IL110055A - POSITIVE INOTROPIC AND LUSITROPIC 6-(SUBSTITUTED ALKOXY)-2, 3-DIHYDROPYRROLO£2,3-b| QUINOLIN-2-ONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

POSITIVE INOTROPIC AND LUSITROPIC 6-(SUBSTITUTED ALKOXY)-2, 3-DIHYDROPYRROLO£2,3-b| QUINOLIN-2-ONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
IL110055A
IL110055A IL110055A IL11005594A IL110055A IL 110055 A IL110055 A IL 110055A IL 110055 A IL110055 A IL 110055A IL 11005594 A IL11005594 A IL 11005594A IL 110055 A IL110055 A IL 110055A
Authority
IL
Israel
Prior art keywords
lusitropic
preparation
pharmaceutical compositions
pct
dihydropyrrolo
Prior art date
Application number
IL110055A
Other languages
English (en)
Other versions
IL110055A0 (en
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Priority to IL120508A priority Critical patent/IL120508A/en
Publication of IL110055A0 publication Critical patent/IL110055A0/xx
Priority to IL12050897A priority patent/IL120508A0/xx
Publication of IL110055A publication Critical patent/IL110055A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
IL110055A 1993-06-21 1994-06-20 POSITIVE INOTROPIC AND LUSITROPIC 6-(SUBSTITUTED ALKOXY)-2, 3-DIHYDROPYRROLO£2,3-b| QUINOLIN-2-ONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IL110055A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL120508A IL120508A (en) 1993-06-21 1994-06-20 History of acid 3-] 2,5-dioxo-3-pyrolinidine (methyl [4-nitro) or amino (phenoxyalkanoic) and alkylcarbamic (
IL12050897A IL120508A0 (en) 1993-06-21 1997-03-24 2, 5-dioxopyrrolidine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93201771 1993-06-21

Publications (2)

Publication Number Publication Date
IL110055A0 IL110055A0 (en) 1994-10-07
IL110055A true IL110055A (en) 1997-09-30

Family

ID=8213908

Family Applications (1)

Application Number Title Priority Date Filing Date
IL110055A IL110055A (en) 1993-06-21 1994-06-20 POSITIVE INOTROPIC AND LUSITROPIC 6-(SUBSTITUTED ALKOXY)-2, 3-DIHYDROPYRROLO£2,3-b| QUINOLIN-2-ONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (29)

Country Link
US (1) US5602134A (lv)
EP (1) EP0707586B1 (lv)
JP (1) JP2812804B2 (lv)
KR (1) KR0181560B1 (lv)
CN (1) CN1043765C (lv)
AT (1) ATE171179T1 (lv)
AU (1) AU679077B2 (lv)
BG (1) BG62171B1 (lv)
BR (1) BR9406899A (lv)
CA (1) CA2163122C (lv)
CZ (1) CZ284350B6 (lv)
DE (1) DE69413398T2 (lv)
FI (1) FI109124B (lv)
HU (1) HU220670B1 (lv)
IL (1) IL110055A (lv)
LT (1) LT3447B (lv)
LV (1) LV11545B (lv)
MY (1) MY110751A (lv)
NO (1) NO305366B1 (lv)
OA (1) OA10202A (lv)
PH (1) PH31308A (lv)
PL (1) PL176783B1 (lv)
RU (1) RU2129554C1 (lv)
SG (1) SG49717A1 (lv)
SI (1) SI9420041A (lv)
SK (1) SK280400B6 (lv)
TW (1) TW593317B (lv)
WO (1) WO1995000512A1 (lv)
ZA (1) ZA944382B (lv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208497B2 (en) 2001-07-02 2007-04-24 Novo Nordisk A/S Substituted piperazines and diazepanes
US20030186963A1 (en) 2001-09-14 2003-10-02 Dorwald Florencio Zaragoza Substituted piperidines
DE60234616D1 (de) * 2001-09-14 2010-01-14 High Point Pharmaceuticals Llc Substituierte piperidinen mit selektiver bindungsfähigkeit zu histamin h3-rezeptoren
TWI498115B (zh) * 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
GB0808944D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
GB0808953D0 (en) * 2008-05-16 2008-06-25 Shire Llc substituted quinazolines
RU2457208C2 (ru) * 2009-07-06 2012-07-27 Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО "ПГФА Росздрава") 1H-ПИРРОЛО[3,4-b]ХИНОЛИН-3,9(2H,4H)-ДИОНЫ, ОБЛАДАЮЩИЕ ПРОТИВОТУБЕРКУЛЕЗНОЙ АКТИВНОСТЬЮ, И СПОСОБ ИХ ПОЛУЧЕНИЯ

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775674A (en) 1986-05-23 1988-10-04 Bristol-Myers Company Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
CN1030196C (zh) * 1989-07-07 1995-11-01 詹森药业有限公司 增强收缩力和舒张力的-二氢咪唑并喹唑啉酮衍生物的制备方法
NZ234186A (en) * 1989-07-07 1991-10-25 Janssen Pharmaceutica Nv Imidazo quinazolin-one derivatives and pharmaceutical compositions
US5220023A (en) * 1989-07-18 1993-06-15 Janssen Pharmaceutica N.V. Glycine derivatives
US4943573A (en) 1989-11-01 1990-07-24 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas

Also Published As

Publication number Publication date
NO955028D0 (no) 1995-12-12
FI956143A0 (fi) 1995-12-20
TW593317B (en) 2004-06-21
AU7000894A (en) 1995-01-17
LTIP1960A (en) 1995-01-31
JPH09500108A (ja) 1997-01-07
RU2129554C1 (ru) 1999-04-27
SK280400B6 (sk) 2000-01-18
JP2812804B2 (ja) 1998-10-22
MY110751A (en) 1999-02-27
OA10202A (en) 1996-12-18
ATE171179T1 (de) 1998-10-15
US5602134A (en) 1997-02-11
PL176783B1 (pl) 1999-07-30
CA2163122C (en) 2005-06-14
KR0181560B1 (ko) 1999-05-01
HU9501970D0 (en) 1995-09-28
CA2163122A1 (en) 1995-01-05
CN1125945A (zh) 1996-07-03
NO955028L (no) 1995-12-12
LV11545A (lv) 1996-10-20
LT3447B (en) 1995-10-25
IL110055A0 (en) 1994-10-07
FI956143A (fi) 1995-12-20
CZ336695A3 (en) 1996-03-13
BG62171B1 (bg) 1999-04-30
EP0707586A1 (en) 1996-04-24
HUT72090A (en) 1996-03-28
DE69413398T2 (de) 1999-04-15
WO1995000512A1 (en) 1995-01-05
AU679077B2 (en) 1997-06-19
FI109124B (fi) 2002-05-31
SI9420041A (en) 1996-08-31
EP0707586B1 (en) 1998-09-16
PL312252A1 (en) 1996-04-01
CN1043765C (zh) 1999-06-23
SK159695A3 (en) 1997-01-08
CZ284350B6 (cs) 1998-10-14
DE69413398D1 (de) 1998-10-22
SG49717A1 (en) 1998-06-15
BG100209A (bg) 1996-07-31
LV11545B (en) 1997-08-20
HU220670B1 (hu) 2002-04-29
ZA944382B (en) 1995-12-20
BR9406899A (pt) 1996-04-09
PH31308A (en) 1998-07-06
NO305366B1 (no) 1999-05-18

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees