ATE389416T1 - Behandlung von knorpelerkrankungen - Google Patents
Behandlung von knorpelerkrankungenInfo
- Publication number
- ATE389416T1 ATE389416T1 AT01937482T AT01937482T ATE389416T1 AT E389416 T1 ATE389416 T1 AT E389416T1 AT 01937482 T AT01937482 T AT 01937482T AT 01937482 T AT01937482 T AT 01937482T AT E389416 T1 ATE389416 T1 AT E389416T1
- Authority
- AT
- Austria
- Prior art keywords
- igf
- treatment
- cartilage
- cartilary
- diseases
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title 1
- 102000028416 insulin-like growth factor binding Human genes 0.000 abstract 4
- 108091022911 insulin-like growth factor binding Proteins 0.000 abstract 4
- 102100037852 Insulin-like growth factor I Human genes 0.000 abstract 2
- 210000000845 cartilage Anatomy 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010061762 Chondropathy Diseases 0.000 abstract 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 1
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 208000015100 cartilage disease Diseases 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 208000014674 injury Diseases 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4743—Insulin-like growth factor binding protein
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Marine Sciences & Fisheries (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20449000P | 2000-05-16 | 2000-05-16 | |
US24898500P | 2000-11-15 | 2000-11-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE389416T1 true ATE389416T1 (de) | 2008-04-15 |
Family
ID=26899527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01937482T ATE389416T1 (de) | 2000-05-16 | 2001-05-16 | Behandlung von knorpelerkrankungen |
Country Status (9)
Country | Link |
---|---|
US (4) | US20030069177A1 (de) |
EP (1) | EP1282437B1 (de) |
AT (1) | ATE389416T1 (de) |
AU (1) | AU2001263215A1 (de) |
DE (1) | DE60133271T2 (de) |
DK (1) | DK1282437T3 (de) |
ES (1) | ES2301547T3 (de) |
HK (1) | HK1050321A1 (de) |
WO (1) | WO2001087323A2 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1099443A1 (de) | 1999-11-11 | 2001-05-16 | Sulzer Orthopedics Ltd. | Transplantations/Implantatsvorrichtung und ihre Herstellungsmethode |
US7387889B2 (en) * | 2002-08-22 | 2008-06-17 | Massachusetts Institute Of Technology | Measurement of concentrations and binding energetics |
US8173162B2 (en) * | 2003-02-26 | 2012-05-08 | Zimmer Orthobiologics, Inc. | Preparation for repairing cartilage tissue, especially articular cartilage defects |
EP1740190A1 (de) * | 2004-03-05 | 2007-01-10 | Synthes GmbH | Verwendung eines gemisches für die herstellung eines mittels zur behandlung von defektem oder degeneriertem knorpel in vivo und bei der herstellung von natürlichem knorpelersatz in vitro |
WO2005122723A2 (en) * | 2004-06-09 | 2005-12-29 | Beth Israel Deaconess Medical Center | Compositions and methods that enhance articular cartilage repair |
EP1764117A1 (de) | 2005-09-20 | 2007-03-21 | Zimmer GmbH | Implantat zur Wiederherstellung von Knorpeldefekten und Verfahren zu seiner Herstellung |
AU2007212085B2 (en) | 2006-02-07 | 2011-11-17 | Spinalcyte, Llc | Methods and compositions for repair of cartilage using an in vivo bioreactor |
CL2007002502A1 (es) * | 2006-08-31 | 2008-05-30 | Hoffmann La Roche | Variantes del factor de crecimiento similar a insulina-1 humano (igf-1) pegilados en lisina; metodo de produccion; proteina de fusion que la comprende; y su uso para tratar la enfermedad de alzheimer. |
GEP20125659B (en) * | 2006-12-29 | 2012-10-10 | Ipsen Pharma Sas | Pharmaceutical compositions containing glucagon-like peptide-1 (glp-1) |
BRPI0920030B1 (pt) | 2008-10-06 | 2019-03-26 | 3-D Matrix, Ltd. | Agente de oclusão do tecido, agentes hemostáticos, preventivos e de oclusão ou escleroterapia relacionados, e infusão do tecido mucosal |
JP5739816B2 (ja) | 2008-12-19 | 2015-06-24 | バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated | Tfpiインヒビターおよび使用法 |
WO2011115712A2 (en) | 2010-03-19 | 2011-09-22 | Baxter International Inc | Tfpi inhibitors and methods of use |
US20140314726A1 (en) * | 2011-11-09 | 2014-10-23 | Spinalcyte, Llc | Fibroblasts for treatment of degenerative disc disease |
WO2013141965A1 (en) | 2012-03-21 | 2013-09-26 | Baxter International Inc. | Tfpi inhibitors and methods of use |
US9637531B2 (en) * | 2012-06-25 | 2017-05-02 | The Brigham And Women's Hospital, Inc | Selective cartilage therapy |
EP2869903B1 (de) | 2012-07-06 | 2018-11-28 | 3-D Matrix Ltd. | Füllabschlussverfahren für peptidlösungen |
ES2870558T3 (es) | 2013-06-19 | 2021-10-27 | Spinalcyte Llc | Adipocitos para aplicaciones de condrocitos |
CN106459154A (zh) | 2014-03-10 | 2017-02-22 | 三维矩阵有限责任公司 | 自组装肽组合物 |
EP3116524B1 (de) | 2014-03-10 | 2018-11-28 | 3-D Matrix Ltd. | Peptides autoassémblants pour le traitement de la bulle pulmonaire |
JP6684719B2 (ja) | 2014-03-10 | 2020-04-22 | 株式会社スリー・ディー・マトリックス | ペプチド組成物の滅菌および濾過 |
US10814038B2 (en) | 2016-01-06 | 2020-10-27 | 3-D Matrix, Ltd. | Combination compositions |
US11324703B2 (en) | 2017-12-15 | 2022-05-10 | 3-D Matrix, Ltd. | Surfactant peptide nanostructures and uses thereof in drug delivery |
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-
2001
- 2001-05-16 EP EP01937482A patent/EP1282437B1/de not_active Expired - Lifetime
- 2001-05-16 US US09/858,935 patent/US20030069177A1/en not_active Abandoned
- 2001-05-16 DE DE60133271T patent/DE60133271T2/de not_active Expired - Lifetime
- 2001-05-16 DK DK01937482T patent/DK1282437T3/da active
- 2001-05-16 AU AU2001263215A patent/AU2001263215A1/en not_active Abandoned
- 2001-05-16 WO PCT/US2001/015904 patent/WO2001087323A2/en active Application Filing
- 2001-05-16 AT AT01937482T patent/ATE389416T1/de active
- 2001-05-16 ES ES01937482T patent/ES2301547T3/es not_active Expired - Lifetime
-
2002
- 2002-10-16 US US10/271,869 patent/US7423017B2/en not_active Expired - Fee Related
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2003
- 2003-04-04 HK HK03102436A patent/HK1050321A1/xx not_active IP Right Cessation
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2007
- 2007-10-30 US US11/929,468 patent/US7947650B2/en not_active Expired - Fee Related
- 2007-11-02 US US11/934,582 patent/US8110548B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20030211992A1 (en) | 2003-11-13 |
HK1050321A1 (en) | 2003-06-20 |
AU2001263215A1 (en) | 2001-11-26 |
DE60133271D1 (de) | 2008-04-30 |
US20090011988A1 (en) | 2009-01-08 |
EP1282437A2 (de) | 2003-02-12 |
ES2301547T3 (es) | 2008-07-01 |
WO2001087323A2 (en) | 2001-11-22 |
DK1282437T3 (da) | 2008-06-30 |
US8110548B2 (en) | 2012-02-07 |
EP1282437B1 (de) | 2008-03-19 |
WO2001087323A3 (en) | 2002-04-11 |
US7423017B2 (en) | 2008-09-09 |
US20100130411A1 (en) | 2010-05-27 |
US20030069177A1 (en) | 2003-04-10 |
DE60133271T2 (de) | 2009-04-23 |
US7947650B2 (en) | 2011-05-24 |
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