DK32190D0 - Mellemprodukt til fremstilling af cholesterolsynteseinhibitorer og fremgangsmaade til fremstilling af mellemproduktet - Google Patents

Mellemprodukt til fremstilling af cholesterolsynteseinhibitorer og fremgangsmaade til fremstilling af mellemproduktet

Info

Publication number
DK32190D0
DK32190D0 DK032190A DK32190A DK32190D0 DK 32190 D0 DK32190 D0 DK 32190D0 DK 032190 A DK032190 A DK 032190A DK 32190 A DK32190 A DK 32190A DK 32190 D0 DK32190 D0 DK 32190D0
Authority
DK
Denmark
Prior art keywords
procedure
preparation
production
synthesis inhibitors
cholesterol synthesis
Prior art date
Application number
DK032190A
Other languages
English (en)
Other versions
DK167805B1 (da
DK32190A (da
Inventor
Aiya Sato
Akira Terahara
Yoshio Tsujita
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12604367&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK32190(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of DK32190D0 publication Critical patent/DK32190D0/da
Publication of DK32190A publication Critical patent/DK32190A/da
Application granted granted Critical
Publication of DK167805B1 publication Critical patent/DK167805B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/06Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK032190A 1980-03-31 1990-02-07 Mellemprodukt til fremstilling af cholesterolsynteseinhibitorer DK167805B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55041292A JPH0692381B2 (ja) 1980-03-31 1980-03-31 Mb−530a誘導体
JP4129280 1980-03-31

Publications (3)

Publication Number Publication Date
DK32190D0 true DK32190D0 (da) 1990-02-07
DK32190A DK32190A (da) 1990-02-07
DK167805B1 DK167805B1 (da) 1993-12-20

Family

ID=12604367

Family Applications (3)

Application Number Title Priority Date Filing Date
DK145481A DK151273C (da) 1980-03-31 1981-03-31 Fremgangsmaade til fremstilling af cholesterolbiosynteseinhibitoren mb- 530a.
DK032290A DK32290A (da) 1980-03-31 1990-02-07 Anvendelse af 8'-acylerede derivater af mellemproduktforbindelsen mb-530a til fremstilling af et laegemiddel til behandling af hypercholesterolaemi
DK032190A DK167805B1 (da) 1980-03-31 1990-02-07 Mellemprodukt til fremstilling af cholesterolsynteseinhibitorer

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK145481A DK151273C (da) 1980-03-31 1981-03-31 Fremgangsmaade til fremstilling af cholesterolbiosynteseinhibitoren mb- 530a.
DK032290A DK32290A (da) 1980-03-31 1990-02-07 Anvendelse af 8'-acylerede derivater af mellemproduktforbindelsen mb-530a til fremstilling af et laegemiddel til behandling af hypercholesterolaemi

Country Status (15)

Country Link
JP (1) JPH0692381B2 (da)
AT (1) ATA150781A (da)
AU (1) AU6893281A (da)
BE (1) BE888214A (da)
CH (1) CH646966A5 (da)
DE (2) DE3112566A1 (da)
DK (3) DK151273C (da)
FI (1) FI810991L (da)
FR (1) FR2479222A1 (da)
GB (1) GB2073193A (da)
IE (1) IE52367B1 (da)
IT (1) IT1144325B (da)
MX (1) MX9203567A (da)
NL (1) NL8101592A (da)
SE (1) SE461590B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472426A (en) * 1982-12-22 1984-09-18 Merck & Co., Inc. Antihypercholesterolemic compounds
DE3682557D1 (de) * 1985-09-13 1992-01-02 Sankyo Co Hydroxy-ml-236b-derivate, deren herstellung und anwendung.
US4997848A (en) * 1987-10-27 1991-03-05 Sankyo Company, Limited Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition
US5075327A (en) * 1988-08-10 1991-12-24 Hoffmann-La Roche Inc. Antipsoriatic agents
US5021451A (en) * 1988-11-14 1991-06-04 Hoffman-La Roche Inc. Method for inhibiting hyperproliferative diseases
US5200549A (en) * 1988-11-14 1993-04-06 Hoffman-La Roche Inc. Antipsoriatic agents
US5073568A (en) * 1988-11-14 1991-12-17 Hoffmann-La Roche Inc. Antipsoriatic agents
US5159104A (en) * 1991-05-01 1992-10-27 Merck & Co., Inc. Process to simvastatin ester
FR2937537A1 (fr) * 2008-10-29 2010-04-30 Centre Nat Rech Scient Nanoparticules de statine
KR101820099B1 (ko) 2013-01-18 2018-01-18 에스프린팅솔루션 주식회사 저항 발열체, 이를 채용한 가열 부재, 및 정착 장치
RU2020126177A (ru) 2018-01-09 2022-02-10 Лиганд Фармасьютикалз, Инк. Ацетальные соединения и их терапевтическое применение

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5612114B2 (da) * 1974-06-07 1981-03-18
JPS5925599B2 (ja) * 1979-02-20 1984-06-19 三共株式会社 新生理活性物質モナコリンkおよびその製造法
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
AU535944B2 (en) * 1979-06-15 1984-04-12 Merck & Co., Inc. Hypocholestermic fermentation products from aspergillus
PT72394B (en) * 1980-02-04 1982-09-06 Merck & Co Inc Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics
US4282155A (en) * 1980-02-04 1981-08-04 Merck & Co., Inc. Antihypercholesterolemic compounds
AU548996B2 (en) * 1980-02-04 1986-01-09 Merck & Co., Inc. Tetrahydro-2h-pyran-2-one derivatives
ZA81703B (en) * 1980-02-04 1982-09-29 Merck & Co Inc New antihypercholesterolemic compounds,intermediates and processes

Also Published As

Publication number Publication date
AU6893281A (en) 1981-10-08
SE8102047L (sv) 1981-10-01
DK145481A (da) 1981-10-01
DE3112566A1 (de) 1982-03-11
IT1144325B (it) 1986-10-29
BE888214A (fr) 1981-09-30
ATA150781A (de) 1983-03-15
DK32290D0 (da) 1990-02-07
DK32290A (da) 1990-02-07
DK167805B1 (da) 1993-12-20
FR2479222B1 (da) 1983-08-26
MX9203567A (es) 1992-09-01
GB2073193A (en) 1981-10-14
JPS56138181A (en) 1981-10-28
FR2479222A1 (fr) 1981-10-02
CH646966A5 (de) 1984-12-28
DK32190A (da) 1990-02-07
SE461590B (sv) 1990-03-05
DK151273C (da) 1988-07-04
IT8167438A0 (it) 1981-03-30
IE810698L (en) 1981-09-30
DE3153666C2 (de) 1993-11-11
DK151273B (da) 1987-11-16
FI810991L (fi) 1981-10-01
JPH0692381B2 (ja) 1994-11-16
DE3112566C2 (da) 1990-04-05
NL8101592A (nl) 1981-10-16
IE52367B1 (en) 1987-09-30

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired