SG10201913685YA - Fibronectin based scaffold domain proteins that bind to myostatin - Google Patents
Fibronectin based scaffold domain proteins that bind to myostatinInfo
- Publication number
- SG10201913685YA SG10201913685YA SG10201913685YA SG10201913685YA SG10201913685YA SG 10201913685Y A SG10201913685Y A SG 10201913685YA SG 10201913685Y A SG10201913685Y A SG 10201913685YA SG 10201913685Y A SG10201913685Y A SG 10201913685YA SG 10201913685Y A SG10201913685Y A SG 10201913685YA
- Authority
- SG
- Singapore
- Prior art keywords
- myostatin
- bind
- domain proteins
- based scaffold
- scaffold domain
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261700697P | 2012-09-13 | 2012-09-13 | |
US201361780005P | 2013-03-13 | 2013-03-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201913685YA true SG10201913685YA (en) | 2020-03-30 |
Family
ID=49253416
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201701970TA SG10201701970TA (en) | 2012-09-13 | 2013-09-12 | Fibronectin based scaffold domain proteins that bind to myostatin |
SG11201501741YA SG11201501741YA (en) | 2012-09-13 | 2013-09-12 | Fibronectin based scaffold domain proteins that bind to myostatin |
SG10201913685YA SG10201913685YA (en) | 2012-09-13 | 2013-09-12 | Fibronectin based scaffold domain proteins that bind to myostatin |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201701970TA SG10201701970TA (en) | 2012-09-13 | 2013-09-12 | Fibronectin based scaffold domain proteins that bind to myostatin |
SG11201501741YA SG11201501741YA (en) | 2012-09-13 | 2013-09-12 | Fibronectin based scaffold domain proteins that bind to myostatin |
Country Status (32)
Country | Link |
---|---|
US (8) | US8933199B2 (fr) |
EP (3) | EP2895503B1 (fr) |
JP (2) | JP6346895B2 (fr) |
KR (3) | KR102424590B1 (fr) |
CN (2) | CN104768969B (fr) |
AU (2) | AU2013315482B2 (fr) |
BR (1) | BR112015005466B1 (fr) |
CA (1) | CA2884730C (fr) |
CL (1) | CL2015000500A1 (fr) |
DK (2) | DK3564258T3 (fr) |
EA (1) | EA033536B1 (fr) |
ES (2) | ES2727453T3 (fr) |
HK (1) | HK1212717A1 (fr) |
HR (2) | HRP20190845T1 (fr) |
HU (2) | HUE043482T2 (fr) |
IL (3) | IL270110B (fr) |
LT (3) | LT3835310T (fr) |
MX (2) | MX366666B (fr) |
MY (2) | MY172863A (fr) |
NZ (1) | NZ628446A (fr) |
PE (1) | PE20150954A1 (fr) |
PH (1) | PH12015500397A1 (fr) |
PL (2) | PL2895503T3 (fr) |
PT (2) | PT2895503T (fr) |
RS (2) | RS58801B1 (fr) |
SG (3) | SG10201701970TA (fr) |
SI (2) | SI3564258T1 (fr) |
TN (1) | TN2015000086A1 (fr) |
TW (2) | TWI694085B (fr) |
UY (1) | UY35027A (fr) |
WO (1) | WO2014043344A1 (fr) |
ZA (1) | ZA201501457B (fr) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2568436T3 (es) | 2006-03-31 | 2016-04-29 | Chugai Seiyaku Kabushiki Kaisha | Procedimiento para controlar la farmacocinética en sangre de anticuerpos |
EP3689912A1 (fr) | 2007-09-26 | 2020-08-05 | Chugai Seiyaku Kabushiki Kaisha | Procédé de modification d'un anticorps par point isoélectrique par substitution d'acide aminé dans cdr |
EP4238993A3 (fr) | 2008-04-11 | 2023-11-29 | Chugai Seiyaku Kabushiki Kaisha | Molécule de liaison à l'antigène capable de se lier à deux ou plusieurs molécules d'antigène de manière répétée |
US9562089B2 (en) * | 2010-05-26 | 2017-02-07 | Bristol-Myers Squibb Company | Fibronectin based scaffold proteins having improved stability |
SG190727A1 (en) | 2010-11-30 | 2013-07-31 | Chugai Pharmaceutical Co Ltd | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
PT2697257T (pt) * | 2011-04-13 | 2016-12-28 | Bristol Myers Squibb Co | Proteínas de fusão fc compreendendo novos ligantes ou arranjos |
JP6774164B2 (ja) | 2012-08-24 | 2020-10-21 | 中外製薬株式会社 | マウスFcγRII特異的Fc抗体 |
TWI697501B (zh) | 2012-08-24 | 2020-07-01 | 日商中外製藥股份有限公司 | FcγRIIb特異性Fc區域變異體 |
CN104768969B (zh) | 2012-09-13 | 2021-04-16 | 百时美施贵宝公司 | 结合至肌生成抑制素的基于纤连蛋白的支架结构域蛋白 |
ES2715710T3 (es) | 2013-01-25 | 2019-06-05 | Shire Human Genetic Therapies | Folistatina en el tratamiento de la distrofía muscular de Duchenne |
US20150361159A1 (en) | 2013-02-01 | 2015-12-17 | Bristol-Myers Squibb Company | Fibronectin based scaffold proteins |
EP3406629B1 (fr) | 2013-02-06 | 2020-06-24 | Bristol-Myers Squibb Company | Protéines du domaine de la fibronectine de type iii à solubilité améliorée |
US10065987B2 (en) | 2013-02-12 | 2018-09-04 | Bristol-Myers Squibb Company | High pH protein refolding methods |
WO2014163101A1 (fr) | 2013-04-02 | 2014-10-09 | 中外製薬株式会社 | Variant de région fc |
EP3816625A1 (fr) | 2013-05-06 | 2021-05-05 | Scholar Rock, Inc. | Compositions et procédés de modulation de facteur de croissance |
MX2016011580A (es) | 2014-03-20 | 2016-11-29 | Bristol Myers Squibb Co | Dominios de fibronectina tipo iii que se unen a albumina de suero. |
EP3647322B1 (fr) | 2014-03-20 | 2021-10-20 | Bristol-Myers Squibb Company | Molécules de charpente à base de fibronectine stabilisée |
US10016394B2 (en) | 2014-04-16 | 2018-07-10 | The Scripps Research Institute | PPARG modulators for treatment of osteoporosis |
US11072681B2 (en) | 2014-07-28 | 2021-07-27 | The Regents Of The University Of California | Compositions and methods of making polymerizing nucleic acids |
WO2016023036A1 (fr) * | 2014-08-08 | 2016-02-11 | The Regents Of The University Of California | Polymères peptidiques à haute densité |
US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
EP3789399A1 (fr) | 2014-11-21 | 2021-03-10 | Bristol-Myers Squibb Company | Anticorps comprenant des régions constantes de chaîne lourde modifiées |
KR102569813B1 (ko) | 2014-11-21 | 2023-08-24 | 브리스톨-마이어스 스큅 컴퍼니 | Cd73에 대항한 항체 및 그의 용도 |
CN107207379B (zh) | 2014-11-25 | 2021-08-10 | 百时美施贵宝公司 | 用于生物制品的18f-放射性标记的方法和组合物 |
ES2822990T3 (es) | 2014-11-25 | 2021-05-05 | Bristol Myers Squibb Co | Novedosos polipéptidos de unión a PD-L1 para obtención de imágenes |
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TW201842929A (zh) | 2017-05-03 | 2018-12-16 | 美商必治妥美雅史谷比公司 | 結合至肌肉生長抑制素以纖維連接蛋白為主之支架結構域蛋白質的穩定調配物 |
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