SE8304887L - Forfarande for uppspjelkning av en racemisk modifikation av beta-adrenergiska aryl- eller hetaryloxipropanolaminer - Google Patents
Forfarande for uppspjelkning av en racemisk modifikation av beta-adrenergiska aryl- eller hetaryloxipropanolaminerInfo
- Publication number
- SE8304887L SE8304887L SE8304887A SE8304887A SE8304887L SE 8304887 L SE8304887 L SE 8304887L SE 8304887 A SE8304887 A SE 8304887A SE 8304887 A SE8304887 A SE 8304887A SE 8304887 L SE8304887 L SE 8304887L
- Authority
- SE
- Sweden
- Prior art keywords
- racemic modification
- beta
- aryl
- hetaryloxypropanolamines
- addrenergic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/417,794 US4463176A (en) | 1982-09-13 | 1982-09-13 | Process for resolution of optical isomers |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8304887D0 SE8304887D0 (sv) | 1983-09-12 |
SE8304887L true SE8304887L (sv) | 1984-03-14 |
SE452608B SE452608B (sv) | 1987-12-07 |
Family
ID=23655420
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8304887A SE452608B (sv) | 1982-09-13 | 1983-09-12 | Forfarande for uppspjelkning av en racemisk modifikation av beta-adrenergiska aryl- eller hetaryloxipropanolaminer |
SE8602724A SE8602724D0 (sv) | 1982-09-13 | 1986-06-18 | Karbamidmellanprodukter och forfarande for framstellning derav |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8602724A SE8602724D0 (sv) | 1982-09-13 | 1986-06-18 | Karbamidmellanprodukter och forfarande for framstellning derav |
Country Status (29)
Country | Link |
---|---|
US (1) | US4463176A (sv) |
JP (2) | JPS5980616A (sv) |
KR (1) | KR890000616B1 (sv) |
AT (1) | AT385032B (sv) |
AU (1) | AU573535B2 (sv) |
BE (1) | BE897737A (sv) |
CA (1) | CA1250290A (sv) |
CH (1) | CH660732A5 (sv) |
CY (1) | CY1543A (sv) |
DE (1) | DE3333025A1 (sv) |
DK (2) | DK172720B1 (sv) |
ES (1) | ES525543A0 (sv) |
FI (1) | FI83767C (sv) |
FR (1) | FR2540490B1 (sv) |
GB (2) | GB2127020B (sv) |
GR (1) | GR81546B (sv) |
HK (1) | HK97990A (sv) |
HU (1) | HU193183B (sv) |
IE (1) | IE55650B1 (sv) |
IL (1) | IL69708A (sv) |
IT (1) | IT1170213B (sv) |
LU (1) | LU84998A1 (sv) |
NL (1) | NL8303154A (sv) |
NO (1) | NO159267C (sv) |
NZ (1) | NZ205554A (sv) |
PT (1) | PT77331B (sv) |
SE (2) | SE452608B (sv) |
YU (1) | YU43327B (sv) |
ZA (1) | ZA836795B (sv) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4849527A (en) * | 1982-09-13 | 1989-07-18 | Bristol-Myers Company | Process for resolution of optical isomers |
IT1163107B (it) * | 1983-02-15 | 1987-04-08 | Simes | Composizioni farmaceutiche e loro uso nel trattamento del glaucoma |
US5364872A (en) * | 1984-04-16 | 1994-11-15 | Yamanouchi Pharmaceutical Co., Ltd. | Dihydropyridine-3,5-dicarboxylic acid ester derivatives |
US5039801A (en) * | 1985-12-20 | 1991-08-13 | The United States Of America As Represented By The Department Of Health & Human Services | Thermal fragmentation of methylbenzylurea disastereomers or secondary amines and preparation of optically active secondary amines |
US4797498A (en) * | 1986-07-18 | 1989-01-10 | Pennwalt Corporation | Flavonoxypropanolamines and esters of flavonoxypropanolamines as antiarrhythmic agents |
WO1988007044A1 (en) * | 1987-03-17 | 1988-09-22 | Insite Vision, Inc. | Timolol derivatives |
US4889941A (en) * | 1987-04-23 | 1989-12-26 | Fisons Corporation | Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxygenase |
US4806660A (en) * | 1987-11-06 | 1989-02-21 | Pennwalt Corporation | Aurone oxypropanolamines |
JP2801768B2 (ja) * | 1990-11-17 | 1998-09-21 | 日東電工株式会社 | 新規な光学活性メトプロロール・酒石酸誘導体塩及びその製法、並びにこの塩を用いる光学活性メトプロロールの製法 |
US5082970A (en) * | 1991-03-06 | 1992-01-21 | Pfizer Inc. | Process for recycling amine isomer |
ES2065278B1 (es) * | 1993-06-24 | 1995-09-01 | Medichem Sa | Procedimiento de obtencion enantioselectivo del levobunolol. |
AU702594B2 (en) * | 1995-10-13 | 1999-02-25 | Duphar International Research B.V. | Process for the preparation of enantiomerically pure imidazolyl compounds |
KR100332399B1 (ko) * | 1999-02-22 | 2002-04-13 | 김경호 | 메토프롤롤 라세미체로부터 메토프롤롤 에난티오머의 제조방법 |
BE1012622A3 (fr) | 1999-04-21 | 2001-01-09 | Solvay | Procede pour la separation d'enantiomeres et reactif enantiopur. |
US7138538B2 (en) * | 2000-04-14 | 2006-11-21 | Solvay (Societe Anonyme) | Process for the separation of enantiomers and enantiopure reagent |
CA2495962A1 (en) | 2002-08-19 | 2004-03-04 | Pfizer Products Inc. | Combination therapy for hyperproliferative diseases |
US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
CN101663262B (zh) | 2006-12-01 | 2014-03-26 | 百时美施贵宝公司 | 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物 |
WO2008112287A1 (en) | 2007-03-12 | 2008-09-18 | Nektar Therapeutics | Oligomer-beta blocker conjugates |
KR101695582B1 (ko) | 2013-04-17 | 2017-01-13 | 화이자 인코포레이티드 | 심혈관 질환을 치료하기 위한 n-피페리딘-3-일벤즈아미드 유도체 |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
JOP20210193A1 (ar) | 2019-01-18 | 2023-01-30 | Astrazeneca Ab | مثبطات pcsk9 وطرق استخدامها |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US234595A (en) * | 1880-11-16 | Juan f | ||
GB1211589A (en) * | 1968-08-06 | 1970-11-11 | Ici Ltd | Enantiomer isolation process |
BE786963A (fr) * | 1971-07-30 | 1973-01-29 | Degussa | Procede pour le dedoublement racemique de d,1-phenylpropanolamine |
US4234595A (en) * | 1977-07-13 | 1980-11-18 | Mead Johnson & Company | 3-Indolyl-tertiary butylaminopropanols |
US4314943A (en) * | 1977-07-13 | 1982-02-09 | Mead Johnson & Company | Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols |
IT1113029B (it) * | 1979-03-01 | 1986-01-20 | Simes | Processo per la separazione dei due isomeri ottici del moprololo e composizioni farmaceutiche dell'antipodo levogiro |
JPS5770884A (en) * | 1980-10-21 | 1982-05-01 | Kyowa Hakko Kogyo Co Ltd | Novel piperidine derivative and its preparation |
FI76551C (sv) * | 1980-11-06 | 1988-11-10 | Sandoz Ag | Förfarande för framställning av nya terapeutiskt användbara 3-aminopro poxifenylderivat |
-
1982
- 1982-09-13 US US06/417,794 patent/US4463176A/en not_active Expired - Lifetime
-
1983
- 1983-09-12 BE BE0/211517A patent/BE897737A/fr not_active IP Right Cessation
- 1983-09-12 NO NO833254A patent/NO159267C/no not_active IP Right Cessation
- 1983-09-12 LU LU84998A patent/LU84998A1/fr unknown
- 1983-09-12 FR FR8314464A patent/FR2540490B1/fr not_active Expired
- 1983-09-12 GR GR72427A patent/GR81546B/el unknown
- 1983-09-12 IT IT22852/83A patent/IT1170213B/it active
- 1983-09-12 IE IE2134/83A patent/IE55650B1/en not_active IP Right Cessation
- 1983-09-12 SE SE8304887A patent/SE452608B/sv not_active IP Right Cessation
- 1983-09-12 ES ES525543A patent/ES525543A0/es active Granted
- 1983-09-12 NZ NZ205554A patent/NZ205554A/en unknown
- 1983-09-12 PT PT77331A patent/PT77331B/pt unknown
- 1983-09-12 CA CA000436530A patent/CA1250290A/en not_active Expired
- 1983-09-12 CH CH4958/83A patent/CH660732A5/fr not_active IP Right Cessation
- 1983-09-13 GB GB08324536A patent/GB2127020B/en not_active Expired
- 1983-09-13 HU HU833181A patent/HU193183B/hu unknown
- 1983-09-13 AT AT0326383A patent/AT385032B/de not_active IP Right Cessation
- 1983-09-13 AU AU19081/83A patent/AU573535B2/en not_active Expired
- 1983-09-13 KR KR1019830004298A patent/KR890000616B1/ko not_active IP Right Cessation
- 1983-09-13 NL NL8303154A patent/NL8303154A/nl active Search and Examination
- 1983-09-13 DK DK198304164A patent/DK172720B1/da not_active IP Right Cessation
- 1983-09-13 DE DE19833333025 patent/DE3333025A1/de active Granted
- 1983-09-13 YU YU1846/83A patent/YU43327B/xx unknown
- 1983-09-13 JP JP58167667A patent/JPS5980616A/ja active Granted
- 1983-09-13 ZA ZA836795A patent/ZA836795B/xx unknown
- 1983-09-13 IL IL69708A patent/IL69708A/xx not_active IP Right Cessation
- 1983-10-13 FI FI833270A patent/FI83767C/sv not_active IP Right Cessation
-
1986
- 1986-02-24 GB GB08604515A patent/GB2169294B/en not_active Expired
- 1986-06-18 SE SE8602724A patent/SE8602724D0/sv not_active Application Discontinuation
-
1990
- 1990-11-22 HK HK979/90A patent/HK97990A/xx not_active IP Right Cessation
-
1991
- 1991-03-22 CY CY1543A patent/CY1543A/xx unknown
- 1991-09-25 JP JP3315620A patent/JP2759184B2/ja not_active Expired - Lifetime
-
1997
- 1997-09-17 DK DK199701068A patent/DK172732B1/da not_active IP Right Cessation
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Legal Events
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NAL | Patent in force |
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