MX2009005916A - Nuevos derivados de cromen-2-ona y su uso como inhibidores de la reabsorcion del neurotransmisor de monoamina. - Google Patents

Nuevos derivados de cromen-2-ona y su uso como inhibidores de la reabsorcion del neurotransmisor de monoamina.

Info

Publication number
MX2009005916A
MX2009005916A MX2009005916A MX2009005916A MX2009005916A MX 2009005916 A MX2009005916 A MX 2009005916A MX 2009005916 A MX2009005916 A MX 2009005916A MX 2009005916 A MX2009005916 A MX 2009005916A MX 2009005916 A MX2009005916 A MX 2009005916A
Authority
MX
Mexico
Prior art keywords
derivatives
uptake inhibitors
monoamine neurotransmitter
novel chromen
chromen
Prior art date
Application number
MX2009005916A
Other languages
English (en)
Inventor
Dan Peters
Gunnar M Olsen
Elsebet Oestergaard Nielsen
John Paul Redrobe
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of MX2009005916A publication Critical patent/MX2009005916A/es

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    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
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    • A61P25/32—Alcohol-abuse
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Esta invención se refiere a nuevos derivados de cromen-2-ona de la fórmula (I) útiles como inhibidores de la reabsorción del neurotransmisor de monoamina. En otros aspectos, la invención se refiere al uso de estos compuestos en un método para terapia y a composiciones farmacéuticas que comprenden los compuestos de la invención. (ver fórmula (I)).
MX2009005916A 2006-12-20 2007-12-18 Nuevos derivados de cromen-2-ona y su uso como inhibidores de la reabsorcion del neurotransmisor de monoamina. MX2009005916A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87580506P 2006-12-20 2006-12-20
DKPA200601679 2006-12-20
PCT/EP2007/064131 WO2008074798A1 (en) 2006-12-20 2007-12-18 Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Publications (1)

Publication Number Publication Date
MX2009005916A true MX2009005916A (es) 2009-06-19

Family

ID=39289568

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009005916A MX2009005916A (es) 2006-12-20 2007-12-18 Nuevos derivados de cromen-2-ona y su uso como inhibidores de la reabsorcion del neurotransmisor de monoamina.

Country Status (7)

Country Link
US (1) US20090312364A1 (es)
EP (1) EP2121678B1 (es)
JP (1) JP2010513392A (es)
AU (1) AU2007336291A1 (es)
CA (1) CA2673454A1 (es)
MX (1) MX2009005916A (es)
WO (1) WO2008074798A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200800980A (en) 2006-02-17 2008-01-01 Neurosearch As Novel compounds
WO2008074797A1 (en) 2006-12-20 2008-06-26 Neurosearch A/S Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
TW200904815A (en) 2007-05-09 2009-02-01 Neurosearch As Novel compounds
CN102428083A (zh) 2009-05-15 2012-04-25 神经研究公司 色原烯-2-酮衍生物及其作为单胺神经递质再摄取抑制剂的用途
US20130040985A1 (en) 2010-01-29 2013-02-14 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
US9617268B2 (en) * 2011-12-30 2017-04-11 Ptc Therapeutics, Inc. Compounds for treating spinal muscular atrophy
MA45276A (fr) * 2015-06-18 2018-04-25 Sage Therapeutics Inc Solutions de stéroïdes neuroactifs et leurs méthodes d'utilisation
WO2021023805A1 (en) * 2019-08-06 2021-02-11 Initiator Pharma A/S Compound for combination treatment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2488635C (en) * 2002-06-12 2012-10-23 Abbott Laboratories Antagonists of melanin concentrating hormone receptor
KR20070061846A (ko) * 2004-09-30 2007-06-14 뉴로서치 에이/에스 신규한 크로멘-2-온 유도체 및 모노아민 신경전달물질재흡수 억제제로서의 이의 용도
WO2006035034A1 (en) * 2004-09-30 2006-04-06 Neurosearch A/S Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
BRPI0519921A2 (pt) * 2004-12-17 2009-08-11 Neurosearch As composto enanciopuro ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica,e, uso de composto quìmico ou de um sal farmaceuticamente aceitável do mesmo
TW200800980A (en) * 2006-02-17 2008-01-01 Neurosearch As Novel compounds
CA2734797A1 (en) * 2008-08-21 2010-02-25 Neurosearch A/S Treatment of anxiety disorders

Also Published As

Publication number Publication date
JP2010513392A (ja) 2010-04-30
US20090312364A1 (en) 2009-12-17
WO2008074798A1 (en) 2008-06-26
CA2673454A1 (en) 2008-06-26
AU2007336291A1 (en) 2008-06-26
EP2121678B1 (en) 2010-11-03
EP2121678A1 (en) 2009-11-25

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