ES8609330A1 - Un procedimiento para preparar nuevos derivados de 1,3-dihi-dro-6-1-ciano-1-isopropil-n-fenetil-n-metil-omega-aminoal- quil-7--hidroxi-furo-(3,4-c)-piridina - Google Patents

Un procedimiento para preparar nuevos derivados de 1,3-dihi-dro-6-1-ciano-1-isopropil-n-fenetil-n-metil-omega-aminoal- quil-7--hidroxi-furo-(3,4-c)-piridina

Info

Publication number
ES8609330A1
ES8609330A1 ES548209A ES548209A ES8609330A1 ES 8609330 A1 ES8609330 A1 ES 8609330A1 ES 548209 A ES548209 A ES 548209A ES 548209 A ES548209 A ES 548209A ES 8609330 A1 ES8609330 A1 ES 8609330A1
Authority
ES
Spain
Prior art keywords
furo
methyl
same
pyridine derivatives
phenethylaminoalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES548209A
Other languages
English (en)
Other versions
ES548209A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of ES8609330A1 publication Critical patent/ES8609330A1/es
Publication of ES548209A0 publication Critical patent/ES548209A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Abstract

PREPARACION DE DERIVADOS DE 1,3-DIHIDRO-6-(1-CIANO-1-ISOPROPIL-N-FENETIL-N-METIL-OMEGA-AMINOALQUIL)-7-HIDROXI-FURO-(3,4-C)-PIRIDINA. CONSISTENTE EN HACER REACCIONAR, EN CANTIDADES ESTEQUIOMETRICAS, UN DERIVADO DE 6-(1-CIANO-2-METIL-PROPIL)-7-HIDROXI-FURO-(3,4-C)-PIRIDINA DE FORMULA (II) CON UN CLORURO DE N-METIL-N-FENIL-OMEGA-AMINOALQUILO DE FORMULA (III), EN DIMETILSULFOXIDO COMO DISOLVENTE, ENTRE 15-65JC, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: A1 Y A2, INDEPENDIENTEMENTE, H, RADICAL CARBONADO DE C 1 A 5 Y OTROS; R DE 1 A 3 GRUPOS METOXI; X, H, O CL; Y N, 2, 3, 4 O 5. SE UTILIZAN EN FARMACOLOGIA ACTIVIDAD EN EL CAMPO DEL ANTAGONISMO DEL CA, DE LOS RECEPTORES SEROTONINERGICOS Y DE LA DIURESIS SELECTIVA SUAVE.43
ES548209A 1984-10-27 1985-10-25 Un procedimiento para preparar nuevos derivados de 1,3-dihi-dro-6-1-ciano-1-isopropil-n-fenetil-n-metil-omega-aminoal- quil-7--hidroxi-furo-(3,4-c)-piridina Expired ES8609330A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848427218A GB8427218D0 (en) 1984-10-27 1984-10-27 Pyridine derivatives

Publications (2)

Publication Number Publication Date
ES8609330A1 true ES8609330A1 (es) 1986-08-01
ES548209A0 ES548209A0 (es) 1986-08-01

Family

ID=10568857

Family Applications (1)

Application Number Title Priority Date Filing Date
ES548209A Expired ES8609330A1 (es) 1984-10-27 1985-10-25 Un procedimiento para preparar nuevos derivados de 1,3-dihi-dro-6-1-ciano-1-isopropil-n-fenetil-n-metil-omega-aminoal- quil-7--hidroxi-furo-(3,4-c)-piridina

Country Status (25)

Country Link
US (1) US4659719A (es)
JP (1) JPS61289090A (es)
AR (1) AR242212A1 (es)
AT (1) AT394558B (es)
BE (1) BE903438A (es)
CA (1) CA1300151C (es)
CH (1) CH666689A5 (es)
DE (1) DE3538063A1 (es)
DK (1) DK160049C (es)
DZ (1) DZ850A1 (es)
ES (1) ES8609330A1 (es)
FI (1) FI82248C (es)
FR (2) FR2572285B1 (es)
GB (2) GB8427218D0 (es)
HK (1) HK6289A (es)
IE (1) IE59475B1 (es)
IT (1) IT1190413B (es)
LU (1) LU86136A1 (es)
MA (1) MA20558A1 (es)
NL (1) NL8502899A (es)
NO (1) NO162191C (es)
OA (1) OA08128A (es)
PT (1) PT81365B (es)
SE (1) SE463154B (es)
ZA (1) ZA858004B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8426738D0 (en) * 1984-10-23 1984-11-28 Scras Pyridine derivatives
DE3642331A1 (de) * 1986-12-11 1988-06-23 Basf Ag Basisch substituierte phenylacetonitrile, ihre herstellung und diese enthaltende arzneimittel
GB8808001D0 (en) * 1988-04-06 1988-05-05 Scras Stereospecific preparative process for furol(3,4-c)pyridine derivatives
US5130252A (en) * 1990-05-14 1992-07-14 Synthetech, Inc. Resolution of furopyridine enantiomers and synthetic precursors thereof
US6475493B1 (en) 1999-09-02 2002-11-05 Norstrum Pharmaceuticals, Inc. Controlled release pellet formulation
US20070095037A1 (en) * 2007-01-18 2007-05-03 Mclamb Samuel B Iii Supplementary air filter and retainer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1551268A (es) * 1967-12-07 1968-12-27
ZA786269B (en) * 1977-11-25 1979-10-31 Scras New pyridine derivative,its preparation and use
IN156817B (es) * 1981-02-10 1985-11-09 Scras
IN160104B (es) * 1983-04-05 1987-06-27 Scras
GB2137618B (en) * 1983-04-05 1986-05-08 Scras Furo-(3,4-c)-pyridine derivatives
GB8402740D0 (en) * 1984-02-02 1984-03-07 Scras Furo-(3 4-c)-pyridine derivatives
GB8422029D0 (en) * 1984-08-31 1984-10-03 Scras 6-substituted-furo-(3 4-c)-pyridine derivatives

Also Published As

Publication number Publication date
MA20558A1 (fr) 1986-07-01
FI82248B (fi) 1990-10-31
SE8504826D0 (sv) 1985-10-16
FR2572285A1 (fr) 1986-05-02
NO162191B (no) 1989-08-14
DK160049B (da) 1991-01-21
GB8427218D0 (en) 1984-12-05
AR242212A1 (es) 1993-03-31
HK6289A (en) 1989-01-27
LU86136A1 (fr) 1986-03-24
NO162191C (no) 1989-11-29
FR2572405A1 (fr) 1986-05-02
GB2166136B (en) 1987-11-18
IT1190413B (it) 1988-02-16
IE852645L (en) 1986-04-27
FI854180L (fi) 1986-04-28
DE3538063C2 (es) 1992-10-15
JPS61289090A (ja) 1986-12-19
NO854277L (no) 1986-04-28
JPH0344075B2 (es) 1991-07-04
OA08128A (fr) 1987-03-31
NL8502899A (nl) 1986-05-16
PT81365B (pt) 1987-11-11
ATA310385A (de) 1991-10-15
FR2572285B1 (fr) 1988-12-16
FR2572405B1 (fr) 1988-12-16
PT81365A (en) 1985-11-01
DK490385D0 (da) 1985-10-25
GB2166136A (en) 1986-04-30
IE59475B1 (en) 1994-03-09
SE463154B (sv) 1990-10-15
IT8522612A0 (it) 1985-10-25
DK490385A (da) 1986-04-28
CA1300151C (en) 1992-05-05
SE8504826L (sv) 1986-04-28
FI854180A0 (fi) 1985-10-25
DK160049C (da) 1991-06-17
US4659719A (en) 1987-04-21
ZA858004B (en) 1986-05-28
GB8525939D0 (en) 1985-11-27
DZ850A1 (fr) 2004-09-13
FI82248C (fi) 1991-02-11
CH666689A5 (fr) 1988-08-15
BE903438A (fr) 1986-04-14
DE3538063A1 (de) 1986-04-30
AT394558B (de) 1992-05-11
ES548209A0 (es) 1986-08-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000223