SK281035B6 - Spôsob prípravy esterov baccatínu iii alebo 10-desacetylbaccatínu iii, ester baccatínu iii alebo 10-desacetylbaccatínu iii a medziprodukt na uvedený spôsob - Google Patents
Spôsob prípravy esterov baccatínu iii alebo 10-desacetylbaccatínu iii, ester baccatínu iii alebo 10-desacetylbaccatínu iii a medziprodukt na uvedený spôsob Download PDFInfo
- Publication number
- SK281035B6 SK281035B6 SK438-95A SK43895A SK281035B6 SK 281035 B6 SK281035 B6 SK 281035B6 SK 43895 A SK43895 A SK 43895A SK 281035 B6 SK281035 B6 SK 281035B6
- Authority
- SK
- Slovakia
- Prior art keywords
- group
- iii
- carbon atoms
- formula
- atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9211739A FR2696464B1 (fr) | 1992-10-05 | 1992-10-05 | Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III. |
| PCT/FR1993/000965 WO1994007876A1 (fr) | 1992-10-05 | 1993-10-04 | Nouveau procede d'esterification de la baccatine iii et de la desacetyl-10 baccatine iii |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK43895A3 SK43895A3 (en) | 1995-08-09 |
| SK281035B6 true SK281035B6 (sk) | 2000-11-07 |
Family
ID=9434116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK438-95A SK281035B6 (sk) | 1992-10-05 | 1993-10-04 | Spôsob prípravy esterov baccatínu iii alebo 10-desacetylbaccatínu iii, ester baccatínu iii alebo 10-desacetylbaccatínu iii a medziprodukt na uvedený spôsob |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US5717103A (ru) |
| EP (1) | EP0663905B1 (ru) |
| JP (1) | JP3064419B2 (ru) |
| KR (1) | KR100290663B1 (ru) |
| AT (1) | ATE147734T1 (ru) |
| AU (1) | AU689446B2 (ru) |
| CA (1) | CA2146372C (ru) |
| CZ (1) | CZ284818B6 (ru) |
| DE (1) | DE69307526T2 (ru) |
| DK (1) | DK0663905T3 (ru) |
| ES (1) | ES2096328T3 (ru) |
| FI (1) | FI115909B (ru) |
| FR (1) | FR2696464B1 (ru) |
| GR (1) | GR3022286T3 (ru) |
| HU (1) | HU225973B1 (ru) |
| MX (1) | MX9305764A (ru) |
| NO (1) | NO313141B1 (ru) |
| NZ (1) | NZ256443A (ru) |
| PL (1) | PL178090B1 (ru) |
| RU (1) | RU2123493C1 (ru) |
| SK (1) | SK281035B6 (ru) |
| TW (1) | TW372234B (ru) |
| WO (1) | WO1994007876A1 (ru) |
| ZA (1) | ZA937316B (ru) |
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| US6794523B2 (en) | 1991-09-23 | 2004-09-21 | Florida State University | Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them |
| FR2697522B1 (fr) * | 1992-10-30 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
| FR2698361B1 (fr) * | 1992-11-20 | 1995-01-13 | Rhone Poulenc Rorer Sa | Procédé de préparation d'un acide oxazolidine-1,3 carboxylique-5. |
| IL107950A (en) | 1992-12-15 | 2001-04-30 | Upjohn Co | b 7, b 8 - Matano - Taxols, their preparation and pharmaceutical preparations against malignant tumors containing them |
| ES2145829T3 (es) * | 1993-06-11 | 2000-07-16 | Upjohn Co | Uso antineoplasico de delta 6,7-taxoles y composiciones farmaceuticas que los contienen. |
| DE69435342D1 (de) | 1993-07-19 | 2011-05-05 | Angiotech Pharm Inc | Anti-Angiogene Mittel und Verfahren zu deren Verwendung |
| JPH09505050A (ja) * | 1993-11-12 | 1997-05-20 | ジ・アップジョン・カンパニー | ピリミジン−チオアルキルおよびアルキルエーテル化合物 |
| IL127599A (en) * | 1994-01-28 | 2004-06-01 | Upjohn Co | Process for preparing isotaxol analogs |
| CA2178541C (en) | 1995-06-07 | 2009-11-24 | Neal E. Fearnot | Implantable medical device |
| CZ293508B6 (cs) * | 1996-05-08 | 2004-05-12 | Pharmaciaá@Áupjohnácompany | Fenylisoserinestery silylového baccatinu III |
| US6150537A (en) * | 1997-12-12 | 2000-11-21 | Emory University | Methods for the esterification of alcohols and compounds useful therefor as potential anticancer agents |
| WO2002085337A1 (en) | 2001-04-20 | 2002-10-31 | The University Of British Columbia | Micellar drug delivery systems for hydrophobic drugs |
| JP4502338B2 (ja) * | 1999-09-17 | 2010-07-14 | 株式会社横浜国際バイオ研究所 | タキソイド化合物の製造法 |
| AU775373B2 (en) | 1999-10-01 | 2004-07-29 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| CA2307393A1 (en) | 2000-05-01 | 2001-11-01 | The University Of British Columbia | Ginsenoside chemotherapy |
| EP1318794A2 (en) | 2000-09-22 | 2003-06-18 | Bristol-Myers Squibb Company | Method for reducing toxicity of combined chemotherapies |
| CA2440935A1 (en) * | 2001-03-13 | 2002-09-19 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
| US20030157170A1 (en) * | 2001-03-13 | 2003-08-21 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
| US7351542B2 (en) | 2002-05-20 | 2008-04-01 | The Regents Of The University Of California | Methods of modulating tubulin deacetylase activity |
| JP2006516548A (ja) | 2002-12-30 | 2006-07-06 | アンジオテック インターナショナル アクツィエン ゲゼルシャフト | 迅速ゲル化ポリマー組成物からの薬物送達法 |
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| WO2006089209A2 (en) | 2005-02-17 | 2006-08-24 | The Board Of Trustees Of The Leland Stanford Junior University | Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby |
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| PL388144A1 (pl) | 2009-05-29 | 2010-12-06 | Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością | Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie |
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Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US34277A (en) * | 1862-01-28 | Improvement in lamps | ||
| US4942184A (en) * | 1988-03-07 | 1990-07-17 | The United States Of America As Represented By The Department Of Health And Human Services | Water soluble, antineoplastic derivatives of taxol |
| FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
| USRE34277E (en) * | 1988-04-06 | 1993-06-08 | Centre National De La Recherche Scientifique | Process for preparing taxol |
| MX9102128A (es) * | 1990-11-23 | 1992-07-08 | Rhone Poulenc Rorer Sa | Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene |
| FR2696460B1 (fr) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
| FR2696458B1 (fr) * | 1992-10-05 | 1994-11-10 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
-
1992
- 1992-10-05 FR FR9211739A patent/FR2696464B1/fr not_active Expired - Fee Related
-
1993
- 1993-09-21 MX MX9305764A patent/MX9305764A/es unknown
- 1993-10-01 ZA ZA937316A patent/ZA937316B/xx unknown
- 1993-10-02 TW TW082108116A patent/TW372234B/zh not_active IP Right Cessation
- 1993-10-04 ES ES93921980T patent/ES2096328T3/es not_active Expired - Lifetime
- 1993-10-04 KR KR1019950701300A patent/KR100290663B1/ko not_active IP Right Cessation
- 1993-10-04 US US08/411,691 patent/US5717103A/en not_active Expired - Lifetime
- 1993-10-04 RU RU95110766A patent/RU2123493C1/ru active
- 1993-10-04 WO PCT/FR1993/000965 patent/WO1994007876A1/fr active IP Right Grant
- 1993-10-04 PL PL93308239A patent/PL178090B1/pl unknown
- 1993-10-04 HU HU9500970A patent/HU225973B1/hu unknown
- 1993-10-04 DK DK93921980.4T patent/DK0663905T3/da active
- 1993-10-04 CZ CZ95839A patent/CZ284818B6/cs not_active IP Right Cessation
- 1993-10-04 DE DE69307526T patent/DE69307526T2/de not_active Expired - Lifetime
- 1993-10-04 AU AU51148/93A patent/AU689446B2/en not_active Expired
- 1993-10-04 CA CA002146372A patent/CA2146372C/fr not_active Expired - Lifetime
- 1993-10-04 SK SK438-95A patent/SK281035B6/sk not_active IP Right Cessation
- 1993-10-04 EP EP93921980A patent/EP0663905B1/fr not_active Expired - Lifetime
- 1993-10-04 NZ NZ256443A patent/NZ256443A/en not_active IP Right Cessation
- 1993-10-04 JP JP6508785A patent/JP3064419B2/ja not_active Expired - Lifetime
- 1993-10-04 AT AT93921980T patent/ATE147734T1/de active
-
1995
- 1995-03-29 NO NO19951200A patent/NO313141B1/no not_active IP Right Cessation
- 1995-04-04 FI FI951593A patent/FI115909B/fi not_active IP Right Cessation
-
1997
- 1997-01-16 GR GR960402654T patent/GR3022286T3/el unknown
- 1997-10-31 US US08/962,452 patent/US5977375A/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4A | Patent expired |
Expiry date: 20131004 |