IL149006A0 - Reversed-phase hplc for plasminogen activators - Google Patents

Reversed-phase hplc for plasminogen activators

Info

Publication number
IL149006A0
IL149006A0 IL14900600A IL14900600A IL149006A0 IL 149006 A0 IL149006 A0 IL 149006A0 IL 14900600 A IL14900600 A IL 14900600A IL 14900600 A IL14900600 A IL 14900600A IL 149006 A0 IL149006 A0 IL 149006A0
Authority
IL
Israel
Prior art keywords
reversed
sample
tpa
endogenous
chromatography step
Prior art date
Application number
IL14900600A
Other languages
English (en)
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IL149006A0 publication Critical patent/IL149006A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/972—Plasminogen activators
    • G01N2333/9726—Tissue plasminogen activator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
IL14900600A 1999-11-04 2000-11-01 Reversed-phase hplc for plasminogen activators IL149006A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16360799P 1999-11-04 1999-11-04
PCT/US2000/030252 WO2001032915A2 (en) 1999-11-04 2000-11-01 Reversed-phase hplc assay for plasminogen activators

Publications (1)

Publication Number Publication Date
IL149006A0 true IL149006A0 (en) 2002-11-10

Family

ID=22590762

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14900600A IL149006A0 (en) 1999-11-04 2000-11-01 Reversed-phase hplc for plasminogen activators

Country Status (24)

Country Link
US (2) US6593097B1 (xx)
EP (1) EP1226269B1 (xx)
JP (1) JP4659320B2 (xx)
KR (1) KR100649043B1 (xx)
CN (1) CN1167808C (xx)
AT (1) ATE243263T1 (xx)
AU (1) AU781023B2 (xx)
BR (1) BRPI0015283B8 (xx)
CA (1) CA2384756C (xx)
CZ (1) CZ302023B6 (xx)
DE (1) DE60003449T2 (xx)
DK (1) DK1226269T3 (xx)
ES (1) ES2200973T3 (xx)
HK (1) HK1046158B (xx)
HU (1) HU226202B1 (xx)
IL (1) IL149006A0 (xx)
MX (1) MXPA02004401A (xx)
NO (1) NO329876B1 (xx)
NZ (1) NZ518187A (xx)
PL (1) PL204011B1 (xx)
PT (1) PT1226269E (xx)
SI (1) SI1226269T1 (xx)
WO (1) WO2001032915A2 (xx)
ZA (1) ZA200202687B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE391789T1 (de) 1999-12-10 2008-04-15 Invitrogen Corp Verwendung einer vielzahl von rekombinationsstellen mit einzigartiger spezifität beim rekombinatorischen klonen
AU2715302A (en) 2000-12-08 2002-06-18 Invitrogen Corp Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US6972327B1 (en) * 2001-05-08 2005-12-06 Immunex Corporation Regeneration of chromatography material
EP1885488B1 (en) * 2005-05-24 2015-07-08 GE Healthcare Bio-Sciences AB Regeneration of a chromatography matrix
KR100701265B1 (ko) * 2006-01-16 2007-04-02 대한민국 재조합 사람 조직형 플라스미노겐 활성인자 발현벡터 및 플라스미노겐 활성인자를 소변으로 분비하는 형질전환돼지 생산방법
CN101511387A (zh) * 2006-09-08 2009-08-19 惠氏公司 使用亲和色谱法纯化蛋白质的精氨酸洗涤液
JP2010507384A (ja) * 2006-10-27 2010-03-11 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ キナーゼ阻害剤のプロファイリング方法
CN101539550B (zh) * 2009-04-28 2012-05-23 李绍平 用于多糖的定性与定量分析方法
EP3592858A1 (en) 2017-03-09 2020-01-15 Universität des Saarlandes Means and methods for lignin pyrolysis
CN108333281A (zh) * 2018-02-08 2018-07-27 吉林大学 一种测定重组人粒细胞集落刺激因子二硫键组成的方法
CN108918749B (zh) * 2018-07-17 2020-05-05 北京赛升药业股份有限公司 一种蛇毒纤溶酶的反相hplc检测方法
CN114426962A (zh) * 2021-12-21 2022-05-03 佛山汉腾生物科技有限公司 t-PA纯化方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI831484L (fi) 1982-05-05 1983-11-06 Genentech Inc Plasminogen aktivator foer maenskovaevnad
US4766075A (en) 1982-07-14 1988-08-23 Genentech, Inc. Human tissue plasminogen activator
US4777043A (en) * 1985-12-17 1988-10-11 Genentech, Inc. Stabilized human tissue plasminogen activator compositions
US5120535A (en) * 1986-11-26 1992-06-09 Oncogen Oncostatin M and novel compositions having anti-neoplastic activity
US5411864A (en) * 1987-11-05 1995-05-02 Genentech, Inc. Method of purifying recombinant proteins from corresponding host cell proteins
GB8919803D0 (en) * 1989-09-01 1989-10-18 Ciba Geigy Pharmaceutical compositions
DE10199044I2 (de) 1992-06-03 2006-02-09 Genentech Inc Varianten des Gewebeplasminogenaktivators mit verbesserter Therapeutischer wirkung
US5753702A (en) * 1996-05-22 1998-05-19 University Of Vermont Arachidonic acid metabolite, 16-hete

Also Published As

Publication number Publication date
CZ20021196A3 (cs) 2002-08-14
PL204011B1 (pl) 2009-12-31
KR20020070431A (ko) 2002-09-09
CN1167808C (zh) 2004-09-22
NO329876B1 (no) 2011-01-17
PT1226269E (pt) 2003-11-28
JP4659320B2 (ja) 2011-03-30
NO20022122L (no) 2002-07-03
ZA200202687B (en) 2003-06-25
BRPI0015283B1 (pt) 2015-03-17
CZ302023B6 (cs) 2010-09-08
BRPI0015283B8 (pt) 2021-07-06
US20030199016A1 (en) 2003-10-23
AU781023B2 (en) 2005-04-28
PL355389A1 (en) 2004-04-19
NZ518187A (en) 2002-12-20
US6593097B1 (en) 2003-07-15
HK1046158B (zh) 2003-11-28
MXPA02004401A (es) 2002-09-02
EP1226269B1 (en) 2003-06-18
WO2001032915A3 (en) 2002-03-07
BRPI0015283A (pt) 2002-07-02
AU1581601A (en) 2001-05-14
HUP0202973A2 (hu) 2002-12-28
ATE243263T1 (de) 2003-07-15
HK1046158A1 (en) 2002-12-27
DK1226269T3 (da) 2003-10-13
KR100649043B1 (ko) 2006-11-27
WO2001032915A2 (en) 2001-05-10
NO20022122D0 (no) 2002-05-03
HUP0202973A3 (en) 2005-11-28
ES2200973T3 (es) 2004-03-16
CA2384756C (en) 2010-09-28
CN1387579A (zh) 2002-12-25
HU226202B1 (en) 2008-06-30
SI1226269T1 (en) 2003-12-31
DE60003449T2 (de) 2004-05-06
EP1226269A2 (en) 2002-07-31
CA2384756A1 (en) 2001-05-10
JP2003513638A (ja) 2003-04-15
DE60003449D1 (de) 2003-07-24
US6828118B2 (en) 2004-12-07

Similar Documents

Publication Publication Date Title
IL149006A0 (en) Reversed-phase hplc for plasminogen activators
Walker Regulation of activated protein C by a new protein. A possible function for bovine protein S.
McClure et al. Post-translational processing events in the secretion pathway of human protein C, a complex vitamin K-dependent antithrombotic factor.
Church et al. Rapid sulfopropyl-disk chromatographic purification of bovine and human thrombin
Samuels et al. A cuticle-degrading proteinase from the moulting fluid of the tobacco hornworm, Manduca sexta
Roemisch et al. Quantitation of the factor VII-and single-chain plasminogen activator-activating protease in plasmas of healthy subjects
Richo et al. Proteolytic activation of human procathepsin D
Wiman et al. Amino‐Acid Sequence of the Cyanogen‐Bromide Fragment from Human Plasminogen that Forms the Linkage between the Plasmin Chains
US4229540A (en) Hydrolase purified from human plasma
Connellan et al. Partial purification of Factors XI and XIa: A comparison of their molecular size and structure
Engel et al. Molecular changes during prothrombin activation
Cohen et al. Partial purification and characterization of the high molecular weight latent collagenase from human leukocytes
Lau et al. Identification of plasmin as the major contaminant in immunoglobulin preparations
Tanaka et al. High-molecular-weight renin converting enzyme from dog kidney: detection and fractionation
Feigert et al. 248 Tissue plasminogen activator binds to immobilized immunoglobulin G: Enhancement by plasmin, and the identification of plasmin-derived fab s the TPA-binding fragment
JPH0779692B2 (ja) 一本鎖ｔ−ＰＡと二本鎖ｔ−ＰＡを分離する方法
CA2284122A1 (en) Activated vitamin k-dependent blood factor and method for the production thereof
MXPA99008147A (en) Activated vitamin k-dependent blood factor and method for the production thereof

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed