IT1216743B - Processo per la preparazioenenzimatica degli isomeri ottici di alcoli primari alfa alchilsostituiti racemi. - Google Patents

Processo per la preparazioenenzimatica degli isomeri ottici di alcoli primari alfa alchilsostituiti racemi.

Info

Publication number
IT1216743B
IT1216743B IT8819361A IT1936188A IT1216743B IT 1216743 B IT1216743 B IT 1216743B IT 8819361 A IT8819361 A IT 8819361A IT 1936188 A IT1936188 A IT 1936188A IT 1216743 B IT1216743 B IT 1216743B
Authority
IT
Italy
Prior art keywords
enzymics
alchyl
racemi
alfa
substituted
Prior art date
Application number
IT8819361A
Other languages
English (en)
Other versions
IT8819361A0 (it
Inventor
Daniele Bianchi
Pietro Cesti
Franco Francalanci
Walter Cabri
Original Assignee
Donegani Guido Ist
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Donegani Guido Ist filed Critical Donegani Guido Ist
Publication of IT8819361A0 publication Critical patent/IT8819361A0/it
Priority to IT8819361A priority Critical patent/IT1216743B/it
Priority to US07/307,913 priority patent/US4980291A/en
Priority to ZA891037A priority patent/ZA891037B/xx
Priority to AU29842/89A priority patent/AU2984289A/en
Priority to IL89232A priority patent/IL89232A0/xx
Priority to KR1019890001648A priority patent/KR890013188A/ko
Priority to BR898900592A priority patent/BR8900592A/pt
Priority to JP1032553A priority patent/JPH01289494A/ja
Priority to EP89102314A priority patent/EP0328125A3/en
Application granted granted Critical
Publication of IT1216743B publication Critical patent/IT1216743B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT8819361A 1988-02-10 1988-02-10 Processo per la preparazioenenzimatica degli isomeri ottici di alcoli primari alfa alchilsostituiti racemi. IT1216743B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT8819361A IT1216743B (it) 1988-02-10 1988-02-10 Processo per la preparazioenenzimatica degli isomeri ottici di alcoli primari alfa alchilsostituiti racemi.
IL89232A IL89232A0 (en) 1988-02-10 1989-02-09 Enzymatic separation of the optical isomers of racemic alpha-alkyl-substituted primary alcohols
ZA891037A ZA891037B (en) 1988-02-10 1989-02-09 Process for the enzymatic separation of the optical isomers of racemic alpha alkyl-substituted primary alcohols
AU29842/89A AU2984289A (en) 1988-02-10 1989-02-09 Process for the enzymatic separation of the optical isomers of racemic alpha-alkyl-substituted primary alcohols
US07/307,913 US4980291A (en) 1988-02-10 1989-02-09 Process for the enzymatic separation of the optical isomers of racemic α-alkyl-substituted primary alcohols
KR1019890001648A KR890013188A (ko) 1988-02-10 1989-02-10 라세믹 α-알킬-치환된 1차알코올의 광학이성체의 효소학적 분리방법
BR898900592A BR8900592A (pt) 1988-02-10 1989-02-10 Processo para separacao biotecnologica e processo para separacao biotecnologica dos isomeros oticos(s)e(r)de alcoois primarios substituidos por-alquila racemicos
JP1032553A JPH01289494A (ja) 1988-02-10 1989-02-10 ラセミα‐アルキル置換一級アルコール類の光学異性体の酵素的分離方法
EP89102314A EP0328125A3 (en) 1988-02-10 1989-02-10 Process for the enzymatic separation of the optical isomers of racemic alpha-alkyl-substituted primary alcohols

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8819361A IT1216743B (it) 1988-02-10 1988-02-10 Processo per la preparazioenenzimatica degli isomeri ottici di alcoli primari alfa alchilsostituiti racemi.

Publications (2)

Publication Number Publication Date
IT8819361A0 IT8819361A0 (it) 1988-02-10
IT1216743B true IT1216743B (it) 1990-03-08

Family

ID=11157041

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8819361A IT1216743B (it) 1988-02-10 1988-02-10 Processo per la preparazioenenzimatica degli isomeri ottici di alcoli primari alfa alchilsostituiti racemi.

Country Status (9)

Country Link
US (1) US4980291A (it)
EP (1) EP0328125A3 (it)
JP (1) JPH01289494A (it)
KR (1) KR890013188A (it)
AU (1) AU2984289A (it)
BR (1) BR8900592A (it)
IL (1) IL89232A0 (it)
IT (1) IT1216743B (it)
ZA (1) ZA891037B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1217765B (it) * 1988-06-02 1990-03-30 Montedison Spa Processo per la risoluzione enzimatica degli isomeri ottici di derivati racemi esterei dell,acido 3 mercapto 2 alchilpropionico
EP0538693A3 (en) * 1991-10-23 1994-08-17 Squibb & Sons Inc Stereoselective preparation of halophenyl alcohols
US5986095A (en) * 1992-01-06 1999-11-16 E.R. Squibb & Sons, Inc. Enantioselective preparation of halophenyl alcohols and acylates
US5324662A (en) * 1992-05-15 1994-06-28 E. R. Squibb & Sons, Inc. Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters
US5420337A (en) * 1992-11-12 1995-05-30 E. R. Squibb & Sons, Inc. Enzymatic reduction method for the preparation of compounds useful for preparing taxanes
AT401385B (de) * 1994-03-30 1996-08-26 Chemie Linz Gmbh Enzymatische racematspaltung asymmetrischer alkohole mittels vinylestern mehrbasiger carbonsäuren
KR0150592B1 (ko) * 1995-01-03 1998-08-17 남창우 효소를 이용한 (r,s)-1,2-페닐에탄디올의 광학적 분할방법
ES2159231B1 (es) * 1999-04-09 2002-05-16 Smithkline Beecham Sa Procedimiento de resolucion de mezclas enantiomericas de alcoholes catalizada por lipasas.
KR100341255B1 (ko) * 1999-09-11 2002-06-21 박호군 4급 비대칭탄소를 함유하는 라세미체 알콜 화합물의 분할방법과 시스탄 유사체의 합성
KR100341256B1 (ko) * 1999-09-11 2002-06-21 박호군 리파제를 이용한 베라파밀 중간체의 분할 및 (ｒ)- 및 (ｓ)-베라파밀의 제조 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0740956B2 (ja) * 1986-01-21 1995-05-10 チッソ株式会社 生化学的手法による光学活性なアルコ−ルの製造法
IT1198266B (it) * 1986-12-30 1988-12-21 Montedison Spa Processo per la separazione enzimatica degli isomeri ottici di derivati ossazolidinonici racemi

Also Published As

Publication number Publication date
JPH01289494A (ja) 1989-11-21
AU2984289A (en) 1989-08-10
ZA891037B (en) 1989-10-25
EP0328125A3 (en) 1990-07-18
EP0328125A2 (en) 1989-08-16
IT8819361A0 (it) 1988-02-10
BR8900592A (pt) 1989-10-10
IL89232A0 (en) 1989-09-10
US4980291A (en) 1990-12-25
KR890013188A (ko) 1989-09-21

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