SI2158316T1 - Genska ekspresija in bolečina - Google Patents

Genska ekspresija in bolečina

Info

Publication number
SI2158316T1
SI2158316T1 SI200831461T SI200831461T SI2158316T1 SI 2158316 T1 SI2158316 T1 SI 2158316T1 SI 200831461 T SI200831461 T SI 200831461T SI 200831461 T SI200831461 T SI 200831461T SI 2158316 T1 SI2158316 T1 SI 2158316T1
Authority
SI
Slovenia
Prior art keywords
pain
gene expression
gene
expression
Prior art date
Application number
SI200831461T
Other languages
English (en)
Slovenian (sl)
Inventor
Julien Mamet
Original Assignee
Adynxx Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adynxx Inc. filed Critical Adynxx Inc.
Publication of SI2158316T1 publication Critical patent/SI2158316T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/13—Decoys
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
SI200831461T 2007-05-11 2008-05-12 Genska ekspresija in bolečina SI2158316T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91758307P 2007-05-11 2007-05-11
EP08755344.2A EP2158316B1 (en) 2007-05-11 2008-05-12 Gene expression and pain
PCT/US2008/063471 WO2008141308A2 (en) 2007-05-11 2008-05-12 Gene expression and pain

Publications (1)

Publication Number Publication Date
SI2158316T1 true SI2158316T1 (sl) 2015-08-31

Family

ID=40002879

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200831461T SI2158316T1 (sl) 2007-05-11 2008-05-12 Genska ekspresija in bolečina

Country Status (13)

Country Link
US (5) US7943591B2 (cg-RX-API-DMAC7.html)
EP (3) EP2158316B1 (cg-RX-API-DMAC7.html)
JP (5) JP5646320B2 (cg-RX-API-DMAC7.html)
AU (1) AU2008251320B2 (cg-RX-API-DMAC7.html)
CA (1) CA2723672C (cg-RX-API-DMAC7.html)
DK (1) DK2158316T3 (cg-RX-API-DMAC7.html)
ES (2) ES2619314T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20150759T1 (cg-RX-API-DMAC7.html)
HU (1) HUE025701T2 (cg-RX-API-DMAC7.html)
PL (1) PL2158316T3 (cg-RX-API-DMAC7.html)
PT (1) PT2158316E (cg-RX-API-DMAC7.html)
SI (1) SI2158316T1 (cg-RX-API-DMAC7.html)
WO (1) WO2008141308A2 (cg-RX-API-DMAC7.html)

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HRP20150759T1 (hr) * 2007-05-11 2015-08-14 Adynxx, Inc. Ekspresija gena i bolovi
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ES2626488T3 (es) 2011-07-19 2017-07-25 Wave Life Sciences Pte. Ltd. Procedimientos para la síntesis de ácidos nucleicos funcionalizados
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PT2846839T (pt) 2012-05-10 2019-05-29 Adynxx Inc Formulações para a administração de ingredientes ativos
ES2940887T3 (es) 2012-07-13 2023-05-12 Wave Life Sciences Ltd Método de preparación de oligonucleótidos quirales
BR112015000723A2 (pt) 2012-07-13 2017-06-27 Shin Nippon Biomedical Laboratories Ltd adjuvante de ácido nucléico quiral
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JPWO2015108048A1 (ja) 2014-01-15 2017-03-23 株式会社新日本科学 抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤
WO2015108047A1 (ja) 2014-01-15 2015-07-23 株式会社新日本科学 免疫誘導活性を有するキラル核酸アジュバンド及び免疫誘導活性剤
CN113278617A (zh) 2014-01-16 2021-08-20 波涛生命科学有限公司 手性设计
BR112017002629A2 (pt) 2014-08-15 2018-02-20 Adynxx, Inc. decoys de oligonucleotídeo para o tratamento de dor
JP6993230B2 (ja) * 2015-09-09 2022-01-13 アンジェス株式会社 キメラデコイ
WO2017151644A1 (en) * 2016-02-29 2017-09-08 Adynxx, Inc. Compositions and methods for pain amelioration via modification of gene expression
WO2024044770A1 (en) * 2022-08-26 2024-02-29 Core Biotherapeutics, Inc. Oligonucleotides for the treatment of breast cancer

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Also Published As

Publication number Publication date
PT2158316E (pt) 2015-07-20
DK2158316T3 (en) 2015-07-20
EP2158316B1 (en) 2015-04-15
US8093225B2 (en) 2012-01-10
US10041069B2 (en) 2018-08-07
EP2818550A1 (en) 2014-12-31
EP3199635B1 (en) 2019-02-06
JP5646320B2 (ja) 2014-12-24
US20160222382A1 (en) 2016-08-04
US20080300209A1 (en) 2008-12-04
US9290762B2 (en) 2016-03-22
JP2014198053A (ja) 2014-10-23
JP2016014070A (ja) 2016-01-28
JP2017148074A (ja) 2017-08-31
EP3199635A1 (en) 2017-08-02
US7943591B2 (en) 2011-05-17
JP2010526541A (ja) 2010-08-05
ES2542511T3 (es) 2015-08-06
CA2723672C (en) 2019-09-03
EP2158316A4 (en) 2011-11-09
JP6082796B2 (ja) 2017-02-15
US20140343132A1 (en) 2014-11-20
EP2818550B1 (en) 2016-12-28
ES2619314T3 (es) 2017-06-26
CA2723672A1 (en) 2008-11-20
HUE025701T2 (en) 2016-04-28
WO2008141308A3 (en) 2009-03-05
US20110166212A1 (en) 2011-07-07
HRP20150759T1 (hr) 2015-08-14
EP2158316A2 (en) 2010-03-03
WO2008141308A2 (en) 2008-11-20
JP5890869B2 (ja) 2016-03-22
AU2008251320A1 (en) 2008-11-20
AU2008251320B2 (en) 2013-12-19
JP6306075B2 (ja) 2018-04-04
JP2016117775A (ja) 2016-06-30
HK1205530A1 (en) 2015-12-18
PL2158316T3 (pl) 2015-10-30
US8741864B2 (en) 2014-06-03
US20120232131A1 (en) 2012-09-13

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