ATE243263T1 - Testverfahren - Google Patents

Testverfahren

Info

Publication number
ATE243263T1
ATE243263T1 AT00978343T AT00978343T ATE243263T1 AT E243263 T1 ATE243263 T1 AT E243263T1 AT 00978343 T AT00978343 T AT 00978343T AT 00978343 T AT00978343 T AT 00978343T AT E243263 T1 ATE243263 T1 AT E243263T1
Authority
AT
Austria
Prior art keywords
sample
tpa
endogenous
chromatography step
cho
Prior art date
Application number
AT00978343T
Other languages
English (en)
Inventor
Yuan Xu
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE243263T1 publication Critical patent/ATE243263T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/972—Plasminogen activators
    • G01N2333/9726—Tissue plasminogen activator

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Peptides Or Proteins (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
  • Glass Compositions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT00978343T 1999-11-04 2000-11-01 Testverfahren ATE243263T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16360799P 1999-11-04 1999-11-04
PCT/US2000/030252 WO2001032915A2 (en) 1999-11-04 2000-11-01 Reversed-phase hplc assay for plasminogen activators

Publications (1)

Publication Number Publication Date
ATE243263T1 true ATE243263T1 (de) 2003-07-15

Family

ID=22590762

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00978343T ATE243263T1 (de) 1999-11-04 2000-11-01 Testverfahren

Country Status (24)

Country Link
US (2) US6593097B1 (de)
EP (1) EP1226269B1 (de)
JP (1) JP4659320B2 (de)
KR (1) KR100649043B1 (de)
CN (1) CN1167808C (de)
AT (1) ATE243263T1 (de)
AU (1) AU781023B2 (de)
BR (1) BRPI0015283B8 (de)
CA (1) CA2384756C (de)
CZ (1) CZ302023B6 (de)
DE (1) DE60003449T2 (de)
DK (1) DK1226269T3 (de)
ES (1) ES2200973T3 (de)
HK (1) HK1046158B (de)
HU (1) HU226202B1 (de)
IL (1) IL149006A0 (de)
MX (1) MXPA02004401A (de)
NO (1) NO329876B1 (de)
NZ (1) NZ518187A (de)
PL (1) PL204011B1 (de)
PT (1) PT1226269E (de)
SI (1) SI1226269T1 (de)
WO (1) WO2001032915A2 (de)
ZA (1) ZA200202687B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1757724B (zh) 1999-12-10 2014-06-11 茵维特罗根公司 具有独特特异性的多个重组位点在重组克隆中的用途
CA2430947A1 (en) 2000-12-08 2002-06-13 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
US6972327B1 (en) * 2001-05-08 2005-12-06 Immunex Corporation Regeneration of chromatography material
EP1885488B1 (de) * 2005-05-24 2015-07-08 GE Healthcare Bio-Sciences AB Regeneration einer chromatographiematrix
KR100701265B1 (ko) * 2006-01-16 2007-04-02 대한민국 재조합 사람 조직형 플라스미노겐 활성인자 발현벡터 및 플라스미노겐 활성인자를 소변으로 분비하는 형질전환돼지 생산방법
EP2059258B1 (de) * 2006-09-08 2019-11-13 Wyeth LLC Argininwaschung bei der proteinreinigung mittels affinitätschromatografie
JP2010507384A (ja) * 2006-10-27 2010-03-11 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ キナーゼ阻害剤のプロファイリング方法
CN101539550B (zh) * 2009-04-28 2012-05-23 李绍平 用于多糖的定性与定量分析方法
WO2018162612A1 (en) 2017-03-09 2018-09-13 Universitaet Des Saarlandes Means and methods for lignin pyrolysis
CN108333281A (zh) * 2018-02-08 2018-07-27 吉林大学 一种测定重组人粒细胞集落刺激因子二硫键组成的方法
CN108918749B (zh) * 2018-07-17 2020-05-05 北京赛升药业股份有限公司 一种蛇毒纤溶酶的反相hplc检测方法
CN114426962B (zh) * 2021-12-21 2024-06-18 佛山汉腾生物科技有限公司 t-PA纯化方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766075A (en) 1982-07-14 1988-08-23 Genentech, Inc. Human tissue plasminogen activator
FI831484L (fi) 1982-05-05 1983-11-06 Genentech Inc Plasminogen aktivator foer maenskovaevnad
US4777043A (en) * 1985-12-17 1988-10-11 Genentech, Inc. Stabilized human tissue plasminogen activator compositions
US5120535A (en) * 1986-11-26 1992-06-09 Oncogen Oncostatin M and novel compositions having anti-neoplastic activity
US5411864A (en) * 1987-11-05 1995-05-02 Genentech, Inc. Method of purifying recombinant proteins from corresponding host cell proteins
GB8919803D0 (en) * 1989-09-01 1989-10-18 Ciba Geigy Pharmaceutical compositions
AU664469B2 (en) 1992-06-03 1995-11-16 Genentech Inc. Tissue plasminogen activator glycosylation variants with improved therapeutic properties
US5753702A (en) * 1996-05-22 1998-05-19 University Of Vermont Arachidonic acid metabolite, 16-hete

Also Published As

Publication number Publication date
CZ20021196A3 (cs) 2002-08-14
HK1046158A1 (en) 2002-12-27
HU226202B1 (en) 2008-06-30
PL204011B1 (pl) 2009-12-31
ZA200202687B (en) 2003-06-25
US20030199016A1 (en) 2003-10-23
IL149006A0 (en) 2002-11-10
NO20022122L (no) 2002-07-03
BRPI0015283B8 (pt) 2021-07-06
EP1226269A2 (de) 2002-07-31
NO329876B1 (no) 2011-01-17
BRPI0015283A (pt) 2002-07-02
ES2200973T3 (es) 2004-03-16
CN1167808C (zh) 2004-09-22
BRPI0015283B1 (pt) 2015-03-17
AU1581601A (en) 2001-05-14
KR20020070431A (ko) 2002-09-09
MXPA02004401A (es) 2002-09-02
CZ302023B6 (cs) 2010-09-08
CA2384756C (en) 2010-09-28
NZ518187A (en) 2002-12-20
CA2384756A1 (en) 2001-05-10
JP4659320B2 (ja) 2011-03-30
CN1387579A (zh) 2002-12-25
US6828118B2 (en) 2004-12-07
AU781023B2 (en) 2005-04-28
DE60003449T2 (de) 2004-05-06
DK1226269T3 (da) 2003-10-13
HUP0202973A2 (hu) 2002-12-28
PT1226269E (pt) 2003-11-28
WO2001032915A2 (en) 2001-05-10
HK1046158B (zh) 2003-11-28
HUP0202973A3 (en) 2005-11-28
KR100649043B1 (ko) 2006-11-27
US6593097B1 (en) 2003-07-15
WO2001032915A3 (en) 2002-03-07
SI1226269T1 (en) 2003-12-31
EP1226269B1 (de) 2003-06-18
JP2003513638A (ja) 2003-04-15
NO20022122D0 (no) 2002-05-03
DE60003449D1 (de) 2003-07-24
PL355389A1 (en) 2004-04-19

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