SK134398A3 - Aqueous solution of the pyridoxylated polymerized hemoglobin and method for preparing the same - Google Patents

Aqueous solution of the pyridoxylated polymerized hemoglobin and method for preparing the same Download PDF

Info

Publication number
SK134398A3
SK134398A3 SK1343-98A SK134398A SK134398A3 SK 134398 A3 SK134398 A3 SK 134398A3 SK 134398 A SK134398 A SK 134398A SK 134398 A3 SK134398 A3 SK 134398A3
Authority
SK
Slovakia
Prior art keywords
solution
hemoglobin
pyridoxylated
polymerized
less
Prior art date
Application number
SK1343-98A
Other languages
English (en)
Slovak (sk)
Inventor
Richard E Dewoskin
Marc D Doubleday
Original Assignee
Northfield Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Northfield Lab filed Critical Northfield Lab
Publication of SK134398A3 publication Critical patent/SK134398A3/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SK1343-98A 1996-03-28 1997-03-27 Aqueous solution of the pyridoxylated polymerized hemoglobin and method for preparing the same SK134398A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1438996P 1996-03-28 1996-03-28
PCT/US1997/005088 WO1997035883A1 (en) 1996-03-28 1997-03-27 Method and apparatus for preparing an acellular red blood cell substitute

Publications (1)

Publication Number Publication Date
SK134398A3 true SK134398A3 (en) 2001-01-18

Family

ID=21765191

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1343-98A SK134398A3 (en) 1996-03-28 1997-03-27 Aqueous solution of the pyridoxylated polymerized hemoglobin and method for preparing the same

Country Status (26)

Country Link
US (5) US6498141B2 (is)
EP (1) EP0928294B1 (is)
JP (1) JP2000507947A (is)
CN (1) CN1129608C (is)
AP (1) AP1028A (is)
AT (1) ATE241646T1 (is)
AU (1) AU740210B2 (is)
BG (1) BG63919B1 (is)
BR (1) BR9708388A (is)
CA (1) CA2250274C (is)
CZ (1) CZ299357B6 (is)
DE (1) DE69722422T2 (is)
DK (1) DK0928294T3 (is)
ES (1) ES2200177T3 (is)
IL (1) IL126376A (is)
IS (1) IS4854A (is)
NO (1) NO324121B1 (is)
NZ (2) NZ538045A (is)
OA (1) OA10884A (is)
PL (1) PL187923B1 (is)
PT (1) PT928294E (is)
RO (1) RO121089B1 (is)
RU (1) RU2203087C2 (is)
SK (1) SK134398A3 (is)
UA (1) UA64710C2 (is)
WO (1) WO1997035883A1 (is)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ538045A (en) * 1996-03-28 2006-11-30 Northfield Lab Method of transfusion with an acellular red blood cell substitute
KR20030097834A (ko) 2001-04-18 2003-12-31 노쓰필드 라보라토리스, 인코포레이티드 안정화된 헤모글로빈 용액을 저장하기 위한 가요성 용기시스템
DE10220992A1 (de) * 2002-05-11 2003-12-04 Sanguibiotech Ag Verwendung eines oder mehrerer Sauerstoffträger, ausgewählt aus Hämoglobin, Myoglobin und Derivaten hiervon zur Behandlung einer Organfunktionsstörung infolge eines akuten Versorgungsmangels und zur Behandlung/Vermeidung einer Gewebeschädigung infolge einer solchen Störung
MXPA05003340A (es) * 2002-10-03 2005-07-05 Northfield Lab Metodo para tratamiento de pacientes con perdida masiva de sangre.
US7135553B2 (en) * 2003-01-29 2006-11-14 Northfield Laboratories, Inc. Polymerized hemoglobin solutions having reduced amounts of tetramer and method for preparing
SE528214C2 (sv) * 2005-06-23 2006-09-26 Proliff Ab Förfarande för framställning av blodplättslysat
EP1978802A2 (en) * 2006-01-24 2008-10-15 Northfield Laboratories, Inc. Polymerized hemoglobin media and its use in isolation and transplantation of islet cells
US20090004159A1 (en) * 2006-01-24 2009-01-01 The Board Of Trustees Of The University Of Illinoi Polymerized Hemoglobin Media and Its Use in Isolation and Transplantation of Islet Cells
RU2340354C1 (ru) * 2007-06-05 2008-12-10 Общество с ограниченной ответственностью "Геленпол" Кровезаменитель с функцией переноса кислорода
RU2361608C1 (ru) * 2008-03-18 2009-07-20 Общество С Ограниченной Ответственностью "Научно-Производственная Компания "Медбиофарм" Кровезаменитель с функцией переноса кислорода, фармацевтическая композиция (варианты)
AU2018304174A1 (en) * 2017-07-18 2020-02-06 VirTech Bio, Inc. Blood substitutes comprising hemoglobin and methods of making

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4826811A (en) * 1986-06-20 1989-05-02 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5464814A (en) * 1986-06-20 1995-11-07 Northfield Laboratories, Inc. Acellular red blood cell substitute
US5194590A (en) * 1986-06-20 1993-03-16 Northfield Laboratories, Inc. Acellular red blood cell substitute
IL87708A (en) * 1988-09-08 1994-04-12 Technion Inst For Research And Hemoglobin-based blood substitute possessing a colloid oncotic pressure substantially similar to human blood and method for the preparation thereof
SE9001378D0 (sv) * 1990-04-18 1990-04-18 Kabivitrum Ab A method for the preparation of pyridoxylated hemoglobin
TW381022B (en) * 1993-08-16 2000-02-01 Hsia Jen Chang Compositions and methods utilizing nitroxides to avoid oxygen toxicity, particularly in stabilized, polymerized, conjugated, or encapsulated hemoglobin used as a red cell substitute
NZ538045A (en) * 1996-03-28 2006-11-30 Northfield Lab Method of transfusion with an acellular red blood cell substitute
US5998361A (en) * 1996-10-18 1999-12-07 University Of Maryland At Baltimore Polymerized hemoglobin

Also Published As

Publication number Publication date
BG102810A (en) 1999-09-30
NZ538045A (en) 2006-11-30
CA2250274A1 (en) 1997-10-02
EP0928294A1 (en) 1999-07-14
RU2203087C2 (ru) 2003-04-27
ES2200177T3 (es) 2004-03-01
PL187923B1 (pl) 2004-11-30
DK0928294T3 (da) 2003-09-22
US6498141B2 (en) 2002-12-24
US20100197566A1 (en) 2010-08-05
JP2000507947A (ja) 2000-06-27
BR9708388A (pt) 2000-01-04
CA2250274C (en) 2003-09-16
PT928294E (pt) 2003-10-31
DE69722422T2 (de) 2004-05-06
BG63919B1 (bg) 2003-06-30
OA10884A (en) 2001-10-11
AP1028A (en) 2001-11-30
US20020025343A1 (en) 2002-02-28
NO324121B1 (no) 2007-08-27
US20050065067A1 (en) 2005-03-24
US20030191050A1 (en) 2003-10-09
WO1997035883A1 (en) 1997-10-02
IS4854A (is) 1998-09-28
CN1219939A (zh) 1999-06-16
AU2425397A (en) 1997-10-17
DE69722422D1 (de) 2003-07-03
IL126376A (en) 2009-09-22
AU740210B2 (en) 2001-11-01
PL329108A1 (en) 1999-03-15
US7521417B2 (en) 2009-04-21
NO984473L (no) 1998-11-25
CZ310098A3 (cs) 1999-09-15
US20080108555A1 (en) 2008-05-08
AP9801353A0 (en) 1998-09-30
ATE241646T1 (de) 2003-06-15
EP0928294B1 (en) 2003-05-28
IL126376A0 (en) 1999-05-09
NO984473D0 (no) 1998-09-25
CZ299357B6 (cs) 2008-07-02
NZ332067A (en) 2001-03-30
RO121089B1 (ro) 2006-12-29
CN1129608C (zh) 2003-12-03
UA64710C2 (en) 2004-03-15

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