CA2297294C
(en)
|
1989-05-15 |
2005-11-08 |
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic |
Phosphonomethoxymethylpurine/pyrimidine derivatives
|
IT1249732B
(it)
|
1991-11-26 |
1995-03-09 |
Angeletti P Ist Richerche Bio |
Oligonucleotidi antisenso.
|
US5977061A
(en)
|
1995-04-21 |
1999-11-02 |
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic |
N6 - substituted nucleotide analagues and their use
|
CZ126799A3
(cs)
|
1996-10-16 |
1999-07-14 |
Icn Pharmaceuticals |
Purinové L-nukleosidy a jejich analogy a farmaceutické prostředky, které je obsahují
|
ZA986614B
(en)
|
1997-07-25 |
1999-01-27 |
Gilead Sciences |
Nucleotide analog composition
|
BR9908270A
(pt)
|
1998-02-25 |
2004-06-29 |
Univ Emory |
2-fluoro-nucleosìdeos, composições farmacêuticas e seus usos
|
IN191496B
(ko)
*
|
1999-07-30 |
2003-12-06 |
Ranbaxy Lab Ltd |
|
ATE414520T1
(de)
|
2000-04-13 |
2008-12-15 |
Pharmasset Inc |
3 oder 2 hydroxymethyl substituierte nucleoside derivate und ihre verwendung zur behandlung von virusinfektionen
|
MY164523A
(en)
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
CZ301182B6
(cs)
|
2000-05-26 |
2009-12-02 |
Idenix (Cayman) Limited |
Použití nukleosidových derivátu pro výrobu farmaceutických prostredku pro lécení infekcí vyvolaných flaviviry a pestiviry
|
ES2402597T3
(es)
|
2000-10-18 |
2013-05-07 |
Gilead Pharmasset Llc |
Nucleósidos modificados para el tratamiento de infecciones víricas y proliferación celular anormal
|
ATE526339T1
(de)
|
2001-01-22 |
2011-10-15 |
Merck Sharp & Dohme |
Nukleosidderivate als inhibitoren der rna- abhängigen viralen rna-polymerase
|
US7105499B2
(en)
|
2001-01-22 |
2006-09-12 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
GB0112617D0
(en)
|
2001-05-23 |
2001-07-18 |
Hoffmann La Roche |
Antiviral nucleoside derivatives
|
GB0114286D0
(en)
|
2001-06-12 |
2001-08-01 |
Hoffmann La Roche |
Nucleoside Derivatives
|
BR0210594A
(pt)
|
2001-06-22 |
2005-11-01 |
Pharmasset Ltd |
(beta)-d ou (beta)-l-3-halonucleosìdeo
|
EP1435974A4
(en)
|
2001-09-28 |
2006-09-06 |
Idenix Cayman Ltd |
METHOD AND COMPOSITIONS FOR TREATING HEPATITIS C VIRUS WITH 4'-MODIFIED NUCLEOSIDES
|
GB2383042A
(en)
*
|
2001-10-18 |
2003-06-18 |
Cipla Ltd |
Amorphous alendronate sodium
|
WO2003039523A2
(en)
|
2001-11-05 |
2003-05-15 |
Exiqon A/S |
OLIGONUCLEOTIDES MODIFIED WITH NOVEL α-L-RNA ANALOGUES
|
US7388002B2
(en)
|
2001-11-14 |
2008-06-17 |
Biocryst Pharmaceuticals, Inc. |
Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases
|
KR100978904B1
(ko)
|
2001-12-14 |
2010-08-31 |
파마셋 인코포레이티드 |
바이러스 감염 치료용 n4-아실사이토신 뉴클레오사이드
|
AU2002360697B2
(en)
|
2001-12-20 |
2009-04-23 |
Beth Israel Deaconess Medical Center |
Treatment of EBV and KHSV infection and associated abnormal cellular proliferation
|
WO2003062256A1
(en)
|
2002-01-17 |
2003-07-31 |
Ribapharm Inc. |
2'-beta-modified-6-substituted adenosine analogs and their use as antiviral agents
|
CA2477741A1
(en)
|
2002-02-28 |
2003-09-04 |
Biota, Inc. |
Nucleotide mimics and their prodrugs
|
US20040063658A1
(en)
|
2002-05-06 |
2004-04-01 |
Roberts Christopher Don |
Nucleoside derivatives for treating hepatitis C virus infection
|
BR0312278A
(pt)
|
2002-06-28 |
2007-06-19 |
Idenix Cayman Ltd |
éster 2'-c-metil-3'-o-l-valina de ribofuranosil citidina para tratamento de infecções por flaviviridae
|
US7608600B2
(en)
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
WO2004009020A2
(en)
|
2002-07-24 |
2004-01-29 |
Merck & Co., Inc. |
Pyrrolopyrimidine thionucleoside analogs as antivirals
|
CA2494340C
(en)
|
2002-08-01 |
2012-01-24 |
Pharmasset Inc. |
Compounds with the bicyclo[4.2.1]nonane system for the treatment of flaviviridae infections
|
US20040067877A1
(en)
|
2002-08-01 |
2004-04-08 |
Schinazi Raymond F. |
2', 3'-Dideoxynucleoside analogues for the treatment or prevention of Flaviviridae infections
|
WO2004014312A2
(en)
|
2002-08-08 |
2004-02-19 |
Sirna Therapeutics, Inc. |
Small-mer compositions and methods of use
|
CA2506129C
(en)
|
2002-11-15 |
2015-02-17 |
Idenix (Cayman) Limited |
2'-branched nucleosides and flaviviridae mutation
|
TWI294882B
(en)
|
2002-12-09 |
2008-03-21 |
Hoffmann La Roche |
Anhydrous crystalline azido cytosine hemisulfate derivative
|
AR043006A1
(es)
|
2003-02-12 |
2005-07-13 |
Merck & Co Inc |
Proceso para preparar ribonucleosidos ramificados
|
US20050020675A1
(en)
*
|
2003-02-21 |
2005-01-27 |
Parthasaradhi Reddy Bandi |
Bicalutamide polymorphs
|
US7691603B2
(en)
|
2003-04-09 |
2010-04-06 |
Novo Nordisk A/S |
Intracellular formation of peptide conjugates
|
EP1628685B1
(en)
|
2003-04-25 |
2010-12-08 |
Gilead Sciences, Inc. |
Antiviral phosphonate analogs
|
US20040259934A1
(en)
|
2003-05-01 |
2004-12-23 |
Olsen David B. |
Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds
|
US20040229839A1
(en)
|
2003-05-14 |
2004-11-18 |
Biocryst Pharmaceuticals, Inc. |
Substituted nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases
|
WO2004106356A1
(en)
|
2003-05-27 |
2004-12-09 |
Syddansk Universitet |
Functionalized nucleotide derivatives
|
CA2734052A1
(en)
*
|
2003-05-30 |
2005-01-13 |
Pharmasset, Inc. |
Modified fluorinated nucleoside analogues
|
CN1809582A
(zh)
|
2003-06-19 |
2006-07-26 |
弗·哈夫曼-拉罗切有限公司 |
制备4'-叠氮基核苷衍生物的方法
|
AU2004258750A1
(en)
|
2003-07-25 |
2005-02-03 |
Centre National De La Recherche Scientifique -Cnrs |
Purine nucleoside analogues for treating diseases caused by flaviviridae including hepatitis C
|
DE10335061B4
(de)
|
2003-07-31 |
2005-11-17 |
Wacker-Chemie Gmbh |
Verfahren zur Herstellung von OH-geschützten [4-(2,6-damino-9H-purin-9-yl)-1,3-dioxolan-2-yl]methanol-Derivaten
|
WO2005090370A1
(en)
|
2004-02-05 |
2005-09-29 |
The Regents Of The University Of California |
Pharmacologically active agents containing esterified phosphonates and methods for use thereof
|
CA2568379A1
(en)
|
2004-06-15 |
2005-12-29 |
Merck & Co., Inc. |
C-purine nucleoside analogs as inhibitors of rna-dependent rna viral polymerase
|
US7560434B2
(en)
|
2004-06-22 |
2009-07-14 |
Biocryst Pharmaceuticals, Inc. |
AZA nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases
|
US20070265222A1
(en)
|
2004-06-24 |
2007-11-15 |
Maccoss Malcolm |
Nucleoside Aryl Phosphoramidates for the Treatment of Rna-Dependent Rna Viral Infection
|
EP1761229B1
(en)
|
2004-06-29 |
2011-10-05 |
Avery Dennison Corporation |
Nonwoven-elastomeric laminate with improved bonding between elastomer and nonwoven web
|
CN101023094B
(zh)
|
2004-07-21 |
2011-05-18 |
法莫赛特股份有限公司 |
烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
PL3109244T3
(pl)
|
2004-09-14 |
2019-09-30 |
Gilead Pharmasset Llc |
Wytwarzanie 2'fluoro-2'-alkilo-podstawionych lub innych ewentualnie podstawionych rybofuranozylopirymidyn i puryn oraz ich pochodnych
|
AU2005302448B2
(en)
|
2004-10-29 |
2012-07-19 |
Biocryst Pharmaceuticals, Inc. |
Therapeutic furopyrimidines and thienopyrimidines
|
US8399428B2
(en)
|
2004-12-09 |
2013-03-19 |
Regents Of The University Of Minnesota |
Nucleosides with antiviral and anticancer activity
|
CN101115725A
(zh)
|
2004-12-10 |
2008-01-30 |
埃莫里大学 |
治疗病毒感染和异常细胞增殖的2’和3’-取代的环丁基核苷类似物
|
JP2008532950A
(ja)
|
2005-03-08 |
2008-08-21 |
バイオタ サイエンティフィック マネージメント ピーティーワイ リミテッド |
治療薬としての二環式ヌクレオシドおよび二環式ヌクレオチド
|
WO2006102533A2
(en)
|
2005-03-23 |
2006-09-28 |
Neopharm, Inc. |
Pharmaceutically active lipid-based formulation of nucleoside-lipid conjugates
|
EP2537520A1
(en)
|
2005-03-29 |
2012-12-26 |
Biocryst Pharmaceuticals, Inc. |
Hepatics C therapies
|
WO2006130217A2
(en)
|
2005-04-01 |
2006-12-07 |
The Regents Of The University Of California |
Substituted phosphate esters of nucleoside phosphonates
|
WO2006121820A1
(en)
|
2005-05-05 |
2006-11-16 |
Valeant Research & Development |
Phosphoramidate prodrugs for treatment of viral infection
|
AU2006280175B2
(en)
|
2005-08-09 |
2011-09-01 |
Merck Sharp & Dohme Corp. |
Ribonucleoside cyclic acetal derivatives for the treatment of RNA-dependent RNA viral infection
|
WO2007020193A2
(en)
|
2005-08-15 |
2007-02-22 |
F. Hoffmann-La Roche Ag |
Antiviral phosphoramidates of 4 ' -substituted pronucleotides
|
WO2007095269A2
(en)
|
2006-02-14 |
2007-08-23 |
Merck & Co., Inc. |
Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
|
US8895531B2
(en)
|
2006-03-23 |
2014-11-25 |
Rfs Pharma Llc |
2′-fluoronucleoside phosphonates as antiviral agents
|
EP2012799B1
(en)
|
2006-05-03 |
2016-08-24 |
Chimerix, Inc. |
Metabolically stable alkoxyalkyl esters of antiviral or antiproliferative phosphonates, nucleoside phosphonates and nucleoside phosphates
|
US7842672B2
(en)
|
2006-07-07 |
2010-11-30 |
Gilead Sciences, Inc. |
Phosphonate inhibitors of HCV
|
RU2421461C2
(ru)
|
2006-10-10 |
2011-06-20 |
Фармассет, Инк. |
Способ получения рибофуранозил-пиримидиновых нуклеозидов
|
PL216525B1
(pl)
|
2006-10-17 |
2014-04-30 |
Ct Badań Molekularnych I Makromolekularnych Polskiej Akademii Nauk |
5'-O-[(N-acylo)amidoditiofosforano] nukleozydy oraz sposób wytwarzania 5'-O-[(N-acylo)amidofosforano]-,5'-O-[(N-acylo)amidotiofosforano]-, 5'-O-[(N-acylo)amidoditiofosforano]nukleozydów
|
GB0623493D0
(en)
|
2006-11-24 |
2007-01-03 |
Univ Cardiff |
Chemical compounds
|
CA2672613A1
(en)
|
2006-12-20 |
2008-07-03 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Nucleoside cyclic phosphoramidates for the treatment of rna-dependent rna viral infection
|
US20080261913A1
(en)
|
2006-12-28 |
2008-10-23 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of liver disorders
|
EP2124555B1
(en)
|
2007-01-05 |
2015-07-08 |
Merck Sharp & Dohme Corp. |
Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
|
EP2535345A1
(en)
|
2007-01-12 |
2012-12-19 |
BioCryst Pharmaceuticals, Inc. |
Anticancer nucleoside analogs
|
JP2010518015A
(ja)
|
2007-01-31 |
2010-05-27 |
アリオス バイオファーマ インク. |
2−5aアナログ類およびそれらの使用方法
|
WO2008100447A2
(en)
|
2007-02-09 |
2008-08-21 |
Gilead Sciences, Inc. |
Nucleoside analogs for antiviral treatment
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
PL2155758T3
(pl)
|
2007-05-10 |
2013-06-28 |
Biocryst Pharm Inc |
Pochodne tetrahydrofuro[3,4-d]dioksolanu przeznaczone do stosowania w leczeniu infekcji wirusowych i raka
|
BRPI0811633A2
(pt)
|
2007-05-14 |
2017-06-06 |
Univ Emory |
compostos de fórmulas (i) e (ii), método de tratamento de hospedeiro infectado por hiv-1, hiv-2, hbv ou hcv, método de prevenção de infecção por hiv-1, hiv-2, hbv ou hcv, método para reduzir atividade biológica de infecção por hiv-1, hiv-2, hbv ou hcv e composição farmacêutica
|
ES2530763T3
(es)
|
2007-06-25 |
2015-03-05 |
Anadys Pharmaceuticals Inc |
Procedimiento continuo de hidrólisis enzimática
|
US20090060867A1
(en)
|
2007-08-31 |
2009-03-05 |
Idenix Pharmaceuticals, Inc. |
Phosphadiazine hcv polymerase inhibitors iii and vi
|
US20090318380A1
(en)
|
2007-11-20 |
2009-12-24 |
Pharmasset, Inc. |
2',4'-substituted nucleosides as antiviral agents
|
WO2009086192A1
(en)
|
2007-12-21 |
2009-07-09 |
Alios Biopharma, Inc. |
Biodegradable phosphate protected nucleotide derivatives and their use as cancer, anti viral and anti parasitic agents
|
WO2009086201A1
(en)
|
2007-12-21 |
2009-07-09 |
Alios Biopharma, Inc. |
2-5a analogs and their use as anti-cancer, anti-viral and anti- paras iti c agents
|
TW200942243A
(en)
|
2008-03-05 |
2009-10-16 |
Biocryst Pharm Inc |
Antiviral therapeutic agents
|
WO2009129120A2
(en)
|
2008-04-15 |
2009-10-22 |
Rfs Pharma, Llc |
Nucleoside derivatives for treatment of caliciviridae infections, including norovirus infections
|
AR071395A1
(es)
|
2008-04-23 |
2010-06-16 |
Gilead Sciences Inc |
Analogos carba-nucleosidos 1'-sustituidos para tratamiento antiviral
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
AR072428A1
(es)
|
2008-07-01 |
2010-08-25 |
Medivir Ab |
Derivados de pirimidin nucleotidos inhibidores de polimerasas del virus de la hepatitis c (vhc), composiciones farmaceuticas que los contienen y metodo para prepararlos.
|
WO2010002877A2
(en)
|
2008-07-03 |
2010-01-07 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
CA2734486A1
(en)
|
2008-08-20 |
2010-02-25 |
Southern Research Institute |
Substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
WO2010022125A1
(en)
|
2008-08-20 |
2010-02-25 |
Schering Corporation |
Ethynyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
ES2439009T3
(es)
|
2008-08-20 |
2014-01-21 |
Merck Sharp & Dohme Corp. |
Derivados de piridina y pirimidina sustituidos con etenilo y su uso en el tratamiento de infecciones virales
|
TW201019939A
(en)
|
2008-08-20 |
2010-06-01 |
Schering Corp |
Azo-substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
PA8852101A1
(es)
|
2008-12-08 |
2010-07-27 |
Medivir Ab |
Nucleótidos uracil ciclopropílicos
|
WO2010068708A2
(en)
|
2008-12-09 |
2010-06-17 |
Rfs Pharma, Llc |
3'-azido purine nucleotide prodrugs for treatment of viral infections
|
PT2376088T
(pt)
|
2008-12-23 |
2017-05-02 |
Gilead Pharmasset Llc |
Fosforamidatos de nucleósidos de 2-amino-purina 6-osubstituída
|
CN102753563A
(zh)
*
|
2008-12-23 |
2012-10-24 |
吉利德制药有限责任公司 |
核苷类似物
|
AR074977A1
(es)
|
2008-12-23 |
2011-03-02 |
Pharmasset Inc |
Sintesis de nucleosidos de purina
|
BRPI1004575A2
(pt)
|
2009-01-09 |
2016-04-05 |
Inhibitex Inc |
composto, composição farmacêutica, método de tratamento de infecções virais, método de separação dos diaestereômeros de fósforo
|
KR101774429B1
(ko)
|
2009-02-06 |
2017-09-04 |
코크리스탈 파마, 아이엔씨. |
암 및 바이러스 감염 치료용 퓨린 뉴클레오시드 모노포스페이트 프로드럭
|
EP2719701B1
(en)
|
2009-02-10 |
2017-04-05 |
Gilead Sciences, Inc. |
Method for the preparation of thieno[3,4-d]pyrimidin-7-yl ribosides
|
AR075584A1
(es)
|
2009-02-27 |
2011-04-20 |
Intermune Inc |
COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO.
|
WO2010101967A2
(en)
|
2009-03-04 |
2010-09-10 |
Idenix Pharmaceuticals, Inc. |
Phosphothiophene and phosphothiazole hcv polymerase inhibitors
|
WO2010108135A1
(en)
|
2009-03-20 |
2010-09-23 |
Alios Biopharma, Inc. |
Protected nucleotide analogs
|
AU2010226466A1
(en)
|
2009-03-20 |
2011-10-20 |
Alios Biopharma, Inc. |
Substituted nucleoside and nucleotide analogs
|
JO3027B1
(ar)
|
2009-05-14 |
2016-09-05 |
Janssen Products Lp |
نيوكليوسيدات يوراسيل سبيرواوكسيتان
|
TWI576352B
(zh)
|
2009-05-20 |
2017-04-01 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
WO2011005595A2
(en)
|
2009-06-24 |
2011-01-13 |
Alios Biopharma, Inc. |
2-5a analogs and their methods of use
|
US8927513B2
(en)
|
2009-07-07 |
2015-01-06 |
Alnylam Pharmaceuticals, Inc. |
5′ phosphate mimics
|
US7973013B2
(en)
|
2009-09-21 |
2011-07-05 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
WO2011039221A2
(en)
|
2009-09-29 |
2011-04-07 |
Centocor Ortho Biotech Products L.P. |
Phosphoramidate derivatives of nucleosides
|
US8816074B2
(en)
|
2009-11-16 |
2014-08-26 |
University of Georgia Foundation, Inc. |
2′-fluoro-6′-methylene carbocyclic nucleosides and methods of treating viral infections
|
AP2012006310A0
(en)
|
2009-11-16 |
2012-06-30 |
Univ Georgia |
2'fluoro-6'-methylene carbocyclic nucleosides and methods of treating viral infections.
|
EP2513113B1
(en)
|
2009-12-18 |
2018-08-01 |
Idenix Pharmaceuticals LLC |
5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
|
CN102858790A
(zh)
|
2010-03-31 |
2013-01-02 |
吉利德制药有限责任公司 |
核苷氨基磷酸酯
|
US8563530B2
(en)
*
|
2010-03-31 |
2013-10-22 |
Gilead Pharmassel LLC |
Purine nucleoside phosphoramidate
|
CA2795054A1
(en)
|
2010-04-01 |
2011-10-06 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
TW201201815A
(en)
|
2010-05-28 |
2012-01-16 |
Gilead Sciences Inc |
1'-substituted-carba-nucleoside prodrugs for antiviral treatment
|
JP5937073B2
(ja)
|
2010-07-19 |
2016-06-22 |
ギリード・サイエンシズ・インコーポレーテッド |
ジアステレオマーとして純粋なホスホルアミデートプロドラッグの調製方法
|
US8859595B2
(en)
|
2010-08-26 |
2014-10-14 |
Rfs Pharma, Llc |
Potent and selective inhibitors of hepatitis C virus
|
AU2011305652B2
(en)
|
2010-09-22 |
2016-10-20 |
Janssen Biopharma, Inc. |
Azido nucleosides and nucleotide analogs
|
WO2012040126A1
(en)
|
2010-09-22 |
2012-03-29 |
Alios Biopharma, Inc. |
Substituted nucleotide analogs
|
KR20130110170A
(ko)
|
2010-09-22 |
2013-10-08 |
앨리오스 바이오파마 인크. |
치환된 뉴클레오타이드 유사체
|
WO2012041965A1
(en)
|
2010-09-29 |
2012-04-05 |
Universidad Nacional De Quilmes |
Process for producing dialkylphosphotriesters of nucleosides by enzymatic transesterification and deprotection thereof for producing nucleoside monophosphates
|
WO2012048013A2
(en)
|
2010-10-06 |
2012-04-12 |
Inhibitex, Inc. |
Phosphorodiamidate derivatives of guanosine nucleoside compounds for treatment of viral injections
|
PL2638054T3
(pl)
|
2010-11-10 |
2015-05-29 |
Janssen Products Lp |
Fosforoamidany nukleozydów uracylo-spirooksetanowych
|
TW201242974A
(en)
|
2010-11-30 |
2012-11-01 |
Gilead Pharmasset Llc |
Compounds
|
NZ613370A
(en)
*
|
2010-12-20 |
2015-05-29 |
Gilead Sciences Inc |
Combinations for treating hcv
|
EP2655392B1
(en)
|
2010-12-22 |
2018-04-18 |
Alios Biopharma, Inc. |
Cyclic nucleotide analogs
|
EP2658857B1
(en)
|
2010-12-29 |
2016-11-02 |
Inhibitex, Inc. |
Substituted purine nucleosides, phosphoroamidate and phosphorodiamidate derivatives for treatment of viral infections
|
WO2012094248A1
(en)
|
2011-01-03 |
2012-07-12 |
Nanjing Molecular Research, Inc. |
O-(substituted benzyl) phosphoramidate compounds and therapeutic use
|
WO2012125900A1
(en)
|
2011-03-16 |
2012-09-20 |
Enanta Pharmaceuticals, Inc. |
2'-allene-substituted nucleoside derivatives
|
EP2691409B1
(en)
|
2011-03-31 |
2018-02-21 |
Idenix Pharmaceuticals LLC. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
US9156872B2
(en)
|
2011-04-13 |
2015-10-13 |
Merck Sharp & Dohme Corp. |
2′-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
CA2830689A1
(en)
|
2011-04-13 |
2012-10-18 |
Gilead Sciences, Inc. |
1'-substituted pyrimidine n-nucleoside analogs for antiviral treatment
|
BR112013026345A2
(pt)
|
2011-04-13 |
2019-04-24 |
Merck Sharp & Dohe Corp. |
composto, composição farmacêutica, uso de um composto, e, método para tratar um paciente infectado com hcv
|
WO2012158811A2
(en)
|
2011-05-19 |
2012-11-22 |
Rfs Pharma, Llc |
Purine monophosphate prodrugs for treatment of viral infections
|
WO2013009737A1
(en)
|
2011-07-13 |
2013-01-17 |
Merck Sharp & Dohme Corp. |
5'-substituted nucleoside analogs and methods of use thereof for the treatment of viral diseases
|
WO2013039855A1
(en)
|
2011-09-12 |
2013-03-21 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
TW201329096A
(zh)
|
2011-09-12 |
2013-07-16 |
Idenix Pharmaceuticals Inc |
經取代羰氧基甲基磷酸醯胺化合物及用於治療病毒感染之藥學組成物
|
WO2013044030A1
(en)
|
2011-09-23 |
2013-03-28 |
Enanta Pharmaceuticals, Inc. |
2'-chloroacetylenyl substituted nucleoside derivatives
|
TW201331221A
(zh)
|
2011-10-14 |
2013-08-01 |
Idenix Pharmaceuticals Inc |
嘌呤核苷酸化合物類之經取代的3’,5’-環磷酸酯及用於治療病毒感染之醫藥組成物
|
AU2012325801B2
(en)
*
|
2011-10-19 |
2016-05-12 |
Mercator Medsystems, Inc. |
Localized modulation of tissues and cells to enhance therapeutic effects including renal denervation
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
US20130244966A1
(en)
|
2011-12-12 |
2013-09-19 |
Catabasis Pharmaceuticals, Inc. |
Fatty acid antiviral conjugates and their uses
|
US8980865B2
(en)
|
2011-12-22 |
2015-03-17 |
Alios Biopharma, Inc. |
Substituted nucleotide analogs
|
US8673926B2
(en)
|
2012-02-14 |
2014-03-18 |
University Of Georgia Research Foundation, Inc. |
Spiro[2.4]heptanes for treatment of flaviviridae infections
|
MX352171B
(es)
*
|
2012-02-27 |
2017-11-13 |
Bristol Myers Squibb Co |
Sal de hemisulfato de n-(5s,6s,9r)-5-amino-6-(2,3-difluorofenil)-6 ,7,8,9-tetrahidro-5h-ciclohepta[b]piridin-9-il-4-(2-oxo-2,3-dihid ro-1h-imidazo[4,5-b]piridin-1-il)piperidina-1-carboxilato.
|
WO2013142159A1
(en)
|
2012-03-21 |
2013-09-26 |
Alios Biopharma, Inc. |
Pharmaceutical combinations comprising a thionucleotide analog
|
US8846896B2
(en)
|
2012-03-21 |
2014-09-30 |
Alios Biopharma, Inc. |
Methods of preparing substituted nucleotide analogs
|
EP2827876A4
(en)
|
2012-03-22 |
2015-10-28 |
Alios Biopharma Inc |
PHARMACEUTICAL COMBINATIONS WITH A THIONUCLEOTIDE ANALOG
|
US20150057243A1
(en)
|
2012-04-02 |
2015-02-26 |
Northern University |
Compositions and Methods for the Inhibition of Methyltransferases
|
US8846638B2
(en)
|
2012-05-17 |
2014-09-30 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic nucleoside phosphoramidate derivatives
|
WO2013177188A1
(en)
|
2012-05-22 |
2013-11-28 |
Idenix Pharmaceuticals, Inc. |
3',5'-cyclic phosphoramidate prodrugs for hcv infection
|
CA2873315A1
(en)
|
2012-05-22 |
2013-11-28 |
Idenix Pharamaceuticals, Inc. |
D-amino acid compounds for liver disease
|
WO2013187978A1
(en)
|
2012-06-16 |
2013-12-19 |
Nanjing Molecular Research, Inc. |
Double-liver-targeting phosphoramidate and phosphonoamidate prodrugs
|
EP2870169A1
(en)
|
2012-07-03 |
2015-05-13 |
Bristol-Myers Squibb Company |
Process for preparing diastereomerically enriched phosphoramidate derivatives of nucleoside compounds for treatment of viral infections
|
WO2014047117A1
(en)
|
2012-09-18 |
2014-03-27 |
Bristol-Myers Squibb Company |
Process for preparing phosphoramidate derivatives of nucleoside compounds for treatment of viral infections
|
WO2014052638A1
(en)
|
2012-09-27 |
2014-04-03 |
Idenix Pharmaceuticals, Inc. |
Esters and malonates of sate prodrugs
|
EP2909223B1
(en)
|
2012-10-19 |
2017-03-22 |
Idenix Pharmaceuticals LLC |
Dinucleotide compounds for hcv infection
|
CN104884462A
(zh)
|
2012-10-29 |
2015-09-02 |
共晶制药股份有限公司 |
用于治疗病毒感染和癌症的嘧啶核苷及其单磷酸酯前药
|
SG11201503750YA
(en)
|
2012-11-16 |
2015-06-29 |
Univ Cardiff |
Process for preparing nucleoside prodrugs
|
US20140205566A1
(en)
|
2012-11-30 |
2014-07-24 |
Novartis Ag |
Cyclic nucleuoside derivatives and uses thereof
|
US9211300B2
(en)
|
2012-12-19 |
2015-12-15 |
Idenix Pharmaceuticals Llc |
4′-fluoro nucleosides for the treatment of HCV
|
WO2014100498A1
(en)
|
2012-12-21 |
2014-06-26 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
GEP201706757B
(en)
|
2012-12-21 |
2017-10-25 |
Alios Biopharma Inc |
Substituted nucleosides, nucleotides and analogs thereof
|
BR112014011938B1
(pt)
|
2013-01-31 |
2021-03-16 |
Gilead Pharmasset Llc |
composição farmacêutica na forma de um comprimido com uma combinação de dose fixa de dois compostos antivirais, forma de dosagem farmacêutica compreendendo a referida composição e uso da referida composição
|
WO2014124430A1
(en)
|
2013-02-11 |
2014-08-14 |
Emory University |
Nucleotide and nucleoside therapeutic compositions and uses related thereto
|
US9339541B2
(en)
|
2013-03-04 |
2016-05-17 |
Merck Sharp & Dohme Corp. |
Thiophosphate nucleosides for the treatment of HCV
|
EP2981542B1
(en)
|
2013-04-01 |
2021-09-15 |
Idenix Pharmaceuticals LLC |
2',4'-fluoro nucleosides for the treatment of hcv
|
JP2016522172A
(ja)
|
2013-04-12 |
2016-07-28 |
アキリオン ファーマシューティカルズ,インコーポレーテッド |
Hcvを治療するのに有用な重水素化されたヌクレオシドプロドラッグ
|
CN103435672A
(zh)
|
2013-04-25 |
2013-12-11 |
刘沛 |
含有取代苄基的新型核苷磷酸酯前药的结构与合成
|
TW201542578A
(zh)
|
2013-06-26 |
2015-11-16 |
Alios Biopharma Inc |
經取代之核苷、核苷酸及其類似物
|
US20150011481A1
(en)
|
2013-07-02 |
2015-01-08 |
Abbvie Inc. |
Methods for Treating HCV
|
SI3043803T1
(sl)
|
2013-09-11 |
2022-09-30 |
Emory University |
Nukleotidne in nukleozidne sestave in njihova uporaba
|
US8889701B1
(en)
|
2013-10-11 |
2014-11-18 |
Alla Chem, Llc |
Substituted (S)-(2R,3R,5R)-3-hydroxy-(5-pyrimidin-1-yl)tetrahydrofuran-2-ylmethyl aryl phosphoramidate
|
EP3055319A4
(en)
|
2013-10-11 |
2018-01-10 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
US20160271162A1
(en)
*
|
2013-11-01 |
2016-09-22 |
Idenix Pharmacueticals, Llc |
D-alanine phosphoramide pronucleotides of 2'-methyl 2'-fluro guanosine nucleoside compounds for the treatment of hcv
|
KR20160099090A
(ko)
|
2013-11-27 |
2016-08-19 |
아이데닉스 파마슈티칼스 엘엘씨 |
간암의 치료를 위한 뉴클레오티드
|
WO2015084741A2
(en)
|
2013-12-02 |
2015-06-11 |
Gilead Pharmasset Llc |
Methods of treating hepatitis c virus infection in subjects with cirrhosis
|
WO2015095305A1
(en)
|
2013-12-17 |
2015-06-25 |
Idenix Pharmaceuticals, Inc. |
Production of cyclic phosphate, phosphoramidate, thiophosphate, and phosphonate nucleoside compounds
|
US20170022242A1
(en)
|
2014-04-17 |
2017-01-26 |
Katholieke Universiteit Leuven, KU LEUVEN R&D |
Novel antiviral and antitumoral compounds
|
MA40031A
(fr)
|
2014-06-24 |
2015-12-30 |
Alios Biopharma Inc |
Nucléosides substitués, nucléotides et analogues de ceux-ci
|
JP6728075B2
(ja)
|
2014-06-24 |
2020-07-22 |
ヤンセン バイオファーマ インク. |
置換ヌクレオシド、ヌクレオチドおよびその類似体
|
WO2016041877A1
(en)
|
2014-09-15 |
2016-03-24 |
Medivir Ab |
Methods for the preparation of diastereomerically pure phosphoramidate prodrugs
|
MA41441A
(fr)
|
2014-12-19 |
2017-12-12 |
Alios Biopharma Inc |
Nucléosides substitués, nucléotides et analogues de ceux-ci
|
MA41213A
(fr)
|
2014-12-19 |
2017-10-24 |
Alios Biopharma Inc |
Nucléosides substitués, nucléotides et analogues de ceux-ci
|
SG11201706841PA
(en)
|
2015-03-06 |
2017-09-28 |
Atea Pharmaceuticals Inc |
ß-D-2'-DEOXY-2'a-FLUORO-2'-ß-C-SUBSTITUTED-2-MODIFIED-N<sp>6</sp>-SUBSTITUTED PURINE NUCLEOTIDES FOR HCV TREATMENT
|
WO2016145142A1
(en)
|
2015-03-10 |
2016-09-15 |
Emory University |
Nucleotide and nucleoside therapeutics compositions and uses related thereto
|
CN106188192B
(zh)
|
2015-04-29 |
2019-09-10 |
刘沛 |
含d-氨基酸酯的核苷氨基磷酸/膦酸酯衍生物及其医药用途
|
US10202412B2
(en)
|
2016-07-08 |
2019-02-12 |
Atea Pharmaceuticals, Inc. |
β-D-2′-deoxy-2′-substituted-4′-substituted-2-substituted-N6-substituted-6-aminopurinenucleotides for the treatment of paramyxovirus and orthomyxovirus infections
|
WO2018009623A1
(en)
|
2016-07-08 |
2018-01-11 |
Atea Pharmaceuticals, Inc. |
β-D-2'-DEOXY-2'-SUBSTITUTED-4'-SUBSTITUTED-2-SUBSTITUTED-N6-SUBSTITUTED-6-AMINOPURINE NUCLEOTIDES FOR THE TREATMENT OF PARAMYXOVIRUS AND ORTHOMYXOVIRUS INFECTIONS
|
US10711029B2
(en)
|
2016-07-14 |
2020-07-14 |
Atea Pharmaceuticals, Inc. |
Beta-d-2′-deoxy-2′-alpha-fluoro-2′-beta-c-substituted-4′fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
|
MY197236A
(en)
|
2016-09-07 |
2023-06-07 |
Atea Pharmaceuticals Inc |
2'-substituted-n6-substituted purine nucleotides for rna virus treatment
|
KR102592899B1
(ko)
*
|
2017-02-01 |
2023-10-24 |
아테아 파마슈티컬즈, 인크. |
C형 간염 바이러스를 치료하기 위한 뉴클레오티드 헤미-술페이트 염
|
CN112351799A
(zh)
|
2018-04-10 |
2021-02-09 |
阿堤亚制药公司 |
具有硬化的hcv感染患者的治疗
|