IT8322852A0 - Procedimento per la risoluzione di isomeri ottici. - Google Patents
Procedimento per la risoluzione di isomeri ottici.Info
- Publication number
- IT8322852A0 IT8322852A0 IT8322852A IT2285283A IT8322852A0 IT 8322852 A0 IT8322852 A0 IT 8322852A0 IT 8322852 A IT8322852 A IT 8322852A IT 2285283 A IT2285283 A IT 2285283A IT 8322852 A0 IT8322852 A0 IT 8322852A0
- Authority
- IT
- Italy
- Prior art keywords
- resolution
- procedure
- optical isomers
- isomers
- optical
- Prior art date
Links
- 230000003287 optical effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/417,794 US4463176A (en) | 1982-09-13 | 1982-09-13 | Process for resolution of optical isomers |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8322852A0 true IT8322852A0 (it) | 1983-09-12 |
IT1170213B IT1170213B (it) | 1987-06-03 |
Family
ID=23655420
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT22852/83A IT1170213B (it) | 1982-09-13 | 1983-09-12 | Procedimento per la risoluzione di isomeri ottici |
Country Status (29)
Country | Link |
---|---|
US (1) | US4463176A (it) |
JP (2) | JPS5980616A (it) |
KR (1) | KR890000616B1 (it) |
AT (1) | AT385032B (it) |
AU (1) | AU573535B2 (it) |
BE (1) | BE897737A (it) |
CA (1) | CA1250290A (it) |
CH (1) | CH660732A5 (it) |
CY (1) | CY1543A (it) |
DE (1) | DE3333025A1 (it) |
DK (2) | DK172720B1 (it) |
ES (1) | ES525543A0 (it) |
FI (1) | FI83767C (it) |
FR (1) | FR2540490B1 (it) |
GB (2) | GB2127020B (it) |
GR (1) | GR81546B (it) |
HK (1) | HK97990A (it) |
HU (1) | HU193183B (it) |
IE (1) | IE55650B1 (it) |
IL (1) | IL69708A (it) |
IT (1) | IT1170213B (it) |
LU (1) | LU84998A1 (it) |
NL (1) | NL8303154A (it) |
NO (1) | NO159267C (it) |
NZ (1) | NZ205554A (it) |
PT (1) | PT77331B (it) |
SE (2) | SE452608B (it) |
YU (1) | YU43327B (it) |
ZA (1) | ZA836795B (it) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4849527A (en) * | 1982-09-13 | 1989-07-18 | Bristol-Myers Company | Process for resolution of optical isomers |
IT1163107B (it) * | 1983-02-15 | 1987-04-08 | Simes | Composizioni farmaceutiche e loro uso nel trattamento del glaucoma |
US5364872A (en) * | 1984-04-16 | 1994-11-15 | Yamanouchi Pharmaceutical Co., Ltd. | Dihydropyridine-3,5-dicarboxylic acid ester derivatives |
US5039801A (en) * | 1985-12-20 | 1991-08-13 | The United States Of America As Represented By The Department Of Health & Human Services | Thermal fragmentation of methylbenzylurea disastereomers or secondary amines and preparation of optically active secondary amines |
US4797498A (en) * | 1986-07-18 | 1989-01-10 | Pennwalt Corporation | Flavonoxypropanolamines and esters of flavonoxypropanolamines as antiarrhythmic agents |
WO1988007044A1 (en) * | 1987-03-17 | 1988-09-22 | Insite Vision, Inc. | Timolol derivatives |
US4889941A (en) * | 1987-04-23 | 1989-12-26 | Fisons Corporation | Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxygenase |
US4806660A (en) * | 1987-11-06 | 1989-02-21 | Pennwalt Corporation | Aurone oxypropanolamines |
JP2801768B2 (ja) * | 1990-11-17 | 1998-09-21 | 日東電工株式会社 | 新規な光学活性メトプロロール・酒石酸誘導体塩及びその製法、並びにこの塩を用いる光学活性メトプロロールの製法 |
US5082970A (en) * | 1991-03-06 | 1992-01-21 | Pfizer Inc. | Process for recycling amine isomer |
ES2065278B1 (es) * | 1993-06-24 | 1995-09-01 | Medichem Sa | Procedimiento de obtencion enantioselectivo del levobunolol. |
AU702594B2 (en) * | 1995-10-13 | 1999-02-25 | Duphar International Research B.V. | Process for the preparation of enantiomerically pure imidazolyl compounds |
KR100332399B1 (ko) * | 1999-02-22 | 2002-04-13 | 김경호 | 메토프롤롤 라세미체로부터 메토프롤롤 에난티오머의 제조방법 |
BE1012622A3 (fr) * | 1999-04-21 | 2001-01-09 | Solvay | Procede pour la separation d'enantiomeres et reactif enantiopur. |
US7138538B2 (en) * | 2000-04-14 | 2006-11-21 | Solvay (Societe Anonyme) | Process for the separation of enantiomers and enantiopure reagent |
AP2005003232A0 (en) | 2002-08-19 | 2005-03-31 | Pfizer Prod Inc | Combination therapy for hyperproliferative diseases. |
US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
US8404896B2 (en) | 2006-12-01 | 2013-03-26 | Bristol-Myers Squibb Company | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
WO2008112287A1 (en) * | 2007-03-12 | 2008-09-18 | Nektar Therapeutics | Oligomer-beta blocker conjugates |
BR112015026513A2 (pt) | 2013-04-17 | 2017-07-25 | Pfizer | derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
MX2021008533A (es) | 2019-01-18 | 2021-08-19 | Astrazeneca Ab | Inhibidores de la pcsk9 y metodos de uso de los mismos. |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US234595A (en) * | 1880-11-16 | Juan f | ||
GB1211589A (en) * | 1968-08-06 | 1970-11-11 | Ici Ltd | Enantiomer isolation process |
BE786963A (fr) * | 1971-07-30 | 1973-01-29 | Degussa | Procede pour le dedoublement racemique de d,1-phenylpropanolamine |
US4314943A (en) * | 1977-07-13 | 1982-02-09 | Mead Johnson & Company | Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols |
US4234595A (en) * | 1977-07-13 | 1980-11-18 | Mead Johnson & Company | 3-Indolyl-tertiary butylaminopropanols |
IT1113029B (it) * | 1979-03-01 | 1986-01-20 | Simes | Processo per la separazione dei due isomeri ottici del moprololo e composizioni farmaceutiche dell'antipodo levogiro |
JPS5770884A (en) * | 1980-10-21 | 1982-05-01 | Kyowa Hakko Kogyo Co Ltd | Novel piperidine derivative and its preparation |
FI76551C (fi) * | 1980-11-06 | 1988-11-10 | Sandoz Ag | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-aminopropoxifenylderivat. |
-
1982
- 1982-09-13 US US06/417,794 patent/US4463176A/en not_active Expired - Lifetime
-
1983
- 1983-09-12 FR FR8314464A patent/FR2540490B1/fr not_active Expired
- 1983-09-12 ES ES525543A patent/ES525543A0/es active Granted
- 1983-09-12 CA CA000436530A patent/CA1250290A/en not_active Expired
- 1983-09-12 NO NO833254A patent/NO159267C/no not_active IP Right Cessation
- 1983-09-12 NZ NZ205554A patent/NZ205554A/en unknown
- 1983-09-12 BE BE0/211517A patent/BE897737A/fr not_active IP Right Cessation
- 1983-09-12 CH CH4958/83A patent/CH660732A5/fr not_active IP Right Cessation
- 1983-09-12 PT PT77331A patent/PT77331B/pt unknown
- 1983-09-12 IT IT22852/83A patent/IT1170213B/it active
- 1983-09-12 IE IE2134/83A patent/IE55650B1/en not_active IP Right Cessation
- 1983-09-12 SE SE8304887A patent/SE452608B/sv not_active IP Right Cessation
- 1983-09-12 LU LU84998A patent/LU84998A1/fr unknown
- 1983-09-12 GR GR72427A patent/GR81546B/el unknown
- 1983-09-13 JP JP58167667A patent/JPS5980616A/ja active Granted
- 1983-09-13 IL IL69708A patent/IL69708A/xx not_active IP Right Cessation
- 1983-09-13 GB GB08324536A patent/GB2127020B/en not_active Expired
- 1983-09-13 AU AU19081/83A patent/AU573535B2/en not_active Expired
- 1983-09-13 DE DE19833333025 patent/DE3333025A1/de active Granted
- 1983-09-13 NL NL8303154A patent/NL8303154A/nl active Search and Examination
- 1983-09-13 YU YU1846/83A patent/YU43327B/xx unknown
- 1983-09-13 ZA ZA836795A patent/ZA836795B/xx unknown
- 1983-09-13 AT AT0326383A patent/AT385032B/de not_active IP Right Cessation
- 1983-09-13 KR KR1019830004298A patent/KR890000616B1/ko not_active IP Right Cessation
- 1983-09-13 DK DK198304164A patent/DK172720B1/da not_active IP Right Cessation
- 1983-09-13 HU HU833181A patent/HU193183B/hu unknown
- 1983-10-13 FI FI833270A patent/FI83767C/fi not_active IP Right Cessation
-
1986
- 1986-02-24 GB GB08604515A patent/GB2169294B/en not_active Expired
- 1986-06-18 SE SE8602724A patent/SE8602724D0/xx not_active Application Discontinuation
-
1990
- 1990-11-22 HK HK979/90A patent/HK97990A/xx not_active IP Right Cessation
-
1991
- 1991-03-22 CY CY1543A patent/CY1543A/xx unknown
- 1991-09-25 JP JP3315620A patent/JP2759184B2/ja not_active Expired - Lifetime
-
1997
- 1997-09-17 DK DK199701068A patent/DK172732B1/da not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970929 |