SE9501384D0 - Process for the preparation of respirable particles - Google Patents

Process for the preparation of respirable particles

Info

Publication number
SE9501384D0
SE9501384D0 SE9501384A SE9501384A SE9501384D0 SE 9501384 D0 SE9501384 D0 SE 9501384D0 SE 9501384 A SE9501384 A SE 9501384A SE 9501384 A SE9501384 A SE 9501384A SE 9501384 D0 SE9501384 D0 SE 9501384D0
Authority
SE
Sweden
Prior art keywords
preparation
solvent
inhalation
respirable particles
compound
Prior art date
Application number
SE9501384A
Other languages
English (en)
Swedish (sv)
Inventor
Edib Jakupovic
Jan Trofast
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20397958&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE9501384(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9501384A priority Critical patent/SE9501384D0/xx
Publication of SE9501384D0 publication Critical patent/SE9501384D0/xx
Priority to SA96160645A priority patent/SA96160645B1/ar
Priority to ZA962596A priority patent/ZA962596B/xx
Priority to TW085103802A priority patent/TW492877B/zh
Priority to IN723DE1996 priority patent/IN185119B/en
Priority to IL11784196A priority patent/IL117841A/en
Priority to CN96194372A priority patent/CN1102383C/zh
Priority to PT96910285T priority patent/PT820276E/pt
Priority to EP96910285A priority patent/EP0820276B1/en
Priority to CA002217062A priority patent/CA2217062A1/en
Priority to PCT/SE1996/000479 priority patent/WO1996032095A1/en
Priority to AR33616796A priority patent/AR001624A1/es
Priority to NZ305515A priority patent/NZ305515A/xx
Priority to DK96910285T priority patent/DK0820276T3/da
Priority to US08/669,477 priority patent/US6221398B1/en
Priority to AU53524/96A priority patent/AU694863B2/en
Priority to ES96910285T priority patent/ES2188750T3/es
Priority to JP8530963A priority patent/JPH11503448A/ja
Priority to DE69625589T priority patent/DE69625589T2/de
Priority to AT96910285T priority patent/ATE230257T1/de
Priority to MYPI96001419A priority patent/MY117344A/en
Priority to NO19974557A priority patent/NO316209B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
SE9501384A 1995-04-13 1995-04-13 Process for the preparation of respirable particles SE9501384D0 (sv)

Priority Applications (22)

Application Number Priority Date Filing Date Title
SE9501384A SE9501384D0 (sv) 1995-04-13 1995-04-13 Process for the preparation of respirable particles
SA96160645A SA96160645B1 (ar) 1995-04-13 1996-03-04 عملية لتحضير جسيمات صالحه للتنفس
ZA962596A ZA962596B (en) 1995-04-13 1996-04-01 Process for the preparation of respirable particles
TW085103802A TW492877B (en) 1995-04-13 1996-04-01 Process for the preparation of respirable particles
IN723DE1996 IN185119B (enExample) 1995-04-13 1996-04-02
IL11784196A IL117841A (en) 1995-04-13 1996-04-08 Process for the preparation of pharmaceutical powder for inhalation
DE69625589T DE69625589T2 (de) 1995-04-13 1996-04-12 Verfahren zur herstellung einatembarer partikel
AT96910285T ATE230257T1 (de) 1995-04-13 1996-04-12 Verfahren zur herstellung einatembarer partikel
CA002217062A CA2217062A1 (en) 1995-04-13 1996-04-12 Process for the preparation of respirable particles
DK96910285T DK0820276T3 (da) 1995-04-13 1996-04-12 Fremgangsmåde til fremstilling af respirerbare partikler
EP96910285A EP0820276B1 (en) 1995-04-13 1996-04-12 Process for the preparation of respirable particles
CN96194372A CN1102383C (zh) 1995-04-13 1996-04-12 适于吸入使用的颗粒的制备方法
PCT/SE1996/000479 WO1996032095A1 (en) 1995-04-13 1996-04-12 Process for the preparation of respirable particles
AR33616796A AR001624A1 (es) 1995-04-13 1996-04-12 Procedimiento para la preparacion de particulas respirables
NZ305515A NZ305515A (en) 1995-04-13 1996-04-12 Preparation of pharmaceutical powder for inhalation using an anti-solvent
PT96910285T PT820276E (pt) 1995-04-13 1996-04-12 Processo para a preparacao de particulas respiraveis
US08/669,477 US6221398B1 (en) 1995-04-13 1996-04-12 Process for the preparation of respirable particles
AU53524/96A AU694863B2 (en) 1995-04-13 1996-04-12 Process for the preparation of respirable particles
ES96910285T ES2188750T3 (es) 1995-04-13 1996-04-12 Procedimiento para la preparacion de particulas respirables.
JP8530963A JPH11503448A (ja) 1995-04-13 1996-04-12 吸引可能粒子の製造法
MYPI96001419A MY117344A (en) 1995-04-13 1996-04-13 Process for the preparation of respirable particles.
NO19974557A NO316209B1 (no) 1995-04-13 1997-10-02 Fremgangsmåte for fremstilling av et farmasöytisk pulver for inhalasjon

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9501384A SE9501384D0 (sv) 1995-04-13 1995-04-13 Process for the preparation of respirable particles

Publications (1)

Publication Number Publication Date
SE9501384D0 true SE9501384D0 (sv) 1995-04-13

Family

ID=20397958

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9501384A SE9501384D0 (sv) 1995-04-13 1995-04-13 Process for the preparation of respirable particles

Country Status (22)

Country Link
US (1) US6221398B1 (enExample)
EP (1) EP0820276B1 (enExample)
JP (1) JPH11503448A (enExample)
CN (1) CN1102383C (enExample)
AR (1) AR001624A1 (enExample)
AT (1) ATE230257T1 (enExample)
AU (1) AU694863B2 (enExample)
CA (1) CA2217062A1 (enExample)
DE (1) DE69625589T2 (enExample)
DK (1) DK0820276T3 (enExample)
ES (1) ES2188750T3 (enExample)
IL (1) IL117841A (enExample)
IN (1) IN185119B (enExample)
MY (1) MY117344A (enExample)
NO (1) NO316209B1 (enExample)
NZ (1) NZ305515A (enExample)
PT (1) PT820276E (enExample)
SA (1) SA96160645B1 (enExample)
SE (1) SE9501384D0 (enExample)
TW (1) TW492877B (enExample)
WO (1) WO1996032095A1 (enExample)
ZA (1) ZA962596B (enExample)

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9501384D0 (sv) 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
SE9701956D0 (sv) 1997-05-23 1997-05-23 Astra Ab New composition of matter
SK184799A3 (en) * 1997-06-27 2000-06-12 Astra Ab New combination of antiasthma medicaments
SE9704186D0 (sv) * 1997-11-14 1997-11-14 Astra Ab New composition of matter
GB9806477D0 (en) * 1998-03-26 1998-05-27 Glaxo Group Ltd Improved crystals
GB2341120B (en) 1998-09-04 2002-04-17 Aea Technology Plc Controlling uniformity of crystalline precipitates
SE9803770D0 (sv) * 1998-11-05 1998-11-05 Astra Ab Dry powder pharmaceutical formulation
SE9804001D0 (sv) * 1998-11-23 1998-11-23 Astra Ab New process
GB9826284D0 (en) * 1998-12-01 1999-01-20 Rhone Poulence Rorer Limited Process
GB9826286D0 (en) * 1998-12-01 1999-01-20 Rhone Poulence Rorer Limited Process
GB9828721D0 (en) * 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process
GB9905512D0 (en) * 1999-03-10 1999-05-05 Smithkline Beecham Plc Process
GB9919693D0 (en) * 1999-08-19 1999-10-20 Rhone Poulenc Rorer Ltd Process
CZ20011726A3 (cs) 2000-05-26 2002-02-13 Pfizer Products Inc. Způsob reakční krystalizace, který umoľňuje řídit velikost částic
GB0016040D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
GB0015981D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
GB0016002D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
US6884436B2 (en) * 2000-12-22 2005-04-26 Baxter International Inc. Method for preparing submicron particle suspensions
US6607784B2 (en) 2000-12-22 2003-08-19 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US9700866B2 (en) * 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US6977085B2 (en) 2000-12-22 2005-12-20 Baxter International Inc. Method for preparing submicron suspensions with polymorph control
US7193084B2 (en) 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
US20040256749A1 (en) * 2000-12-22 2004-12-23 Mahesh Chaubal Process for production of essentially solvent-free small particles
US6951656B2 (en) 2000-12-22 2005-10-04 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
CA2445146A1 (en) 2001-05-05 2002-11-14 Accentus Plc Formation of small crystals
DE10137017A1 (de) * 2001-07-30 2003-02-20 Basf Ag Kristallisationsverfahren zur Einstellung kleiner Partikel
WO2003032951A1 (en) * 2001-08-29 2003-04-24 Dow Global Technologies Inc. A process for preparing crystalline drug particles by means of precipitation
MXPA04002446A (es) * 2001-09-26 2004-07-23 Baxter Int Preparacion de nanoparticulas de tamano de submicras mediante dispersion y remocion de la fase liquida o solvente.
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
US7931022B2 (en) * 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
US7112340B2 (en) 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
US20030140920A1 (en) * 2001-10-26 2003-07-31 Dey L.P. Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
US20030191151A1 (en) * 2001-10-26 2003-10-09 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US20030203930A1 (en) * 2001-10-26 2003-10-30 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
JP2003221335A (ja) 2001-10-26 2003-08-05 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
EP1476201B1 (en) * 2002-02-19 2008-12-24 Resolution Chemicals Limited Solvent-based sterilisation of steroids
DE10214031A1 (de) * 2002-03-27 2004-02-19 Pharmatech Gmbh Verfahren zur Herstellung und Anwendung von Mikro- und Nanoteilchen durch aufbauende Mikronisation
FI20020857A7 (fi) * 2002-05-07 2003-11-08 Focus Inhalation Oy Amorfisen aineen muuntaminen vastaavaksi kiteiseksi aineeksi spraykuivaamalla ja käyttämällä kiteistä spraykuivattua ainetta lääkevalmisteissa
EP1531794B1 (en) * 2002-06-28 2017-05-10 Civitas Therapeutics, Inc. Inhalable epinephrine
GB0216700D0 (en) 2002-07-18 2002-08-28 Astrazeneca Ab Process
US20040023935A1 (en) * 2002-08-02 2004-02-05 Dey, L.P. Inhalation compositions, methods of use thereof, and process for preparation of same
US20040028746A1 (en) * 2002-08-06 2004-02-12 Sonke Svenson Crystalline drug particles prepared using a controlled precipitation (recrystallization) process
US20040028747A1 (en) * 2002-08-06 2004-02-12 Tucker Christopher J. Crystalline drug particles prepared using a controlled precipitation process
CN1694689A (zh) * 2002-09-30 2005-11-09 阿库斯菲尔公司 供吸入的缓释多孔微粒
US20040109826A1 (en) * 2002-12-06 2004-06-10 Dey, L.P. Stabilized albuterol compositions and method of preparation thereof
US20040121003A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
US6962006B2 (en) * 2002-12-19 2005-11-08 Acusphere, Inc. Methods and apparatus for making particles using spray dryer and in-line jet mill
US20060241130A1 (en) * 2003-01-31 2006-10-26 Ehud Keinan Anti-inflammatory compositions and uses thereof
GB0302673D0 (en) 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
EP1610878B1 (en) * 2003-02-21 2014-09-03 University Of Bath Process for the production of particles
US7041144B2 (en) * 2003-03-04 2006-05-09 Five Star Technologies, Inc. Hydrodynamic cavitation crystallization process
US7511079B2 (en) * 2003-03-24 2009-03-31 Baxter International Inc. Methods and apparatuses for the comminution and stabilization of small particles
KR20060006949A (ko) * 2003-04-29 2006-01-20 아크조 노벨 엔.브이. 반용매 고화 방법
US20060275219A1 (en) * 2003-06-10 2006-12-07 Taisho Pharmaceutical Co., Ltd. Radial spherical crystallization product, process for producing the same, and dry powder preparation containing the crystallization product
SE0302029D0 (sv) * 2003-07-07 2003-07-07 Astrazeneca Ab Novel process
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
JP2007520555A (ja) * 2004-02-05 2007-07-26 バクスター・インターナショナル・インコーポレイテッド 自己安定化剤の使用により調製された分散剤
TWI341836B (en) 2004-03-11 2011-05-11 Theravance Inc Biphenyl compounds useful as muscarinic receptor antagonists
WO2005105278A2 (en) * 2004-05-05 2005-11-10 Akzo Nobel N.V. Antisolvent emulsion solidification process
US7498445B2 (en) * 2004-05-05 2009-03-03 Renopharm Ltd. Thiazole-based nitric oxide donors capable of releasing two or more nitric oxide molecules and uses thereof
EP1753734A1 (en) * 2004-05-05 2007-02-21 Renopharm Ltd. Nitric oxide donors and uses thereof
US8134010B2 (en) * 2004-05-05 2012-03-13 Renopharm Ltd. Thiazole-based nitric oxide donors having aryl substituent(s) and uses thereof
US7968575B2 (en) * 2004-05-05 2011-06-28 Renopharm Ltd. Nitric oxide donors and uses thereof
US20060009435A1 (en) * 2004-06-23 2006-01-12 Joseph Kaspi Synthesis and powder preparation of fluticasone propionate
JP2008510015A (ja) 2004-08-16 2008-04-03 セラヴァンス, インコーポレーテッド β2アドレナリン作用性レセプターアゴニスト活性およびムスカリン性レセプターアンタゴニスト活性を有する化合物
WO2006045795A2 (en) * 2004-10-29 2006-05-04 Akzo Nobel N.V. Processes involving the use of antisolvent crystallization
US20060120972A1 (en) * 2004-11-09 2006-06-08 Peter Engels 9-(N-methyl-piperidyliden-4)-thioxanthene for treatment of pulmonary hypertension
DE102005011786A1 (de) 2005-03-11 2006-09-14 Pharmasol Gmbh Verfahren zur Herstellung ultrafeiner Submicron-Suspensionen
CN101312713A (zh) * 2005-03-18 2008-11-26 纳米材料科技有限公司 可吸入的药物
WO2006113309A1 (en) 2005-04-15 2006-10-26 Dr. Reddy's Laboratories Ltd. Lacidipine particles
US20060280787A1 (en) * 2005-06-14 2006-12-14 Baxter International Inc. Pharmaceutical formulation of the tubulin inhibitor indibulin for oral administration with improved pharmacokinetic properties, and process for the manufacture thereof
AU2006272438B2 (en) * 2005-07-15 2011-08-04 Map Pharmaceuticals, Inc. Method of particle formation
CN101262846A (zh) * 2005-07-15 2008-09-10 Map药物公司 在离散的吸入粒子中结合的多种活性药物成分及其制剂
EP1912730A2 (en) * 2005-07-28 2008-04-23 Isp Investments Inc. Method to improve characteristics of spray dried powders and granulated materials, and the products thereby produced
US20070099883A1 (en) * 2005-10-07 2007-05-03 Cheryl Lynn Calis Anhydrous mometasone furoate formulation
AU2006315177A1 (en) * 2005-11-15 2007-05-24 Baxter Healthcare S.A. Compositions of lipoxygenase inhibitors
WO2007070843A2 (en) * 2005-12-15 2007-06-21 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for oral administration
US20070178166A1 (en) * 2005-12-15 2007-08-02 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration
US7913223B2 (en) * 2005-12-16 2011-03-22 Dialogic Corporation Method and system for development and use of a user-interface for operations, administration, maintenance and provisioning of a telecommunications system
US20080085315A1 (en) * 2006-10-10 2008-04-10 John Alfred Doney Amorphous ezetimibe and the production thereof
WO2008057048A1 (en) * 2006-11-09 2008-05-15 Nanomaterials Technology Pte Ltd Nano & micro-sized particles of statin compounds and process for forming same
WO2008076780A2 (en) * 2006-12-14 2008-06-26 Isp Investments Inc. Amorphous valsartan and the production thereof
WO2008080037A2 (en) * 2006-12-21 2008-07-03 Isp Investments Inc. Carotenoids of enhanced bioavailability
US20090152176A1 (en) * 2006-12-23 2009-06-18 Baxter International Inc. Magnetic separation of fine particles from compositions
US20080181961A1 (en) * 2007-01-26 2008-07-31 Isp Investments, Inc. Amorphous oxcarbazepine and the production thereof
JP5508859B2 (ja) * 2007-01-26 2014-06-04 アイエスピー インヴェストメンツ インコーポレイテッド 噴霧乾燥製品を製造するための調剤処理方法
US8722736B2 (en) * 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) * 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US20080293814A1 (en) * 2007-05-22 2008-11-27 Deepak Tiwari Concentrate esmolol
EP2191821A1 (en) * 2008-11-26 2010-06-02 CHIESI FARMACEUTICI S.p.A. Microparticles comprising a salt of 8-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]-2(1H)-quinolinone having improved adhesion properties for dry powder inhalation
EP3620154A1 (en) * 2009-02-06 2020-03-11 University Of Southern California Therapeutic compositions comprising monoterpenes
US20100291221A1 (en) * 2009-05-15 2010-11-18 Robert Owen Cook Method of administering dose-sparing amounts of formoterol fumarate-budesonide combination particles by inhalation
US20100298602A1 (en) * 2009-05-19 2010-11-25 Massachusetts Institute Of Technology Systems and methods for microfluidic crystallization
US20100294986A1 (en) * 2009-05-19 2010-11-25 Massachusetts Institute Of Technology Supercritical fluid facilitated particle formation in microfluidic systems
SG178036A1 (en) 2009-07-15 2012-03-29 Theravance Inc Crystalline freebase forms of a biphenyl compound
CN102573886A (zh) * 2009-09-17 2012-07-11 相互制药公司 用抗病毒剂治疗哮喘的方法
KR20150043548A (ko) 2009-10-01 2015-04-22 앱탈리스 파마테크, 인코포레이티드 경구 투여용 코르티코스테로이드 조성물
CN102711743A (zh) 2009-10-22 2012-10-03 Api起源有限责任公司 含有黄酮类的组合物的制备和使用方法
CN104744215B (zh) 2010-03-03 2019-03-15 尼昂克技术公司 包含单萜的药物组合物
CN101849910B (zh) * 2010-05-18 2012-02-22 重庆华邦制药股份有限公司 一种二丙酸倍他米松微粒的制备方法
US20160038600A1 (en) 2012-08-03 2016-02-11 Neonc Technologies Inc. Pharmaceutical compositions comprising poh derivatives
US9499461B2 (en) 2010-08-27 2016-11-22 Neonc Technologies, Inc. Pharmaceutical compositions comprising POH derivatives
AU2011305566A1 (en) 2010-09-22 2013-05-02 Map Pharmaceuticals, Inc. Aerosol composition for administering drugs
ES3056006T3 (en) 2010-12-17 2026-02-17 Univ Southern California Methods and devices for using isoperillyl alcohol
CN102134236B (zh) * 2011-04-15 2013-07-24 北方民族大学 微细克拉霉素粉体的制备方法
EP2729480A4 (en) * 2011-07-08 2014-12-31 Pfizer Ltd PROCESS FOR THE PREPARATION OF FLUTICASONE PROPIONATE, FORM 1
KR102017915B1 (ko) 2011-10-11 2019-09-03 키에시 파르마슈티시 엣스. 피. 에이. 지방산으로 코팅된 베타-작용제의 결정미세입자
DE102012221219B4 (de) * 2012-11-20 2014-05-28 Jesalis Pharma Gmbh Verfahren zur Vergrößerung der Partikelgröße kristalliner Wirkstoff-Mikropartikel
JP6560986B2 (ja) 2013-03-15 2019-08-14 ヴェローナ ファーマ ピーエルシー 複合製剤
WO2015034678A2 (en) 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
ES2773142T3 (es) 2014-05-12 2020-07-09 Verona Pharma Plc Nuevo tratamiento
CA2954287C (en) * 2014-07-08 2020-12-22 Amphastar Pharmaceuticals, Inc. Methods of preparing inhalable micronized insulin for pulmonary delivery
WO2016130800A2 (en) 2015-02-12 2016-08-18 Neonc Technologies Inc. Pharmaceutical compositions comprising perillyl alcohol derivatives
US10322168B2 (en) 2016-01-07 2019-06-18 Amphastar Pharmaceuticals, Inc. High-purity inhalable particles of insulin and insulin analogues, and high-efficiency methods of manufacturing the same
TWI777515B (zh) 2016-08-18 2022-09-11 美商愛戴爾製藥股份有限公司 治療嗜伊紅性食道炎之方法
CN110267538B (zh) 2016-11-30 2022-04-19 尼昂克技术公司 紫苏醇-3-溴丙酮酸缀合物和治疗癌症的方法
JP7325425B2 (ja) 2018-02-08 2023-08-14 ネオンク テクノロジーズ インク. 血液脳関門を透過性にする方法
WO2020205539A1 (en) 2019-03-29 2020-10-08 Vizuri Health Sciences Consumer Healthcare, Inc. Compositions and methods for the prevention and treatment of radiation dermatitis, eczema, burns, wounds and certain cancers
US12691128B2 (en) 2019-10-01 2026-07-28 Ellodi Pharmaceuticals, L.P. Methods of treating eosinophilic esophagitis and reducing candidiasis
CN114262316A (zh) * 2021-12-24 2022-04-01 嘉应学院 纳米橙皮素、其制备方法及所用双匀浆空化射流系统
CN117582373A (zh) * 2023-08-15 2024-02-23 中国药科大学 一种类球形无载体妥布霉素粉雾剂颗粒的湍流强化可控制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1282405C (en) * 1984-05-21 1991-04-02 Michael R. Violante Method for making uniformly sized particles from water-insoluble organic compounds
US4826689A (en) * 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds
DE68907062T2 (de) * 1988-10-05 1993-10-07 Upjohn Co Feinverteiltes feste kristalline pulver durch niederschlag in einem anti-lösungsmittel.
GB9001635D0 (en) * 1990-01-24 1990-03-21 Ganderton David Aerosol carriers
JP3282731B2 (ja) * 1990-06-15 2002-05-20 メルク エンド カムパニー インコーポレーテッド 結晶の構造および大きさを改良する結晶化方法
SE9302777D0 (sv) * 1993-08-27 1993-08-27 Astra Ab Process for conditioning substances
US5639441A (en) * 1992-03-06 1997-06-17 Board Of Regents Of University Of Colorado Methods for fine particle formation
SE9501384D0 (sv) 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles

Also Published As

Publication number Publication date
SA96160645B1 (ar) 2005-07-05
NO974557L (no) 1997-10-02
AU5352496A (en) 1996-10-30
IL117841A0 (en) 1996-08-04
IN185119B (enExample) 2000-11-18
CN1102383C (zh) 2003-03-05
MY117344A (en) 2004-06-30
ES2188750T3 (es) 2003-07-01
PT820276E (pt) 2003-04-30
ATE230257T1 (de) 2003-01-15
JPH11503448A (ja) 1999-03-26
NZ305515A (en) 1999-03-29
US6221398B1 (en) 2001-04-24
DE69625589D1 (de) 2003-02-06
EP0820276A1 (en) 1998-01-28
AU694863B2 (en) 1998-07-30
ZA962596B (en) 1996-10-14
CA2217062A1 (en) 1996-10-17
AR001624A1 (es) 1997-11-26
EP0820276B1 (en) 2003-01-02
IL117841A (en) 2004-01-04
CN1186428A (zh) 1998-07-01
NO316209B1 (no) 2003-12-29
DK0820276T3 (da) 2003-03-17
WO1996032095A1 (en) 1996-10-17
DE69625589T2 (de) 2003-09-25
TW492877B (en) 2002-07-01
NO974557D0 (no) 1997-10-02

Similar Documents

Publication Publication Date Title
MY117344A (en) Process for the preparation of respirable particles.
BR0317595A (pt) Método e aparelho para produzir partìculas, método para produzir uma mistura de pó seco e composição farmacêutica
DE3686025D1 (de) Verfahren und system zum einatmen von liposomen.
DE69102602D1 (de) Vorrichtung zum Mundinhalieren von aerosolförmigen Arzneimitteln.
CA2335065A1 (en) Pharmaceutical formulations for aerosols with two or more active substances
EA200401006A1 (ru) Аэрозольные препараты для внутрилёгочного введения лекарств с получением системного действия
BR9909394A (pt) Composição de aerossol, composição farmacêutica, recipiente, dispositivo de inalação, processo para preparar uma composição de aerossol, mistura de um primeiro material particulado, e, processo para administrar um medicamento particulado
CO4180565A1 (es) Procedimiento y dispositivo para la produccion de un aerosol a partir de una sustancia en polvo
NZ294897A (en) Manufacture of medicaments by high-shear mixing drug in molten or softened carrier
HUT64232A (en) Process for the production of the medical agent by the extraction from tanacetum parthenium and for the production of medical prepartives containing it
DE60031184D1 (de) Pharmazeutische Zusammensetzung enthaltend Fenofibrat und Verfahren zu deren Herstellung
PT1214129E (pt) Processo para a preparacao de substancias medicinais finas
ATE336231T1 (de) Verfahren zur herstellung kristalliner arzneimittelteilchen durch ausfällung
AU8063994A (en) Method for preparing a viral aerosol
BR0207570A (pt) Aparelho para formação de partìculas micronizadas e submicronizadas de uma substância, bocal para a introdução de uma solução de uma substância e de um fluido supercrìtico em um vaso de formação de partìculas, e, processo para formação de partìculas micronizadas e submicronizadas de uma substância
FI952294A0 (fi) Menetelmä taksaanijohdannaisten valmistamiseksi, näin saadut uudet taksaanit ja niitä sisältävät kasvainvastaiset ja leukemiavastaiset koostumukset
SE8800080L (sv) Laekemedelskomposition
HUT45537A (en) Process for producing delta-22 derivatives of ll-f 28249 compounds and pharmaceutical compositions containing them as active components, and insecticide compositions
ES2018378A6 (es) Procedimiento para preparar eteres ciclicos sustituidos con nitratoalquilo.
HUT58282A (en) Process for producing new, cyclic ketone derivatives and pharmaceutical compositions containing them as active components
JPS5225015A (en) Process for preparing fine granular drugs
SE9500251L (sv) Förfarande och aggregat för beredning av en gasblandning avsedd för medicinsk behandling via andningsvägarna
JPS525769A (en) Preparation of 3-substituted pyrolidine derivatives
HUT52071A (en) Process for producing 1-amino-alkyl-3-oxy-4-aryl-1,3,4,5-tetrahydro-2h-1,3-benzodiazepin-2-one derivatives and pharmaceutical compositions containing them as active components
AU6766490A (en) New sulphate derivative of galactan extracted from klebsiella, preparation process, use as medicaments and pharmaceutical compositions containing it