ATE295367T1 - Doppelsträngiges oligonukleotid und karzinostatisches mittel das dieses als aktiven inhaltsstoff enthält - Google Patents

Doppelsträngiges oligonukleotid und karzinostatisches mittel das dieses als aktiven inhaltsstoff enthält

Info

Publication number
ATE295367T1
ATE295367T1 AT95938023T AT95938023T ATE295367T1 AT E295367 T1 ATE295367 T1 AT E295367T1 AT 95938023 T AT95938023 T AT 95938023T AT 95938023 T AT95938023 T AT 95938023T AT E295367 T1 ATE295367 T1 AT E295367T1
Authority
AT
Austria
Prior art keywords
active ingredient
stranded oligonucleotide
double stranded
agent containing
containing same
Prior art date
Application number
AT95938023T
Other languages
English (en)
Inventor
Ken-Ichi Matsuo
Yoshikazu Sugimoto
Kenji Suzuki
Keisuke Ishida
Yuji Yamada
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE295367T1 publication Critical patent/ATE295367T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/13—Decoys

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT95938023T 1994-11-17 1995-11-16 Doppelsträngiges oligonukleotid und karzinostatisches mittel das dieses als aktiven inhaltsstoff enthält ATE295367T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28306594 1994-11-17
PCT/JP1995/002348 WO1996016074A1 (fr) 1994-11-17 1995-11-16 Oligonucleotide bicatenaire et agent carcinostatique le contenant en tant que constituant actif

Publications (1)

Publication Number Publication Date
ATE295367T1 true ATE295367T1 (de) 2005-05-15

Family

ID=17660755

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95938023T ATE295367T1 (de) 1994-11-17 1995-11-16 Doppelsträngiges oligonukleotid und karzinostatisches mittel das dieses als aktiven inhaltsstoff enthält

Country Status (7)

Country Link
US (1) US6034234A (de)
EP (1) EP0733640B1 (de)
JP (1) JP3392143B2 (de)
AT (1) ATE295367T1 (de)
AU (1) AU3881095A (de)
DE (1) DE69534197T2 (de)
WO (1) WO1996016074A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050164240A1 (en) * 2003-10-06 2005-07-28 Corgentech, Inc. E2F oligonucleotide decoy molecules
US7482158B2 (en) * 2004-07-01 2009-01-27 Mathison Brian H Composite polynucleic acid therapeutics
CA2583576A1 (en) 2004-10-22 2006-04-27 Anges Mg, Inc. Chimera (double) decoy
JPWO2006132204A1 (ja) 2005-06-06 2009-01-08 アンジェスＭｇ株式会社 転写因子デコイ
EP1978096A1 (de) * 2005-12-22 2008-10-08 Genomidea Inc Neues oligonukleotid und dieses umfassender nf-kappa-b-köder
US7943591B2 (en) 2007-05-11 2011-05-17 Adynxx, Inc. Gene expression and pain
EP2266626B1 (de) 2008-03-28 2014-06-18 AnGesMG, Inc. Zusammensetzung zur topischen anwendung mit einem transkriptionsfaktor-decoy als wirkstoff
ES2724851T3 (es) 2012-05-10 2019-09-16 Adynxx Inc Formulaciones para el suministro de principios activos
EP3180434B1 (de) 2014-08-15 2019-07-17 Adynxx, Inc. Oligonukleotidköder zur behandlung von schmerz
WO2017068790A1 (ja) * 2015-10-23 2017-04-27 レナセラピューティクス株式会社 核酸複合体

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06509704A (ja) * 1991-04-18 1994-11-02 ザ　ソールク　インスチチュート　フォア　バイオロジカル　スタディズ 特定ｄｎａ配列に選択的に結合する蛋白質に対する偽構築体として有用なオリゴデオキシヌクレオチドおよびオリゴヌクレオチド
NZ246432A (en) * 1991-12-16 1996-06-25 Genentech Inc Fibrin-specific t-pa with a point mutation at position 276, vector cell cultures
US5759803A (en) * 1992-05-13 1998-06-02 Dana-Farber Cancer Institute Recombinant retinoblastoma-associated protein 1 (E2F-1) polypeptides and cDNA
US5585479A (en) * 1992-07-24 1996-12-17 The United States Of America As Represented By The Secretary Of The Navy Antisense oligonucleotides directed against human ELAM-I RNA
US5859226A (en) * 1993-07-29 1999-01-12 Regents Of The University Of California, The Polynucleotide decoys that inhibit MHC-II expression and uses thereof
US5473056A (en) * 1993-10-13 1995-12-05 Merck & Co., Inc. E2F-2, a novel mammalian transcription factor
EP1340505A3 (de) * 1993-10-29 2004-07-14 The Brigham And Women's Hospital, Inc. Therapeutische Verwendung von cis-Element-Fallen in vivo
WO1995024223A1 (en) * 1994-03-08 1995-09-14 Thomas Jefferson University Inhibition of cell proliferation by e2f-1 antisense oligonucleotides
US5563036A (en) * 1994-04-29 1996-10-08 Tularik, Inc. Transcription factor-DNA binding assay
US5496831A (en) * 1994-05-13 1996-03-05 The General Hospital Corporation Inhibition of insulin-induced adiposis

Also Published As

Publication number Publication date
EP0733640A4 (de) 1999-11-24
AU3881095A (en) 1996-06-17
DE69534197T2 (de) 2006-02-16
DE69534197D1 (de) 2005-06-16
JP3392143B2 (ja) 2003-03-31
EP0733640A1 (de) 1996-09-25
US6034234A (en) 2000-03-07
WO1996016074A1 (fr) 1996-05-30
EP0733640B1 (de) 2005-05-11

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