SK281120B6 - Močoviny alebo uretány, spôsob ich prípravy a farmaceutické prípravky na ich báze - Google Patents

Močoviny alebo uretány, spôsob ich prípravy a farmaceutické prípravky na ich báze Download PDF

Info

Publication number
SK281120B6
SK281120B6 SK491-94A SK49194A SK281120B6 SK 281120 B6 SK281120 B6 SK 281120B6 SK 49194 A SK49194 A SK 49194A SK 281120 B6 SK281120 B6 SK 281120B6
Authority
SK
Slovakia
Prior art keywords
carboxy
amino
carbonyl
alanine
oxoheptyl
Prior art date
Application number
SK491-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK49194A3 (en
Inventor
Semiramis Ayral-Kaloustian
Steven R. Schow
Mila T. Du
Gibbons James J., Jr.
Original Assignee
American Cyanamid Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Company filed Critical American Cyanamid Company
Publication of SK49194A3 publication Critical patent/SK49194A3/sk
Publication of SK281120B6 publication Critical patent/SK281120B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SK491-94A 1993-05-12 1994-04-28 Močoviny alebo uretány, spôsob ich prípravy a farmaceutické prípravky na ich báze SK281120B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/063,174 US5312831A (en) 1993-05-12 1993-05-12 Urethanes and ureas that induce cytokine production

Publications (2)

Publication Number Publication Date
SK49194A3 SK49194A3 (en) 1995-02-08
SK281120B6 true SK281120B6 (sk) 2000-12-11

Family

ID=22047440

Family Applications (1)

Application Number Title Priority Date Filing Date
SK491-94A SK281120B6 (sk) 1993-05-12 1994-04-28 Močoviny alebo uretány, spôsob ich prípravy a farmaceutické prípravky na ich báze

Country Status (26)

Country Link
US (6) US5312831A (ja)
EP (1) EP0652228B1 (ja)
JP (1) JP3583469B2 (ja)
KR (1) KR100296543B1 (ja)
CN (1) CN1094943C (ja)
AT (1) ATE144533T1 (ja)
AU (1) AU669064B2 (ja)
CA (1) CA2123261A1 (ja)
CZ (1) CZ290445B6 (ja)
DE (1) DE69400798T2 (ja)
DK (1) DK0652228T3 (ja)
ES (1) ES2094004T3 (ja)
FI (1) FI942186A (ja)
GR (1) GR3022253T3 (ja)
HU (1) HU219768B (ja)
IL (1) IL109602A (ja)
NO (1) NO311223B1 (ja)
NZ (1) NZ260507A (ja)
PH (1) PH30182A (ja)
PL (1) PL179984B1 (ja)
RU (1) RU2135515C1 (ja)
SG (1) SG43071A1 (ja)
SI (1) SI0652228T1 (ja)
SK (1) SK281120B6 (ja)
TW (1) TW380129B (ja)
ZA (1) ZA943266B (ja)

Families Citing this family (35)

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BE1007183A3 (fr) * 1993-06-18 1995-04-18 Solvay Ureines derivees d'alpha, omega-diaminoacides et procede pour leur preparation.
EP0809492A4 (en) 1995-02-17 2007-01-24 Smithkline Beecham Corp IL-8 RECEPTOR ANTAGONISTS
US6005008A (en) * 1996-02-16 1999-12-21 Smithkline Beecham Corporation IL-8 receptor antagonists
US6262113B1 (en) 1996-03-20 2001-07-17 Smithkline Beecham Corporation IL-8 receptor antagonists
US6211373B1 (en) 1996-03-20 2001-04-03 Smithkline Beecham Corporation Phenyl urea antagonists of the IL-8 receptor
HUP9903922A3 (en) 1996-06-27 2001-12-28 Smithkline Beecham Corp Il-8 receptor antagonists
IL127666A0 (en) * 1996-06-27 1999-10-28 Smithkline Beecham Corp IL-8 receptor antagonists
WO1998006398A1 (en) * 1996-08-15 1998-02-19 Smithkline Beecham Corporation Il-8 receptor antagonists
KR100589474B1 (ko) * 1998-03-26 2006-06-14 산텐 세이야꾸 가부시키가이샤 신규한 우레아 유도체
US7465754B1 (en) 1999-09-15 2008-12-16 Wyeth Method of potentiating chemotherapy and treating solid tumors
US7332158B2 (en) 2002-05-29 2008-02-19 Demao Yang Compositions and treatments for myelosuppression by ex vivo activated immune cells
US7048922B2 (en) * 2002-05-29 2006-05-23 Demao Yang Stimulation of hematopoiesis by ex vivo activated immune cells
AR041834A1 (es) * 2002-10-29 2005-06-01 Smithkline Beecham Corp Compuesto de difenilurea sustituido con sulfonamida, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion
US20060057121A1 (en) * 2004-09-10 2006-03-16 Demao Yang Compositions and treatments using ex vivo activated cells for myelosuppressed patients
CN101495113A (zh) * 2006-04-21 2009-07-29 史密丝克莱恩比彻姆公司 Il-8受体拮抗剂
US20090093451A1 (en) * 2006-04-21 2009-04-09 Smithkline Beecham Corporation IL-8 Receptor Antagonists
CL2007001829A1 (es) * 2006-06-23 2008-01-25 Smithkline Beecham Corp P-toluensulfonato de n-[4-cloro-2-hidroxi-3-(piperazina-1-sulfonil)fenil]-n-(2-cloro-3-fluorofenil)urea;procedimiento de preparacion;composicion farmaceutica;combinacion farmaceutica;y uso en el tratamiento de una enfermedad mediada por la quiimioquina il-8, tales como asma y epoc.
EP2830438B1 (en) 2012-03-30 2019-09-04 Givaudan SA N-acyl derivatives of gamma amino-butyric acid as food flavouring compounds, powder compositions containing them
SG11201405340XA (en) 2012-03-30 2014-10-30 Givaudan Sa N-acylated methionine derivatives as food flavouring compounds
WO2013148997A1 (en) 2012-03-30 2013-10-03 Givaudan, S.A. N-acylated 1 - aminocycloalkyl carboxylic acids as food flavouring compounds
WO2013149025A1 (en) * 2012-03-30 2013-10-03 Givaudan, S., A. N-acyl serine derivatives as food flavouring compounds
BR112014023016B1 (pt) 2012-03-30 2020-10-27 Givaudan Sa composição de sabor e composição comestível
CN104302191A (zh) 2012-03-30 2015-01-21 奇华顿股份有限公司 用于改善可食用组合物香味特性的n-酰基-氨基酸衍生物
BR112014024157B1 (pt) 2012-03-30 2020-12-15 Givaudan Sa Composição comestível, solução de estoque e método para complementar as características de sabor ou paladar de produtos comestíveis
EP2830441B1 (en) 2012-03-30 2019-11-13 Givaudan SA N-acyl derivatives of gamma amino-butyric acid as food flavouring compounds
US20160227825A1 (en) 2013-10-02 2016-08-11 Givaudan Sa Organic Compounds having Taste-Modifying Properties
CN105636934B (zh) 2013-10-02 2019-03-29 奇华顿股份有限公司 N-酰化的2-氨基异丁酸化合物和包含它们的香味组合物
WO2015050535A1 (en) 2013-10-02 2015-04-09 Givaudan S.A. Organic compounds
WO2015048990A1 (en) 2013-10-02 2015-04-09 Givaudan Sa Organic compounds having taste-modifying properties
GB201317424D0 (en) 2013-10-02 2013-11-13 Givaudan Sa Improvements in or relating to organic compounds
CN105658089B (zh) 2013-10-02 2019-07-09 奇华顿股份有限公司 有机化合物
EP3057448B1 (en) 2013-10-02 2017-12-06 Givaudan S.A. Organic compounds having taste-modifying properties
CN105592719B (zh) 2013-10-02 2020-03-10 奇华顿股份有限公司 有机化合物
EP3672939A1 (en) 2017-08-21 2020-07-01 Celgene Corporation Processes for preparation of (s)-tert-butyl 4,5-diamino-5-oxopentanoate
CN109601739B (zh) * 2019-01-17 2022-10-14 河南湾流生物科技有限公司 一种复合氨基酸饲料添加剂及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2033906B (en) * 1978-10-19 1982-12-01 Anvar Water-soluble compounds derived from extracts of streptomyces stimulosus process for their production and compositions containing them
US4349466A (en) * 1978-11-14 1982-09-14 Fujisawa Pharmaceutical Co Peptide, process for preparation thereof and use thereof
US4725582A (en) * 1978-11-14 1988-02-16 Fujisawa Pharmaceutical Company, Ltd. Peptide, process for preparation thereof and use thereof
FR2460290A1 (fr) * 1979-06-29 1981-01-23 Rhone Poulenc Ind Nouveaux tetra- ou pentapeptides, leur preparation et les medicaments qui les contiennent
WO1993005780A1 (en) * 1991-09-27 1993-04-01 Board Of Regents, The University Of Texas System Amino acids containing parenteral formulations for the treatment of hypotension and related pathologies

Also Published As

Publication number Publication date
FI942186A0 (fi) 1994-05-11
DK0652228T3 (da) 1996-11-25
CN1094943C (zh) 2002-11-27
CZ98194A3 (en) 1994-12-15
RU2135515C1 (ru) 1999-08-27
SK49194A3 (en) 1995-02-08
ZA943266B (en) 1995-01-12
DE69400798D1 (de) 1996-11-28
NO941786L (no) 1994-11-14
IL109602A0 (en) 1994-08-26
CA2123261A1 (en) 1994-11-13
HU9401444D0 (en) 1994-08-29
EP0652228A1 (en) 1995-05-10
NO311223B1 (no) 2001-10-29
HUT67038A (en) 1995-01-30
SI0652228T1 (en) 1997-10-31
CZ290445B6 (cs) 2002-07-17
NO941786D0 (no) 1994-05-11
SG43071A1 (en) 1997-10-17
JP3583469B2 (ja) 2004-11-04
US5312831A (en) 1994-05-17
US5545662A (en) 1996-08-13
KR100296543B1 (ko) 2001-11-22
US5616612A (en) 1997-04-01
ATE144533T1 (de) 1996-11-15
GR3022253T3 (en) 1997-04-30
AU6304394A (en) 1994-11-17
HU219768B (hu) 2001-07-30
US5658945A (en) 1997-08-19
NZ260507A (en) 1996-02-27
PL179984B1 (pl) 2000-11-30
TW380129B (en) 2000-01-21
FI942186A (fi) 1994-11-13
IL109602A (en) 2000-06-01
ES2094004T3 (es) 1997-01-01
US5633280A (en) 1997-05-27
DE69400798T2 (de) 1997-03-13
EP0652228B1 (en) 1996-10-23
JPH07179414A (ja) 1995-07-18
CN1100413A (zh) 1995-03-22
PH30182A (en) 1997-01-21
US5602275A (en) 1997-02-11
AU669064B2 (en) 1996-05-23

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