SI1226269T1 - Assay - Google Patents

Assay

Info

Publication number
SI1226269T1
SI1226269T1 SI200030178T SI200030178T SI1226269T1 SI 1226269 T1 SI1226269 T1 SI 1226269T1 SI 200030178 T SI200030178 T SI 200030178T SI 200030178 T SI200030178 T SI 200030178T SI 1226269 T1 SI1226269 T1 SI 1226269T1
Authority
SI
Slovenia
Prior art keywords
sample
tpa
endogenous
chromatography step
cho
Prior art date
Application number
SI200030178T
Other languages
English (en)
Slovenian (sl)
Inventor
Yuan Xu
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of SI1226269T1 publication Critical patent/SI1226269T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/972—Plasminogen activators
    • G01N2333/9726—Tissue plasminogen activator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Peptides Or Proteins (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
  • Glass Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
SI200030178T 1999-11-04 2000-11-01 Assay SI1226269T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16360799P 1999-11-04 1999-11-04
PCT/US2000/030252 WO2001032915A2 (fr) 1999-11-04 2000-11-01 Methode de chromatographie liquide a haute performance en phase inverse pour activateurs de plasminogene
EP00978343A EP1226269B1 (fr) 1999-11-04 2000-11-01 Essai

Publications (1)

Publication Number Publication Date
SI1226269T1 true SI1226269T1 (en) 2003-12-31

Family

ID=22590762

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030178T SI1226269T1 (en) 1999-11-04 2000-11-01 Assay

Country Status (24)

Country Link
US (2) US6593097B1 (fr)
EP (1) EP1226269B1 (fr)
JP (1) JP4659320B2 (fr)
KR (1) KR100649043B1 (fr)
CN (1) CN1167808C (fr)
AT (1) ATE243263T1 (fr)
AU (1) AU781023B2 (fr)
BR (1) BRPI0015283B8 (fr)
CA (1) CA2384756C (fr)
CZ (1) CZ302023B6 (fr)
DE (1) DE60003449T2 (fr)
DK (1) DK1226269T3 (fr)
ES (1) ES2200973T3 (fr)
HK (1) HK1046158B (fr)
HU (1) HU226202B1 (fr)
IL (1) IL149006A0 (fr)
MX (1) MXPA02004401A (fr)
NO (1) NO329876B1 (fr)
NZ (1) NZ518187A (fr)
PL (1) PL204011B1 (fr)
PT (1) PT1226269E (fr)
SI (1) SI1226269T1 (fr)
WO (1) WO2001032915A2 (fr)
ZA (1) ZA200202687B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2392753A1 (fr) 1999-12-10 2001-06-14 Invitrogen Corporation Utilisation de sites de recombinaison multiples avec une specificite unique dans le clonage de recombinaison
CA2430947A1 (fr) 2000-12-08 2002-06-13 Invitrogen Corporation Methodes et compositions destinees a la synthese de molecules d'acide nucleique a l'aide de sites de reconnaissance multiples
US6972327B1 (en) * 2001-05-08 2005-12-06 Immunex Corporation Regeneration of chromatography material
WO2006126942A1 (fr) * 2005-05-24 2006-11-30 Ge Healthcare Bio-Sciences Ab Regeneration d'une matrice de chromatographie
KR100701265B1 (ko) * 2006-01-16 2007-04-02 대한민국 재조합 사람 조직형 플라스미노겐 활성인자 발현벡터 및 플라스미노겐 활성인자를 소변으로 분비하는 형질전환돼지 생산방법
CL2007002615A1 (es) * 2006-09-08 2008-04-18 Wyeth Corp Metodos para aislar o purificar un producto que comprende poner el producto enlazado en contacto con al menos una solucion de lavado que comprende arginina y luego eluir el producto; y dicho producto.
EP2402752A3 (fr) * 2006-10-27 2012-06-06 Janssen Pharmaceutica, N.V. Procédé de profilage pharmacologique de composés
CN101539550B (zh) * 2009-04-28 2012-05-23 李绍平 用于多糖的定性与定量分析方法
US20200017771A1 (en) 2017-03-09 2020-01-16 Universitaet Des Saarlandes Means and methods for lignin pyrolysis
CN108333281A (zh) * 2018-02-08 2018-07-27 吉林大学 一种测定重组人粒细胞集落刺激因子二硫键组成的方法
CN108918749B (zh) * 2018-07-17 2020-05-05 北京赛升药业股份有限公司 一种蛇毒纤溶酶的反相hplc检测方法
CN114426962A (zh) * 2021-12-21 2022-05-03 佛山汉腾生物科技有限公司 t-PA纯化方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766075A (en) 1982-07-14 1988-08-23 Genentech, Inc. Human tissue plasminogen activator
FI831484L (fi) 1982-05-05 1983-11-06 Genentech Inc Plasminogen aktivator foer maenskovaevnad
US4777043A (en) * 1985-12-17 1988-10-11 Genentech, Inc. Stabilized human tissue plasminogen activator compositions
US5120535A (en) * 1986-11-26 1992-06-09 Oncogen Oncostatin M and novel compositions having anti-neoplastic activity
US5411864A (en) * 1987-11-05 1995-05-02 Genentech, Inc. Method of purifying recombinant proteins from corresponding host cell proteins
GB8919803D0 (en) * 1989-09-01 1989-10-18 Ciba Geigy Pharmaceutical compositions
DK0643772T3 (da) 1992-06-03 1998-02-02 Genentech Inc Glycosyleringsvarianter af vævsplasminogenaktivator med forbedrede terapeutiske egenskaber
US5753702A (en) * 1996-05-22 1998-05-19 University Of Vermont Arachidonic acid metabolite, 16-hete

Also Published As

Publication number Publication date
CN1387579A (zh) 2002-12-25
DE60003449T2 (de) 2004-05-06
HK1046158A1 (en) 2002-12-27
BRPI0015283B1 (pt) 2015-03-17
PL355389A1 (en) 2004-04-19
AU781023B2 (en) 2005-04-28
US6593097B1 (en) 2003-07-15
NZ518187A (en) 2002-12-20
WO2001032915A2 (fr) 2001-05-10
BRPI0015283B8 (pt) 2021-07-06
CA2384756A1 (fr) 2001-05-10
DK1226269T3 (da) 2003-10-13
ES2200973T3 (es) 2004-03-16
KR100649043B1 (ko) 2006-11-27
BRPI0015283A (pt) 2002-07-02
HU226202B1 (en) 2008-06-30
PT1226269E (pt) 2003-11-28
HUP0202973A2 (hu) 2002-12-28
NO329876B1 (no) 2011-01-17
WO2001032915A3 (fr) 2002-03-07
JP2003513638A (ja) 2003-04-15
MXPA02004401A (es) 2002-09-02
IL149006A0 (en) 2002-11-10
CN1167808C (zh) 2004-09-22
JP4659320B2 (ja) 2011-03-30
CZ20021196A3 (cs) 2002-08-14
PL204011B1 (pl) 2009-12-31
ZA200202687B (en) 2003-06-25
NO20022122D0 (no) 2002-05-03
AU1581601A (en) 2001-05-14
EP1226269A2 (fr) 2002-07-31
CZ302023B6 (cs) 2010-09-08
HUP0202973A3 (en) 2005-11-28
KR20020070431A (ko) 2002-09-09
US6828118B2 (en) 2004-12-07
ATE243263T1 (de) 2003-07-15
EP1226269B1 (fr) 2003-06-18
DE60003449D1 (de) 2003-07-24
US20030199016A1 (en) 2003-10-23
HK1046158B (zh) 2003-11-28
NO20022122L (no) 2002-07-03
CA2384756C (fr) 2010-09-28

Similar Documents

Publication Publication Date Title
HK1046158A1 (en) Assay
Church et al. Rapid sulfopropyl-disk chromatographic purification of bovine and human thrombin
McClure et al. Post-translational processing events in the secretion pathway of human protein C, a complex vitamin K-dependent antithrombotic factor.
US4461833A (en) Chromatographically purifying proteolytic procoagulant enzyme from animal tissue extract
Richo et al. Proteolytic activation of human procathepsin D
Roemisch et al. Quantitation of the factor VII-and single-chain plasminogen activator-activating protease in plasmas of healthy subjects
Wiman et al. Amino‐Acid Sequence of the Cyanogen‐Bromide Fragment from Human Plasminogen that Forms the Linkage between the Plasmin Chains
Kisiel et al. Isolation of a protein C activator from southern copperhead venom
US4229540A (en) Hydrolase purified from human plasma
Connellan et al. Partial purification of Factors XI and XIa: A comparison of their molecular size and structure
Engel et al. Molecular changes during prothrombin activation
Lau et al. Identification of plasmin as the major contaminant in immunoglobulin preparations
Cohen et al. Partial purification and characterization of the high molecular weight latent collagenase from human leukocytes
Tanaka et al. High-molecular-weight renin converting enzyme from dog kidney: detection and fractionation
Feigert et al. 248 Tissue plasminogen activator binds to immobilized immunoglobulin G: Enhancement by plasmin, and the identification of plasmin-derived fab s the TPA-binding fragment
CA2284122A1 (fr) Facteur sanguin active dependant de la vitamine k et procede de preparation dudit facteur