SI1266896T1 - Linearne ali ciklicne secnine, postopek za njihovo pripravo in farmacevtski sestavki, ki jih vsebujejo - Google Patents

Linearne ali ciklicne secnine, postopek za njihovo pripravo in farmacevtski sestavki, ki jih vsebujejo

Info

Publication number
SI1266896T1
SI1266896T1 SI200030933T SI200030933T SI1266896T1 SI 1266896 T1 SI1266896 T1 SI 1266896T1 SI 200030933 T SI200030933 T SI 200030933T SI 200030933 T SI200030933 T SI 200030933T SI 1266896 T1 SI1266896 T1 SI 1266896T1
Authority
SI
Slovenia
Prior art keywords
het
bicyclic
direct bond
alkylene
formula
Prior art date
Application number
SI200030933T
Other languages
English (en)
Inventor
Jean-Louis Peglion
Christophe Poitevin
Jean-Paul Vilaine
Nicole Villeneuve
Marie-Pierre Bourguignon
Catherine Thollon
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of SI1266896T1 publication Critical patent/SI1266896T1/sl

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F21LIGHTING
    • F21SNON-PORTABLE LIGHTING DEVICES; SYSTEMS THEREOF; VEHICLE LIGHTING DEVICES SPECIALLY ADAPTED FOR VEHICLE EXTERIORS
    • F21S8/00Lighting devices intended for fixed installation
    • F21S8/03Lighting devices intended for fixed installation of surface-mounted type
    • F21S8/033Lighting devices intended for fixed installation of surface-mounted type the surface being a wall or like vertical structure, e.g. building facade
    • F21S8/036Lighting devices intended for fixed installation of surface-mounted type the surface being a wall or like vertical structure, e.g. building facade by means of a rigid support, e.g. bracket or arm
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F21LIGHTING
    • F21VFUNCTIONAL FEATURES OR DETAILS OF LIGHTING DEVICES OR SYSTEMS THEREOF; STRUCTURAL COMBINATIONS OF LIGHTING DEVICES WITH OTHER ARTICLES, NOT OTHERWISE PROVIDED FOR
    • F21V21/00Supporting, suspending, or attaching arrangements for lighting devices; Hand grips
    • F21V21/02Wall, ceiling, or floor bases; Fixing pendants or arms to the bases
    • F21V21/04Recessed bases
    • F21V21/041Mounting arrangements specially adapted for false ceiling panels or partition walls made of plates
    • F21V21/042Mounting arrangements specially adapted for false ceiling panels or partition walls made of plates using clamping means, e.g. for clamping with panel or wall
    • F21V21/043Mounting arrangements specially adapted for false ceiling panels or partition walls made of plates using clamping means, e.g. for clamping with panel or wall actuated by screwing
SI200030933T 1999-12-30 2000-12-26 Linearne ali ciklicne secnine, postopek za njihovo pripravo in farmacevtski sestavki, ki jih vsebujejo SI1266896T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9916701A FR2803298A1 (fr) 1999-12-30 1999-12-30 Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP02078578A EP1266896B1 (fr) 1999-12-30 2000-12-26 Urées linéaires ou cycliques, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
SI1266896T1 true SI1266896T1 (sl) 2007-04-30

Family

ID=9554011

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200030677T SI1113014T1 (sl) 1999-12-30 2000-12-26
SI200030933T SI1266896T1 (sl) 1999-12-30 2000-12-26 Linearne ali ciklicne secnine, postopek za njihovo pripravo in farmacevtski sestavki, ki jih vsebujejo

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI200030677T SI1113014T1 (sl) 1999-12-30 2000-12-26

Country Status (24)

Country Link
US (4) US6566364B2 (sl)
EP (2) EP1113014B1 (sl)
JP (2) JP3396671B2 (sl)
KR (2) KR100511134B1 (sl)
CN (1) CN1189466C (sl)
AT (1) ATE294170T1 (sl)
AU (1) AU776125B2 (sl)
BR (1) BR0007348A (sl)
CA (1) CA2330351C (sl)
CY (1) CY1106396T1 (sl)
DE (2) DE60019716T2 (sl)
DK (2) DK1266896T3 (sl)
EA (1) EA004040B1 (sl)
ES (2) ES2280482T3 (sl)
FR (1) FR2803298A1 (sl)
HK (1) HK1037183A1 (sl)
HU (1) HUP0005014A2 (sl)
MX (1) MXPA00012672A (sl)
NO (1) NO20006708L (sl)
NZ (1) NZ509119A (sl)
PL (1) PL344854A1 (sl)
PT (2) PT1266896E (sl)
SI (2) SI1113014T1 (sl)
ZA (1) ZA200100022B (sl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627645B2 (en) * 2000-04-28 2003-09-30 Acadia Pharmaceuticals, Inc. Muscarinic agonists
EP1535912A1 (en) * 2000-04-28 2005-06-01 Arcadia Pharmaceuticals Inc. Muscarinic agonists
AU2003248122A1 (en) * 2002-07-25 2004-02-16 Kotobuki Pharmaceutical Co., Ltd. Sodium channel inhibitor
CN106661009B (zh) * 2014-04-28 2019-11-26 江苏康缘药业股份有限公司 抗肠病毒71噻二唑烷衍生物
WO2015184222A1 (en) * 2014-05-30 2015-12-03 Southern Research Institute Inhibitors of hepatocyte growth factor [hgf] and macrophage stimulating protein [msp] maturation
CN109824600B (zh) * 2017-11-23 2020-10-02 中国科学院大连化学物理研究所 一种钯催化2-羟基嘧啶化合物的不对称氢化合成手性环状脲的方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1695735A1 (de) * 1966-06-14 1971-04-22 Searle & Co Verfahren zur Herstellung neuer 3-Phenyl-2-(1H)-chinazolinon-Derivate
CH598251A5 (sl) * 1972-08-24 1978-04-28 Ciba Geigy Ag
FR2300563A1 (fr) * 1975-02-13 1976-09-10 Sandoz Sa Nouveaux derives du thiazole, leur preparation et leur application comme medicaments
ZA76475B (en) * 1975-03-10 1977-08-31 Ciba Geigy Ag Indolyalkylpiperidines
DE2701794A1 (de) * 1976-01-21 1977-07-28 Ciba Geigy Ag Oxigenierte n-aryl-diazacyclen
DE2924064A1 (de) * 1979-06-15 1980-12-18 Boehringer Sohn Ingelheim Neue 1- eckige klammer auf n-phenylalkyl-piperidyl-(4) eckige klammer zu -imidazolidinone-(2) und verfahren zu ihrer herstellung
JPS62135464A (ja) * 1985-12-10 1987-06-18 Nippon Kayaku Co Ltd フエニルピペラジン誘導体
WO1992000282A1 (en) * 1990-06-29 1992-01-09 The Upjohn Company Substituted 1-(alkoxyphenyl)piperazines with cns and antihypertensive activity
EP0597112A4 (en) * 1992-03-27 1994-06-22 Kyoto Pharma Ind Novel imidazole derivative, pharmaceutical use thereof, and intermediate therefor.
CA2107196A1 (en) * 1992-09-29 1994-03-30 Mitsubishi Chemical Corporation Carboxamide derivatives
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser
US5362744A (en) * 1993-11-22 1994-11-08 Warner-Lambert Company Tetrazole-substituted urea acat inhibitors
IL114027A (en) * 1994-06-08 1999-11-30 Lundbeck & Co As H 4-Phenyl piperazine (piperidine or tetrahydropyridine) derivatives serotinin 5-HT1A and dopamin D2 receptor ligand pharmaceutical compositions containing them
FR2744451B1 (fr) * 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
FR2749304B1 (fr) * 1996-06-04 1998-06-26 Adir Nouveaux derives du 3-(piperid-4-yl)1,2-benzisoxazole et du 3-(piperazin-4-yl)1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2750991A1 (fr) * 1996-07-12 1998-01-16 Pf Medicament Nouveaux benzodioxannes et 1-(2h)-benzopyrannes, leur preparation et leur utilisation comme medicament
FR2755690B1 (fr) * 1996-11-08 1998-12-18 Adir Nouveaux derives aminomethyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2761069A1 (fr) * 1997-03-20 1998-09-25 Pf Medicament Spiroamines derivees de dihydrobenzofuranes, leur preparation et leur application comme medicaments
NO310618B1 (no) * 1997-04-10 2001-07-30 Ono Pharmaceutical Co Kondenserte piperidinforbindelser, fremstilling og anvendelse derav, samt preparater omfattende slike forbindelser

Also Published As

Publication number Publication date
DE60033060D1 (de) 2007-03-08
EP1113014A1 (fr) 2001-07-04
US6903103B2 (en) 2005-06-07
SI1113014T1 (sl) 2005-08-31
JP3942935B2 (ja) 2007-07-11
PT1266896E (pt) 2007-03-30
NO20006708L (no) 2001-07-02
EA200001248A1 (ru) 2001-08-27
ES2240035T3 (es) 2005-10-16
CA2330351C (fr) 2005-11-15
US20030225105A1 (en) 2003-12-04
ZA200100022B (en) 2001-07-18
US6908922B2 (en) 2005-06-21
MXPA00012672A (es) 2003-04-25
JP2001187782A (ja) 2001-07-10
CA2330351A1 (fr) 2001-06-30
DE60033060T2 (de) 2007-10-31
EA004040B1 (ru) 2003-12-25
HU0005014D0 (en) 2001-03-28
NZ509119A (en) 2001-09-28
DE60019716D1 (de) 2005-06-02
DE60019716T2 (de) 2006-01-19
AU7259400A (en) 2001-07-05
KR20010082612A (ko) 2001-08-30
ATE294170T1 (de) 2005-05-15
EP1266896B1 (fr) 2007-01-17
CN1301699A (zh) 2001-07-04
JP2002338566A (ja) 2002-11-27
US20010009911A1 (en) 2001-07-26
ES2280482T3 (es) 2007-09-16
KR100511134B1 (ko) 2005-08-31
DK1113014T3 (da) 2005-08-29
HK1037183A1 (en) 2002-02-01
HUP0005014A2 (en) 2002-06-29
US20030191132A1 (en) 2003-10-09
KR100477384B1 (ko) 2005-03-18
CN1189466C (zh) 2005-02-16
US20030229100A1 (en) 2003-12-11
EP1113014B1 (fr) 2005-04-27
US6780868B2 (en) 2004-08-24
CY1106396T1 (el) 2011-10-12
PT1113014E (pt) 2005-07-29
BR0007348A (pt) 2001-12-04
FR2803298A1 (fr) 2001-07-06
AU776125B2 (en) 2004-08-26
DK1266896T3 (da) 2007-05-21
KR20040030038A (ko) 2004-04-08
US6566364B2 (en) 2003-05-20
NO20006708D0 (no) 2000-12-29
EP1266896A1 (fr) 2002-12-18
PL344854A1 (en) 2001-07-02
JP3396671B2 (ja) 2003-04-14

Similar Documents

Publication Publication Date Title
DE69710319T2 (de) Para-substituierte phenylpropansäure derivate als integrin-antagonisten
WO2001056989A3 (en) Inhibitors of factor xa
ZA200203315B (en) Stable salts of novel derivatives of 3,3-diphenylpropylamines.
DK1029853T3 (da) Heteroaromatiske bicykliske derivativer, der er egnede som anticancermidler
CO5580826A2 (es) Compuestos de quinolona terapeuticos con propiedades antagonistas de 5ht
DK0889877T3 (da) Meta-substituerede phenylenderivater og deres anvendelse som alfav-beta3-integrin-antagonister eller -inhibitorer
CY1110382T1 (el) Πυραζινο υποκατεστημενες αρυλοβενζοδιαζεπινες
WO2002026712A3 (en) Quaternary amines and related inhibitors of factor xa
DK0928788T3 (da) Imidazolidin-4-on-derivater, der er nyttige som anticancer-midler
AR043684A1 (es) Inhibidores de ccr8, compuesto, composicion farmaceutica y usos
WO1998009953A3 (de) Azinyloxy- und phenoxy-diaryl-carbonsäure derivate, deren herstellung und deren verwendung als gemischte eta/etb endothelin-rezeptorantagonist
YU52000A (sh) Jedinjenja meta-azaciklične amino benzojeve kiseline i njihovi derivati, koji su antagonisti integrina
YU53100A (sh) Derivati 2-ariletil-(piperidin-4-ilmetil)amina kao antagonisti muskarinskih receptora
ES2038678T3 (es) Procedimiento para la preparacion de n-(2-alquil-3-mercapto-glutaril)-alfamino-acidos.
WO2001057021A3 (en) 2-[1H]-QUINOLONE AND 2-[1H]-QUINOXALONE INHIBITORS OF FACTOR Xa
DE60111464D1 (de) Azabicycloalkan-Derivate zur Verwendung als Inhibitoren der Serotonin-Wiederaufnahme und als 5HT2a Antagonisten
HK1037183A1 (en) New linear or cyclic ureas, a process for their preparation and pharmaceutical compositions containing them.
WO2001072708A3 (en) OXINDOLE INHIBITORS OF FACTOR Xa
WO2002036553A3 (en) Substituted alkanoic acids
WO2002026720A3 (en) PIPERAZINE BASED INHIBITORS OF FACTOR Xa
NZ514758A (en) Cyclobutenedione compounds to treat conditions in which endothelial dysfunction is known
TR200402720T4 (tr) Metalloproteaz inhibitörleri olarak 2-(4-piridinil)-benzofüran'lar
BG104718A (en) Pde iv inhibiting pyridine derivatives
WO2002026718A3 (en) Bicyclic pyrimidin-4-one based inhibitors of factor xa
ES2172436A1 (es) Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.