SI9111318A - Acetamide derivatives - Google Patents

Acetamide derivatives Download PDF

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Publication number
SI9111318A
SI9111318A SI9111318A SI9111318A SI9111318A SI 9111318 A SI9111318 A SI 9111318A SI 9111318 A SI9111318 A SI 9111318A SI 9111318 A SI9111318 A SI 9111318A SI 9111318 A SI9111318 A SI 9111318A
Authority
SI
Slovenia
Prior art keywords
acetyl
methoxy
hydrogen
formula
nitromethane
Prior art date
Application number
SI9111318A
Other languages
English (en)
Slovenian (sl)
Inventor
David Robert Brittain
Steven Paul Brown
Anthony Loren Cooper
Jethro Lawrence Longridge
Jeffrey James Morris
John Preston
Linda Slater
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10680064&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI9111318(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ici Plc filed Critical Ici Plc
Publication of SI9111318A publication Critical patent/SI9111318A/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
    • C07C317/40—Y being a hydrogen or a carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C313/02—Sulfinic acids; Derivatives thereof
    • C07C313/04—Sulfinic acids; Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40—Y being a hydrogen or a carbon atom
    • C07C323/41—Y being a hydrogen or an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/06—One of the condensed rings being a six-membered aromatic ring the other ring being four-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI9111318A 1990-08-02 1991-07-29 Acetamide derivatives SI9111318A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909016978A GB9016978D0 (en) 1990-08-02 1990-08-02 Acetamide derivatives
YU131891A YU131891A (sh) 1990-08-02 1991-07-29 Derivati acetamida, postupak za njihovo dobijanje i farmaceutski preparati koji ih sadrže

Publications (1)

Publication Number Publication Date
SI9111318A true SI9111318A (en) 1997-10-31

Family

ID=10680064

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9111318A SI9111318A (en) 1990-08-02 1991-07-29 Acetamide derivatives

Country Status (33)

Country Link
US (2) US5270342A (cs)
EP (1) EP0469887B1 (cs)
JP (1) JP2930452B2 (cs)
KR (1) KR920004342A (cs)
CN (1) CN1036389C (cs)
AP (1) AP261A (cs)
AT (1) ATE115560T1 (cs)
AU (1) AU646273B2 (cs)
BG (1) BG60316B2 (cs)
CA (1) CA2048325A1 (cs)
CZ (1) CZ280642B6 (cs)
DE (1) DE69105856T2 (cs)
DK (1) DK0469887T3 (cs)
ES (1) ES2067874T3 (cs)
FI (1) FI913706A7 (cs)
GB (2) GB9016978D0 (cs)
HK (1) HK1000965A1 (cs)
HR (1) HRP931326B1 (cs)
HU (2) HU210057B (cs)
IE (1) IE65870B1 (cs)
IL (1) IL98908A (cs)
JO (1) JO1696B1 (cs)
MY (1) MY109594A (cs)
NO (1) NO175528C (cs)
NZ (1) NZ239124A (cs)
PH (1) PH31572A (cs)
PL (2) PL166392B1 (cs)
PT (1) PT98529B (cs)
RO (1) RO109645B1 (cs)
RU (1) RU2068409C1 (cs)
SI (1) SI9111318A (cs)
YU (1) YU131891A (cs)
ZA (1) ZA915783B (cs)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9016984D0 (en) * 1990-08-02 1990-09-19 Ici Plc Aniline derivatives
GB9016978D0 (en) * 1990-08-02 1990-09-19 Ici Plc Acetamide derivatives
KR0147963B1 (ko) * 1995-01-10 1998-08-17 강박광 엔-아릴알킬페닐아세트아미드 유도체와 그의 제조방법
FR2757509B1 (fr) 1996-12-23 1999-03-26 Lipha Nouveaux derives de sulfonamides et sulfonylurees, leurs preparations et medicaments les contenant
ZA983170B (en) * 1997-04-15 1999-10-15 Csir Pharmaceutical compositions having appetite suppressant activity.
US5932765A (en) * 1997-05-23 1999-08-03 Merck Patent Gesellschaft Mit Nitromethyl ketones, process for preparing them and compositions containing them
GB9714274D0 (en) 1997-07-08 1997-09-10 Zeneca Ltd Pharmaceutical composition
RU2203665C2 (ru) * 1997-10-20 2003-05-10 Дайниппон Фармасьютикал Ко., Лтд. Быстрорастворяющаяся фармацевтическая композиция
EP1520582A3 (en) 1998-02-02 2009-07-01 Trustees Of Tufts College Use of dipeptidylpetidase inhibitors to regulate glucose metabolism
SI0974356T1 (en) * 1998-07-15 2003-12-31 Merck Sante Tablets comprising a combination of metformin and glibenclamide
GB2355657B (en) * 1999-10-27 2004-07-28 Phytopharm Plc Inhibitors Of Gastric Acid Secretion
GB2363985B (en) 2000-06-30 2004-09-29 Phytopharm Plc Extracts,compounds & pharmaceutical compositions having anti-diabetic activity and their use
BR0115776A (pt) 2000-11-30 2004-01-13 Pfizer Prod Inc Combinações de agonistas de gaba e inibidores da aldose redutase
RU2191012C1 (ru) * 2001-06-20 2002-10-20 Научно-исследовательский испытательный центр (медико-биологической защиты) Государственного научно-исследовательского испытательного института военной медицины МО РФ Глазные капли для лечения эндотелиально-эпителиальной дистрофии роговицы
US20110092566A1 (en) * 2004-11-19 2011-04-21 Srivastava Satish K Treatment of cancer with aldose reductase inhibitors
AU2006241673B2 (en) * 2005-04-28 2011-02-24 Daiichi Sankyo Company, Limited Method for producing hydrazone derivatives
US7671221B2 (en) * 2005-12-28 2010-03-02 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
NZ569327A (en) * 2005-12-28 2011-09-30 Vertex Pharma 1-(benzo [d] [1,3] dioxol-5-yl) -n- (phenyl) cyclopropane- carboxamide derivatives and related compounds as modulators of ATP-binding cassette transporters for the treatment of cystic fibrosis
JP2010520913A (ja) 2007-03-12 2010-06-17 サズセ アーペーエス ルイボスの抗糖尿病性抽出物
EP2848252A3 (en) 2007-03-23 2015-06-17 The Board of Regents of the University of Texas System Aldose reductase inhibitors for use in treating uveitis
FR2914188B1 (fr) * 2007-03-28 2012-06-22 Trophos Nouvelle composition a base d'oxime de cholest-4-en-3-one
US20090270490A1 (en) * 2008-04-24 2009-10-29 The Board Of Regents Of The University Of Texas System Methods involving aldose reductase inhibition
WO2012088525A2 (en) 2010-12-23 2012-06-28 The Board Of Regents Of The University Of Texas System Methods for treating copd
US12090142B2 (en) 2018-02-22 2024-09-17 Board Of Regents, The University Of Texas System Combination therapy for the treatment of cancer

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
GB1229653A (cs) * 1968-03-14 1971-04-28
US3882247A (en) * 1972-04-21 1975-05-06 Du Pont Fungicidal nitro organic sulfur compounds
SU479761A1 (ru) * 1973-07-18 1975-08-05 Институт Органической Химии Им. Н.Д.Зелинского Ан Ссср Способ получени -динитроалкилсульфонов
US4053633A (en) * 1976-06-24 1977-10-11 The Dow Chemical Company Aryl dibromonitromethyl sulfones
US4058633A (en) * 1976-09-15 1977-11-15 Fairmont Foods Company Meat product, and process for preparing same
FR2432316A1 (fr) * 1978-08-02 1980-02-29 Choay Sa Nouveaux medicaments contenant, a titre de substance active, des composes de type benzenesulfone, nouveaux composes de ce type et procede pour leur preparation
US4670470A (en) * 1979-08-15 1987-06-02 Merck & Co., Inc. Allylsulfoxide enzyme inhibitors
US4309554A (en) * 1980-04-28 1982-01-05 The Dow Chemical Company 3-(2-Thiophenesulfonyl)-2-halopropanenitriles
JPS5740478A (en) * 1980-08-22 1982-03-06 Ono Pharmaceut Co Ltd Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative
DE3326635A1 (de) * 1983-07-23 1985-01-31 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von monomethylsubstituierten methylen-verbindungen
WO1985003571A1 (en) * 1984-02-01 1985-08-15 Hulette William C Clinical analysis systems and methods
EP0252640B1 (en) * 1986-06-30 1991-03-06 Merck & Co. Inc. Alkanesulfonamides as antiglaucoma agents
GB8718619D0 (en) * 1987-08-06 1987-09-09 Ici Plc Pharmaceutical compositions
GB8810203D0 (en) * 1988-04-29 1988-06-02 Ici Plc Heterocyclic compounds
IE63463B1 (en) * 1989-02-06 1995-04-19 Zeneca Ltd Phenylsulphone derivatives
GB9016978D0 (en) * 1990-08-02 1990-09-19 Ici Plc Acetamide derivatives

Also Published As

Publication number Publication date
CZ280642B6 (cs) 1996-03-13
EP0469887A1 (en) 1992-02-05
IE912529A1 (en) 1992-02-12
NO913008L (no) 1992-02-03
HU912482D0 (en) 1991-12-30
GB2247678A (en) 1992-03-11
PL168026B1 (pl) 1995-12-30
GB2247678B (en) 1994-07-27
PL291312A1 (en) 1992-09-21
HRP931326B1 (en) 1998-06-30
JO1696B1 (en) 1992-12-15
RU2068409C1 (ru) 1996-10-27
GB9016978D0 (en) 1990-09-19
NO175528C (no) 1994-10-26
MY109594A (en) 1997-03-31
ES2067874T3 (es) 1995-04-01
AU8123391A (en) 1992-02-06
CN1036389C (zh) 1997-11-12
IE65870B1 (en) 1995-11-29
FI913706A7 (fi) 1992-02-03
HU210883A9 (en) 1995-09-28
FI913706A0 (fi) 1991-08-02
US5430060A (en) 1995-07-04
NO913008D0 (no) 1991-08-01
ZA915783B (en) 1992-05-27
PT98529A (pt) 1992-06-30
NZ239124A (en) 1994-04-27
NO175528B (no) 1994-07-18
CA2048325A1 (en) 1992-02-03
YU131891A (sh) 1994-06-10
IL98908A0 (en) 1992-07-15
KR920004342A (ko) 1992-03-27
CS232791A3 (en) 1992-03-18
CN1059517A (zh) 1992-03-18
BG60316B2 (bg) 1994-07-25
IL98908A (en) 1995-03-30
AP9100306A0 (en) 1991-07-31
GB9115254D0 (en) 1991-08-28
PL166392B1 (pl) 1995-05-31
DE69105856T2 (de) 1995-05-11
DE69105856D1 (de) 1995-01-26
JP2930452B2 (ja) 1999-08-03
PT98529B (pt) 1999-01-29
RO109645B1 (ro) 1995-04-28
HRP931326A2 (en) 1996-04-30
US5270342A (en) 1993-12-14
HUT59088A (en) 1992-04-28
EP0469887B1 (en) 1994-12-14
PH31572A (en) 1998-11-03
JPH04234356A (ja) 1992-08-24
HK1000965A1 (en) 1998-05-15
HU210057B (en) 1995-01-30
ATE115560T1 (de) 1994-12-15
AU646273B2 (en) 1994-02-17
DK0469887T3 (da) 1995-04-03
AP261A (en) 1993-06-03

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