SG11201706774WA - Chimeric antigen receptors (cars) targeting hematologic malignancies, compositions and methods of use thereof - Google Patents
Chimeric antigen receptors (cars) targeting hematologic malignancies, compositions and methods of use thereofInfo
- Publication number
- SG11201706774WA SG11201706774WA SG11201706774WA SG11201706774WA SG11201706774WA SG 11201706774W A SG11201706774W A SG 11201706774WA SG 11201706774W A SG11201706774W A SG 11201706774WA SG 11201706774W A SG11201706774W A SG 11201706774WA SG 11201706774W A SG11201706774W A SG 11201706774WA
- Authority
- SG
- Singapore
- Prior art keywords
- cars
- compositions
- methods
- chimeric antigen
- antigen receptors
- Prior art date
Links
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 title 1
- 208000002250 Hematologic Neoplasms Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000008685 targeting Effects 0.000 title 1
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/53—CD2
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- C12N2740/00—Reverse transcribing RNA viruses
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- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US201562121842P | 2015-02-27 | 2015-02-27 | |
PCT/US2016/019953 WO2016138491A1 (fr) | 2015-02-27 | 2016-02-26 | Récepteurs d'antigène chimériques (car) ciblant des tumeurs malignes hématologiques, compositions et procédés pour les utiliser |
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SG11201706774WA true SG11201706774WA (en) | 2017-09-28 |
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SG11201706774WA SG11201706774WA (en) | 2015-02-27 | 2016-02-26 | Chimeric antigen receptors (cars) targeting hematologic malignancies, compositions and methods of use thereof |
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US (3) | US10273280B2 (fr) |
EP (2) | EP4091616A1 (fr) |
JP (2) | JP7237449B2 (fr) |
KR (2) | KR102632082B1 (fr) |
CN (3) | CN114230670A (fr) |
AU (1) | AU2016225012B2 (fr) |
CA (1) | CA2977106A1 (fr) |
ES (1) | ES2923895T3 (fr) |
IL (1) | IL254141B (fr) |
PL (1) | PL3261651T3 (fr) |
SG (1) | SG11201706774WA (fr) |
TW (2) | TW202143986A (fr) |
WO (2) | WO2016138491A1 (fr) |
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WO2014145252A2 (fr) | 2013-03-15 | 2014-09-18 | Milone Michael C | Ciblage de cellules cytotoxiques par des récepteurs chimériques pour une immunothérapie adoptive |
CN104087607B (zh) * | 2013-04-01 | 2017-06-20 | 科济生物医药(上海)有限公司 | 编码嵌合抗原受体蛋白的核酸及表达嵌合抗原受体蛋白的t淋巴细胞 |
MX2015015662A (es) | 2013-05-13 | 2016-09-16 | Cellectis | Receptor quimérico de antígeno especifico para cd19 y sus usos. |
AU2014343636A1 (en) | 2013-11-04 | 2016-06-02 | Glenmark Pharmaceuticals S.A. | Production of T cell retargeting hetero-dimeric immunoglobulins |
EP3858379A1 (fr) | 2013-11-21 | 2021-08-04 | Autolus Limited | Cellule |
EP3102236A4 (fr) | 2014-02-05 | 2017-08-30 | The University of Chicago | Récepteurs antigéniques chimériques reconnaissant des variants de glycopeptides tn spécifiques du cancer |
EP3105317B1 (fr) | 2014-02-14 | 2018-09-19 | Cellectis | Cellules destinées à l'immunothérapie modifiées pour cibler un antigène présent à la fois sur les cellules immunitaires et les cellules pathologiques |
SG10201808825XA (en) | 2014-04-10 | 2018-11-29 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Defined composition gene modified t-cell products |
EP3166968B1 (fr) | 2014-05-02 | 2021-09-22 | The Trustees of the University of Pennsylvania | Compositions de récepteurs d'auto-anticorps chimériques et procédés afférents |
GB2541599B (en) | 2014-05-14 | 2020-05-20 | Carsgen Therapeutics Ltd | Nucleic acid for coding chimeric antigen receptor protein and T lymphocyte for expression of chimeric antigen receptor protein |
CN104004092B (zh) * | 2014-06-05 | 2015-07-29 | 深圳市第三人民医院 | 单基因编码的双或多价特异性抗hiv免疫粘附素 |
WO2016014553A1 (fr) | 2014-07-21 | 2016-01-28 | Novartis Ag | Récepteurs d'antigènes chimères synthétisés par l'intermédiaire d'une sortase |
US10765699B2 (en) | 2015-02-06 | 2020-09-08 | National University Of Singapore | Methods for enhancing efficacy of therapeutic immune cells |
KR102632082B1 (ko) * | 2015-02-27 | 2024-02-02 | 아이셀 진 테라퓨틱스 엘엘씨 | 혈액 악성종양을 표적으로 하는 키메라 항원 수용체(car), 조성물 및 이의 용도 |
EP3286225B1 (fr) * | 2015-04-23 | 2020-07-01 | Baylor College of Medicine | Récepteur antigénique chimérique ciblant le cd5 pour une thérapie adoptive à base de cellules t |
-
2016
- 2016-02-26 KR KR1020177027386A patent/KR102632082B1/ko active IP Right Grant
- 2016-02-26 ES ES16756524T patent/ES2923895T3/es active Active
- 2016-02-26 CA CA2977106A patent/CA2977106A1/fr active Pending
- 2016-02-26 EP EP22171209.4A patent/EP4091616A1/fr active Pending
- 2016-02-26 SG SG11201706774WA patent/SG11201706774WA/en unknown
- 2016-02-26 EP EP16756524.1A patent/EP3261651B1/fr active Active
- 2016-02-26 KR KR1020247003304A patent/KR102678631B1/ko active IP Right Grant
- 2016-02-26 JP JP2017564321A patent/JP7237449B2/ja active Active
- 2016-02-26 WO PCT/US2016/019953 patent/WO2016138491A1/fr active Application Filing
- 2016-02-26 PL PL16756524.1T patent/PL3261651T3/pl unknown
- 2016-02-26 CN CN202111206050.1A patent/CN114230670A/zh active Pending
- 2016-02-26 AU AU2016225012A patent/AU2016225012B2/en active Active
- 2016-02-26 IL IL254141A patent/IL254141B/en unknown
- 2016-02-26 CN CN201680011435.3A patent/CN107249602B/zh active Active
- 2016-02-26 US US15/551,862 patent/US10273280B2/en active Active
- 2016-03-01 TW TW110126850A patent/TW202143986A/zh unknown
- 2016-03-01 TW TW105106256A patent/TWI823829B/zh active
- 2016-07-15 CN CN201680082302.5A patent/CN109414428A/zh active Pending
- 2016-07-15 WO PCT/US2016/042591 patent/WO2017146767A1/fr active Application Filing
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2019
- 2019-04-01 US US16/371,501 patent/US20190345217A1/en not_active Abandoned
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2021
- 2021-02-19 JP JP2021025246A patent/JP7379399B2/ja active Active
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2023
- 2023-03-14 US US18/121,101 patent/US20240124547A1/en active Pending
Also Published As
Publication number | Publication date |
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TW202143986A (zh) | 2021-12-01 |
US20240124547A1 (en) | 2024-04-18 |
CA2977106A1 (fr) | 2016-09-01 |
KR102632082B1 (ko) | 2024-02-02 |
AU2016225012A1 (en) | 2017-08-31 |
EP3261651A1 (fr) | 2018-01-03 |
PL3261651T3 (pl) | 2022-08-22 |
TW201706295A (zh) | 2017-02-16 |
US20190345217A1 (en) | 2019-11-14 |
JP7237449B2 (ja) | 2023-03-13 |
CN107249602A (zh) | 2017-10-13 |
IL254141A0 (en) | 2017-10-31 |
WO2017146767A1 (fr) | 2017-08-31 |
IL254141B (en) | 2022-07-01 |
JP2018513692A (ja) | 2018-05-31 |
EP4091616A1 (fr) | 2022-11-23 |
JP7379399B2 (ja) | 2023-11-14 |
CN107249602B (zh) | 2021-09-28 |
CN109414428A (zh) | 2019-03-01 |
KR20180002604A (ko) | 2018-01-08 |
EP3261651A4 (fr) | 2018-11-07 |
CN114230670A (zh) | 2022-03-25 |
ES2923895T3 (es) | 2022-10-03 |
AU2016225012B2 (en) | 2020-09-03 |
US10273280B2 (en) | 2019-04-30 |
JP2021078514A (ja) | 2021-05-27 |
TWI823829B (zh) | 2023-12-01 |
KR20240018680A (ko) | 2024-02-13 |
WO2016138491A1 (fr) | 2016-09-01 |
US20180066034A1 (en) | 2018-03-08 |
KR102678631B1 (ko) | 2024-06-28 |
EP3261651B1 (fr) | 2022-05-04 |
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