SI1531805T1 - Sestavek brez askorbinske kisline vsebujoč inhibitor absorpcije holesterola, inhibitor HMG-CoA reduktaze in sredstvo za stabiliziranje - Google Patents

Sestavek brez askorbinske kisline vsebujoč inhibitor absorpcije holesterola, inhibitor HMG-CoA reduktaze in sredstvo za stabiliziranje

Info

Publication number
SI1531805T1
SI1531805T1 SI200331222T SI200331222T SI1531805T1 SI 1531805 T1 SI1531805 T1 SI 1531805T1 SI 200331222 T SI200331222 T SI 200331222T SI 200331222 T SI200331222 T SI 200331222T SI 1531805 T1 SI1531805 T1 SI 1531805T1
Authority
SI
Slovenia
Prior art keywords
inhibitor
hmg
ascorbic acid
stabilizing agent
coa reductase
Prior art date
Application number
SI200331222T
Other languages
English (en)
Inventor
William D Moore
Shaun Fitzpatrick
Christian Seiler
Robert Saklatvala
Catherine R Petts
Wing-Kee Philip Cho
Original Assignee
Merck Sharp & Dohme
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31188454&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1531805(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme, Schering Corp filed Critical Merck Sharp & Dohme
Publication of SI1531805T1 publication Critical patent/SI1531805T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
SI200331222T 2002-07-26 2003-07-22 Sestavek brez askorbinske kisline vsebujoč inhibitor absorpcije holesterola, inhibitor HMG-CoA reduktaze in sredstvo za stabiliziranje SI1531805T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39869102P 2002-07-26 2002-07-26
EP03771709A EP1531805B1 (en) 2002-07-26 2003-07-22 Composition devoid of ascorbic acid comprising a cholesterol absorption inhibitor, an hmg-coa reductase inhibitor and a stabilizing agent
PCT/US2003/022889 WO2004010993A1 (en) 2002-07-26 2003-07-22 Composition comprising a cholesterol absorption inhibitor, an hmg-coa reductase inhibitor and a stabilizing agent

Publications (1)

Publication Number Publication Date
SI1531805T1 true SI1531805T1 (sl) 2008-08-31

Family

ID=31188454

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200331222T SI1531805T1 (sl) 2002-07-26 2003-07-22 Sestavek brez askorbinske kisline vsebujoč inhibitor absorpcije holesterola, inhibitor HMG-CoA reduktaze in sredstvo za stabiliziranje

Country Status (39)

Country Link
US (4) US7229982B2 (sl)
EP (2) EP1992343A1 (sl)
JP (2) JP2005538104A (sl)
KR (2) KR20050045993A (sl)
CN (2) CN101069684A (sl)
AR (2) AR040588A1 (sl)
AT (1) ATE393628T1 (sl)
AU (2) AU2003261217B2 (sl)
BR (1) BR0312933A (sl)
CA (1) CA2493076A1 (sl)
CR (1) CR9767A (sl)
DE (1) DE60320652T2 (sl)
DK (1) DK1531805T3 (sl)
EA (1) EA008888B1 (sl)
EC (2) ECSP055573A (sl)
ES (1) ES2303603T3 (sl)
GE (1) GEP20084443B (sl)
GT (2) GT200300149AA (sl)
HK (1) HK1080384A1 (sl)
HR (2) HRP20050081A2 (sl)
IL (2) IL166279A0 (sl)
IS (1) IS7637A (sl)
MA (1) MA27289A1 (sl)
ME (3) ME00207B (sl)
MX (1) MXPA05001004A (sl)
MY (1) MY148689A (sl)
NO (2) NO20051033L (sl)
NZ (1) NZ537611A (sl)
PA (1) PA8577901A1 (sl)
PE (1) PE20050128A1 (sl)
PL (1) PL375065A1 (sl)
PT (1) PT1531805E (sl)
RS (2) RS50419B (sl)
SI (1) SI1531805T1 (sl)
TN (1) TNSN05022A1 (sl)
TW (2) TW200906388A (sl)
UA (1) UA82489C2 (sl)
WO (1) WO2004010993A1 (sl)
ZA (1) ZA200500196B (sl)

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