 The United States Of America As Represented By The Department Of Health And Human Services Water-insoluble drug delivery system
US6495164B1 (en) 2000-05-25 2002-12-17 Alkermes Controlled Therapeutics, Inc. I Preparation of injectable suspensions having improved injectability
US20050232995A1 (en) 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
WO2004017975A1 (fr) * 2002-08-23 2004-03-04 Ranbaxy Laboratories Limited Solutions aqueuses stables de risperidone et leurs methodes de preparation
WO2004094415A1 (fr) * 2003-04-22 2004-11-04 Synthon B.V. Monochlorhydrates de risperidone
PE20050285A1 (es) 2003-06-24 2005-06-09 Novartis Ag Composicion farmaceutica que comprende analogos ciclicos de somatostatina
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
ES2245252B1 (es) * 2004-06-15 2007-03-01 Farmalider, S.A. Solucion acuosa de risperidona para administracion oral.
ES2245891B1 (es) * 2004-07-09 2006-11-16 Clinmet S.L. "metodo para la obtencion de un excipiente universal para la administracion oral de principios activos farmaceuticos y composiciones de excipientes resultantes del metodo".
WO2006129160A2 (fr) * 2005-06-01 2006-12-07 Aurobindo Pharma Limited Solutions aqueuses stables d'un agent antipsychotique
ES2323286T3 (es) * 2005-06-29 2009-07-10 Verisfield (Uk) Ltd. Composiciones farmaceuticas de risperidona en disolucion acuosa.
US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
JP4922657B2 (ja) * 2006-05-09 2012-04-25 高田製薬株式会社 リスペリドン経口用液剤
WO2007138462A2 (fr) * 2006-06-01 2007-12-06 Wockhardt Ltd Formulations orales aqueuses de rispéridone
MX354603B (es) 2007-05-25 2018-03-13 Indivior Uk Ltd Formulaciones de transferencia sostenida de compuestos de risperidona.
US7776866B2 (en) * 2007-09-15 2010-08-17 Protia, Llc Deuterium-enriched risperidone
CN105560176A (zh) * 2007-12-19 2016-05-11 詹森药业有限公司 与长效注射用帕潘立酮酯相关的给药方案
WO2010085452A1 (fr) 2009-01-20 2010-07-29 Los Angeles Biomedical Research Institute At Harbor - Ucla Medical Center Acide sorbique et benzoïque et dérivés de celui-ci pour améliorer l'activité d'un produit neuropharmaceutique
US9272044B2 (en) 2010-06-08 2016-03-01 Indivior Uk Limited Injectable flowable composition buprenorphine
GB2481017B (en) 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
CA2850707C (fr) * 2011-10-03 2023-03-21 The University Of Utah Research Foundation Application d'antagonistes du recepteur 5-ht6 dans l'attenuation des deficits cognitifs lies au syndrome de down
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
NZ731309A (en) 2014-11-07 2022-02-25 Indivior Uk Ltd Buprenorphine dosing regimens
CN109563018A (zh) 2016-06-13 2019-04-02 心悦生医股份有限公司 苯甲酸钠的共晶及其用途
RU2765625C2 (ru) 2016-06-13 2022-02-01 Сайньюрекс Интернэшнл (Тайвань) Корп. Сокристаллы бензоата лития и их применения
BR112019005542A2 (pt) * 2016-09-23 2019-06-18 Delpor Inc composições para compostos de agente terapêutico de pequenas moléculas
RU2646812C1 (ru) * 2016-10-24 2018-03-07 Общество с ограниченной ответственностью "Трейдсервис" Жидкая лекарственная форма рисперидона и способ ее получения
US11369579B2 (en) 2016-10-24 2022-06-28 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US10336679B2 (en) 2016-10-24 2019-07-02 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US10646484B2 (en) 2017-06-16 2020-05-12 Indivior Uk Limited Methods to treat opioid use disorder
CN107260662A (zh) * 2017-06-21 2017-10-20 南京正科医药股份有限公司 一种利培酮口服溶液及其制备方法
CN107441037A (zh) * 2017-08-16 2017-12-08 南京正科医药股份有限公司 一种利培酮口服溶液
CN109589304A (zh) * 2017-10-01 2019-04-09 万特制药(海南)有限公司 利培酮口服溶液及其制备方法
US10098861B1 (en) 2017-10-24 2018-10-16 Syneurx International (Taiwan) Corp. Pharmaceutical composition comprising sodium benzoate compound and clozapine, and uses thereof
JP2021515038A (ja) * 2018-02-27 2021-06-17 デルポー・インコーポレイテッドＤｅｌｐｏｒ， Ｉｎｃ． 小分子治療剤化合物のための組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337261A (en) * 1980-07-28 1982-06-29 Hoechst-Roussel Pharmaceuticals Inc. (1,2-Benzisoxazol)phenoxyacetic acids as diuretics
IL88233A (en) * 1987-11-03 1993-08-18 Genentech Inc Gamma interferon formulation
FR2641278B1 (fr) * 1989-01-05 1991-03-22 Lipha Piperidines, procedes de preparation et medicaments les contenant
DK203990D0 (da) * 1990-08-24 1990-08-24 Novo Nordisk As Piperazinylderivater
TW376319B (en) * 1993-04-28 1999-12-11 Janssen Pharmaceutica Nv Pharmaceutical composition containing risperidone pamoate and having a long acting activity for treating psychoses induced by the release of dopamine
US5453425A (en) * 1994-07-11 1995-09-26 Janssen Pharmaceutica N.V. Risperidone oral formulation
FR2796273B1 (fr) * 1999-07-15 2003-09-12 Oreal Composition a phase grasse liquide gelifiee par un polyamide a groupements ester terminaux

Also Published As

Publication number Publication date
KR100212942B1 (ko) 1999-08-02
US5616587A (en) 1997-04-01
EE9700009A (et) 1997-08-15
TR199500778A1 (tr) 1996-10-21
AU684193B2 (en) 1997-12-04
US5453425A (en) 1995-09-26
TW420615B (en) 2001-02-01
JPH09511751A (ja) 1997-11-25
SK2297A3 (en) 1997-09-10
HU9700082D0 (en) 1997-02-28
DE69523313T2 (de) 2002-06-27
HU222352B1 (hu) 2003-06-28
MX9700374A (es) 1997-04-30
NZ289432A (en) 1998-05-27
HUT76826A (en) 1997-11-28
CN1155247A (zh) 1997-07-23
EE03426B1 (et) 2001-06-15
BG101106A (en) 1997-08-29
ZA955720B (en) 1997-01-10
MY114389A (en) 2002-10-31
CA2194564C (fr) 1997-12-16
CA2194564A1 (fr) 1996-01-25
DE69523313D1 (de) 2001-11-22
SI9500220A (en) 1996-02-29
AP9700910A0 (en) 1997-01-31
NO970051L (no) 1997-01-07
PL179972B1 (pl) 2000-11-30
FI116510B (fi) 2005-12-15
CZ285204B6 (cs) 1999-06-16
NO970051D0 (no) 1997-01-07
DK0769965T3 (da) 2002-02-04
HK1010691A1 (en) 1999-06-25
IL114525A0 (en) 1995-11-27
AP774A (en) 1999-10-28
IL114525A (en) 1999-06-20
BG63070B1 (bg) 2001-03-30
CZ2797A3 (en) 1997-07-16
AU2927595A (en) 1996-02-09
WO1996001652A1 (fr) 1996-01-25
HRP950397B1 (en) 2002-04-30
HRP950397A2 (en) 1997-10-31
KR970704472A (ko) 1997-09-06
BR9508253A (pt) 1997-12-23
USRE39181E1 (en) 2006-07-11
RO116778B1 (ro) 2001-06-29
SI9500220B (sl) 2004-12-31
PT769965E (pt) 2002-04-29
ES2165918T3 (es) 2002-04-01
ATE206931T1 (de) 2001-11-15
NO320366B1 (no) 2005-11-28
FI970109A (fi) 1997-01-10
EP0769965A1 (fr) 1997-05-02
EP0769965B1 (fr) 2001-10-17
RU2161965C2 (ru) 2001-01-20
FI970109A0 (fi) 1997-01-10
PH31626A (en) 1999-01-12
CN1148226C (zh) 2004-05-05
PL318132A1 (en) 1997-05-12
CY2268B1 (en) 2003-07-04
JP2872412B2 (ja) 1999-03-17

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Legal Events

Date Code Title Description
MK4A Patent expired

Expiry date: 20150704