DE69523313D1 - Waessrige risperidone-zusammensetzungen - Google Patents

Waessrige risperidone-zusammensetzungen

Info

Publication number
DE69523313D1
DE69523313D1 DE69523313T DE69523313T DE69523313D1 DE 69523313 D1 DE69523313 D1 DE 69523313D1 DE 69523313 T DE69523313 T DE 69523313T DE 69523313 T DE69523313 T DE 69523313T DE 69523313 D1 DE69523313 D1 DE 69523313D1
Authority
DE
Germany
Prior art keywords
risperidone compositions
aqueous
aqueous risperidone
compositions
risperidone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69523313T
Other languages
English (en)
Other versions
DE69523313T2 (de
Inventor
Ois Karel Fran
Maria Dries
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26955530&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69523313(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of DE69523313D1 publication Critical patent/DE69523313D1/de
Application granted granted Critical
Publication of DE69523313T2 publication Critical patent/DE69523313T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69523313T 1994-07-11 1995-07-04 Waessrige risperidone-zusammensetzungen Expired - Lifetime DE69523313T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/272,462 US5453425A (en) 1994-07-11 1994-07-11 Risperidone oral formulation
US08/429,435 US5616587A (en) 1994-07-11 1995-04-26 Aqueous risperidone formulations
PCT/EP1995/002615 WO1996001652A1 (en) 1994-07-11 1995-07-04 Aqueous risperidone formulations

Publications (2)

Publication Number Publication Date
DE69523313D1 true DE69523313D1 (de) 2001-11-22
DE69523313T2 DE69523313T2 (de) 2002-06-27

Family

ID=26955530

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69523313T Expired - Lifetime DE69523313T2 (de) 1994-07-11 1995-07-04 Waessrige risperidone-zusammensetzungen

Country Status (37)

Country Link
US (3) US5453425A (de)
EP (1) EP0769965B1 (de)
JP (1) JP2872412B2 (de)
KR (1) KR100212942B1 (de)
CN (1) CN1148226C (de)
AP (1) AP774A (de)
AT (1) ATE206931T1 (de)
AU (1) AU684193B2 (de)
BG (1) BG63070B1 (de)
BR (1) BR9508253A (de)
CA (1) CA2194564C (de)
CY (1) CY2268B1 (de)
CZ (1) CZ285204B6 (de)
DE (1) DE69523313T2 (de)
DK (1) DK0769965T3 (de)
EE (1) EE03426B1 (de)
ES (1) ES2165918T3 (de)
FI (1) FI116510B (de)
HK (1) HK1010691A1 (de)
HR (1) HRP950397B1 (de)
HU (1) HU222352B1 (de)
IL (1) IL114525A (de)
MX (1) MX9700374A (de)
MY (1) MY114389A (de)
NO (1) NO320366B1 (de)
NZ (1) NZ289432A (de)
PH (1) PH31626A (de)
PL (1) PL179972B1 (de)
PT (1) PT769965E (de)
RO (1) RO116778B1 (de)
RU (1) RU2161965C2 (de)
SI (1) SI9500220B (de)
SK (1) SK282159B6 (de)
TR (1) TR199500778A1 (de)
TW (1) TW420615B (de)
WO (1) WO1996001652A1 (de)
ZA (1) ZA955720B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0729357T3 (da) * 1993-11-19 2005-06-06 Janssen Pharmaceutica Nv Mikroindkapslede 1,2-benzazoler
US5453425A (en) * 1994-07-11 1995-09-26 Janssen Pharmaceutica N.V. Risperidone oral formulation
UA72189C2 (uk) 1997-11-17 2005-02-15 Янссен Фармацевтика Н.В. Фармацевтична композиція, що містить водну суспензію субмікронних ефірів 9-гідроксирисперидон жирних кислот
US6682758B1 (en) 1998-12-22 2004-01-27 The United States Of America As Represented By The Department Of Health And Human Services Water-insoluble drug delivery system
US6495164B1 (en) 2000-05-25 2002-12-17 Alkermes Controlled Therapeutics, Inc. I Preparation of injectable suspensions having improved injectability
US20050232995A1 (en) 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
US20060148826A1 (en) * 2002-08-23 2006-07-06 Ashish Gogia Stable aqueous solutions of risperidone and methods for their preparation
WO2004094414A1 (en) * 2003-04-22 2004-11-04 Synthon B.V. Water soluble salts of risperidone
PE20050285A1 (es) 2003-06-24 2005-06-09 Novartis Ag Composicion farmaceutica que comprende analogos ciclicos de somatostatina
US20050036977A1 (en) * 2003-08-11 2005-02-17 Dilip Gole Taste-masked resinate and preparation thereof
ES2245252B1 (es) * 2004-06-15 2007-03-01 Farmalider, S.A. Solucion acuosa de risperidona para administracion oral.
ES2245891B1 (es) * 2004-07-09 2006-11-16 Clinmet S.L. "metodo para la obtencion de un excipiente universal para la administracion oral de principios activos farmaceuticos y composiciones de excipientes resultantes del metodo".
WO2006129160A2 (en) * 2005-06-01 2006-12-07 Aurobindo Pharma Limited Stable aqueous oral solution of risperidone
ES2323286T3 (es) * 2005-06-29 2009-07-10 Verisfield (Uk) Ltd. Composiciones farmaceuticas de risperidona en disolucion acuosa.
US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
JP4922657B2 (ja) * 2006-05-09 2012-04-25 高田製薬株式会社 リスペリドン経口用液剤
WO2007138462A2 (en) * 2006-06-01 2007-12-06 Wockhardt Ltd Aqueous oral formulations of risperidone
MX337286B (es) * 2007-05-25 2016-02-22 Indivior Uk Ltd Formulaciones de transferencia sostenida de compuestos de risperidona.
US7776866B2 (en) * 2007-09-15 2010-08-17 Protia, Llc Deuterium-enriched risperidone
AU2008340101B2 (en) * 2007-12-19 2015-02-19 Janssen Pharmaceutica Nv Dosing regimen associated with long acting injectable paliperidone esters
BRPI1007173A2 (pt) * 2009-01-20 2016-02-23 Los Angeles Biomed Res Inst composição farmacêutica compreendendo ácido sórbico e benzóico e seus derivados que melhora a atividade de um neurofármaco, e seu uso, formulação farmacêutica e método de mitigação de um ou mais sintomas de um distúrbio neuropsiquiátrico
US9272044B2 (en) 2010-06-08 2016-03-01 Indivior Uk Limited Injectable flowable composition buprenorphine
GB2513060B (en) 2010-06-08 2015-01-07 Rb Pharmaceuticals Ltd Microparticle buprenorphine suspension
EP2763676B1 (de) * 2011-10-03 2019-12-25 The University of Utah Research Foundation Verwendung von 5-ht6-rezeptorantagonisten zur linderung von kognitiven defiziten von down-syndrom
GB201404139D0 (en) 2014-03-10 2014-04-23 Rb Pharmaceuticals Ltd Sustained release buprenorphine solution formulations
CA3015557C (en) 2014-11-07 2019-07-16 Indivior Uk Limited The use of sustained-release buprenorphine formulations for the treatment of pain or opioid use disorders
EP3468946A4 (de) 2016-06-13 2020-02-12 Syneurx International (Taiwan) Corp. Co-kristalle von lithium-benzoat und verwendungen davon
CA3027297A1 (en) 2016-06-13 2017-12-21 Syneurx International (Taiwan) Corp. Co-crystals of sodium benzoate and uses thereof
CA3037531A1 (en) * 2016-09-23 2018-03-29 Delpor, Inc. Compositions for small molecule therapeutic agent compounds
US10336679B2 (en) 2016-10-24 2019-07-02 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US11369579B2 (en) 2016-10-24 2022-06-28 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
RU2646812C1 (ru) * 2016-10-24 2018-03-07 Общество с ограниченной ответственностью "Трейдсервис" Жидкая лекарственная форма рисперидона и способ ее получения
US10646484B2 (en) 2017-06-16 2020-05-12 Indivior Uk Limited Methods to treat opioid use disorder
CN107260662A (zh) * 2017-06-21 2017-10-20 南京正科医药股份有限公司 一种利培酮口服溶液及其制备方法
CN107441037A (zh) * 2017-08-16 2017-12-08 南京正科医药股份有限公司 一种利培酮口服溶液
CN109589304A (zh) * 2017-10-01 2019-04-09 万特制药(海南)有限公司 利培酮口服溶液及其制备方法
US10098861B1 (en) 2017-10-24 2018-10-16 Syneurx International (Taiwan) Corp. Pharmaceutical composition comprising sodium benzoate compound and clozapine, and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337261A (en) * 1980-07-28 1982-06-29 Hoechst-Roussel Pharmaceuticals Inc. (1,2-Benzisoxazol)phenoxyacetic acids as diuretics
IL88233A (en) * 1987-11-03 1993-08-18 Genentech Inc Gamma interferon formulation
FR2641278B1 (fr) * 1989-01-05 1991-03-22 Lipha Piperidines, procedes de preparation et medicaments les contenant
DK203990D0 (da) * 1990-08-24 1990-08-24 Novo Nordisk As Piperazinylderivater
TW376319B (en) * 1993-04-28 1999-12-11 Janssen Pharmaceutica Nv Pharmaceutical composition containing risperidone pamoate and having a long acting activity for treating psychoses induced by the release of dopamine
US5453425A (en) * 1994-07-11 1995-09-26 Janssen Pharmaceutica N.V. Risperidone oral formulation
FR2796273B1 (fr) * 1999-07-15 2003-09-12 Oreal Composition a phase grasse liquide gelifiee par un polyamide a groupements ester terminaux

Also Published As

Publication number Publication date
HRP950397A2 (en) 1997-10-31
EP0769965A1 (de) 1997-05-02
EP0769965B1 (de) 2001-10-17
HU222352B1 (hu) 2003-06-28
TR199500778A1 (tr) 1996-10-21
HUT76826A (en) 1997-11-28
USRE39181E1 (en) 2006-07-11
AU2927595A (en) 1996-02-09
NO970051L (no) 1997-01-07
HK1010691A1 (en) 1999-06-25
AU684193B2 (en) 1997-12-04
JPH09511751A (ja) 1997-11-25
PH31626A (en) 1999-01-12
ZA955720B (en) 1997-01-10
SK2297A3 (en) 1997-09-10
EE03426B1 (et) 2001-06-15
HRP950397B1 (en) 2002-04-30
CZ285204B6 (cs) 1999-06-16
AP9700910A0 (en) 1997-01-31
RO116778B1 (ro) 2001-06-29
EE9700009A (et) 1997-08-15
CY2268B1 (en) 2003-07-04
HU9700082D0 (en) 1997-02-28
CA2194564C (en) 1997-12-16
DE69523313T2 (de) 2002-06-27
RU2161965C2 (ru) 2001-01-20
SI9500220A (en) 1996-02-29
PL318132A1 (en) 1997-05-12
KR100212942B1 (ko) 1999-08-02
TW420615B (en) 2001-02-01
AP774A (en) 1999-10-28
BR9508253A (pt) 1997-12-23
MY114389A (en) 2002-10-31
PT769965E (pt) 2002-04-29
FI970109A0 (fi) 1997-01-10
WO1996001652A1 (en) 1996-01-25
BG101106A (en) 1997-08-29
NZ289432A (en) 1998-05-27
US5616587A (en) 1997-04-01
CA2194564A1 (en) 1996-01-25
PL179972B1 (pl) 2000-11-30
ES2165918T3 (es) 2002-04-01
MX9700374A (es) 1997-04-30
NO320366B1 (no) 2005-11-28
NO970051D0 (no) 1997-01-07
US5453425A (en) 1995-09-26
CN1148226C (zh) 2004-05-05
FI970109A (fi) 1997-01-10
CN1155247A (zh) 1997-07-23
SK282159B6 (sk) 2001-11-06
KR970704472A (ko) 1997-09-06
DK0769965T3 (da) 2002-02-04
SI9500220B (sl) 2004-12-31
IL114525A0 (en) 1995-11-27
JP2872412B2 (ja) 1999-03-17
IL114525A (en) 1999-06-20
ATE206931T1 (de) 2001-11-15
CZ2797A3 (en) 1997-07-16
FI116510B (fi) 2005-12-15
BG63070B1 (bg) 2001-03-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition