SE461590B - Derivat av 6-hexahydronaftyletyl-4-hydroxi-tetrahydropyren-2-on, foerfarande foer framstaellning av dessa och en farmaceutisk komposition till anvaendning foer haemning av kolesterol - Google Patents

Derivat av 6-hexahydronaftyletyl-4-hydroxi-tetrahydropyren-2-on, foerfarande foer framstaellning av dessa och en farmaceutisk komposition till anvaendning foer haemning av kolesterol

Info

Publication number
SE461590B
SE461590B SE8102047A SE8102047A SE461590B SE 461590 B SE461590 B SE 461590B SE 8102047 A SE8102047 A SE 8102047A SE 8102047 A SE8102047 A SE 8102047A SE 461590 B SE461590 B SE 461590B
Authority
SE
Sweden
Prior art keywords
group
straight
carbon atoms
branched chain
hydrogen atom
Prior art date
Application number
SE8102047A
Other languages
English (en)
Swedish (sv)
Other versions
SE8102047L (sv
Inventor
A Sato
A Terahara
Y Tsujita
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12604367&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE461590(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of SE8102047L publication Critical patent/SE8102047L/
Publication of SE461590B publication Critical patent/SE461590B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SE8102047A 1980-03-31 1981-03-31 Derivat av 6-hexahydronaftyletyl-4-hydroxi-tetrahydropyren-2-on, foerfarande foer framstaellning av dessa och en farmaceutisk komposition till anvaendning foer haemning av kolesterol SE461590B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55041292A JPH0692381B2 (ja) 1980-03-31 1980-03-31 Ｍｂ−５３０ａ誘導体

Publications (2)

Publication Number Publication Date
SE8102047L SE8102047L (sv) 1981-10-01
SE461590B true SE461590B (sv) 1990-03-05

Family

ID=12604367

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8102047A SE461590B (sv) 1980-03-31 1981-03-31 Derivat av 6-hexahydronaftyletyl-4-hydroxi-tetrahydropyren-2-on, foerfarande foer framstaellning av dessa och en farmaceutisk komposition till anvaendning foer haemning av kolesterol

Country Status (15)

Country Link
JP (1) JPH0692381B2 (OSRAM)
AT (1) ATA150781A (OSRAM)
AU (1) AU6893281A (OSRAM)
BE (1) BE888214A (OSRAM)
CH (1) CH646966A5 (OSRAM)
DE (2) DE3112566A1 (OSRAM)
DK (3) DK151273C (OSRAM)
FI (1) FI810991A7 (OSRAM)
FR (1) FR2479222A1 (OSRAM)
GB (1) GB2073193A (OSRAM)
IE (1) IE52367B1 (OSRAM)
IT (1) IT1144325B (OSRAM)
MX (1) MX9203567A (OSRAM)
NL (1) NL8101592A (OSRAM)
SE (1) SE461590B (OSRAM)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472426A (en) * 1982-12-22 1984-09-18 Merck & Co., Inc. Antihypercholesterolemic compounds
ATE69602T1 (de) * 1985-09-13 1991-12-15 Sankyo Co Hydroxy-ml-236b-derivate, deren herstellung und anwendung.
US4997848A (en) * 1987-10-27 1991-03-05 Sankyo Company, Limited Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition
US5075327A (en) * 1988-08-10 1991-12-24 Hoffmann-La Roche Inc. Antipsoriatic agents
US5021451A (en) * 1988-11-14 1991-06-04 Hoffman-La Roche Inc. Method for inhibiting hyperproliferative diseases
US5073568A (en) * 1988-11-14 1991-12-17 Hoffmann-La Roche Inc. Antipsoriatic agents
US5200549A (en) * 1988-11-14 1993-04-06 Hoffman-La Roche Inc. Antipsoriatic agents
US5159104A (en) * 1991-05-01 1992-10-27 Merck & Co., Inc. Process to simvastatin ester
FR2937537A1 (fr) * 2008-10-29 2010-04-30 Centre Nat Rech Scient Nanoparticules de statine
KR101820099B1 (ko) 2013-01-18 2018-01-18 에스프린팅솔루션 주식회사 저항 발열체, 이를 채용한 가열 부재, 및 정착 장치
CN111788196A (zh) * 2018-01-09 2020-10-16 配体药物公司 缩醛化合物及其治疗用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5612114B2 (OSRAM) * 1974-06-07 1981-03-18
JPS5925599B2 (ja) * 1979-02-20 1984-06-19 三共株式会社 新生理活性物質モナコリンｋおよびその製造法
IL60219A (en) * 1979-06-15 1985-05-31 Merck & Co Inc Hypocholesteremic fermentation products of the hmg-coa reductase inhibitor type,their preparation and pharmaceutical compositions containing them
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
US4282155A (en) * 1980-02-04 1981-08-04 Merck & Co., Inc. Antihypercholesterolemic compounds
ZA81703B (en) * 1980-02-04 1982-09-29 Merck & Co Inc New antihypercholesterolemic compounds,intermediates and processes
AU548996B2 (en) * 1980-02-04 1986-01-09 Merck & Co., Inc. Tetrahydro-2h-pyran-2-one derivatives
PT72394B (en) * 1980-02-04 1982-09-06 Merck & Co Inc Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics

Also Published As

Publication number Publication date
SE8102047L (sv) 1981-10-01
MX9203567A (es) 1992-09-01
DK32190D0 (da) 1990-02-07
JPS56138181A (en) 1981-10-28
IE810698L (en) 1981-09-30
DK32290A (da) 1990-02-07
DE3112566C2 (OSRAM) 1990-04-05
FI810991L (fi) 1981-10-01
DK32290D0 (da) 1990-02-07
DK151273C (da) 1988-07-04
CH646966A5 (de) 1984-12-28
AU6893281A (en) 1981-10-08
DK145481A (da) 1981-10-01
FI810991A7 (fi) 1981-10-01
IT1144325B (it) 1986-10-29
DE3112566A1 (de) 1982-03-11
FR2479222B1 (OSRAM) 1983-08-26
IE52367B1 (en) 1987-09-30
IT8167438A0 (it) 1981-03-30
ATA150781A (de) 1983-03-15
FR2479222A1 (fr) 1981-10-02
NL8101592A (nl) 1981-10-16
DK151273B (da) 1987-11-16
JPH0692381B2 (ja) 1994-11-16
BE888214A (fr) 1981-09-30
DK32190A (da) 1990-02-07
DK167805B1 (da) 1993-12-20
DE3153666C2 (de) 1993-11-11
GB2073193A (en) 1981-10-14

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