SE8505922D0 - Construction of an igg binding protein to facilitate downstream processing using protein engineering - Google Patents
Construction of an igg binding protein to facilitate downstream processing using protein engineeringInfo
- Publication number
- SE8505922D0 SE8505922D0 SE8505922A SE8505922A SE8505922D0 SE 8505922 D0 SE8505922 D0 SE 8505922D0 SE 8505922 A SE8505922 A SE 8505922A SE 8505922 A SE8505922 A SE 8505922A SE 8505922 D0 SE8505922 D0 SE 8505922D0
- Authority
- SE
- Sweden
- Prior art keywords
- recombinant dna
- protein
- sequence
- fragment
- dna molecule
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 238000010276 construction Methods 0.000 title 1
- 238000011143 downstream manufacturing Methods 0.000 title 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 7
- 102000053602 DNA Human genes 0.000 abstract 4
- 239000012634 fragment Substances 0.000 abstract 4
- 108020004705 Codon Proteins 0.000 abstract 2
- OQCPATDFWYYDDX-HGNGGELXSA-N Ala-Gln-His Chemical compound C[C@H](N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O OQCPATDFWYYDDX-HGNGGELXSA-N 0.000 abstract 1
- VAWNQIGQPUOPQW-ACZMJKKPSA-N Asp-Glu-Ala Chemical compound [H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(O)=O VAWNQIGQPUOPQW-ACZMJKKPSA-N 0.000 abstract 1
- 108020004414 DNA Proteins 0.000 abstract 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- 108010076504 Protein Sorting Signals Proteins 0.000 abstract 1
- 108010088160 Staphylococcal Protein A Proteins 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 229940027941 immunoglobulin g Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000013600 plasmid vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8505922A SE8505922D0 (sv) | 1985-12-13 | 1985-12-13 | Construction of an igg binding protein to facilitate downstream processing using protein engineering |
| ES198686850416T ES2046177T3 (es) | 1985-12-13 | 1986-12-02 | Construccion de una proteina enlazante a igg para facilitar el tratamiento aguas abajo utilizando ingenieria de proteinas. |
| AT86850416T ATE80180T1 (de) | 1985-12-13 | 1986-12-02 | Herstellung eines igg-bindenden proteins zum erleichtern der weiterverarbeitung mittels ''protein-engineering''. |
| EP86850416A EP0230869B1 (en) | 1985-12-13 | 1986-12-02 | Construction of an igg binding protein to facilitate downstream processing using protein engineering |
| DE8686850416T DE3686646T2 (de) | 1985-12-13 | 1986-12-02 | Herstellung eines igg-bindenden proteins zum erleichtern der weiterverarbeitung mittels "protein-engineering". |
| AU66331/86A AU600244B2 (en) | 1985-12-13 | 1986-12-09 | Construction of an IgG binding protein to facilitate downstream processing using protein engineering |
| JP61296509A JPH0811069B2 (ja) | 1985-12-13 | 1986-12-12 | 蛋白質工学を用いるダウンストリ−ムプロセツシングを促進するためのIgG結合性蛋白質の構成 |
| DK600486A DK600486A (da) | 1985-12-13 | 1986-12-12 | Igg-bindingsprotein |
| CA000525167A CA1311430C (en) | 1985-12-13 | 1986-12-12 | Construction of an igg binding protein to facilitate downstream processing using protein engineering |
| US07/594,564 US5143844A (en) | 1985-12-13 | 1990-10-09 | Construction of an igg binding protein to facilitate downstream processing using protein engineering |
| GR920402499T GR3006178T3 (https=) | 1985-12-13 | 1992-11-05 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8505922A SE8505922D0 (sv) | 1985-12-13 | 1985-12-13 | Construction of an igg binding protein to facilitate downstream processing using protein engineering |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE8505922D0 true SE8505922D0 (sv) | 1985-12-13 |
Family
ID=20362468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8505922A SE8505922D0 (sv) | 1985-12-13 | 1985-12-13 | Construction of an igg binding protein to facilitate downstream processing using protein engineering |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5143844A (https=) |
| EP (1) | EP0230869B1 (https=) |
| JP (1) | JPH0811069B2 (https=) |
| AT (1) | ATE80180T1 (https=) |
| AU (1) | AU600244B2 (https=) |
| CA (1) | CA1311430C (https=) |
| DE (1) | DE3686646T2 (https=) |
| DK (1) | DK600486A (https=) |
| ES (1) | ES2046177T3 (https=) |
| GR (1) | GR3006178T3 (https=) |
| SE (1) | SE8505922D0 (https=) |
Families Citing this family (89)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK528285D0 (da) * | 1985-11-15 | 1985-11-15 | Novo Industri As | Peptider samt praeparater indeholdende disse |
| SE8505921D0 (sv) * | 1985-12-13 | 1985-12-13 | Kabigen Ab | A method to export gene products to the growth medium of gram negative bacteria |
| SE8601940D0 (sv) * | 1986-04-25 | 1986-04-25 | Kabigen Ab | Preparation of fused proteins, antibodies and processes therefor |
| US5985599A (en) * | 1986-05-29 | 1999-11-16 | The Austin Research Institute | FC receptor for immunoglobulin |
| ATE243754T1 (de) * | 1987-05-21 | 2003-07-15 | Micromet Ag | Multifunktionelle proteine mit vorbestimmter zielsetzung |
| ATE87007T1 (de) * | 1987-05-29 | 1993-04-15 | Sagami Chem Res | Fusionsprotein, enthaltend lymphotoxin. |
| DE3887750T2 (de) * | 1987-11-20 | 1994-09-15 | Creative Biomolecules Inc | Selektive entfernung von immunkomplexen. |
| US5084398A (en) * | 1987-11-20 | 1992-01-28 | Creative Biomolecules | Selective removal of immune complexes |
| US5243040A (en) * | 1987-11-20 | 1993-09-07 | Creative Biomolecules | DNA encoding a protein which enables selective removal of immune complexes |
| SE8800981D0 (sv) * | 1988-03-17 | 1988-03-17 | Nygren Per Ake | A recombinant fusion protein, its use and a recombinant vector |
| SE509359C2 (sv) * | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| GB8927008D0 (en) * | 1989-11-29 | 1990-01-17 | Ciba Geigy | Novel process for the production of unfused protein in e.coli |
| US5681814A (en) * | 1990-06-07 | 1997-10-28 | Genentech, Inc. | Formulated IGF-I Composition |
| US5595887A (en) * | 1990-07-16 | 1997-01-21 | Bionebraska, Inc. | Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment |
| US6077694A (en) * | 1990-09-21 | 2000-06-20 | The United States Of America As Represented By The Department Of Health And Human Services | Method for over-expression and rapid purification of biosynthetic proteins |
| US5863783A (en) * | 1991-03-27 | 1999-01-26 | Gist-Brocades, N.V. | Cloning and expression of DNA molecules encoding arabinan-degrading enzymes of fungal origin |
| AU2368892A (en) * | 1991-07-29 | 1993-03-02 | British Bio-Technology Limited | Igf-ii analogues |
| US5989887A (en) * | 1992-11-25 | 1999-11-23 | Dsm N.V. | Cloning and expression of DNA molecules incoding arabinan-degrading enzymes of fungal origin |
| SE9504019D0 (sv) * | 1995-11-13 | 1995-11-13 | Pharmacia Ab | Method for production of proteins |
| US5917026A (en) * | 1996-02-05 | 1999-06-29 | Loewenadler; Bjoern | Fusion proteins of immunopotentiating activity |
| US5962270A (en) | 1996-02-06 | 1999-10-05 | Bionebraska, Inc. | Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs |
| WO1998011913A1 (en) * | 1996-09-16 | 1998-03-26 | Dalhousie University | Use of igf-i for the treatment of polycystic kidney disease and related indications |
| US6593290B1 (en) | 1996-11-01 | 2003-07-15 | Genentech, Inc. | Treatment of inner ear hair cells |
| US6156728A (en) | 1996-11-01 | 2000-12-05 | Genentech, Inc. | Treatment of inner ear hair cells |
| US6121416A (en) | 1997-04-04 | 2000-09-19 | Genentech, Inc. | Insulin-like growth factor agonist molecules |
| US6420518B1 (en) | 1997-04-04 | 2002-07-16 | Genetech, Inc. | Insulin-like growth factor agonist molecules |
| AU762351B2 (en) | 1999-01-06 | 2003-06-26 | Genentech Inc. | Insulin-like growth factor (IGF) I mutant variants |
| JP2002535967A (ja) | 1999-01-06 | 2002-10-29 | ジェネンテック・インコーポレーテッド | インシュリン様成長因子(igf)i変異体 |
| AU763039B2 (en) | 1999-04-08 | 2003-07-10 | Genentech Inc. | Composition based on oppositely-charged polypeptides |
| ATE389416T1 (de) | 2000-05-16 | 2008-04-15 | Genentech Inc | Behandlung von knorpelerkrankungen |
| US20030157561A1 (en) * | 2001-11-19 | 2003-08-21 | Kolkman Joost A. | Combinatorial libraries of monomer domains |
| SE0200943D0 (sv) | 2002-03-25 | 2002-03-25 | Amersham Biosciences Ab | Mutant protein |
| US20050003548A1 (en) * | 2002-07-22 | 2005-01-06 | Nikolay Korokhov | Targeted adenoviral vector displaying immunoglobulin-binding domain and uses thereof |
| EP2274978B1 (en) | 2003-09-12 | 2015-05-20 | Tercica, Inc. | Methods for treatment of insulin-like growth factor-I(IGF-I) deficiency |
| US7192738B2 (en) | 2003-10-03 | 2007-03-20 | Genentech, Inc. | IGF binding proteins |
| JP5634008B2 (ja) | 2004-04-06 | 2014-12-03 | アフィボディ・アーベー | 新規の使用および方法 |
| ES2577292T3 (es) | 2005-11-07 | 2016-07-14 | Genentech, Inc. | Polipéptidos de unión con secuencias hipervariables de VH/VL diversificadas y consenso |
| CA2631327C (en) | 2005-12-02 | 2015-10-13 | Genentech, Inc. | Her2 binding polypeptides and uses thereof |
| JP2008048607A (ja) | 2006-08-22 | 2008-03-06 | Chisso Corp | Fc結合ドメインとカルシウム結合発光蛋白質との融合蛋白質、それをコードする遺伝子およびそれらの用途 |
| GB2442118B (en) * | 2006-09-19 | 2011-08-17 | Chisso Corp | Process for production of recombinant proteins as a soluble form |
| EP2099932A4 (en) | 2006-12-06 | 2009-11-18 | Repligen Corp | NUCLEIC ACIDS ENCODING THE RECOMBINANT PROTEIN A |
| US8198043B2 (en) * | 2006-12-08 | 2012-06-12 | General Electric Company | Two helix binders |
| US8592555B2 (en) | 2008-08-11 | 2013-11-26 | Emd Millipore Corporation | Immunoglobulin-binding proteins with improved specificity |
| SG195555A1 (en) | 2008-12-24 | 2013-12-30 | Emd Millipore Corp | Caustic stable chromatography ligands |
| JPWO2010110288A1 (ja) | 2009-03-24 | 2012-09-27 | 株式会社カネカ | 免疫グロブリンに親和性を有するタンパク質および免疫グロブリン結合性アフィニティーリガンド |
| CA2756244A1 (en) | 2009-04-02 | 2010-10-07 | Roche Glycart Ag | Multispecific antibodies comprising full length antibodies and single chain fab fragments |
| EP2478013B1 (en) | 2009-09-16 | 2018-10-24 | F.Hoffmann-La Roche Ag | Coiled coil and/or tether containing protein complexes and uses thereof |
| CA2789738C (en) * | 2010-03-08 | 2021-03-09 | Ge Healthcare Bio-Sciences Ab | Immunoglobulin g fc region binding polypeptide |
| WO2011118699A1 (ja) | 2010-03-24 | 2011-09-29 | 株式会社カネカ | 免疫グロブリンに特異的に結合するタンパク質および免疫グロブリン結合性アフィニティーリガンド |
| TW201138821A (en) | 2010-03-26 | 2011-11-16 | Roche Glycart Ag | Bispecific antibodies |
| KR101860963B1 (ko) | 2010-04-23 | 2018-05-24 | 제넨테크, 인크. | 이종다량체 단백질의 생산 |
| CA2808185A1 (en) | 2010-08-13 | 2012-02-16 | Genentech, Inc. | Antibodies to il-1.beta. and il-18, for treatment of disease |
| CN103068846B9 (zh) | 2010-08-24 | 2016-09-28 | 弗·哈夫曼-拉罗切有限公司 | 包含二硫键稳定性Fv片段的双特异性抗体 |
| CN103269762B (zh) | 2010-12-20 | 2016-01-27 | 通用电气健康护理生物科学股份公司 | 亲和色谱基质 |
| JP5974342B2 (ja) | 2010-12-20 | 2016-08-23 | ジーイー・ヘルスケア・バイオプロセス・アールアンドディ・アクチボラグ | アフィニティークロマトグラフィーマトリックス |
| SG191153A1 (en) | 2010-12-23 | 2013-07-31 | Hoffmann La Roche | Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery |
| RU2018108836A (ru) | 2011-02-04 | 2019-03-14 | Дженентек, Инк. | ВАРИАНТЫ Fc И СПОСОБЫ ИХ ПОЛУЧЕНИЯ |
| US10689447B2 (en) | 2011-02-04 | 2020-06-23 | Genentech, Inc. | Fc variants and methods for their production |
| EP2690108B1 (en) | 2011-03-25 | 2018-07-25 | Kaneka Corporation | Novel immunoglobulin-binding polypeptide |
| SG186552A1 (en) | 2011-06-08 | 2013-01-30 | Emd Millipore Corp | Chromatography matrices including novel staphylococcus aureus protein a based ligands |
| RU2654567C2 (ru) | 2011-10-11 | 2018-05-21 | Дженентек, Инк. | Улучшенная сборка биспецифических антител |
| CA2861124A1 (en) | 2012-02-10 | 2013-08-15 | Genentech, Inc. | Single-chain antibodies and other heteromultimers |
| EP2831096B1 (en) | 2012-03-28 | 2020-04-29 | GE Healthcare BioProcess R&D AB | Affinity chromatography matrix |
| RU2639287C2 (ru) | 2012-06-27 | 2017-12-20 | Ф. Хоффманн-Ля Рош Аг | Способ отбора и получения высокоселективных и мультиспецифичных нацеливающих групп с заданными свойствами, включающих по меньшей мере две различные связывающие группировки, и их применения |
| KR20150030744A (ko) | 2012-06-27 | 2015-03-20 | 에프. 호프만-라 로슈 아게 | 표적에 특이적으로 결합하는 하나 이상의 결합 단위를 포함하는 항체 Fc-영역 접합체의 제조 방법 및 그의 용도 |
| EP3019520B1 (en) | 2013-07-10 | 2019-12-11 | GE Healthcare BioProcess R&D AB | Mutated immunoglobulin-binding polypeptides |
| US10221211B2 (en) | 2013-09-27 | 2019-03-05 | Kaneka Corporation | Process for producing porous cellulose beads using alkali aqueous solution |
| BR122021009041B1 (pt) | 2014-05-06 | 2022-11-29 | Genentech, Inc | Métodos para a preparação de uma proteína heteromultimérica |
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| EP3227332B1 (en) | 2014-12-03 | 2019-11-06 | F.Hoffmann-La Roche Ag | Multispecific antibodies |
| CN108064286A (zh) | 2015-01-26 | 2018-05-22 | 株式会社钟化 | 突变型免疫球蛋白κ链可变区结合性肽 |
| WO2016121701A1 (ja) | 2015-01-26 | 2016-08-04 | 株式会社カネカ | 免疫グロブリンκ鎖可変領域含有タンパク質精製用アフィニティー分離マトリックス |
| JP6424101B2 (ja) * | 2015-01-30 | 2018-11-14 | Jnc株式会社 | Fc結合ドメインとカルシウム結合発光蛋白質との融合蛋白質、それをコードする遺伝子およびそれらの用途 |
| CN107428807A (zh) | 2015-02-05 | 2017-12-01 | 三菱化学株式会社 | 对免疫球蛋白具有亲和性的蛋白质和使用它的亲和分离剂、液相色谱柱 |
| WO2017195638A1 (ja) | 2016-05-09 | 2017-11-16 | 株式会社カネカ | 抗体またはκ鎖可変領域含有抗体断片の精製方法 |
| WO2017194592A1 (en) | 2016-05-11 | 2017-11-16 | Ge Healthcare Bioprocess R&D Ab | Method of storing a separation matrix |
| JP7031934B2 (ja) | 2016-05-11 | 2022-03-08 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックス |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10513537B2 (en) | 2016-05-11 | 2019-12-24 | Ge Healthcare Bioprocess R&D Ab | Separation matrix |
| WO2017194593A1 (en) | 2016-05-11 | 2017-11-16 | Ge Healthcare Bioprocess R&D Ab | Method of cleaning and/or sanitizing a separation matrix |
| US12448411B2 (en) | 2016-09-30 | 2025-10-21 | Cytiva Bioprocess R&D Ab | Separation method |
| US11779860B2 (en) | 2017-08-07 | 2023-10-10 | Repligen Corporation | Fc binding proteins with cysteine in the C-terminal helical region |
| EP3521304B9 (en) | 2018-02-01 | 2023-10-04 | Repligen Corporation | Fc binding proteins with cysteine in the c-terminal helical region |
| GB202018588D0 (en) | 2020-11-26 | 2021-01-13 | Cytiva Bioprocess R & D Ab | Separation matrix |
| GB202113626D0 (en) | 2021-09-24 | 2021-11-10 | Cytiva Bioprocess R & D Ab | FC binding polypeptides |
| WO2026057420A1 (en) | 2024-09-10 | 2026-03-19 | Cytiva Bioprocess R&D Ab | Affinity ligand for purification of antibodies of isotype iga |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4769326A (en) * | 1980-02-29 | 1988-09-06 | The Regents Of The University Of California | Expression linkers |
| SE8300693L (sv) * | 1983-02-09 | 1984-08-10 | Sven Lofdahl | Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta |
-
1985
- 1985-12-13 SE SE8505922A patent/SE8505922D0/xx unknown
-
1986
- 1986-12-02 EP EP86850416A patent/EP0230869B1/en not_active Expired
- 1986-12-02 ES ES198686850416T patent/ES2046177T3/es not_active Expired - Lifetime
- 1986-12-02 DE DE8686850416T patent/DE3686646T2/de not_active Expired - Fee Related
- 1986-12-02 AT AT86850416T patent/ATE80180T1/de not_active IP Right Cessation
- 1986-12-09 AU AU66331/86A patent/AU600244B2/en not_active Ceased
- 1986-12-12 DK DK600486A patent/DK600486A/da not_active Application Discontinuation
- 1986-12-12 JP JP61296509A patent/JPH0811069B2/ja not_active Expired - Lifetime
- 1986-12-12 CA CA000525167A patent/CA1311430C/en not_active Expired - Fee Related
-
1990
- 1990-10-09 US US07/594,564 patent/US5143844A/en not_active Expired - Lifetime
-
1992
- 1992-11-05 GR GR920402499T patent/GR3006178T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0230869B1 (en) | 1992-09-02 |
| ES2046177T3 (es) | 1994-02-01 |
| DK600486D0 (da) | 1986-12-12 |
| CA1311430C (en) | 1992-12-15 |
| AU6633186A (en) | 1987-06-18 |
| EP0230869A3 (en) | 1988-08-03 |
| DE3686646D1 (de) | 1992-10-08 |
| DK600486A (da) | 1987-06-14 |
| JPH0811069B2 (ja) | 1996-02-07 |
| GR3006178T3 (https=) | 1993-06-21 |
| AU600244B2 (en) | 1990-08-09 |
| DE3686646T2 (de) | 1993-04-08 |
| US5143844A (en) | 1992-09-01 |
| EP0230869A2 (en) | 1987-08-05 |
| ATE80180T1 (de) | 1992-09-15 |
| JPS62190087A (ja) | 1987-08-20 |
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