SE8900173D0 - Cephalosporin salts and injectable compositions - Google Patents

Cephalosporin salts and injectable compositions

Info

Publication number
SE8900173D0
SE8900173D0 SE8900173A SE8900173A SE8900173D0 SE 8900173 D0 SE8900173 D0 SE 8900173D0 SE 8900173 A SE8900173 A SE 8900173A SE 8900173 A SE8900173 A SE 8900173A SE 8900173 D0 SE8900173 D0 SE 8900173D0
Authority
SE
Sweden
Prior art keywords
salts
injectable compositions
alpha
methyl
cephalosporin salts
Prior art date
Application number
SE8900173A
Other languages
English (en)
Swedish (sv)
Other versions
SE505258C2 (sv
SE8900173L (en
Inventor
M A Kaplan
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22510643&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE8900173(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE8900173D0 publication Critical patent/SE8900173D0/
Publication of SE8900173L publication Critical patent/SE8900173L/
Publication of SE505258C2 publication Critical patent/SE505258C2/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SE8900173A 1988-01-19 1989-01-18 Nya dihydrokloridhydrat av 7-(]0a]-(2aminotiazol-4-yl)-]0a]- (Z)-metoxiiminoacetamido)-3-((1-metylpyrrolidino)-metyl)-3- cefem-4-karboxylsyra i kristallin form SE505258C2 (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/144,899 US4910301A (en) 1985-08-05 1988-01-19 Cefepime cephalosporin salts

Publications (3)

Publication Number Publication Date
SE8900173D0 true SE8900173D0 (sv) 1989-01-18
SE8900173L SE8900173L (en) 1989-01-18
SE505258C2 SE505258C2 (sv) 1997-07-21

Family

ID=22510643

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8900173A SE505258C2 (sv) 1988-01-19 1989-01-18 Nya dihydrokloridhydrat av 7-(]0a]-(2aminotiazol-4-yl)-]0a]- (Z)-metoxiiminoacetamido)-3-((1-metylpyrrolidino)-metyl)-3- cefem-4-karboxylsyra i kristallin form

Country Status (32)

Country Link
US (1) US4910301A ( )
JP (1) JPH0725768B2 ( )
KR (1) KR950003612B1 ( )
AT (1) AT399878B ( )
AU (1) AU615509B2 ( )
BE (1) BE1002749A5 ( )
CA (1) CA1298288C ( )
CY (1) CY1663A ( )
CZ (1) CZ281602B6 ( )
DD (2) DD284807A5 ( )
DE (1) DE3901359A1 ( )
DK (1) DK162054C ( )
EG (1) EG18749A ( )
ES (1) ES2012948A6 ( )
FI (1) FI86854C ( )
FR (1) FR2626003B1 ( )
GB (1) GB2213819B ( )
GR (1) GR1001218B ( )
HK (1) HK72292A ( )
HU (1) HU205940B ( )
IE (1) IE67447B1 ( )
IT (1) IT1229528B ( )
LU (1) LU87432A1 ( )
NL (1) NL192266C ( )
NZ (1) NZ227605A ( )
OA (1) OA09227A ( )
PT (1) PT89474B ( )
SE (1) SE505258C2 ( )
SG (1) SG75492G ( )
SK (1) SK281768B6 ( )
YU (1) YU221188A ( )
ZA (1) ZA89407B ( )

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
EP0376185B1 (en) * 1988-12-27 1994-08-17 Chugai Seiyaku Kabushiki Kaisha Process for purification of 1,2-bis(nicotinamido)propane
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
DE3919259A1 (de) * 1989-06-13 1990-12-20 Hoechst Ag Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung
US5698703A (en) * 1991-09-10 1997-12-16 Bristol-Myers Squibb Company Syn-isomer of thiazolyl intermediate and process for the preparation thereof
IL103110A (en) * 1991-09-10 1997-04-15 Bristol Myers Squibb Co Anhydrous process for preparing cefepime dihydrochloride hydrate
YU81692A (sh) * 1991-09-10 1995-03-27 Bristol-Myers Co. Postupak za proizvodnju cefalosporinskog antibiotika
US5594129A (en) * 1991-09-10 1997-01-14 Bristol-Myers Squibb Company Process for the preparation of a cephalosporin antibiotic
CA2099692C (en) * 1992-07-24 2003-09-30 Gary M. F. Lim Process for preparing cephalosporin intermediates
US5391729A (en) * 1992-09-08 1995-02-21 Bristol-Myers Squibb Company Crystalline dihydrate of a cephalosporin salt
US5401842A (en) * 1992-09-08 1995-03-28 Bristol-Myers Squibb Company Injectable compositions of a cephalosporin dihydrate salt
CA2101571A1 (en) * 1992-09-08 1994-03-09 Elizabeth A. Garofalo Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
JPH0840907A (ja) 1994-08-03 1996-02-13 Meiji Seika Kaisha Ltd セファロスポリン注射剤
WO2005094800A2 (en) * 2004-03-31 2005-10-13 Lupin Ltd. A co-precipitated cefepime composition and process for preparation thereof
US20070111980A1 (en) * 2004-07-16 2007-05-17 Bandi Parthasaradhi Reddy Process for preparing pure cephalosporine intermediates
ITMI20051684A1 (it) * 2005-09-13 2007-03-14 Harvest Lodge Ltd Procedimento per la produzione del dicloridrato di amminoacidi
ITMI20060422A1 (it) * 2006-03-09 2007-09-10 Harvest Lodge Ltd Procedimento diretto per la produzione del dicloridrato di un amminoacido
US8151846B2 (en) * 2006-12-15 2012-04-10 Center Line Wheel Corporation Wheel having inner bead-lock
AR077320A1 (es) * 2009-07-20 2011-08-17 Intervet Int Bv Metodo para la preparacion de particulas de cefquinoma y formulaciones farmaceuticas que las comprenden.
CN103304580B (zh) * 2013-06-09 2014-07-09 四川省惠达药业有限公司 一种盐酸头孢吡肟化合物、其制备方法及其药物组合物
WO2017096472A1 (en) * 2015-12-10 2017-06-15 Naeja-Rgm Pharmaceuticals Inc. Cephem compounds, their production and use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029655A (en) * 1975-04-11 1977-06-14 Eli Lilly And Company Method of preparing stable sterile crystalline cephalosporins for parenteral administration
JPS55151588A (en) * 1979-05-14 1980-11-26 Takeda Chem Ind Ltd Preparation of cephalosporin salt crystal
IT1145686B (it) * 1979-05-25 1986-11-05 Glaxo Group Ltd Intermedi per la preparazione di antibiotici cefalosporinici e procedimento per prepararli
US4329453A (en) * 1979-10-02 1982-05-11 Glaxo Group Limited Cephalosporin antibiotic
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
CA1213882A (en) * 1982-03-04 1986-11-12 Jun Okumura Cephalosporins
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
US4537959A (en) * 1984-03-26 1985-08-27 Eli Lilly And Company Crystalline cephalosporin antibiotic salt
US4751295A (en) * 1984-04-09 1988-06-14 Bristol-Myers Company Cephalosporin derivatives
US4749694A (en) * 1984-04-26 1988-06-07 Merck & Co., Inc. Novel lysine esters used as absorption
FR2585705B1 (fr) * 1985-08-05 1989-01-13 Bristol Myers Co Sels de cephalosporine et compositions injectables
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
US4791196A (en) * 1986-09-26 1988-12-13 Sankyo Company Limited Crystalline cephem carboxylic acid addition salt

Also Published As

Publication number Publication date
SE505258C2 (sv) 1997-07-21
GB8901073D0 (en) 1989-03-15
HUT50347A (en) 1990-01-29
OA09227A (fr) 1992-06-30
DK20789A (da) 1989-07-20
LU87432A1 (fr) 1989-08-30
FI86854C (fi) 1992-10-26
PT89474B (pt) 1993-12-31
CY1663A (en) 1993-05-14
JPH0725768B2 (ja) 1995-03-22
NZ227605A (en) 1991-06-25
EG18749A (en) 1993-12-30
SK24389A3 (en) 2000-12-11
ATA8589A (de) 1994-12-15
GR1001218B (el) 1993-06-21
AU2862389A (en) 1989-07-20
CZ24389A3 (en) 1996-08-14
US4910301A (en) 1990-03-20
DK20789D0 (da) 1989-01-18
IT8947539A0 (it) 1988-01-17
ZA89407B (en) 1989-09-27
ES2012948A6 (es) 1990-04-16
DK162054C (da) 1992-02-10
IT1229528B (it) 1991-09-04
KR890011895A (ko) 1989-08-23
CA1298288C (en) 1992-03-31
DD284807A5 (de) 1990-11-28
IE890144L (en) 1989-07-19
YU221188A (en) 1990-04-30
SK281768B6 (sk) 2001-07-10
GB2213819A (en) 1989-08-23
GB2213819B (en) 1991-11-27
BE1002749A5 (fr) 1991-05-28
DD283397A5 (de) 1990-10-10
FI890213A (fi) 1989-07-20
FR2626003B1 (fr) 1992-10-16
HU205940B (en) 1992-07-28
JPH029885A (ja) 1990-01-12
DE3901359A1 (de) 1989-10-05
NL192266B (nl) 1996-12-02
FR2626003A1 (fr) 1989-07-21
IE67447B1 (en) 1996-04-03
FI86854B (fi) 1992-07-15
SE8900173L (en) 1989-01-18
HK72292A (en) 1992-10-02
NL8900111A (nl) 1989-08-16
CZ281602B6 (cs) 1996-11-13
FI890213A0 (fi) 1989-01-16
AT399878B (de) 1995-08-25
AU615509B2 (en) 1991-10-03
DK162054B (da) 1991-09-09
SG75492G (en) 1992-10-02
DE3901359C2 ( ) 1992-04-30
KR950003612B1 (ko) 1995-04-17
NL192266C (nl) 1997-04-03
PT89474A (pt) 1990-02-08

Similar Documents

Publication Publication Date Title
SE8900173D0 (sv) Cephalosporin salts and injectable compositions
NO872770L (no) Acylderivater.
EP0401857A3 (en) Fenamate 1,3,4-thiadiazoles and 1,3,4-oxadiazoles as antiinflammatory agents
FI881040A (fi) Foerfarande foer framstaellning av kristallisk cefadroxil-monohydrat.
EP0376724A3 (en) Cephalosporin compounds
DK155945C (da) Analogifremgangsmaade til fremstilling af 7-beta-oealfa-syn--methoxyimino-alfa-(2-aminothiazol-4-yl)acetamidoaa-3-oe(1,2,3-thiadiazol-5-ylthio)methylaa-3-cephem-4-carboxylsyre samt i thiadiazolringens 4-stilling substituerede c1-c6-alkylderivater og fysiologisk acceptable salte deraf.
DE3770355D1 (de) Injektionsloesung von cephalosporinen.
EP0238061A3 (en) Cephalosporin derivatives, processes for their preparation and antibacterial agents
DE68922629D1 (de) Ceftazidim-Dihydrochlorid-Ameisensäuresolvate.
EP0377987A3 (en) Acylation process for obtaining cephalosporin derivatives
NO884486L (no) Fremgangsmaate for fremstilling av cefalosporinderivater med forbedrede farmakokinetika.
DE3587915D1 (de) Verfahren zur Herstellung von Cephalosporinen.
ATA294388A (de) Kristallines, schwerloesliches hydrojodisadditionssalz von 7-amino-3-(4-carbamoyl-1chinuclidinium)methyl-3-cephem-4-carboxylat
JPS52108994A (en) Antibiotics of cephalosporin series
JPS5325590A (en) 7-(n-substituted alkanoyl-2-phenylglycineamide)-cephalosporanic acid derivatives
IE44435L (en) 1,3,4-thiadiazole derivatives
CA1270833C (en) 2,5-PYRROLIDINEDIONE DERIVATIVES USEFUL AS ANTI-ARHYTMIZING AGENTS
IT7920115A0 (it) Procedimento per la produzione di antibiotici derivati dall'acido 7-ammino cefalosporanico.
JPS5289690A (en) 7-(alpha-(4-hydroxyl-1,5-naphthyridine-3-carboxyamino)-alpha-phenylacetamide) cephalosporin

Legal Events

Date Code Title Description
NUG Patent has lapsed