SE9001402L - Foerfarande foer framstaellning av kinazolinderivattives - Google Patents
Foerfarande foer framstaellning av kinazolinderivattivesInfo
- Publication number
- SE9001402L SE9001402L SE9001402A SE9001402A SE9001402L SE 9001402 L SE9001402 L SE 9001402L SE 9001402 A SE9001402 A SE 9001402A SE 9001402 A SE9001402 A SE 9001402A SE 9001402 L SE9001402 L SE 9001402L
- Authority
- SE
- Sweden
- Prior art keywords
- general formula
- lower alkyl
- group
- procedures
- preparing
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000002541 isothioureas Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical class N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 abstract 1
- 150000003246 quinazolines Chemical class 0.000 abstract 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU193089A HU203333B (en) | 1989-04-21 | 1989-04-21 | Process for producing n-cyano-carboxamidine derivatives |
| HU193189A HU203342B (en) | 1989-04-21 | 1989-04-21 | Process for producing quinazoline deivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE9001402D0 SE9001402D0 (sv) | 1990-04-20 |
| SE9001402L true SE9001402L (sv) | 1990-10-22 |
Family
ID=26317437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9001402A SE9001402L (sv) | 1989-04-21 | 1990-04-20 | Foerfarande foer framstaellning av kinazolinderivattives |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPH02292282A (en, 2012) |
| KR (1) | KR900016194A (en, 2012) |
| AT (1) | AT398075B (en, 2012) |
| BG (1) | BG91821A (en, 2012) |
| CA (2) | CA2028953A1 (en, 2012) |
| CH (1) | CH681300A5 (en, 2012) |
| DK (1) | DK99090A (en, 2012) |
| ES (1) | ES2019826A6 (en, 2012) |
| FI (1) | FI902002A7 (en, 2012) |
| GB (1) | GB2231571B (en, 2012) |
| GR (1) | GR900100294A (en, 2012) |
| IT (1) | IT1241128B (en, 2012) |
| PL (1) | PL162976B1 (en, 2012) |
| RU (1) | RU1838309C (en, 2012) |
| SE (1) | SE9001402L (en, 2012) |
| YU (1) | YU70890A (en, 2012) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2077252C (en) * | 1992-08-31 | 2001-04-10 | Khashayar Karimian | Methods of making ureas and guanidines, and intermediates therefor |
| ES2096518B1 (es) * | 1994-03-28 | 1997-12-01 | Grupo Farmaceutico Almirall S | Nuevas anilinas. |
| WO2008015525A2 (en) * | 2006-07-31 | 2008-02-07 | Orchid Chemicals & Pharmaceuticals Limited | An improved process for the preparation of alfuzosin hydrochloride |
| US20100174073A1 (en) | 2007-05-04 | 2010-07-08 | Actavis Group Ptc Ehf | Process for the preparation of alfuzosin and salts thereof |
| US8716476B2 (en) | 2007-08-02 | 2014-05-06 | Cipla Limited | Process for the preparation of alfuzosin hydrochloride |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4026894A (en) * | 1975-10-14 | 1977-05-31 | Abbott Laboratories | Antihypertensive agents |
| US4044135A (en) * | 1975-10-14 | 1977-08-23 | Abbott Laboratories | Antihypertensive agents |
| GB1591490A (en) * | 1977-08-04 | 1981-06-24 | Abbott Lab | 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate |
| US4138561A (en) * | 1977-09-30 | 1979-02-06 | Bristol-Myers Company | Cyanocarboxamidines and quinazoline process |
| FI57751C (fi) * | 1977-10-25 | 1980-10-10 | Fermion Oy | Foerfarande foer framstaellning av 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner med blodtryckssaenkande verkan |
| FI56836C (fi) * | 1977-10-25 | 1980-04-10 | Fermion Oy | 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner |
| FR2421888A1 (fr) * | 1978-02-06 | 1979-11-02 | Synthelabo | Amides d'alkylene-diamines et leur application en therapeutique |
| FI59800C (fi) * | 1979-01-10 | 1981-10-12 | Fermion Oy | Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(furo-2-yl)-piperazin-1-yl)-kinazolin |
| FI67699C (fi) * | 1979-01-31 | 1985-05-10 | Orion Yhtymae Oy | Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan |
| ATE32074T1 (de) * | 1983-11-22 | 1988-02-15 | Heumann Ludwig & Co Gmbh | Verfahren zur herstellung von 4-amino-6,7dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)chinazolin und dessen physiologisch annehmbarer salze. |
-
1990
- 1990-04-11 YU YU00708/90A patent/YU70890A/xx unknown
- 1990-04-19 GR GR900100294A patent/GR900100294A/el unknown
- 1990-04-20 CA CA002028953A patent/CA2028953A1/en not_active Abandoned
- 1990-04-20 CH CH1348/90A patent/CH681300A5/de not_active IP Right Cessation
- 1990-04-20 GB GB9008941A patent/GB2231571B/en not_active Expired - Lifetime
- 1990-04-20 ES ES9001130A patent/ES2019826A6/es not_active Expired - Lifetime
- 1990-04-20 FI FI902002A patent/FI902002A7/fi not_active IP Right Cessation
- 1990-04-20 RU SU904743794A patent/RU1838309C/ru active
- 1990-04-20 JP JP2103239A patent/JPH02292282A/ja active Pending
- 1990-04-20 BG BG091821A patent/BG91821A/bg unknown
- 1990-04-20 PL PL28486090A patent/PL162976B1/pl unknown
- 1990-04-20 DK DK099090A patent/DK99090A/da not_active Application Discontinuation
- 1990-04-20 CA CA2015066A patent/CA2015066A1/xx active Pending
- 1990-04-20 AT AT0093190A patent/AT398075B/de not_active IP Right Cessation
- 1990-04-20 IT IT20092A patent/IT1241128B/it active IP Right Grant
- 1990-04-20 SE SE9001402A patent/SE9001402L/xx not_active Application Discontinuation
- 1990-04-20 KR KR1019900005608A patent/KR900016194A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| RU1838309C (ru) | 1993-08-30 |
| PL162976B1 (pl) | 1994-01-31 |
| GB9008941D0 (en) | 1990-06-20 |
| IT9020092A0 (it) | 1990-04-20 |
| YU70890A (en) | 1992-05-28 |
| ES2019826A6 (es) | 1991-07-01 |
| BG91821A (bg) | 1993-12-24 |
| CA2015066A1 (en) | 1990-10-21 |
| PL284860A1 (en) | 1991-03-11 |
| JPH02292282A (ja) | 1990-12-03 |
| IT1241128B (it) | 1993-12-29 |
| GB2231571B (en) | 1992-09-16 |
| FI902002A7 (fi) | 1990-10-22 |
| CA2028953A1 (en) | 1990-10-22 |
| IT9020092A1 (it) | 1991-10-20 |
| KR900016194A (ko) | 1990-11-12 |
| GB2231571A (en) | 1990-11-21 |
| ATA93190A (de) | 1994-01-15 |
| AT398075B (de) | 1994-09-26 |
| GR900100294A (el) | 1991-09-27 |
| DK99090A (da) | 1990-10-22 |
| CH681300A5 (en, 2012) | 1993-02-26 |
| DK99090D0 (da) | 1990-04-20 |
| SE9001402D0 (sv) | 1990-04-20 |
| FI902002A0 (fi) | 1990-04-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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