DK416483A - Fremgangsmaade til opspaltning af isomere - Google Patents
Fremgangsmaade til opspaltning af isomere Download PDFInfo
- Publication number
- DK416483A DK416483A DK416483A DK416483A DK416483A DK 416483 A DK416483 A DK 416483A DK 416483 A DK416483 A DK 416483A DK 416483 A DK416483 A DK 416483A DK 416483 A DK416483 A DK 416483A
- Authority
- DK
- Denmark
- Prior art keywords
- spliting
- isomers
- procedure
- spliting isomers
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/417,794 US4463176A (en) | 1982-09-13 | 1982-09-13 | Process for resolution of optical isomers |
| US41779482 | 1982-09-13 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK416483D0 DK416483D0 (da) | 1983-09-13 |
| DK416483A true DK416483A (da) | 1984-03-14 |
| DK172720B1 DK172720B1 (da) | 1999-06-14 |
Family
ID=23655420
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198304164A DK172720B1 (da) | 1982-09-13 | 1983-09-13 | Fremgangsmåde til opspaltning af en racemisk modifikation af beta-adrenerge aryl- eller heteroarylpropanolaminer i de tilsv |
| DK199701068A DK172732B1 (da) | 1982-09-13 | 1997-09-17 | Fremgangsmåde til fremstilling af urinstofderivater |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK199701068A DK172732B1 (da) | 1982-09-13 | 1997-09-17 | Fremgangsmåde til fremstilling af urinstofderivater |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US4463176A (da) |
| JP (2) | JPS5980616A (da) |
| KR (1) | KR890000616B1 (da) |
| AT (1) | AT385032B (da) |
| AU (1) | AU573535B2 (da) |
| BE (1) | BE897737A (da) |
| CA (1) | CA1250290A (da) |
| CH (1) | CH660732A5 (da) |
| CY (1) | CY1543A (da) |
| DE (1) | DE3333025A1 (da) |
| DK (2) | DK172720B1 (da) |
| ES (1) | ES8504104A1 (da) |
| FI (1) | FI83767C (da) |
| FR (1) | FR2540490B1 (da) |
| GB (2) | GB2127020B (da) |
| GR (1) | GR81546B (da) |
| HK (1) | HK97990A (da) |
| HU (1) | HU193183B (da) |
| IE (1) | IE55650B1 (da) |
| IL (1) | IL69708A (da) |
| IT (1) | IT1170213B (da) |
| LU (1) | LU84998A1 (da) |
| NL (1) | NL8303154A (da) |
| NO (1) | NO159267C (da) |
| NZ (1) | NZ205554A (da) |
| PT (1) | PT77331B (da) |
| SE (2) | SE452608B (da) |
| YU (1) | YU43327B (da) |
| ZA (1) | ZA836795B (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4849527A (en) * | 1982-09-13 | 1989-07-18 | Bristol-Myers Company | Process for resolution of optical isomers |
| IT1163107B (it) * | 1983-02-15 | 1987-04-08 | Simes | Composizioni farmaceutiche e loro uso nel trattamento del glaucoma |
| US5364872A (en) * | 1984-04-16 | 1994-11-15 | Yamanouchi Pharmaceutical Co., Ltd. | Dihydropyridine-3,5-dicarboxylic acid ester derivatives |
| US5039801A (en) * | 1985-12-20 | 1991-08-13 | The United States Of America As Represented By The Department Of Health & Human Services | Thermal fragmentation of methylbenzylurea disastereomers or secondary amines and preparation of optically active secondary amines |
| US4797498A (en) * | 1986-07-18 | 1989-01-10 | Pennwalt Corporation | Flavonoxypropanolamines and esters of flavonoxypropanolamines as antiarrhythmic agents |
| EP0305496A4 (en) * | 1987-03-17 | 1989-07-11 | Insite Vision Inc | TIMOLOL DERIVATIVES. |
| US4889941A (en) * | 1987-04-23 | 1989-12-26 | Fisons Corporation | Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxygenase |
| US4806660A (en) * | 1987-11-06 | 1989-02-21 | Pennwalt Corporation | Aurone oxypropanolamines |
| JP2801768B2 (ja) * | 1990-11-17 | 1998-09-21 | 日東電工株式会社 | 新規な光学活性メトプロロール・酒石酸誘導体塩及びその製法、並びにこの塩を用いる光学活性メトプロロールの製法 |
| US5082970A (en) * | 1991-03-06 | 1992-01-21 | Pfizer Inc. | Process for recycling amine isomer |
| ES2065278B1 (es) * | 1993-06-24 | 1995-09-01 | Medichem Sa | Procedimiento de obtencion enantioselectivo del levobunolol. |
| AU702594B2 (en) * | 1995-10-13 | 1999-02-25 | Duphar International Research B.V. | Process for the preparation of enantiomerically pure imidazolyl compounds |
| KR100332399B1 (ko) * | 1999-02-22 | 2002-04-13 | 김경호 | 메토프롤롤 라세미체로부터 메토프롤롤 에난티오머의 제조방법 |
| BE1012622A3 (fr) * | 1999-04-21 | 2001-01-09 | Solvay | Procede pour la separation d'enantiomeres et reactif enantiopur. |
| US7138538B2 (en) * | 2000-04-14 | 2006-11-21 | Solvay (Societe Anonyme) | Process for the separation of enantiomers and enantiopure reagent |
| ATE502635T1 (de) | 2002-08-19 | 2011-04-15 | Pfizer | Kombinationstherapie gegen hyperproliferative erkrankungen |
| US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| JP5498168B2 (ja) | 2006-12-01 | 2014-05-21 | ブリストル−マイヤーズ スクイブ カンパニー | アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体 |
| US9782488B2 (en) | 2007-03-12 | 2017-10-10 | Nektar Therapeutics | Oligomer-beta blocker conjugates |
| JP2016516804A (ja) | 2013-04-17 | 2016-06-09 | ファイザー・インク | 心血管疾患を治療するためのｎ−ピペリジン−３−イルベンズアミド誘導体 |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| JP7128969B2 (ja) | 2019-01-18 | 2022-08-31 | アストラゼネカ・アクチエボラーグ | Ｐｃｓｋ９阻害剤及びその使用方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US234595A (en) * | 1880-11-16 | Juan f | ||
| GB1211589A (en) * | 1968-08-06 | 1970-11-11 | Ici Ltd | Enantiomer isolation process |
| BE786963A (fr) * | 1971-07-30 | 1973-01-29 | Degussa | Procede pour le dedoublement racemique de d,1-phenylpropanolamine |
| US4314943A (en) * | 1977-07-13 | 1982-02-09 | Mead Johnson & Company | Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols |
| US4234595A (en) * | 1977-07-13 | 1980-11-18 | Mead Johnson & Company | 3-Indolyl-tertiary butylaminopropanols |
| IT1113029B (it) * | 1979-03-01 | 1986-01-20 | Simes | Processo per la separazione dei due isomeri ottici del moprololo e composizioni farmaceutiche dell'antipodo levogiro |
| JPS5770884A (en) * | 1980-10-21 | 1982-05-01 | Kyowa Hakko Kogyo Co Ltd | Novel piperidine derivative and its preparation |
| FI76551C (fi) * | 1980-11-06 | 1988-11-10 | Sandoz Ag | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-aminopropoxifenylderivat. |
-
1982
- 1982-09-13 US US06/417,794 patent/US4463176A/en not_active Expired - Lifetime
-
1983
- 1983-09-12 NZ NZ205554A patent/NZ205554A/en unknown
- 1983-09-12 GR GR72427A patent/GR81546B/el unknown
- 1983-09-12 BE BE0/211517A patent/BE897737A/fr not_active IP Right Cessation
- 1983-09-12 PT PT77331A patent/PT77331B/pt unknown
- 1983-09-12 FR FR8314464A patent/FR2540490B1/fr not_active Expired
- 1983-09-12 CA CA000436530A patent/CA1250290A/en not_active Expired
- 1983-09-12 NO NO833254A patent/NO159267C/no not_active IP Right Cessation
- 1983-09-12 IT IT22852/83A patent/IT1170213B/it active
- 1983-09-12 IE IE2134/83A patent/IE55650B1/en not_active IP Right Cessation
- 1983-09-12 CH CH4958/83A patent/CH660732A5/fr not_active IP Right Cessation
- 1983-09-12 SE SE8304887A patent/SE452608B/sv not_active IP Right Cessation
- 1983-09-12 LU LU84998A patent/LU84998A1/fr unknown
- 1983-09-12 ES ES525543A patent/ES8504104A1/es not_active Expired
- 1983-09-13 KR KR1019830004298A patent/KR890000616B1/ko not_active IP Right Cessation
- 1983-09-13 HU HU833181A patent/HU193183B/hu unknown
- 1983-09-13 GB GB08324536A patent/GB2127020B/en not_active Expired
- 1983-09-13 NL NL8303154A patent/NL8303154A/nl active Search and Examination
- 1983-09-13 ZA ZA836795A patent/ZA836795B/xx unknown
- 1983-09-13 DK DK198304164A patent/DK172720B1/da not_active IP Right Cessation
- 1983-09-13 DE DE19833333025 patent/DE3333025A1/de active Granted
- 1983-09-13 YU YU1846/83A patent/YU43327B/xx unknown
- 1983-09-13 JP JP58167667A patent/JPS5980616A/ja active Granted
- 1983-09-13 AT AT0326383A patent/AT385032B/de not_active IP Right Cessation
- 1983-09-13 AU AU19081/83A patent/AU573535B2/en not_active Expired
- 1983-09-13 IL IL69708A patent/IL69708A/xx not_active IP Right Cessation
- 1983-10-13 FI FI833270A patent/FI83767C/fi not_active IP Right Cessation
-
1986
- 1986-02-24 GB GB08604515A patent/GB2169294B/en not_active Expired
- 1986-06-18 SE SE8602724A patent/SE8602724D0/xx not_active Application Discontinuation
-
1990
- 1990-11-22 HK HK979/90A patent/HK97990A/xx not_active IP Right Cessation
-
1991
- 1991-03-22 CY CY1543A patent/CY1543A/xx unknown
- 1991-09-25 JP JP3315620A patent/JP2759184B2/ja not_active Expired - Lifetime
-
1997
- 1997-09-17 DK DK199701068A patent/DK172732B1/da not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |