ATE435216T1 - Alkylsubstituierte homopiperazinderivate und deren verwendung als monoamin neurotransmitter wiederaufnahmeinhibitoren - Google Patents

Alkylsubstituierte homopiperazinderivate und deren verwendung als monoamin neurotransmitter wiederaufnahmeinhibitoren

Info

Publication number
ATE435216T1
ATE435216T1 AT06708129T AT06708129T ATE435216T1 AT E435216 T1 ATE435216 T1 AT E435216T1 AT 06708129 T AT06708129 T AT 06708129T AT 06708129 T AT06708129 T AT 06708129T AT E435216 T1 ATE435216 T1 AT E435216T1
Authority
AT
Austria
Prior art keywords
inhibitors
reuppose
alkyl
monoamine neurotransmitter
homopiperazine derivatives
Prior art date
Application number
AT06708129T
Other languages
English (en)
Inventor
Dan Peters
Bjarne H Dahl
Gunnar M Olsen
Elsebet Ystergaard Nielsen
Jorgen Scheel-Krueger
John Paul Redrobe
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Application granted granted Critical
Publication of ATE435216T1 publication Critical patent/ATE435216T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
AT06708129T 2005-02-10 2006-02-09 Alkylsubstituierte homopiperazinderivate und deren verwendung als monoamin neurotransmitter wiederaufnahmeinhibitoren ATE435216T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65121705P 2005-02-10 2005-02-10
DKPA200500197 2005-02-10
PCT/EP2006/050785 WO2006084870A2 (en) 2005-02-10 2006-02-09 Alkyl substituted homopiperazine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Publications (1)

Publication Number Publication Date
ATE435216T1 true ATE435216T1 (de) 2009-07-15

Family

ID=36754327

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06708129T ATE435216T1 (de) 2005-02-10 2006-02-09 Alkylsubstituierte homopiperazinderivate und deren verwendung als monoamin neurotransmitter wiederaufnahmeinhibitoren

Country Status (5)

Country Link
US (1) US7923444B2 (de)
EP (1) EP1851207B1 (de)
AT (1) ATE435216T1 (de)
DE (1) DE602006007550D1 (de)
WO (1) WO2006084870A2 (de)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3247206A (en) 1962-10-05 1966-04-19 Ciba Geigy Corp Diaza-cycloalkane synthesis
BE628766A (de) 1962-12-26
CA1335591C (en) * 1988-05-23 1995-05-16 James Arthur Nixon Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes
EE04751B1 (et) 1996-02-22 2006-12-15 Neurosearch A/S Tropaani derivaadid, nende valmistamine ja kasutamine
GB9726736D0 (en) 1997-12-18 1998-02-18 Zeneca Ltd Chemical compounds
GB9900078D0 (en) 1999-01-05 1999-02-24 Zeneca Ltd Chemical compounds
SE9904724D0 (sv) * 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
UA81749C2 (uk) 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
EP1560813B1 (de) 2002-11-01 2010-03-17 NeuroSearch A/S Neue piperidinderivate und deren verwendung als monoaminneurotransmitter-wiederaufnahmehemmer
CA2570064A1 (en) 2004-06-18 2005-12-29 Neurosearch A/S Novel alkyl substituted piperazine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Also Published As

Publication number Publication date
US7923444B2 (en) 2011-04-12
EP1851207A2 (de) 2007-11-07
WO2006084870A2 (en) 2006-08-17
WO2006084870A3 (en) 2006-11-23
DE602006007550D1 (de) 2009-08-13
EP1851207B1 (de) 2009-07-01
US20080132489A1 (en) 2008-06-05

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties