NO833254L - Fremgangsmaate til oppspaltning av optiske isomere - Google Patents

Fremgangsmaate til oppspaltning av optiske isomere

Info

Publication number
NO833254L
NO833254L NO833254A NO833254A NO833254L NO 833254 L NO833254 L NO 833254L NO 833254 A NO833254 A NO 833254A NO 833254 A NO833254 A NO 833254A NO 833254 L NO833254 L NO 833254L
Authority
NO
Norway
Prior art keywords
procedure
distribution
optical isomers
isomers
optical
Prior art date
Application number
NO833254A
Other languages
English (en)
Other versions
NO159267C (no
NO159267B (no
Inventor
Ronald D Dennis
Terence M Dolak
William E Kreighbaum
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of NO833254L publication Critical patent/NO833254L/no
Priority to NO88881179A priority Critical patent/NO168638C/no
Publication of NO159267B publication Critical patent/NO159267B/no
Publication of NO159267C publication Critical patent/NO159267C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO833254A 1982-09-13 1983-09-12 Fremgangsmaate for spalting av en racemisk modifikasjon avbeta-adrenerge aryl- eller hetaryloksypropanolaminer. NO159267C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO88881179A NO168638C (no) 1982-09-13 1988-03-17 Urinstoffderivater

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/417,794 US4463176A (en) 1982-09-13 1982-09-13 Process for resolution of optical isomers

Publications (3)

Publication Number Publication Date
NO833254L true NO833254L (no) 1984-03-14
NO159267B NO159267B (no) 1988-09-05
NO159267C NO159267C (no) 1988-12-14

Family

ID=23655420

Family Applications (1)

Application Number Title Priority Date Filing Date
NO833254A NO159267C (no) 1982-09-13 1983-09-12 Fremgangsmaate for spalting av en racemisk modifikasjon avbeta-adrenerge aryl- eller hetaryloksypropanolaminer.

Country Status (29)

Country Link
US (1) US4463176A (no)
JP (2) JPS5980616A (no)
KR (1) KR890000616B1 (no)
AT (1) AT385032B (no)
AU (1) AU573535B2 (no)
BE (1) BE897737A (no)
CA (1) CA1250290A (no)
CH (1) CH660732A5 (no)
CY (1) CY1543A (no)
DE (1) DE3333025A1 (no)
DK (2) DK172720B1 (no)
ES (1) ES8504104A1 (no)
FI (1) FI83767C (no)
FR (1) FR2540490B1 (no)
GB (2) GB2127020B (no)
GR (1) GR81546B (no)
HK (1) HK97990A (no)
HU (1) HU193183B (no)
IE (1) IE55650B1 (no)
IL (1) IL69708A (no)
IT (1) IT1170213B (no)
LU (1) LU84998A1 (no)
NL (1) NL8303154A (no)
NO (1) NO159267C (no)
NZ (1) NZ205554A (no)
PT (1) PT77331B (no)
SE (2) SE452608B (no)
YU (1) YU43327B (no)
ZA (1) ZA836795B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4849527A (en) * 1982-09-13 1989-07-18 Bristol-Myers Company Process for resolution of optical isomers
IT1163107B (it) * 1983-02-15 1987-04-08 Simes Composizioni farmaceutiche e loro uso nel trattamento del glaucoma
US5364872A (en) * 1984-04-16 1994-11-15 Yamanouchi Pharmaceutical Co., Ltd. Dihydropyridine-3,5-dicarboxylic acid ester derivatives
US5039801A (en) * 1985-12-20 1991-08-13 The United States Of America As Represented By The Department Of Health & Human Services Thermal fragmentation of methylbenzylurea disastereomers or secondary amines and preparation of optically active secondary amines
US4797498A (en) * 1986-07-18 1989-01-10 Pennwalt Corporation Flavonoxypropanolamines and esters of flavonoxypropanolamines as antiarrhythmic agents
EP0305496A4 (en) * 1987-03-17 1989-07-11 Insite Vision Inc TIMOLOL DERIVATIVES.
US4889941A (en) * 1987-04-23 1989-12-26 Fisons Corporation Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxygenase
US4806660A (en) * 1987-11-06 1989-02-21 Pennwalt Corporation Aurone oxypropanolamines
JP2801768B2 (ja) * 1990-11-17 1998-09-21 日東電工株式会社 新規な光学活性メトプロロール・酒石酸誘導体塩及びその製法、並びにこの塩を用いる光学活性メトプロロールの製法
US5082970A (en) * 1991-03-06 1992-01-21 Pfizer Inc. Process for recycling amine isomer
ES2065278B1 (es) * 1993-06-24 1995-09-01 Medichem Sa Procedimiento de obtencion enantioselectivo del levobunolol.
AU702594B2 (en) * 1995-10-13 1999-02-25 Duphar International Research B.V. Process for the preparation of enantiomerically pure imidazolyl compounds
KR100332399B1 (ko) * 1999-02-22 2002-04-13 김경호 메토프롤롤 라세미체로부터 메토프롤롤 에난티오머의 제조방법
BE1012622A3 (fr) * 1999-04-21 2001-01-09 Solvay Procede pour la separation d'enantiomeres et reactif enantiopur.
US7138538B2 (en) * 2000-04-14 2006-11-21 Solvay (Societe Anonyme) Process for the separation of enantiomers and enantiopure reagent
ATE502635T1 (de) 2002-08-19 2011-04-15 Pfizer Kombinationstherapie gegen hyperproliferative erkrankungen
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
US9782488B2 (en) 2007-03-12 2017-10-10 Nektar Therapeutics Oligomer-beta blocker conjugates
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのｎ−ピペリジン−３−イルベンズアミド誘導体
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
JP7128969B2 (ja) 2019-01-18 2022-08-31 アストラゼネカ・アクチエボラーグ Ｐｃｓｋ９阻害剤及びその使用方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US234595A (en) * 1880-11-16 Juan f
GB1211589A (en) * 1968-08-06 1970-11-11 Ici Ltd Enantiomer isolation process
BE786963A (fr) * 1971-07-30 1973-01-29 Degussa Procede pour le dedoublement racemique de d,1-phenylpropanolamine
US4314943A (en) * 1977-07-13 1982-02-09 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
US4234595A (en) * 1977-07-13 1980-11-18 Mead Johnson & Company 3-Indolyl-tertiary butylaminopropanols
IT1113029B (it) * 1979-03-01 1986-01-20 Simes Processo per la separazione dei due isomeri ottici del moprololo e composizioni farmaceutiche dell'antipodo levogiro
JPS5770884A (en) * 1980-10-21 1982-05-01 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative and its preparation
FI76551C (fi) * 1980-11-06 1988-11-10 Sandoz Ag Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-aminopropoxifenylderivat.

Also Published As

Publication number Publication date
HU193183B (en) 1987-08-28
SE8602724L (sv) 1986-06-18
PT77331B (en) 1986-08-28
ZA836795B (en) 1984-04-25
FI833270A0 (fi) 1983-09-13
JPS5980616A (ja) 1984-05-10
NZ205554A (en) 1987-09-30
NL8303154A (nl) 1984-04-02
CY1543A (en) 1991-03-22
CH660732A5 (fr) 1987-06-15
SE8304887L (sv) 1984-03-14
KR890000616B1 (ko) 1989-03-22
IE832134L (en) 1984-03-13
JP2759184B2 (ja) 1998-05-28
DK416483D0 (da) 1983-09-13
US4463176A (en) 1984-07-31
FR2540490A1 (fr) 1984-08-10
ATA326383A (de) 1987-07-15
LU84998A1 (fr) 1984-04-24
DK172732B1 (da) 1999-06-21
SE8602724D0 (sv) 1986-06-18
IE55650B1 (en) 1990-12-05
IL69708A (en) 1987-02-27
DK172720B1 (da) 1999-06-14
ES525543A0 (es) 1985-04-16
FR2540490B1 (fr) 1986-09-05
ES8504104A1 (es) 1985-04-16
JPH0859597A (ja) 1996-03-05
DE3333025A1 (de) 1984-03-29
FI833270A (fi) 1984-03-14
NO159267C (no) 1988-12-14
GB8604515D0 (en) 1986-04-03
GB2127020A (en) 1984-04-04
GB2169294B (en) 1987-05-13
HK97990A (en) 1990-11-30
AT385032B (de) 1988-02-10
IL69708A0 (en) 1983-12-30
SE452608B (sv) 1987-12-07
DE3333025C2 (no) 1992-01-23
GB2169294A (en) 1986-07-09
CA1250290A (en) 1989-02-21
GB2127020B (en) 1987-05-07
SE8304887D0 (sv) 1983-09-12
DK106897A (da) 1997-09-17
PT77331A (en) 1983-10-01
IT8322852A0 (it) 1983-09-12
DK416483A (da) 1984-03-14
FI83767C (fi) 1991-08-26
YU43327B (en) 1989-06-30
GR81546B (no) 1984-12-11
YU184683A (en) 1986-02-28
KR840005998A (ko) 1984-11-21
GB8324536D0 (en) 1983-10-12
BE897737A (fr) 1984-03-12
FI83767B (fi) 1991-05-15
JPH0414086B2 (no) 1992-03-11
NO159267B (no) 1988-09-05
IT1170213B (it) 1987-06-03
AU573535B2 (en) 1988-06-16
AU1908183A (en) 1984-03-22

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Legal Events

Date Code Title Description
MK1K Patent expired

Free format text: EXPIRED IN SEPTEMBER 2003