SK26999A3 - Stereospecific preparation of chiral 1-aryl- and 1-heteroaryl-2- -substituted ethyl-2-amines - Google Patents

Stereospecific preparation of chiral 1-aryl- and 1-heteroaryl-2- -substituted ethyl-2-amines Download PDF

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Publication number
SK26999A3
SK26999A3 SK269-99A SK26999A SK26999A3 SK 26999 A3 SK26999 A3 SK 26999A3 SK 26999 A SK26999 A SK 26999A SK 26999 A3 SK26999 A3 SK 26999A3
Authority
SK
Slovakia
Prior art keywords
optionally substituted
compound
reaction
formula
substituted aryl
Prior art date
Application number
SK269-99A
Other languages
English (en)
Slovak (sk)
Inventor
Luc Grondard
Jean-Paul Casimir
Patrick Leon
Michael K O'brien
Matthew R Powers
Daniel Robin
Original Assignee
Rhone Poulenc Rorer Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Pharma filed Critical Rhone Poulenc Rorer Pharma
Publication of SK26999A3 publication Critical patent/SK26999A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/38—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28—Halogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/22—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C07D203/24—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK269-99A 1996-09-12 1997-09-10 Stereospecific preparation of chiral 1-aryl- and 1-heteroaryl-2- -substituted ethyl-2-amines SK26999A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2600596P 1996-09-12 1996-09-12
PCT/US1997/015729 WO1998011064A1 (fr) 1996-09-12 1997-09-10 Preparation stereospecifique de 1-aryl- et 1-heteroaryl-2-substituees ethyl-2-amines chirales

Publications (1)

Publication Number Publication Date
SK26999A3 true SK26999A3 (en) 1999-10-08

Family

ID=21829300

Family Applications (1)

Application Number Title Priority Date Filing Date
SK269-99A SK26999A3 (en) 1996-09-12 1997-09-10 Stereospecific preparation of chiral 1-aryl- and 1-heteroaryl-2- -substituted ethyl-2-amines

Country Status (20)

Country Link
US (2) US6127550A (fr)
EP (1) EP0942900A4 (fr)
JP (1) JP2001501922A (fr)
KR (1) KR100317871B1 (fr)
CN (2) CN1112354C (fr)
AP (1) AP937A (fr)
AU (1) AU732332B2 (fr)
BG (1) BG103259A (fr)
BR (1) BR9711466A (fr)
CA (1) CA2265886A1 (fr)
EA (1) EA001364B1 (fr)
HK (1) HK1022296A1 (fr)
HU (1) HUP0000219A3 (fr)
IL (1) IL128813A0 (fr)
NO (1) NO991023L (fr)
OA (1) OA10991A (fr)
PL (1) PL331933A1 (fr)
SK (1) SK26999A3 (fr)
UA (1) UA54451C2 (fr)
WO (1) WO1998011064A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU225504B1 (en) * 1997-05-13 2007-01-29 Sanofi Aventis Novel halophenyl-(2-(2-thienyl)-ethylamino)-acetonitriles and process for producing them
CN1383427A (zh) 1998-12-31 2002-12-04 阿温蒂斯药物公司 制备n6－取代的脱氮杂一腺苷衍生物的方法
KR100426030B1 (ko) * 2000-07-22 2004-04-03 (주) 한켐 락톤계 당화합물에서의 키랄성 전환방법
KR100440461B1 (ko) * 2000-08-19 2004-07-15 (주) 한켐 1,4-락톤을 이용한 ｌ-리보오스의 제조 방법
KR100433179B1 (ko) * 2001-11-10 2004-05-27 주식회사 삼천리제약 2-데옥시-ｌ-리보오스의 제조방법
CN100506919C (zh) * 2006-02-23 2009-07-01 中国科学院化学研究所 使用人血清蛋白对非手性菁染料聚集体进行手性诱导的方法
JP7229158B2 (ja) 2017-06-09 2023-02-27 中外製薬株式会社 Ｎ－置換アミノ酸を含むペプチドの合成方法
WO2020111238A1 (fr) * 2018-11-30 2020-06-04 中外製薬株式会社 Procédé de déprotection et procédé d'élimination de résine dans une réaction en phase solide d'un composé peptidique ou d'un composé amide, et procédé de production d'un composé peptidique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3431152A (en) * 1967-03-23 1969-03-04 American Cyanamid Co Compositions containing aromatic sulfonyl aziridine as curing agents
US4933470A (en) * 1987-10-05 1990-06-12 Neorx Corporation Method of synthesis of vicinal diamines
CA2092305C (fr) * 1990-09-25 2003-02-11 Alfred P. Spada Composes antihypertenseurs et anti-ischemiques

Also Published As

Publication number Publication date
CN1388119A (zh) 2003-01-01
CN1112354C (zh) 2003-06-25
EA001364B1 (ru) 2001-02-26
BR9711466A (pt) 1999-08-24
PL331933A1 (en) 1999-08-16
NO991023D0 (no) 1999-03-02
US6127550A (en) 2000-10-03
AP9901476A0 (en) 1999-03-31
EP0942900A1 (fr) 1999-09-22
US6433172B1 (en) 2002-08-13
CN1230176A (zh) 1999-09-29
BG103259A (bg) 2000-02-29
OA10991A (en) 2001-11-07
EA199900281A1 (ru) 1999-08-26
WO1998011064A1 (fr) 1998-03-19
EP0942900A4 (fr) 2004-08-04
AU732332B2 (en) 2001-04-12
IL128813A0 (en) 2000-01-31
JP2001501922A (ja) 2001-02-13
NO991023L (no) 1999-03-02
AP937A (en) 2001-02-07
HUP0000219A2 (hu) 2000-12-28
AU4256297A (en) 1998-04-02
KR20000036007A (ko) 2000-06-26
CA2265886A1 (fr) 1998-03-19
HK1022296A1 (en) 2000-08-04
HUP0000219A3 (en) 2001-04-28
UA54451C2 (uk) 2003-03-17
KR100317871B1 (ko) 2002-01-18

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