US5478577A
(en)
*
|
1993-11-23 |
1995-12-26 |
Euroceltique, S.A. |
Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
|
US5958459A
(en)
*
|
1991-12-24 |
1999-09-28 |
Purdue Pharma L.P. |
Opioid formulations having extended controlled released
|
US5968551A
(en)
|
1991-12-24 |
1999-10-19 |
Purdue Pharma L.P. |
Orally administrable opioid formulations having extended duration of effect
|
US5965161A
(en)
*
|
1994-11-04 |
1999-10-12 |
Euro-Celtique, S.A. |
Extruded multi-particulates
|
US5840731A
(en)
*
|
1995-08-02 |
1998-11-24 |
Virginia Commonwealth University |
Pain-alleviating drug composition and method for alleviating pain
|
US6017963A
(en)
|
1995-11-14 |
2000-01-25 |
Euro-Celtique, S.A. |
Formulation for intranasal administration
|
DE19601744C2
(de)
|
1996-01-19 |
1998-04-16 |
Gruenenthal Gmbh |
Verfahren zur Herstellung der Enantiomeren von O-Demethyltramadol
|
ZA975444B
(en)
*
|
1996-06-20 |
1998-12-21 |
Mcneil Ppc Inc |
Acetaminophen and meclizine hydrochloride analgesics
|
WO1998058637A1
(fr)
*
|
1996-06-20 |
1998-12-30 |
Mcneil-Ppc |
Analgesique a base d'acetaminophene et de diphenhydramine
|
DE19641576C1
(de)
*
|
1996-10-09 |
1998-05-07 |
Gruenenthal Gmbh |
Kombinationspräparat enthaltend Tramadol und einen Calcium-Kanal Antagonisten
|
US5919826A
(en)
*
|
1996-10-24 |
1999-07-06 |
Algos Pharmaceutical Corporation |
Method of alleviating pain
|
JP4085433B2
(ja)
*
|
1997-04-11 |
2008-05-14 |
日本新薬株式会社 |
頻尿・尿失禁治療剤
|
DE69809055T2
(de)
|
1997-07-15 |
2003-06-05 |
Russinsky Ltd., Cork |
Verfahren zur herstellung von reinem cis-tramadol
|
AU773642C
(en)
|
1997-12-22 |
2006-04-06 |
Mundipharma Pty Limited |
Opioid agonist/antagonist combinations
|
US6375957B1
(en)
|
1997-12-22 |
2002-04-23 |
Euro-Celtique, S.A. |
Opioid agonist/opioid antagonist/acetaminophen combinations
|
US6320214B1
(en)
*
|
1997-12-24 |
2001-11-20 |
Matsushita Electric Industrial Co., Ltd. |
Semiconductor device having a ferroelectric TFT and a dummy element
|
US6156342A
(en)
*
|
1998-05-26 |
2000-12-05 |
Andex Pharmaceuticals, Inc. |
Controlled release oral dosage form
|
MXPA02001820A
(es)
*
|
1999-08-20 |
2003-07-14 |
Johnson & Johnson |
Composicion que comprende un material de tramadol y un farmaco anticonvulsivo.
|
PE20010623A1
(es)
|
1999-10-05 |
2001-07-07 |
Gruenenthal Chemie |
Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria
|
US10179130B2
(en)
|
1999-10-29 |
2019-01-15 |
Purdue Pharma L.P. |
Controlled release hydrocodone formulations
|
BRPI0015284B8
(pt)
|
1999-10-29 |
2021-05-25 |
Euro Celtique S/A |
formulações de hidrocodona de liberação controlada
|
EP1313460A2
(fr)
*
|
1999-11-09 |
2003-05-28 |
Darwin Discovery Limited |
Utilisation therapeutique et formulation de (-)-tramadol
|
JP2003522144A
(ja)
|
2000-02-08 |
2003-07-22 |
ユーロ−セルティーク,エス.エイ. |
オピオイドアゴニストおよびアンタゴニストを含む制御放出組成物
|
DE60107393T2
(de)
*
|
2000-03-01 |
2005-12-01 |
Euro-Celtique S.A. |
Verwendung von tramadol zur herstellung eines arzneimittels zur behandlung von funktionelle gastrointestinale krankenheiten
|
KR101045144B1
(ko)
|
2000-10-30 |
2011-06-30 |
유로-셀티크 소시에떼 아노뉨 |
서방성 하이드로코돈 제형
|
DE10059020A1
(de)
*
|
2000-11-28 |
2002-05-29 |
Gruenenthal Gmbh |
Parenteral applizierbare Darreichungsformen
|
DE60211689T2
(de)
|
2001-03-16 |
2007-01-11 |
DMI Biosciences, Inc., Englewood |
Verwendung von Tramadol zur Verzögerung der Ejakulation
|
US20110104214A1
(en)
|
2004-04-15 |
2011-05-05 |
Purdue Pharma L.P. |
Once-a-day oxycodone formulations
|
EP1387673B1
(fr)
|
2001-05-11 |
2010-12-29 |
Endo Pharmaceuticals Inc. |
Forme posologique d'opioides a liberation prolongee empechant la consommation abusive
|
ES2319620T3
(es)
|
2001-07-18 |
2009-05-11 |
Euro-Celtique S.A. |
Conbinaciones farmaceuticas de oxicodona y naloxona.
|
SI1414451T1
(sl)
|
2001-08-06 |
2009-10-31 |
Euro Celtique Sa |
Formulacije opioidnega agonista s sproščanja sposobnim in sekvestriranim antagonistom
|
US20030044458A1
(en)
|
2001-08-06 |
2003-03-06 |
Curtis Wright |
Oral dosage form comprising a therapeutic agent and an adverse-effect agent
|
US20030157168A1
(en)
|
2001-08-06 |
2003-08-21 |
Christopher Breder |
Sequestered antagonist formulations
|
ES2733044T1
(es)
|
2002-04-05 |
2019-11-27 |
Mundipharma Pharmaceuticals S L |
Composición farmacéutica que contiene oxicodona y naloxona
|
EP1364649A1
(fr)
*
|
2002-05-23 |
2003-11-26 |
Cilag AG |
Produits d'addition de tramadol et topiramate et son utilization
|
EP2422775A3
(fr)
|
2002-09-20 |
2012-04-18 |
Alpharma, Inc. |
Séquestration de sous-unité et compositions et procédés associés
|
US20090162431A1
(en)
*
|
2002-09-21 |
2009-06-25 |
Shuyi Zhang |
Sustained release formulations containing acetaminophen and tramadol
|
EP1555022B1
(fr)
*
|
2002-09-21 |
2008-02-20 |
Shuyi Zhang |
Formulation d'acetaminophene et de tramadol a liberation prolongee
|
TWI319713B
(en)
|
2002-10-25 |
2010-01-21 |
|
Sustained-release tramadol formulations with 24-hour efficacy
|
US8487002B2
(en)
|
2002-10-25 |
2013-07-16 |
Paladin Labs Inc. |
Controlled-release compositions
|
US6864271B2
(en)
*
|
2002-11-12 |
2005-03-08 |
The Foundation For The Lsu Health Sciences Center |
Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives
|
KR20050075408A
(ko)
*
|
2002-12-13 |
2005-07-20 |
시락 아게 |
트라마돌 및 토피라메이트를 포함하는 방출 조절형 제제
|
US20040202717A1
(en)
|
2003-04-08 |
2004-10-14 |
Mehta Atul M. |
Abuse-resistant oral dosage forms and method of use thereof
|
TWI347201B
(en)
|
2003-04-21 |
2011-08-21 |
Euro Celtique Sa |
Pharmaceutical products,uses thereof and methods for preparing the same
|
US20050065172A1
(en)
*
|
2003-09-23 |
2005-03-24 |
Shah Indukumar G. |
Solid dosage form comprising caffeine
|
US20050067163A1
(en)
*
|
2003-09-25 |
2005-03-31 |
George Flint R. |
Monobore release for tubing conveyed perforating
|
US20060172006A1
(en)
*
|
2003-10-10 |
2006-08-03 |
Vincent Lenaerts |
Sustained-release tramadol formulations with 24-hour clinical efficacy
|
EP1604666A1
(fr)
|
2004-06-08 |
2005-12-14 |
Euro-Celtique S.A. |
Opioides pour le traitement de la bronchopneumopathie chronique obstructive
|
WO2006016126A1
(fr)
*
|
2004-08-12 |
2006-02-16 |
Reckitt Benckiser Healthcare (Uk) Limited |
Granules compose de paracetamol a ains et d’un polyol fabrique par extrusion de matiere fondue
|
CN100348180C
(zh)
*
|
2004-12-24 |
2007-11-14 |
河南大学 |
盐酸曲马多口腔崩解片剂及其制备方法
|
EP1702558A1
(fr)
|
2005-02-28 |
2006-09-20 |
Euro-Celtique S.A. |
Procédé et dispositif pour évaluer la fonction de l'activité intestinale
|
EP1917000A2
(fr)
|
2005-07-07 |
2008-05-07 |
Farnam Companies, Inc. |
Compositions pharmaceutiques a liberation prolongee pour medicaments tres solubles dans l'eau
|
ES2389666T3
(es)
|
2005-09-09 |
2012-10-30 |
Angelini Labopharm, Llc |
Composición de trazodona para una administración de una vez al día
|
CA2655835C
(fr)
|
2006-06-19 |
2015-07-21 |
Alpharma, Inc. |
Compositions pharmaceutiques d'agonistes opioides resistants a l'abus
|
US7645767B2
(en)
*
|
2006-08-31 |
2010-01-12 |
Trinity Laboratories, Inc. |
Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
|
EP2124556B1
(fr)
|
2006-10-09 |
2014-09-03 |
Charleston Laboratories, Inc. |
Compositions pharmaceutiques
|
DE102006056458A1
(de)
*
|
2006-11-28 |
2008-05-29 |
Grünenthal GmbH |
Arzneimittelzubereitung von Tramadol und Acetaminophen
|
PL2120570T3
(pl)
*
|
2007-02-12 |
2012-10-31 |
Vyrix Pharmaceuticals Inc |
Leczenie współwystępującego przedwczesnego wytrysku i zaburzenia wzwodu prącia
|
CA2677691C
(fr)
*
|
2007-02-12 |
2012-07-31 |
David Bar-Or |
Reduction des effets secondaires du tramadol
|
US20080031950A1
(en)
*
|
2007-04-27 |
2008-02-07 |
Nectid Inc. |
Novel anelgesic combination
|
US20080026054A1
(en)
*
|
2007-04-27 |
2008-01-31 |
Nectid Inc. |
Novel anelgesic combination
|
WO2009018169A1
(fr)
*
|
2007-07-27 |
2009-02-05 |
Auspex Pharmaceuticals, Inc. |
Cyclohexanols substitués
|
MX336494B
(es)
*
|
2007-10-16 |
2016-01-21 |
Paladin Labs Inc |
Composicion de bicapas para la liberacion controlada de acetaminofeno y tramadol.
|
JP5909750B2
(ja)
|
2007-11-13 |
2016-04-27 |
マリンクロット アイピー |
低用量静脈内アセトアミノフェン
|
US8623418B2
(en)
|
2007-12-17 |
2014-01-07 |
Alpharma Pharmaceuticals Llc |
Pharmaceutical composition
|
KR20100121463A
(ko)
|
2007-12-17 |
2010-11-17 |
라보팜 인코포레이트 |
오용 예방적 방출 제어형 제제
|
EP2240022B1
(fr)
*
|
2008-01-09 |
2016-12-28 |
Charleston Laboratories, Inc. |
Comprimés à deux couches contenant oxycodone et promethazine
|
CA2720108C
(fr)
|
2008-03-11 |
2016-06-07 |
Depomed, Inc. |
Formes medicamenteuses a liberation etendue de retention gastrique comprenant des combinaisons d'un analgesique non opioide et d'un analgesique opioide
|
US8372432B2
(en)
|
2008-03-11 |
2013-02-12 |
Depomed, Inc. |
Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic
|
US20100003322A1
(en)
*
|
2008-07-03 |
2010-01-07 |
Lai Felix S |
Enteric coated hydrophobic matrix formulation
|
KR20110059634A
(ko)
*
|
2008-09-05 |
2011-06-02 |
그뤼넨탈 게엠베하 |
6-디메틸아미노메틸-1-(3-메톡시-페닐)-사이클로헥산-1,3디올 및 파라세타몰을 포함하는 약제학적 병용물
|
EP2177215A1
(fr)
|
2008-10-17 |
2010-04-21 |
Laboratorios Del. Dr. Esteve, S.A. |
Co-cristaux de tramadol et NSAID
|
CN107028908A
(zh)
*
|
2008-10-27 |
2017-08-11 |
阿尔扎公司 |
对乙酰氨基酚/曲马多口服延释剂型
|
ES2509497T3
(es)
|
2008-12-16 |
2014-10-17 |
Paladin Labs Inc. |
Formulación de liberación controlada para evitar un uso indebido
|
UY32487A
(es)
|
2009-03-10 |
2010-06-30 |
Euro Celtique Sa |
Composiciones farmacéuticas de liberación inmediata comprendiendo oxicodona y naloxona
|
EP3311667A1
(fr)
|
2009-07-08 |
2018-04-25 |
Charleston Laboratories, Inc. |
Compositions pharmaceutiques
|
ES2353541B1
(es)
|
2009-07-30 |
2011-09-20 |
Farmalider, S.A. |
Combinacion de ingredientes activos cosmeticos y composicion cosmetica obtenida a partir de la misma, y su utilizacion.
|
EP2281558A1
(fr)
*
|
2009-08-06 |
2011-02-09 |
Laboratorios Del. Dr. Esteve, S.A. |
Composés pharmaceutique de O-desméthyl-tramadol et inhibiteurs COX
|
US20110104272A1
(en)
*
|
2009-11-05 |
2011-05-05 |
Depomed, Inc. |
Gastric retentive extended-release dosage forms comprising combinations of acetaminophen and phenylephrine
|
US8597681B2
(en)
|
2009-12-22 |
2013-12-03 |
Mallinckrodt Llc |
Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
|
US9198861B2
(en)
|
2009-12-22 |
2015-12-01 |
Mallinckrodt Llc |
Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
|
DE202010001237U1
(de)
|
2010-01-21 |
2010-04-01 |
Grünenthal GmbH |
Kombination aus Tramadol und Acetaminophen als Brausetablette
|
GR1007315B
(el)
*
|
2010-04-19 |
2011-06-14 |
Uni-Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Abee, |
Υγρομορφη παρεντερικης χορηγησης συνθεση που περιλαμβανει τραμαδολη hci και παρακεταμολη
|
EP2377514A3
(fr)
*
|
2010-04-19 |
2012-04-11 |
Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. |
Formulation parentérale liquide comportant un matériau de tramadol et paracétamol
|
US10010514B2
(en)
|
2010-07-08 |
2018-07-03 |
Wellesley Pharmaceuticals, Llc |
Pharmaceutical formulation for reducing frequency of urination and method of use thereof
|
US20180264013A1
(en)
*
|
2010-07-08 |
2018-09-20 |
Wellesley Pharmaceuticals, Llc |
Composition and methods for treating sleep disorders
|
US9532959B2
(en)
|
2010-07-08 |
2017-01-03 |
Wellesley Pharmaceuticals, Llc |
Pharmaceutical formulation for reducing frequency of urination and method of use thereof
|
US8858963B1
(en)
|
2011-05-17 |
2014-10-14 |
Mallinckrodt Llc |
Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
|
US8741885B1
(en)
|
2011-05-17 |
2014-06-03 |
Mallinckrodt Llc |
Gastric retentive extended release pharmaceutical compositions
|
US9050335B1
(en)
|
2011-05-17 |
2015-06-09 |
Mallinckrodt Llc |
Pharmaceutical compositions for extended release of oxycodone and acetaminophen resulting in a quick onset and prolonged period of analgesia
|
US10702485B2
(en)
|
2011-07-09 |
2020-07-07 |
Syntrix Biosystems Inc. |
Compositions and methods for overcoming resistance to tramadol
|
US10278925B2
(en)
|
2012-01-04 |
2019-05-07 |
Wellesley Pharmaceuticals, Llc |
Delayed-release formulations, methods of making and use thereof
|
US10105330B2
(en)
|
2012-01-04 |
2018-10-23 |
Wellesley Pharmaceuticals, Llc |
Extended, delayed and immediate release formulation method of manufacturing and use thereof
|
SG11201500407XA
(en)
*
|
2012-01-04 |
2015-03-30 |
Wellesley Pharmaceuticals Llc |
Extended-release formulation for reducing the frequency of urination and method of use thereof
|
JP2015506359A
(ja)
*
|
2012-01-04 |
2015-03-02 |
ウェルズリー ファーマスーティカルズ、エルエルシー |
排尿頻度を減少させるための遅延放出製剤およびその使用の方法
|
ZA201300398B
(en)
|
2012-11-27 |
2013-09-25 |
Genfarma Laboratories S L |
Injectable liquid formulation of the combination of tramadol and paracetamol
|
UA116567C2
(uk)
|
2013-07-23 |
2018-04-10 |
Євро-Селтік С.А. |
Комбінація оксикодону та налоксону для застосування в лікуванні болю у пацієнтів, які страждають від болю та захворювання, що призводить до дисбактеріозу кишечнику та/або підвищує ризик кишкової бактеріальної транслокації
|
HRP20220112T1
(hr)
|
2013-12-24 |
2022-04-15 |
Virginia Commonwealth University |
Upotreba oksidacijskog sulfata kolesterola (ocs) za liječenje akutne insuficijencije jetre
|
US10105328B2
(en)
|
2014-06-06 |
2018-10-23 |
Wellesley Pharmaceuticals, Llc |
Composition for reducing frequency of urination, method of making and use thereof
|
US9693949B1
(en)
*
|
2015-12-22 |
2017-07-04 |
Revogenex Ireland Ltd |
Intravenous administration of tramadol
|
CA3055170A1
(fr)
|
2016-03-04 |
2017-09-08 |
Charleston Laboratories, Inc. |
Compositions pharmaceutiques
|
TWI620577B
(zh)
*
|
2016-11-23 |
2018-04-11 |
|
乙醯胺酚及曲馬多共溶複方止痛口服液
|
US10781163B2
(en)
|
2017-09-18 |
2020-09-22 |
R L Finechem Private Limited |
Process for preparation of O-Desmethyltramadol and salts thereof
|
KR20190038027A
(ko)
|
2017-09-29 |
2019-04-08 |
한미약품 주식회사 |
아세트아미노펜, 및 트라마돌 또는 이의 약학적 허용 가능한 염을 포함하는 연질캡슐 조성물
|
US11000488B2
(en)
|
2019-03-22 |
2021-05-11 |
Syntrix Biosystems Inc. |
Treating pain using desmetramadol
|