US5478577A
(en)
*
|
1993-11-23 |
1995-12-26 |
Euroceltique, S.A. |
Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
|
US5958459A
(en)
*
|
1991-12-24 |
1999-09-28 |
Purdue Pharma L.P. |
Opioid formulations having extended controlled released
|
US5968551A
(en)
|
1991-12-24 |
1999-10-19 |
Purdue Pharma L.P. |
Orally administrable opioid formulations having extended duration of effect
|
US5965161A
(en)
*
|
1994-11-04 |
1999-10-12 |
Euro-Celtique, S.A. |
Extruded multi-particulates
|
US5840731A
(en)
*
|
1995-08-02 |
1998-11-24 |
Virginia Commonwealth University |
Pain-alleviating drug composition and method for alleviating pain
|
US6017963A
(en)
*
|
1995-11-14 |
2000-01-25 |
Euro-Celtique, S.A. |
Formulation for intranasal administration
|
DE19601744C2
(de)
|
1996-01-19 |
1998-04-16 |
Gruenenthal Gmbh |
Verfahren zur Herstellung der Enantiomeren von O-Demethyltramadol
|
ZA975444B
(en)
*
|
1996-06-20 |
1998-12-21 |
Mcneil Ppc Inc |
Acetaminophen and meclizine hydrochloride analgesics
|
WO1998058637A1
(en)
*
|
1996-06-20 |
1998-12-30 |
Mcneil-Ppc |
Acetaminophen and diphenhydramine analgesics
|
DE19641576C1
(de)
*
|
1996-10-09 |
1998-05-07 |
Gruenenthal Gmbh |
Kombinationspräparat enthaltend Tramadol und einen Calcium-Kanal Antagonisten
|
US5919826A
(en)
*
|
1996-10-24 |
1999-07-06 |
Algos Pharmaceutical Corporation |
Method of alleviating pain
|
US6090856A
(en)
*
|
1997-04-11 |
2000-07-18 |
Nippon Shinyaku Co., Ltd. |
Remedies for frequent urination and urinary incontinence
|
CA2295884A1
(en)
|
1997-07-15 |
1999-01-28 |
Russinsky Limited |
Tramadol, salts thereof and process for their preparation
|
US6375957B1
(en)
|
1997-12-22 |
2002-04-23 |
Euro-Celtique, S.A. |
Opioid agonist/opioid antagonist/acetaminophen combinations
|
JP2001526228A
(ja)
*
|
1997-12-22 |
2001-12-18 |
ユーロ−セルティーク,エス.エイ. |
オピオイド作動薬/拮抗薬の併用
|
US6320214B1
(en)
*
|
1997-12-24 |
2001-11-20 |
Matsushita Electric Industrial Co., Ltd. |
Semiconductor device having a ferroelectric TFT and a dummy element
|
US6156342A
(en)
*
|
1998-05-26 |
2000-12-05 |
Andex Pharmaceuticals, Inc. |
Controlled release oral dosage form
|
ATE284223T1
(de)
*
|
1999-08-20 |
2004-12-15 |
Ortho Mcneil Pharm Inc |
Zusammensetzung enthaltend ein tramadol und ein antikonvulsives arzneimittel
|
PE20010623A1
(es)
|
1999-10-05 |
2001-07-07 |
Gruenenthal Chemie |
Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria
|
US10179130B2
(en)
|
1999-10-29 |
2019-01-15 |
Purdue Pharma L.P. |
Controlled release hydrocodone formulations
|
JP4806507B2
(ja)
|
1999-10-29 |
2011-11-02 |
ユーロ−セルティーク エス.エイ. |
制御放出ヒドロコドン処方
|
AU1164601A
(en)
*
|
1999-11-09 |
2001-06-06 |
Darwin Discovery Limited |
Therapeutic use and formulation
|
AP1665A
(en)
|
2000-02-08 |
2006-09-22 |
Euro Celtique Sa |
Tamper-resistant oral opioid agonist formulations.
|
WO2001064202A2
(en)
*
|
2000-03-01 |
2001-09-07 |
Euro-Celtique S.A. |
Tramadol for the treatment of functional gastrointestinal disorders
|
CN101317825A
(zh)
|
2000-10-30 |
2008-12-10 |
欧罗赛铁克股份有限公司 |
控释氢可酮制剂
|
DE10059020A1
(de)
*
|
2000-11-28 |
2002-05-29 |
Gruenenthal Gmbh |
Parenteral applizierbare Darreichungsformen
|
US6974839B2
(en)
|
2001-03-16 |
2005-12-13 |
Dmi Biosciences, Inc. |
Method of delaying ejaculation
|
US20110104214A1
(en)
|
2004-04-15 |
2011-05-05 |
Purdue Pharma L.P. |
Once-a-day oxycodone formulations
|
CN1525851A
(zh)
|
2001-05-11 |
2004-09-01 |
������ҩ������˾ |
抗滥用阿片样物质控释剂型
|
WO2003007802A2
(en)
|
2001-07-18 |
2003-01-30 |
Euro-Celtique, S.A. |
Pharmaceutical combinations of oxycodone and naloxone
|
US20030044458A1
(en)
|
2001-08-06 |
2003-03-06 |
Curtis Wright |
Oral dosage form comprising a therapeutic agent and an adverse-effect agent
|
US20030157168A1
(en)
|
2001-08-06 |
2003-08-21 |
Christopher Breder |
Sequestered antagonist formulations
|
IL160222A0
(en)
|
2001-08-06 |
2004-07-25 |
Euro Celtique Sa |
Opioid agonist formulations with releasable and sequestered antagonist
|
SI2425825T1
(sl)
|
2002-04-05 |
2017-05-31 |
Mundipharma Medical Cee Gmbh |
Farmacevtski pripravek, ki vsebuje oksikodon in nalokson
|
EP1364649A1
(de)
*
|
2002-05-23 |
2003-11-26 |
Cilag AG |
Topirimat-Tramadol Addukt und seine Verwendung
|
US7815934B2
(en)
|
2002-09-20 |
2010-10-19 |
Alpharma Pharmaceuticals, Llc |
Sequestering subunit and related compositions and methods
|
EP1555022B1
(de)
*
|
2002-09-21 |
2008-02-20 |
Shuyi Zhang |
Formulierung von acetaminophen und tramadol mit verzögerter freisetzung
|
US20090162431A1
(en)
*
|
2002-09-21 |
2009-06-25 |
Shuyi Zhang |
Sustained release formulations containing acetaminophen and tramadol
|
TWI319713B
(en)
|
2002-10-25 |
2010-01-21 |
|
Sustained-release tramadol formulations with 24-hour efficacy
|
US8487002B2
(en)
|
2002-10-25 |
2013-07-16 |
Paladin Labs Inc. |
Controlled-release compositions
|
US6864271B2
(en)
*
|
2002-11-12 |
2005-03-08 |
The Foundation For The Lsu Health Sciences Center |
Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives
|
CA2506807A1
(en)
*
|
2002-12-13 |
2004-07-01 |
Cilag Ag |
Controlled release preparations comprising tramadol and topiramate
|
US20040202717A1
(en)
|
2003-04-08 |
2004-10-14 |
Mehta Atul M. |
Abuse-resistant oral dosage forms and method of use thereof
|
TWI347201B
(en)
|
2003-04-21 |
2011-08-21 |
Euro Celtique Sa |
Pharmaceutical products,uses thereof and methods for preparing the same
|
US20050065172A1
(en)
*
|
2003-09-23 |
2005-03-24 |
Shah Indukumar G. |
Solid dosage form comprising caffeine
|
US20050067163A1
(en)
*
|
2003-09-25 |
2005-03-31 |
George Flint R. |
Monobore release for tubing conveyed perforating
|
US20060172006A1
(en)
*
|
2003-10-10 |
2006-08-03 |
Vincent Lenaerts |
Sustained-release tramadol formulations with 24-hour clinical efficacy
|
EP1604666A1
(de)
|
2004-06-08 |
2005-12-14 |
Euro-Celtique S.A. |
Opioide zur Behandlung der chronischen obstruktiven Lungenkrankheit
|
CA2576652A1
(en)
*
|
2004-08-12 |
2006-02-16 |
Reckitt Benckiser Healthcare (Uk) Limited |
Granules comprising paracetamol, a nsaid and a sugar alcohol made by melt extrusion
|
CN100348180C
(zh)
*
|
2004-12-24 |
2007-11-14 |
河南大学 |
盐酸曲马多口腔崩解片剂及其制备方法
|
EP1702558A1
(de)
|
2005-02-28 |
2006-09-20 |
Euro-Celtique S.A. |
Verfahren und Vorrichtung zur Darmtätigkeitserfassung
|
WO2007008752A2
(en)
|
2005-07-07 |
2007-01-18 |
Farnam Companies, Inc. |
Sustained release pharmaceutical compositions for highly water soluble drugs
|
ES2389666T3
(es)
|
2005-09-09 |
2012-10-30 |
Angelini Labopharm, Llc |
Composición de trazodona para una administración de una vez al día
|
PT2719378T
(pt)
|
2006-06-19 |
2016-11-02 |
Alpharma Pharmaceuticals Llc |
Composições farmacêuticas
|
US7645767B2
(en)
*
|
2006-08-31 |
2010-01-12 |
Trinity Laboratories, Inc. |
Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
|
CA2665841C
(en)
|
2006-10-09 |
2016-04-05 |
Charleston Laboratories, Inc. |
Pharmaceutical compositions
|
DE102006056458A1
(de)
*
|
2006-11-28 |
2008-05-29 |
Grünenthal GmbH |
Arzneimittelzubereitung von Tramadol und Acetaminophen
|
WO2008100933A2
(en)
|
2007-02-12 |
2008-08-21 |
Dmi Biosciences, Inc. |
Reducing side effects of tramadol
|
DK2120570T3
(da)
*
|
2007-02-12 |
2012-06-25 |
Dmi Biosciences Inc |
Behandling af præmatur komorbid ejakulation og erektil dysfunktion
|
US20080026054A1
(en)
*
|
2007-04-27 |
2008-01-31 |
Nectid Inc. |
Novel anelgesic combination
|
US20080031950A1
(en)
*
|
2007-04-27 |
2008-02-07 |
Nectid Inc. |
Novel anelgesic combination
|
US20090028873A1
(en)
*
|
2007-07-27 |
2009-01-29 |
Auspex Pharmaceuticals, Inc. |
Substituted cyclohexanols
|
US8895066B2
(en)
*
|
2007-10-16 |
2014-11-25 |
Paladin Labs Inc. |
Bilayer composition for the sustained release of acetaminophen and tramadol
|
CA2705733C
(en)
|
2007-11-13 |
2015-02-03 |
Cadence Pharmaceuticals |
Reduced dose intravenous acetaminophen
|
US8623418B2
(en)
|
2007-12-17 |
2014-01-07 |
Alpharma Pharmaceuticals Llc |
Pharmaceutical composition
|
CN101969930A
(zh)
|
2007-12-17 |
2011-02-09 |
莱博法姆公司 |
防滥用控制释放制剂
|
WO2009089494A2
(en)
|
2008-01-09 |
2009-07-16 |
Charleston Laboratories, Inc. |
Pharmaceutical compositions
|
US8372432B2
(en)
|
2008-03-11 |
2013-02-12 |
Depomed, Inc. |
Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic
|
JP5607550B2
(ja)
|
2008-03-11 |
2014-10-15 |
ディポメド,インコーポレイティド |
非オピオイド鎮痛剤及びオピオイド鎮痛剤の組合せを含む胃保持性持続放出剤形
|
US20100003322A1
(en)
*
|
2008-07-03 |
2010-01-07 |
Lai Felix S |
Enteric coated hydrophobic matrix formulation
|
KR20110059634A
(ko)
*
|
2008-09-05 |
2011-06-02 |
그뤼넨탈 게엠베하 |
6-디메틸아미노메틸-1-(3-메톡시-페닐)-사이클로헥산-1,3디올 및 파라세타몰을 포함하는 약제학적 병용물
|
EP2177215A1
(de)
|
2008-10-17 |
2010-04-21 |
Laboratorios Del. Dr. Esteve, S.A. |
Co-Kristalle von Tramadol und NSARs
|
EA023149B1
(ru)
*
|
2008-10-27 |
2016-04-29 |
Алза Корпорейшн |
Фармацевтическая композиция, содержащая ацетаминофен и комплекс трамадола с каррагинаном, лекарственная форма, способ ее изготовления и применение комплекса трамадола с каррагинаном для лечения боли
|
WO2010069050A1
(en)
|
2008-12-16 |
2010-06-24 |
Labopharm Inc. |
Misuse preventative, controlled release formulation
|
SG174286A1
(en)
|
2009-03-10 |
2011-10-28 |
Euro Celtique Sa |
Immediate release pharmaceutical compositions comprising oxycodone and naloxone
|
CA2767576C
(en)
|
2009-07-08 |
2020-03-10 |
Charleston Laboratories Inc. |
Pharmaceutical compositions comprising an antiemetic and an opioid analgesic
|
ES2353541B1
(es)
|
2009-07-30 |
2011-09-20 |
Farmalider, S.A. |
Combinacion de ingredientes activos cosmeticos y composicion cosmetica obtenida a partir de la misma, y su utilizacion.
|
EP2281558A1
(de)
*
|
2009-08-06 |
2011-02-09 |
Laboratorios Del. Dr. Esteve, S.A. |
Pharmazeutische Verbindungen von O-Desmethyltramadol und COX-Inhibitoren
|
US20110104272A1
(en)
*
|
2009-11-05 |
2011-05-05 |
Depomed, Inc. |
Gastric retentive extended-release dosage forms comprising combinations of acetaminophen and phenylephrine
|
US8597681B2
(en)
|
2009-12-22 |
2013-12-03 |
Mallinckrodt Llc |
Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
|
US9198861B2
(en)
|
2009-12-22 |
2015-12-01 |
Mallinckrodt Llc |
Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
|
DE202010001237U1
(de)
|
2010-01-21 |
2010-04-01 |
Grünenthal GmbH |
Kombination aus Tramadol und Acetaminophen als Brausetablette
|
EP2377514A3
(de)
*
|
2010-04-19 |
2012-04-11 |
Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. |
Flüssige parenterale Formulierung, die eine Tramadolsubstanz und Paracetamol umfasst
|
GR1007315B
(el)
*
|
2010-04-19 |
2011-06-14 |
Uni-Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Abee, |
Υγρομορφη παρεντερικης χορηγησης συνθεση που περιλαμβανει τραμαδολη hci και παρακεταμολη
|
US10010514B2
(en)
|
2010-07-08 |
2018-07-03 |
Wellesley Pharmaceuticals, Llc |
Pharmaceutical formulation for reducing frequency of urination and method of use thereof
|
US20180264013A1
(en)
*
|
2010-07-08 |
2018-09-20 |
Wellesley Pharmaceuticals, Llc |
Composition and methods for treating sleep disorders
|
US9532959B2
(en)
|
2010-07-08 |
2017-01-03 |
Wellesley Pharmaceuticals, Llc |
Pharmaceutical formulation for reducing frequency of urination and method of use thereof
|
US8741885B1
(en)
|
2011-05-17 |
2014-06-03 |
Mallinckrodt Llc |
Gastric retentive extended release pharmaceutical compositions
|
US9050335B1
(en)
|
2011-05-17 |
2015-06-09 |
Mallinckrodt Llc |
Pharmaceutical compositions for extended release of oxycodone and acetaminophen resulting in a quick onset and prolonged period of analgesia
|
US8858963B1
(en)
|
2011-05-17 |
2014-10-14 |
Mallinckrodt Llc |
Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
|
US10702485B2
(en)
|
2011-07-09 |
2020-07-07 |
Syntrix Biosystems Inc. |
Compositions and methods for overcoming resistance to tramadol
|
KR20190049928A
(ko)
*
|
2012-01-04 |
2019-05-09 |
웰즐리 파마슈티컬스 엘엘씨 |
배뇨 빈도를 감소시키기 위한 서방형 제제 및 이의 사용 방법
|
US10105330B2
(en)
|
2012-01-04 |
2018-10-23 |
Wellesley Pharmaceuticals, Llc |
Extended, delayed and immediate release formulation method of manufacturing and use thereof
|
MX2014008283A
(es)
*
|
2012-01-04 |
2015-03-03 |
Wellesley Pharmaceutical Llc |
Formulacion de liberacion prolongada para reducir la frecuencia de orinar y metodos de uso de esta.
|
US10278925B2
(en)
|
2012-01-04 |
2019-05-07 |
Wellesley Pharmaceuticals, Llc |
Delayed-release formulations, methods of making and use thereof
|
ZA201300398B
(en)
|
2012-11-27 |
2013-09-25 |
Genfarma Laboratories S L |
Injectable liquid formulation of the combination of tramadol and paracetamol
|
NZ716267A
(en)
|
2013-07-23 |
2017-05-26 |
Euro Celtique Sa |
A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
|
MX2021011641A
(es)
|
2013-12-24 |
2023-03-10 |
Durect Corp |
Usos de sulfatos de colesterol oxigenados (soc).
|
US10105328B2
(en)
|
2014-06-06 |
2018-10-23 |
Wellesley Pharmaceuticals, Llc |
Composition for reducing frequency of urination, method of making and use thereof
|
US9693949B1
(en)
*
|
2015-12-22 |
2017-07-04 |
Revogenex Ireland Ltd |
Intravenous administration of tramadol
|
JP2019507181A
(ja)
|
2016-03-04 |
2019-03-14 |
チャールストン ラボラトリーズ,インコーポレイテッド |
医薬組成物
|
TWI620577B
(zh)
*
|
2016-11-23 |
2018-04-11 |
|
乙醯胺酚及曲馬多共溶複方止痛口服液
|
US10781163B2
(en)
|
2017-09-18 |
2020-09-22 |
R L Finechem Private Limited |
Process for preparation of O-Desmethyltramadol and salts thereof
|
KR20190038027A
(ko)
|
2017-09-29 |
2019-04-08 |
한미약품 주식회사 |
아세트아미노펜, 및 트라마돌 또는 이의 약학적 허용 가능한 염을 포함하는 연질캡슐 조성물
|
US11000488B2
(en)
|
2019-03-22 |
2021-05-11 |
Syntrix Biosystems Inc. |
Treating pain using desmetramadol
|