SI1175429T1 - Halo derivati 9-deokso-9a-aza-9a-homoerotromicina A - Google Patents

Halo derivati 9-deokso-9a-aza-9a-homoerotromicina A

Info

Publication number
SI1175429T1
SI1175429T1 SI200030188T SI200030188T SI1175429T1 SI 1175429 T1 SI1175429 T1 SI 1175429T1 SI 200030188 T SI200030188 T SI 200030188T SI 200030188 T SI200030188 T SI 200030188T SI 1175429 T1 SI1175429 T1 SI 1175429T1
Authority
SI
Slovenia
Prior art keywords
meaning
halo
deoxo
aza
homerythromycin
Prior art date
Application number
SI200030188T
Other languages
English (en)
Inventor
Zorica Marusic-Istuk
Nedjeljko Kujundzic
Gabrijela Kobrehel
Stjepan Mutak
Natasa Marsic
Original Assignee
PLIVA farmaceutska industrija, dioni�ko dru�tvo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PLIVA farmaceutska industrija, dioni�ko dru�tvo filed Critical PLIVA farmaceutska industrija, dioni�ko dru�tvo
Publication of SI1175429T1 publication Critical patent/SI1175429T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SI200030188T 1999-05-03 2000-05-02 Halo derivati 9-deokso-9a-aza-9a-homoerotromicina A SI1175429T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HR990130A HRP990130B1 (en) 1999-05-03 1999-05-03 HALOGEN DERIVATIVES 9a-N-(N'-ARYLCARBAMOYL)- AND 9a-N-(N'-ARYLTHIOCARBAMOYL)-9-DEOXO-9a-AZA-9a OF HOMOERYTHROMYCIN A
PCT/HR2000/000013 WO2000066603A1 (en) 1999-05-03 2000-05-02 Halo derivatives of 9-deoxo-9a-aza-9a-homerythromycin a
EP00920940A EP1175429B1 (en) 1999-05-03 2000-05-02 Halo derivatives of 9-deoxo-9a-aza-9a-homerythromycin a

Publications (1)

Publication Number Publication Date
SI1175429T1 true SI1175429T1 (sl) 2003-12-31

Family

ID=10946916

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030188T SI1175429T1 (sl) 1999-05-03 2000-05-02 Halo derivati 9-deokso-9a-aza-9a-homoerotromicina A

Country Status (33)

Country Link
US (1) US6872707B1 (sl)
EP (1) EP1175429B1 (sl)
JP (1) JP2002543213A (sl)
KR (1) KR100714740B1 (sl)
CN (1) CN1140535C (sl)
AT (1) ATE244258T1 (sl)
AU (1) AU767681B2 (sl)
BG (1) BG106173A (sl)
BR (1) BR0010231A (sl)
CA (1) CA2372977A1 (sl)
CZ (1) CZ20013913A3 (sl)
DE (1) DE60003671T2 (sl)
DK (1) DK1175429T3 (sl)
EA (1) EA005214B1 (sl)
EE (1) EE05007B1 (sl)
ES (1) ES2202107T3 (sl)
GE (1) GEP20032928B (sl)
HK (1) HK1045522B (sl)
HR (1) HRP990130B1 (sl)
HU (1) HUP0201146A3 (sl)
IL (2) IL145986A0 (sl)
IS (1) IS6115A (sl)
MX (1) MXPA01011038A (sl)
NO (1) NO320138B1 (sl)
NZ (1) NZ515278A (sl)
PL (1) PL351402A1 (sl)
PT (1) PT1175429E (sl)
SI (1) SI1175429T1 (sl)
SK (1) SK284513B6 (sl)
TR (1) TR200103143T2 (sl)
UA (1) UA71962C2 (sl)
WO (1) WO2000066603A1 (sl)
ZA (1) ZA200108484B (sl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20010146B1 (en) * 2001-02-28 2005-10-31 Pliva D.D. 9a-N-(N'-(PHENYLSULFONYL)CARBAMOYL) DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMYCIN A AND OF 5-O-DESOSAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHRONOLIDE A
HRP20020885B1 (en) 2002-11-11 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A
HRP20020886A2 (en) * 2002-11-11 2005-06-30 PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. SUBSTITUTED 9a-N-[N'-(BENZENSULFONYL)CARBAMOYL-γ-AMINOPROPYL) AND 9a-N(N' -(?-CYANOETHIL)-N' -(b
HRP20020991A2 (en) * 2002-12-12 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. N"-Substituted 9a-N-(N'-carbamoyl-Gamma-aminopropyl), 9a-N-(N'? -thiocarbamoyl-Gamma-aminopropyl), 9a-N-(N'-((Beta-cyanoethyl)-N'-carbamoyl-Gamma? -aminopropyl) and 9a-N-(N'-(Beta-cyanoethyl)-N'-thiocarbamoyl-Gamma? -aminopropyl) derivatives of 9-de
HRP20030381B1 (en) * 2003-05-14 2007-05-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 3-DECLADINOZYL 9a-N-CARBAMOYL AND 9a-N-THIOCARBAMOYL DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICYNE A
US20080227730A1 (en) * 2005-01-14 2008-09-18 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. 9A-Carbamoyl and Thiocarbamoyl Azalides With Antimalarial Activity
EP2203435B1 (en) * 2007-09-17 2018-07-18 Enanta Pharmaceuticals, Inc. 6, 11-bridged biaryl macrolides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU43116B (en) * 1979-04-02 1989-04-30 Pliva Pharm & Chem Works Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox
US5350839A (en) * 1990-10-15 1994-09-27 Taisho Pharmaceutical Co., Ltd. 2'-position modified compound of erythromycin or its derivative
HRP931480B1 (en) * 1993-12-08 1997-08-31 Sour Pliva 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A

Also Published As

Publication number Publication date
NO20015346L (no) 2001-11-01
EA005214B1 (ru) 2004-12-30
MXPA01011038A (es) 2002-07-22
NO320138B1 (no) 2005-10-31
KR100714740B1 (ko) 2007-05-07
SK284513B6 (sk) 2005-05-05
CN1140535C (zh) 2004-03-03
EP1175429B1 (en) 2003-07-02
DK1175429T3 (da) 2003-10-20
BG106173A (bg) 2002-07-31
HRP990130A2 (en) 2001-10-31
EA200101170A1 (ru) 2002-04-25
HRP990130B1 (en) 2004-06-30
BR0010231A (pt) 2002-02-19
UA71962C2 (en) 2005-01-17
CA2372977A1 (en) 2000-11-09
EP1175429A1 (en) 2002-01-30
AU4135000A (en) 2000-11-17
ZA200108484B (en) 2003-03-26
KR20020007397A (ko) 2002-01-26
HK1045522B (zh) 2004-08-20
HUP0201146A3 (en) 2003-03-28
PL351402A1 (en) 2003-04-07
IS6115A (is) 2001-10-19
EE200100582A (et) 2003-02-17
AU767681B2 (en) 2003-11-20
SK15702001A3 (sk) 2002-04-04
CN1351606A (zh) 2002-05-29
DE60003671T2 (de) 2004-06-17
ES2202107T3 (es) 2004-04-01
DE60003671D1 (de) 2003-08-07
EE05007B1 (et) 2008-04-15
IL145986A (en) 2006-10-31
GEP20032928B (en) 2003-03-25
IL145986A0 (en) 2002-07-25
HUP0201146A2 (hu) 2002-07-29
ATE244258T1 (de) 2003-07-15
TR200103143T2 (tr) 2002-04-22
US6872707B1 (en) 2005-03-29
WO2000066603A1 (en) 2000-11-09
HK1045522A1 (en) 2002-11-29
NZ515278A (en) 2003-06-30
JP2002543213A (ja) 2002-12-17
NO20015346D0 (no) 2001-11-01
CZ20013913A3 (cs) 2002-04-17
PT1175429E (pt) 2003-11-28

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