JP5646320B2 - 遺伝子発現と疼痛 - Google Patents

遺伝子発現と疼痛 Download PDF

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Publication number
JP5646320B2
JP5646320B2 JP2010507728A JP2010507728A JP5646320B2 JP 5646320 B2 JP5646320 B2 JP 5646320B2 JP 2010507728 A JP2010507728 A JP 2010507728A JP 2010507728 A JP2010507728 A JP 2010507728A JP 5646320 B2 JP5646320 B2 JP 5646320B2
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nucleotide
seq
oligonucleotide
sequence
certain embodiments
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Japanese (ja)
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JP2010526541A5 (cg-RX-API-DMAC7.html
JP2010526541A (ja
Inventor
ジュリアン マメ，
ジュリアン マメ，
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アダイニクス， インコーポレイテッド
アダイニクス， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/13—Decoys
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
JP2010507728A 2007-05-11 2008-05-12 遺伝子発現と疼痛 Expired - Fee Related JP5646320B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91758307P 2007-05-11 2007-05-11
US60/917,583 2007-05-11
PCT/US2008/063471 WO2008141308A2 (en) 2007-05-11 2008-05-12 Gene expression and pain

Related Child Applications (1)

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JP2014149516A Division JP5890869B2 (ja) 2007-05-11 2014-07-23 遺伝子発現と疼痛

Publications (3)

Publication Number Publication Date
JP2010526541A JP2010526541A (ja) 2010-08-05
JP2010526541A5 JP2010526541A5 (cg-RX-API-DMAC7.html) 2012-04-05
JP5646320B2 true JP5646320B2 (ja) 2014-12-24

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JP2010507728A Expired - Fee Related JP5646320B2 (ja) 2007-05-11 2008-05-12 遺伝子発現と疼痛
JP2014149516A Expired - Fee Related JP5890869B2 (ja) 2007-05-11 2014-07-23 遺伝子発現と疼痛
JP2015207655A Expired - Fee Related JP6082796B2 (ja) 2007-05-11 2015-10-22 遺伝子発現と疼痛
JP2016064037A Expired - Fee Related JP6306075B2 (ja) 2007-05-11 2016-03-28 遺伝子発現と疼痛
JP2017106521A Pending JP2017148074A (ja) 2007-05-11 2017-05-30 遺伝子発現と疼痛

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JP2014149516A Expired - Fee Related JP5890869B2 (ja) 2007-05-11 2014-07-23 遺伝子発現と疼痛
JP2015207655A Expired - Fee Related JP6082796B2 (ja) 2007-05-11 2015-10-22 遺伝子発現と疼痛
JP2016064037A Expired - Fee Related JP6306075B2 (ja) 2007-05-11 2016-03-28 遺伝子発現と疼痛
JP2017106521A Pending JP2017148074A (ja) 2007-05-11 2017-05-30 遺伝子発現と疼痛

Country Status (13)

Country Link
US (5) US7943591B2 (cg-RX-API-DMAC7.html)
EP (3) EP2818550B1 (cg-RX-API-DMAC7.html)
JP (5) JP5646320B2 (cg-RX-API-DMAC7.html)
AU (1) AU2008251320B2 (cg-RX-API-DMAC7.html)
CA (1) CA2723672C (cg-RX-API-DMAC7.html)
DK (1) DK2158316T3 (cg-RX-API-DMAC7.html)
ES (2) ES2542511T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20150759T1 (cg-RX-API-DMAC7.html)
HU (1) HUE025701T2 (cg-RX-API-DMAC7.html)
PL (1) PL2158316T3 (cg-RX-API-DMAC7.html)
PT (1) PT2158316E (cg-RX-API-DMAC7.html)
SI (1) SI2158316T1 (cg-RX-API-DMAC7.html)
WO (1) WO2008141308A2 (cg-RX-API-DMAC7.html)

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SI2158316T1 (sl) 2015-08-31
CA2723672A1 (en) 2008-11-20
HK1205530A1 (en) 2015-12-18
EP2818550B1 (en) 2016-12-28
US8741864B2 (en) 2014-06-03
US20080300209A1 (en) 2008-12-04
JP2014198053A (ja) 2014-10-23
AU2008251320A1 (en) 2008-11-20
PT2158316E (pt) 2015-07-20
US9290762B2 (en) 2016-03-22
ES2619314T3 (es) 2017-06-26
PL2158316T3 (pl) 2015-10-30
JP2016117775A (ja) 2016-06-30
ES2542511T3 (es) 2015-08-06
JP2017148074A (ja) 2017-08-31
EP3199635B1 (en) 2019-02-06
US8093225B2 (en) 2012-01-10
US10041069B2 (en) 2018-08-07
EP3199635A1 (en) 2017-08-02
HRP20150759T1 (hr) 2015-08-14
JP5890869B2 (ja) 2016-03-22
EP2158316A4 (en) 2011-11-09
DK2158316T3 (en) 2015-07-20
AU2008251320B2 (en) 2013-12-19
EP2158316B1 (en) 2015-04-15
JP6306075B2 (ja) 2018-04-04
US20110166212A1 (en) 2011-07-07
EP2158316A2 (en) 2010-03-03
HUE025701T2 (en) 2016-04-28
JP6082796B2 (ja) 2017-02-15
US7943591B2 (en) 2011-05-17
WO2008141308A3 (en) 2009-03-05
WO2008141308A2 (en) 2008-11-20
EP2818550A1 (en) 2014-12-31
US20120232131A1 (en) 2012-09-13
US20140343132A1 (en) 2014-11-20
CA2723672C (en) 2019-09-03
US20160222382A1 (en) 2016-08-04
JP2010526541A (ja) 2010-08-05
JP2016014070A (ja) 2016-01-28

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