US5958459A
(en)
*
|
1991-12-24 |
1999-09-28 |
Purdue Pharma L.P. |
Opioid formulations having extended controlled released
|
US5968551A
(en)
*
|
1991-12-24 |
1999-10-19 |
Purdue Pharma L.P. |
Orally administrable opioid formulations having extended duration of effect
|
US5478577A
(en)
*
|
1993-11-23 |
1995-12-26 |
Euroceltique, S.A. |
Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
|
US5965161A
(en)
*
|
1994-11-04 |
1999-10-12 |
Euro-Celtique, S.A. |
Extruded multi-particulates
|
US5840731A
(en)
*
|
1995-08-02 |
1998-11-24 |
Virginia Commonwealth University |
Pain-alleviating drug composition and method for alleviating pain
|
US6017963A
(en)
|
1995-11-14 |
2000-01-25 |
Euro-Celtique, S.A. |
Formulation for intranasal administration
|
DE19601744C2
(de)
*
|
1996-01-19 |
1998-04-16 |
Gruenenthal Gmbh |
Verfahren zur Herstellung der Enantiomeren von O-Demethyltramadol
|
WO1998058637A1
(fr)
*
|
1996-06-20 |
1998-12-30 |
Mcneil-Ppc |
Analgesique a base d'acetaminophene et de diphenhydramine
|
ZA975444B
(en)
*
|
1996-06-20 |
1998-12-21 |
Mcneil Ppc Inc |
Acetaminophen and meclizine hydrochloride analgesics
|
DE19641576C1
(de)
*
|
1996-10-09 |
1998-05-07 |
Gruenenthal Gmbh |
Kombinationspräparat enthaltend Tramadol und einen Calcium-Kanal Antagonisten
|
US5919826A
(en)
*
|
1996-10-24 |
1999-07-06 |
Algos Pharmaceutical Corporation |
Method of alleviating pain
|
WO1998046216A1
(fr)
*
|
1997-04-11 |
1998-10-22 |
Nippon Shinyaku Co., Ltd. |
Traitements des mictions frequentes et de l'incontinence urinaire
|
IE980512A1
(en)
|
1997-07-15 |
1999-10-20 |
Russinsky Ltd |
A product and process
|
US6375957B1
(en)
|
1997-12-22 |
2002-04-23 |
Euro-Celtique, S.A. |
Opioid agonist/opioid antagonist/acetaminophen combinations
|
RS50070B
(sr)
|
1997-12-22 |
2009-01-22 |
Euro-Celtique S.A., |
Oralni dozni oblik sa kombinacijom opijatnog agonista i antagonista
|
US6320214B1
(en)
*
|
1997-12-24 |
2001-11-20 |
Matsushita Electric Industrial Co., Ltd. |
Semiconductor device having a ferroelectric TFT and a dummy element
|
US6156342A
(en)
*
|
1998-05-26 |
2000-12-05 |
Andex Pharmaceuticals, Inc. |
Controlled release oral dosage form
|
AU782759B2
(en)
*
|
1999-08-20 |
2005-08-25 |
Ortho-Mcneil Pharmaceutical, Inc. |
Composition comprising a tramadol material and an anticonvulsant drug
|
PE20010623A1
(es)
|
1999-10-05 |
2001-07-07 |
Gruenenthal Chemie |
Uso de (+)-tramadol y/o o-demetiltramadol para tratamiento de urgencia urinaria incrementada y/o incontinencia urinaria
|
US10179130B2
(en)
|
1999-10-29 |
2019-01-15 |
Purdue Pharma L.P. |
Controlled release hydrocodone formulations
|
ATE526950T1
(de)
|
1999-10-29 |
2011-10-15 |
Euro Celtique Sa |
Hydrocodon-formulierungen mit gesteuerter freisetzung
|
AU1164601A
(en)
*
|
1999-11-09 |
2001-06-06 |
Darwin Discovery Limited |
Therapeutic use and formulation
|
EP2517710B1
(fr)
|
2000-02-08 |
2015-03-25 |
Euro-Celtique S.A. |
Formules agonistes opioïdes orales inviolables
|
WO2001064202A2
(fr)
*
|
2000-03-01 |
2001-09-07 |
Euro-Celtique S.A. |
Traitement de troubles gastro-intestinaux fonctionnels
|
EP2263658A1
(fr)
|
2000-10-30 |
2010-12-22 |
Euro-Celtique S.A. |
Formulations d'hydrocodone à liberation lente
|
DE10059020A1
(de)
*
|
2000-11-28 |
2002-05-29 |
Gruenenthal Gmbh |
Parenteral applizierbare Darreichungsformen
|
EP1397126B9
(fr)
|
2001-03-16 |
2007-02-21 |
DMI Biosciences, Inc. |
Utilisation du tramadol pour retarder l'ejaculation
|
US20110104214A1
(en)
|
2004-04-15 |
2011-05-05 |
Purdue Pharma L.P. |
Once-a-day oxycodone formulations
|
CN1525851A
(zh)
|
2001-05-11 |
2004-09-01 |
������ҩ������˾ |
抗滥用阿片样物质控释剂型
|
ATE419039T1
(de)
|
2001-07-18 |
2009-01-15 |
Euro Celtique Sa |
Pharmazeutische kombinationen von oxycodon und naloxon
|
US20030044458A1
(en)
|
2001-08-06 |
2003-03-06 |
Curtis Wright |
Oral dosage form comprising a therapeutic agent and an adverse-effect agent
|
US20030157168A1
(en)
|
2001-08-06 |
2003-08-21 |
Christopher Breder |
Sequestered antagonist formulations
|
DE60232417D1
(de)
|
2001-08-06 |
2009-07-02 |
Euro Celtique Sa |
Opioid-agonist-formulierungen mit freisetzbarem und sequestriertem antagonist
|
DK2425824T5
(en)
|
2002-04-05 |
2018-02-12 |
Mundipharma As |
Pharmaceutical preparation containing oxycodone and naloxone
|
EP1364649A1
(fr)
*
|
2002-05-23 |
2003-11-26 |
Cilag AG |
Produits d'addition de tramadol et topiramate et son utilization
|
EP2422772A3
(fr)
|
2002-09-20 |
2012-04-18 |
Alpharma, Inc. |
Séquestration de sous-unité et compositions et procédés associés
|
US20090162431A1
(en)
*
|
2002-09-21 |
2009-06-25 |
Shuyi Zhang |
Sustained release formulations containing acetaminophen and tramadol
|
AU2003271024A1
(en)
*
|
2002-09-21 |
2004-04-08 |
Jin Wang |
Sustained release compound of acetamidophenol and tramadol
|
US8487002B2
(en)
|
2002-10-25 |
2013-07-16 |
Paladin Labs Inc. |
Controlled-release compositions
|
TWI319713B
(en)
|
2002-10-25 |
2010-01-21 |
|
Sustained-release tramadol formulations with 24-hour efficacy
|
US6864271B2
(en)
*
|
2002-11-12 |
2005-03-08 |
The Foundation For The Lsu Health Sciences Center |
Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives
|
BR0317177A
(pt)
*
|
2002-12-13 |
2005-10-25 |
Cilag Ag |
Preparações de liberação controlada compreendendo tramadol e topiramato
|
US20040202717A1
(en)
|
2003-04-08 |
2004-10-14 |
Mehta Atul M. |
Abuse-resistant oral dosage forms and method of use thereof
|
MY135852A
(en)
|
2003-04-21 |
2008-07-31 |
Euro Celtique Sa |
Pharmaceutical products
|
US20050065172A1
(en)
*
|
2003-09-23 |
2005-03-24 |
Shah Indukumar G. |
Solid dosage form comprising caffeine
|
US20050067163A1
(en)
*
|
2003-09-25 |
2005-03-31 |
George Flint R. |
Monobore release for tubing conveyed perforating
|
US20060172006A1
(en)
*
|
2003-10-10 |
2006-08-03 |
Vincent Lenaerts |
Sustained-release tramadol formulations with 24-hour clinical efficacy
|
EP1604666A1
(fr)
|
2004-06-08 |
2005-12-14 |
Euro-Celtique S.A. |
Opioides pour le traitement de la bronchopneumopathie chronique obstructive
|
RU2389480C2
(ru)
*
|
2004-08-12 |
2010-05-20 |
РЕКИТТ БЕНКАЙЗЕР ХЕЛТКЭА (Ю Кей) ЛИМИТЕД |
Гранулы, содержащие нпвлс и сахарный спирт, изготовленные экструзией из расплава
|
CN100348180C
(zh)
*
|
2004-12-24 |
2007-11-14 |
河南大学 |
盐酸曲马多口腔崩解片剂及其制备方法
|
EP1702558A1
(fr)
|
2005-02-28 |
2006-09-20 |
Euro-Celtique S.A. |
Procédé et dispositif pour évaluer la fonction de l'activité intestinale
|
US8221792B2
(en)
|
2005-07-07 |
2012-07-17 |
Farnam Companies, Inc. |
Sustained release pharmaceutical compositions for highly water soluble drugs
|
JP5269595B2
(ja)
|
2005-09-09 |
2013-08-21 |
アンジェリーニ ラボファーム リミテッド ライアビリティ カンパニー |
1日1回投与用トラゾドン組成物
|
KR101486228B1
(ko)
|
2006-06-19 |
2015-01-26 |
알파마 파머슈티컬스 엘엘씨 |
약제학적 조성물
|
US7645767B2
(en)
*
|
2006-08-31 |
2010-01-12 |
Trinity Laboratories, Inc. |
Pharmaceutical compositions for treating chronic pain and pain associated with neuropathy
|
SI2124556T1
(sl)
*
|
2006-10-09 |
2015-01-30 |
Charleston Laboratories, Inc. |
Farmacevtske sestave
|
DE102006056458A1
(de)
*
|
2006-11-28 |
2008-05-29 |
Grünenthal GmbH |
Arzneimittelzubereitung von Tramadol und Acetaminophen
|
AU2008216356C1
(en)
*
|
2007-02-12 |
2014-07-24 |
Aytu Bioscience, Inc. |
Treatment of comorbid premature ejaculation and erectile dysfunction
|
PL2114147T3
(pl)
*
|
2007-02-12 |
2012-10-31 |
Vyrix Pharmaceuticals Inc |
Zmniejszanie skutków ubocznych tramadolu
|
US20080031950A1
(en)
*
|
2007-04-27 |
2008-02-07 |
Nectid Inc. |
Novel anelgesic combination
|
US20080026054A1
(en)
*
|
2007-04-27 |
2008-01-31 |
Nectid Inc. |
Novel anelgesic combination
|
US20090028873A1
(en)
*
|
2007-07-27 |
2009-01-29 |
Auspex Pharmaceuticals, Inc. |
Substituted cyclohexanols
|
ES2541809T3
(es)
*
|
2007-10-16 |
2015-07-24 |
Paladin Labs Inc. |
Composición bicapa para la liberación sostenida de acetaminofeno y tramadol
|
CA2705733C
(fr)
|
2007-11-13 |
2015-02-03 |
Cadence Pharmaceuticals |
Acetaminophene par voie intraveineuse en dose reduite
|
EP2219612A4
(fr)
|
2007-12-17 |
2013-10-30 |
Paladin Labs Inc |
Formulation à libération contrôlée évitant les utilisations impropres
|
US8623418B2
(en)
|
2007-12-17 |
2014-01-07 |
Alpharma Pharmaceuticals Llc |
Pharmaceutical composition
|
EP3090743A1
(fr)
|
2008-01-09 |
2016-11-09 |
Charleston Laboratories, Inc. |
Compositions pharmaceutiques
|
EP2262484B1
(fr)
|
2008-03-11 |
2013-01-23 |
Depomed, Inc. |
Formes médicamenteuses à libération étendue de rétention gastrique comprenant des combinaisons d'un analgésique non opioïde et d'un analgésique opioïde
|
US8372432B2
(en)
|
2008-03-11 |
2013-02-12 |
Depomed, Inc. |
Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic
|
US20100003322A1
(en)
*
|
2008-07-03 |
2010-01-07 |
Lai Felix S |
Enteric coated hydrophobic matrix formulation
|
US20100069501A1
(en)
*
|
2008-09-05 |
2010-03-18 |
Gruenenthal Gmbh |
Pharmaceutical Composition Comprising 6-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol and Paracetamol
|
EP2177215A1
(fr)
|
2008-10-17 |
2010-04-21 |
Laboratorios Del. Dr. Esteve, S.A. |
Co-cristaux de tramadol et NSAID
|
JP5713911B2
(ja)
|
2008-10-27 |
2015-05-07 |
アルザ・コーポレーシヨン |
長期放出型経口アセトアミノフェン/トラマドール投与形態
|
EP2367541B1
(fr)
|
2008-12-16 |
2014-07-16 |
Paladin Labs Inc. |
Composition à libération contrôlée prévenant un mésusage
|
WO2010103039A1
(fr)
|
2009-03-10 |
2010-09-16 |
Euro-Celtique S.A. |
Compositions pharmaceutiques à libération immédiate comportant de l'oxycodone et du naloxone
|
CA2767576C
(fr)
|
2009-07-08 |
2020-03-10 |
Charleston Laboratories Inc. |
Compositions pharmaceutiques refermant un antiemetique et un analgesiqueopioide
|
ES2353541B1
(es)
|
2009-07-30 |
2011-09-20 |
Farmalider, S.A. |
Combinacion de ingredientes activos cosmeticos y composicion cosmetica obtenida a partir de la misma, y su utilizacion.
|
EP2281558A1
(fr)
*
|
2009-08-06 |
2011-02-09 |
Laboratorios Del. Dr. Esteve, S.A. |
Composés pharmaceutique de O-desméthyl-tramadol et inhibiteurs COX
|
US20110104272A1
(en)
*
|
2009-11-05 |
2011-05-05 |
Depomed, Inc. |
Gastric retentive extended-release dosage forms comprising combinations of acetaminophen and phenylephrine
|
US9198861B2
(en)
|
2009-12-22 |
2015-12-01 |
Mallinckrodt Llc |
Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
|
US8597681B2
(en)
|
2009-12-22 |
2013-12-03 |
Mallinckrodt Llc |
Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
|
DE202010001237U1
(de)
|
2010-01-21 |
2010-04-01 |
Grünenthal GmbH |
Kombination aus Tramadol und Acetaminophen als Brausetablette
|
GR1007315B
(el)
*
|
2010-04-19 |
2011-06-14 |
Uni-Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Abee, |
Υγρομορφη παρεντερικης χορηγησης συνθεση που περιλαμβανει τραμαδολη hci και παρακεταμολη
|
EP2377514A3
(fr)
*
|
2010-04-19 |
2012-04-11 |
Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. |
Formulation parentérale liquide comportant un matériau de tramadol et paracétamol
|
US9532959B2
(en)
|
2010-07-08 |
2017-01-03 |
Wellesley Pharmaceuticals, Llc |
Pharmaceutical formulation for reducing frequency of urination and method of use thereof
|
US20180264013A1
(en)
*
|
2010-07-08 |
2018-09-20 |
Wellesley Pharmaceuticals, Llc |
Composition and methods for treating sleep disorders
|
US10010514B2
(en)
|
2010-07-08 |
2018-07-03 |
Wellesley Pharmaceuticals, Llc |
Pharmaceutical formulation for reducing frequency of urination and method of use thereof
|
US8658631B1
(en)
|
2011-05-17 |
2014-02-25 |
Mallinckrodt Llc |
Combination composition comprising oxycodone and acetaminophen for rapid onset and extended duration of analgesia
|
US8858963B1
(en)
|
2011-05-17 |
2014-10-14 |
Mallinckrodt Llc |
Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
|
US8741885B1
(en)
|
2011-05-17 |
2014-06-03 |
Mallinckrodt Llc |
Gastric retentive extended release pharmaceutical compositions
|
US10702485B2
(en)
|
2011-07-09 |
2020-07-07 |
Syntrix Biosystems Inc. |
Compositions and methods for overcoming resistance to tramadol
|
JP2015503583A
(ja)
*
|
2012-01-04 |
2015-02-02 |
ウェルズリー ファーマスーティカルズ、エルエルシー |
排尿頻度を減少させるための延長放出製剤およびその使用の方法
|
KR20180023057A
(ko)
*
|
2012-01-04 |
2018-03-06 |
웰즐리 파마슈티컬스 엘엘씨 |
배뇨 빈도를 감소시키기 위한 서방형 제제 및 이의 사용 방법
|
US10278925B2
(en)
|
2012-01-04 |
2019-05-07 |
Wellesley Pharmaceuticals, Llc |
Delayed-release formulations, methods of making and use thereof
|
US10105330B2
(en)
|
2012-01-04 |
2018-10-23 |
Wellesley Pharmaceuticals, Llc |
Extended, delayed and immediate release formulation method of manufacturing and use thereof
|
ZA201300398B
(en)
|
2012-11-27 |
2013-09-25 |
Genfarma Laboratories S L |
Injectable liquid formulation of the combination of tramadol and paracetamol
|
AU2014295042B2
(en)
|
2013-07-23 |
2017-03-30 |
Mundipharma Pty Limited |
A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
|
TW202348234A
(zh)
|
2013-12-24 |
2023-12-16 |
維吉尼亞聯邦大學 |
氧化膽固醇硫酸鹽(ocs)之用途
|
US10105328B2
(en)
|
2014-06-06 |
2018-10-23 |
Wellesley Pharmaceuticals, Llc |
Composition for reducing frequency of urination, method of making and use thereof
|
US9693949B1
(en)
*
|
2015-12-22 |
2017-07-04 |
Revogenex Ireland Ltd |
Intravenous administration of tramadol
|
WO2017152130A1
(fr)
|
2016-03-04 |
2017-09-08 |
Charleston Laboratories, Inc. |
Compositions pharmaceutiques
|
TWI620577B
(zh)
*
|
2016-11-23 |
2018-04-11 |
|
乙醯胺酚及曲馬多共溶複方止痛口服液
|
EP3684753A1
(fr)
|
2017-09-18 |
2020-07-29 |
R L Fine Chem Private Limited |
Procédé de préparation de d'o-desméthyltramadol et de sels de celui-ci
|
KR20190038027A
(ko)
|
2017-09-29 |
2019-04-08 |
한미약품 주식회사 |
아세트아미노펜, 및 트라마돌 또는 이의 약학적 허용 가능한 염을 포함하는 연질캡슐 조성물
|
US11000488B2
(en)
|
2019-03-22 |
2021-05-11 |
Syntrix Biosystems Inc. |
Treating pain using desmetramadol
|