SK18102002A3 - Substituované chinazolínové deriváty, ich použitie a kompozícia obsahujúca tieto deriváty - Google Patents

Substituované chinazolínové deriváty, ich použitie a kompozícia obsahujúca tieto deriváty Download PDF

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Publication number
SK18102002A3
SK18102002A3 SK1810-2002A SK18102002A SK18102002A3 SK 18102002 A3 SK18102002 A3 SK 18102002A3 SK 18102002 A SK18102002 A SK 18102002A SK 18102002 A3 SK18102002 A3 SK 18102002A3
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SK
Slovakia
Prior art keywords
alkyl
group
compound
mmol
alkoxy
Prior art date
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SK1810-2002A
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English (en)
Slovak (sk)
Inventor
Andrew Mortlock
Frederic Jung
Original Assignee
Astrazeneca Ab
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Filing date
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Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of SK18102002A3 publication Critical patent/SK18102002A3/sk

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK1810-2002A 2000-06-28 2001-06-21 Substituované chinazolínové deriváty, ich použitie a kompozícia obsahujúca tieto deriváty SK18102002A3 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00401842 2000-06-28
PCT/SE2001/001450 WO2002000649A1 (en) 2000-06-28 2001-06-21 Substituted quinazoline derivatives and their use as inhibitors

Publications (1)

Publication Number Publication Date
SK18102002A3 true SK18102002A3 (sk) 2003-07-01

Family

ID=8173742

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1810-2002A SK18102002A3 (sk) 2000-06-28 2001-06-21 Substituované chinazolínové deriváty, ich použitie a kompozícia obsahujúca tieto deriváty

Country Status (27)

Country Link
US (2) US6919338B2 (zh)
EP (1) EP1299381B1 (zh)
JP (1) JP2004501914A (zh)
KR (1) KR20030014411A (zh)
CN (1) CN1267431C (zh)
AR (1) AR030432A1 (zh)
AT (1) ATE394102T1 (zh)
AU (1) AU2001266505A1 (zh)
BG (1) BG107376A (zh)
BR (1) BR0111754A (zh)
CA (1) CA2412592A1 (zh)
CZ (1) CZ20024120A3 (zh)
DE (1) DE60133897D1 (zh)
EE (1) EE200200715A (zh)
ES (1) ES2305081T3 (zh)
HK (1) HK1053124A1 (zh)
HU (1) HUP0301236A2 (zh)
IL (1) IL153246A0 (zh)
IS (1) IS6656A (zh)
MX (1) MXPA02011974A (zh)
NO (1) NO20026010L (zh)
NZ (1) NZ522696A (zh)
PL (1) PL360439A1 (zh)
RU (1) RU2283311C2 (zh)
SK (1) SK18102002A3 (zh)
WO (1) WO2002000649A1 (zh)
ZA (1) ZA200209412B (zh)

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CN1496364A (zh) 2004-05-12
BG107376A (bg) 2003-09-30
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RU2283311C2 (ru) 2006-09-10
DE60133897D1 (de) 2008-06-19
EP1299381B1 (en) 2008-05-07
CZ20024120A3 (cs) 2003-03-12
AU2001266505A1 (en) 2002-01-08
NZ522696A (en) 2004-08-27
US20030187002A1 (en) 2003-10-02
CN1267431C (zh) 2006-08-02
NO20026010D0 (no) 2002-12-13
IL153246A0 (en) 2003-07-06
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BR0111754A (pt) 2003-04-29
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EP1299381A1 (en) 2003-04-09
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US20060046987A1 (en) 2006-03-02
ATE394102T1 (de) 2008-05-15
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CA2412592A1 (en) 2002-01-03
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