SK281813B6 - Tropánové deriváty, spôsob ich prípravy, použitie a farmaceutická kompozícia s ich obsahom - Google Patents
Tropánové deriváty, spôsob ich prípravy, použitie a farmaceutická kompozícia s ich obsahom Download PDFInfo
- Publication number
- SK281813B6 SK281813B6 SK929-98A SK92998A SK281813B6 SK 281813 B6 SK281813 B6 SK 281813B6 SK 92998 A SK92998 A SK 92998A SK 281813 B6 SK281813 B6 SK 281813B6
- Authority
- SK
- Slovakia
- Prior art keywords
- tropane
- dichlorophenyl
- chlorophenyl
- normethyl
- methoxymethyl
- Prior art date
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- 201000010099 disease Diseases 0.000 claims abstract description 16
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- 239000008194 pharmaceutical composition Chemical class 0.000 claims abstract description 11
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK19496 | 1996-02-22 | ||
| PCT/EP1997/000850 WO1997030997A1 (en) | 1996-02-22 | 1997-02-21 | Tropane-derivatives, their preparation and use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK92998A3 SK92998A3 (en) | 1998-11-04 |
| SK281813B6 true SK281813B6 (sk) | 2001-08-06 |
Family
ID=8090830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK929-98A SK281813B6 (sk) | 1996-02-22 | 1997-02-21 | Tropánové deriváty, spôsob ich prípravy, použitie a farmaceutická kompozícia s ich obsahom |
Country Status (32)
| Country | Link |
|---|---|
| US (3) | US6288079B1 (ru) |
| EP (2) | EP0885220B1 (ru) |
| JP (1) | JP3238414B2 (ru) |
| KR (1) | KR100446571B1 (ru) |
| CN (1) | CN1077574C (ru) |
| AT (1) | ATE203023T1 (ru) |
| AU (1) | AU720358B2 (ru) |
| BG (1) | BG63945B1 (ru) |
| BR (1) | BR9707636A (ru) |
| CA (1) | CA2244773C (ru) |
| CZ (1) | CZ287007B6 (ru) |
| DE (1) | DE69705608T2 (ru) |
| DK (1) | DK0885220T3 (ru) |
| EE (1) | EE04751B1 (ru) |
| ES (1) | ES2159839T3 (ru) |
| GR (1) | GR3036829T3 (ru) |
| HK (1) | HK1018957A1 (ru) |
| HU (1) | HU228356B1 (ru) |
| IL (1) | IL125146A (ru) |
| IS (1) | IS1824B (ru) |
| NO (1) | NO318731B1 (ru) |
| NZ (1) | NZ330886A (ru) |
| PL (1) | PL185132B1 (ru) |
| PT (1) | PT885220E (ru) |
| RU (1) | RU2167876C2 (ru) |
| SG (1) | SG99853A1 (ru) |
| SI (1) | SI0885220T1 (ru) |
| SK (1) | SK281813B6 (ru) |
| TR (1) | TR199801641T2 (ru) |
| UA (1) | UA49872C2 (ru) |
| WO (1) | WO1997030997A1 (ru) |
| ZA (1) | ZA971525B (ru) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE494385T1 (de) * | 1998-09-30 | 2011-01-15 | Nihon Mediphysics Co Ltd | Verfahren zur herstellung von optisch aktiven tropinon-monokarbonsäurederivaten |
| AUPP627498A0 (en) | 1998-10-02 | 1998-10-22 | University Of Queensland, The | Novel peptides - i |
| WO2002102801A1 (en) * | 2001-05-23 | 2002-12-27 | Neurosearch A/S | Tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| CA2506646A1 (en) * | 2001-10-11 | 2003-04-11 | Organix, Inc. | Serotonin transport inhibitors |
| US20030114475A1 (en) * | 2001-10-31 | 2003-06-19 | Addiction Therapies, Inc. | Methods for the treatment of addiction |
| EP1453511B1 (en) * | 2001-11-30 | 2006-11-15 | Neurosearch A/S | Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases |
| CA2484482C (en) | 2002-05-30 | 2011-07-26 | Neurosearch A/S | Triple monoamine reuptake inhibitors for the treatment of chronic pain |
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| MM4A | Patent lapsed due to non-payment of maintenance fees |
Effective date: 20140221 |