SI9420041A - Positive inotropic and lusitropic pyrroloquinolinone derivatives - Google Patents

Positive inotropic and lusitropic pyrroloquinolinone derivatives Download PDF

Info

Publication number
SI9420041A
SI9420041A SI9420041A SI9420041A SI9420041A SI 9420041 A SI9420041 A SI 9420041A SI 9420041 A SI9420041 A SI 9420041A SI 9420041 A SI9420041 A SI 9420041A SI 9420041 A SI9420041 A SI 9420041A
Authority
SI
Slovenia
Prior art keywords
formula
compounds
compound
optionally substituted
pharmaceutically acceptable
Prior art date
Application number
SI9420041A
Other languages
English (en)
Slovenian (sl)
Inventor
Edgar Jean Eddy Freyne
Margaretha Herman Raeymaekers
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SI9420041A publication Critical patent/SI9420041A/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
SI9420041A 1993-06-21 1994-06-15 Positive inotropic and lusitropic pyrroloquinolinone derivatives SI9420041A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93201771 1993-06-21

Publications (1)

Publication Number Publication Date
SI9420041A true SI9420041A (en) 1996-08-31

Family

ID=8213908

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9420041A SI9420041A (en) 1993-06-21 1994-06-15 Positive inotropic and lusitropic pyrroloquinolinone derivatives

Country Status (29)

Country Link
US (1) US5602134A (lv)
EP (1) EP0707586B1 (lv)
JP (1) JP2812804B2 (lv)
KR (1) KR0181560B1 (lv)
CN (1) CN1043765C (lv)
AT (1) ATE171179T1 (lv)
AU (1) AU679077B2 (lv)
BG (1) BG62171B1 (lv)
BR (1) BR9406899A (lv)
CA (1) CA2163122C (lv)
CZ (1) CZ284350B6 (lv)
DE (1) DE69413398T2 (lv)
FI (1) FI109124B (lv)
HU (1) HU220670B1 (lv)
IL (1) IL110055A (lv)
LT (1) LT3447B (lv)
LV (1) LV11545B (lv)
MY (1) MY110751A (lv)
NO (1) NO305366B1 (lv)
OA (1) OA10202A (lv)
PH (1) PH31308A (lv)
PL (1) PL176783B1 (lv)
RU (1) RU2129554C1 (lv)
SG (1) SG49717A1 (lv)
SI (1) SI9420041A (lv)
SK (1) SK280400B6 (lv)
TW (1) TW593317B (lv)
WO (1) WO1995000512A1 (lv)
ZA (1) ZA944382B (lv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208497B2 (en) 2001-07-02 2007-04-24 Novo Nordisk A/S Substituted piperazines and diazepanes
ES2349118T3 (es) * 2001-09-14 2010-12-28 High Point Pharmaceuticals, Llc Nuevos derivados de aminoazetidina, pirrolidina y piperidina.
US20030186963A1 (en) 2001-09-14 2003-10-02 Dorwald Florencio Zaragoza Substituted piperidines
TWI498115B (zh) * 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
GB0808953D0 (en) * 2008-05-16 2008-06-25 Shire Llc substituted quinazolines
GB0808944D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
RU2457208C2 (ru) * 2009-07-06 2012-07-27 Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО "ПГФА Росздрава") 1H-ПИРРОЛО[3,4-b]ХИНОЛИН-3,9(2H,4H)-ДИОНЫ, ОБЛАДАЮЩИЕ ПРОТИВОТУБЕРКУЛЕЗНОЙ АКТИВНОСТЬЮ, И СПОСОБ ИХ ПОЛУЧЕНИЯ

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775674A (en) 1986-05-23 1988-10-04 Bristol-Myers Company Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
CN1030196C (zh) * 1989-07-07 1995-11-01 詹森药业有限公司 增强收缩力和舒张力的-二氢咪唑并喹唑啉酮衍生物的制备方法
NZ234186A (en) * 1989-07-07 1991-10-25 Janssen Pharmaceutica Nv Imidazo quinazolin-one derivatives and pharmaceutical compositions
US5220023A (en) * 1989-07-18 1993-06-15 Janssen Pharmaceutica N.V. Glycine derivatives
US4943573A (en) 1989-11-01 1990-07-24 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas

Also Published As

Publication number Publication date
JP2812804B2 (ja) 1998-10-22
MY110751A (en) 1999-02-27
LTIP1960A (en) 1995-01-31
ATE171179T1 (de) 1998-10-15
CA2163122C (en) 2005-06-14
TW593317B (en) 2004-06-21
AU7000894A (en) 1995-01-17
NO305366B1 (no) 1999-05-18
BR9406899A (pt) 1996-04-09
JPH09500108A (ja) 1997-01-07
SG49717A1 (en) 1998-06-15
BG62171B1 (bg) 1999-04-30
DE69413398D1 (de) 1998-10-22
AU679077B2 (en) 1997-06-19
US5602134A (en) 1997-02-11
RU2129554C1 (ru) 1999-04-27
BG100209A (bg) 1996-07-31
FI109124B (fi) 2002-05-31
OA10202A (en) 1996-12-18
FI956143A (fi) 1995-12-20
IL110055A (en) 1997-09-30
DE69413398T2 (de) 1999-04-15
EP0707586A1 (en) 1996-04-24
NO955028D0 (no) 1995-12-12
KR0181560B1 (ko) 1999-05-01
CN1125945A (zh) 1996-07-03
SK159695A3 (en) 1997-01-08
CZ284350B6 (cs) 1998-10-14
WO1995000512A1 (en) 1995-01-05
SK280400B6 (sk) 2000-01-18
LT3447B (en) 1995-10-25
ZA944382B (en) 1995-12-20
CA2163122A1 (en) 1995-01-05
HU9501970D0 (en) 1995-09-28
PL176783B1 (pl) 1999-07-30
CN1043765C (zh) 1999-06-23
FI956143A0 (fi) 1995-12-20
LV11545A (lv) 1996-10-20
HUT72090A (en) 1996-03-28
HU220670B1 (hu) 2002-04-29
CZ336695A3 (en) 1996-03-13
NO955028L (no) 1995-12-12
PH31308A (en) 1998-07-06
LV11545B (en) 1997-08-20
IL110055A0 (en) 1994-10-07
EP0707586B1 (en) 1998-09-16
PL312252A1 (en) 1996-04-01

Similar Documents

Publication Publication Date Title
FI92697C (fi) Menetelmä lääkeaineina käyttökelpoisten imidatso/4,5-b/kinolinyylioksialkaanihappoamidien valmistamiseksi
US4898872A (en) Imidazo[4,5-b]pyridyl quinolone cardiac stimulants
US7897607B2 (en) Cyclic compounds
IE901258L (en) Pyrimidine derivatives
US4782055A (en) Imidazopyridine compounds useful in the treatment of ulcers
US4602019A (en) Indeno[1,2-c]pyridazin-3-one derivatives useful as cardiotonic and antihypertensive agents
JP2002523505A (ja) Pde3−及びpde−4抑制作用を有するベンゾナフチリデン−n−オキシド
EP0546102B1 (en) Tropolone derivatives and pharmaceutical composition thereof for preventing and treating ischemic diseases
SI9420041A (en) Positive inotropic and lusitropic pyrroloquinolinone derivatives
CS262690B2 (en) Process for preparing 1-/hydroxystyryl/-5h-2,3-benzodiazepines
JPS6172781A (ja) 新規なイミダゾール基含有3,4‐ジヒドロ‐2(1h)‐ピリドン類および2(1h)‐ピリドン類
US5252567A (en) Diazine derivatives
MXPA94004666A (en) Inotropic and positive lusitropic derivatives of pirroloquinolin
NZ267647A (en) Pyrroloquinolinone derivatives, medicaments thereof and pyrrole intermediates
EP0257918A1 (en) Quinolone cardiac stimulants
CA2081236A1 (en) Amino acid derivatives
JPH02255678A (ja) ピリダジノン誘導体及びその製造方法
JPS61134389A (ja) トリアジノン誘導体および抗潰瘍剤
JPS59205367A (ja) 置換されたインデノ−ピリダジノン化合物

Legal Events

Date Code Title Description
IF Valid on the event date
KO00 Lapse of patent

Effective date: 20090219