SG175078A1 - Bispecific anti-erbb-1/anti-c-met antibodies - Google Patents
Bispecific anti-erbb-1/anti-c-met antibodies Download PDFInfo
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- SG175078A1 SG175078A1 SG2011072618A SG2011072618A SG175078A1 SG 175078 A1 SG175078 A1 SG 175078A1 SG 2011072618 A SG2011072618 A SG 2011072618A SG 2011072618 A SG2011072618 A SG 2011072618A SG 175078 A1 SG175078 A1 SG 175078A1
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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Applications Claiming Priority (2)
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| EP09005109 | 2009-04-07 | ||
| PCT/EP2010/002003 WO2010115551A1 (en) | 2009-04-07 | 2010-03-30 | Bispecific anti-erbb-1/anti-c-met antibodies |
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| SG175078A1 true SG175078A1 (en) | 2011-11-28 |
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| SG2011072634A SG175080A1 (en) | 2009-04-07 | 2010-03-30 | Bispecific anti-erbb-2/anti-c-met antibodies |
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| SG2011072634A SG175080A1 (en) | 2009-04-07 | 2010-03-30 | Bispecific anti-erbb-2/anti-c-met antibodies |
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| US (4) | US20100254988A1 (OSRAM) |
| EP (2) | EP2417160A1 (OSRAM) |
| JP (2) | JP5612663B2 (OSRAM) |
| KR (2) | KR20110126748A (OSRAM) |
| CN (2) | CN102361884A (OSRAM) |
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| MX (2) | MX2011010169A (OSRAM) |
| SG (2) | SG175078A1 (OSRAM) |
| TW (2) | TW201039849A (OSRAM) |
| WO (2) | WO2010115551A1 (OSRAM) |
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| US9266967B2 (en) | 2007-12-21 | 2016-02-23 | Hoffmann-La Roche, Inc. | Bivalent, bispecific antibodies |
| US20090162359A1 (en) | 2007-12-21 | 2009-06-25 | Christian Klein | Bivalent, bispecific antibodies |
| CN102014913A (zh) * | 2008-03-06 | 2011-04-13 | 健泰科生物技术公司 | C-met和egfr拮抗剂的联合疗法 |
| CA2756244A1 (en) | 2009-04-02 | 2010-10-07 | Roche Glycart Ag | Multispecific antibodies comprising full length antibodies and single chain fab fragments |
| ES2537100T3 (es) | 2009-04-07 | 2015-06-02 | Roche Glycart Ag | Anticuerpos biespecíficos trivalentes |
| US9676845B2 (en) | 2009-06-16 | 2017-06-13 | Hoffmann-La Roche, Inc. | Bispecific antigen binding proteins |
| US9493578B2 (en) | 2009-09-02 | 2016-11-15 | Xencor, Inc. | Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens |
| AU2010296018B2 (en) | 2009-09-16 | 2016-05-05 | Genentech, Inc. | Coiled coil and/or tether containing protein complexes and uses thereof |
| AR080793A1 (es) | 2010-03-26 | 2012-05-09 | Roche Glycart Ag | Anticuerpos biespecificos |
| CN105585630B (zh) | 2010-07-29 | 2020-09-15 | Xencor公司 | 具有修改的等电点的抗体 |
| CA3250882A1 (en) * | 2010-08-02 | 2025-11-29 | Regeneron Pharamaceuticals, Inc. | Mice that Make Binding Proteins Comprising VL Domains |
| EP2609111B1 (en) | 2010-08-24 | 2017-11-01 | F. Hoffmann-La Roche AG | Bispecific antibodies comprising a disulfide stabilized-fv fragment |
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| CA2757426A1 (en) | 2010-10-14 |
| WO2010115551A1 (en) | 2010-10-14 |
| BRPI1014474A2 (pt) | 2017-06-27 |
| CN102361884A (zh) | 2012-02-22 |
| WO2010115553A1 (en) | 2010-10-14 |
| US20130156772A1 (en) | 2013-06-20 |
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| US20100254989A1 (en) | 2010-10-07 |
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| CN102361883A (zh) | 2012-02-22 |
| BRPI1014449A2 (pt) | 2017-06-27 |
| US20100254988A1 (en) | 2010-10-07 |
| KR20110126748A (ko) | 2011-11-23 |
| MX2011010158A (es) | 2011-10-17 |
| JP5612663B2 (ja) | 2014-10-22 |
| JP2012522523A (ja) | 2012-09-27 |
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