DK32190A - Mellemprodukt til fremstilling af cholesterolsynteseinhibitorer og fremgangsmaade til fremstilling af mellemproduktet - Google Patents
Mellemprodukt til fremstilling af cholesterolsynteseinhibitorer og fremgangsmaade til fremstilling af mellemproduktet Download PDFInfo
- Publication number
- DK32190A DK32190A DK032190A DK32190A DK32190A DK 32190 A DK32190 A DK 32190A DK 032190 A DK032190 A DK 032190A DK 32190 A DK32190 A DK 32190A DK 32190 A DK32190 A DK 32190A
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- preparation
- production
- synthesis inhibitors
- cholesterol synthesis
- Prior art date
Links
- 229940127328 Cholesterol Synthesis Inhibitors Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4129280 | 1980-03-31 | ||
JP55041292A JPH0692381B2 (ja) | 1980-03-31 | 1980-03-31 | Mb−530a誘導体 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK32190A true DK32190A (da) | 1990-02-07 |
DK32190D0 DK32190D0 (da) | 1990-02-07 |
DK167805B1 DK167805B1 (da) | 1993-12-20 |
Family
ID=12604367
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK145481A DK151273C (da) | 1980-03-31 | 1981-03-31 | Fremgangsmaade til fremstilling af cholesterolbiosynteseinhibitoren mb- 530a. |
DK032290A DK32290A (da) | 1980-03-31 | 1990-02-07 | Anvendelse af 8'-acylerede derivater af mellemproduktforbindelsen mb-530a til fremstilling af et laegemiddel til behandling af hypercholesterolaemi |
DK032190A DK167805B1 (da) | 1980-03-31 | 1990-02-07 | Mellemprodukt til fremstilling af cholesterolsynteseinhibitorer |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK145481A DK151273C (da) | 1980-03-31 | 1981-03-31 | Fremgangsmaade til fremstilling af cholesterolbiosynteseinhibitoren mb- 530a. |
DK032290A DK32290A (da) | 1980-03-31 | 1990-02-07 | Anvendelse af 8'-acylerede derivater af mellemproduktforbindelsen mb-530a til fremstilling af et laegemiddel til behandling af hypercholesterolaemi |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPH0692381B2 (da) |
AT (1) | ATA150781A (da) |
AU (1) | AU6893281A (da) |
BE (1) | BE888214A (da) |
CH (1) | CH646966A5 (da) |
DE (2) | DE3112566A1 (da) |
DK (3) | DK151273C (da) |
FI (1) | FI810991L (da) |
FR (1) | FR2479222A1 (da) |
GB (1) | GB2073193A (da) |
IE (1) | IE52367B1 (da) |
IT (1) | IT1144325B (da) |
MX (1) | MX9203567A (da) |
NL (1) | NL8101592A (da) |
SE (1) | SE461590B (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4472426A (en) * | 1982-12-22 | 1984-09-18 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
DE3682557D1 (de) * | 1985-09-13 | 1992-01-02 | Sankyo Co | Hydroxy-ml-236b-derivate, deren herstellung und anwendung. |
US4997848A (en) * | 1987-10-27 | 1991-03-05 | Sankyo Company, Limited | Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition |
US5075327A (en) * | 1988-08-10 | 1991-12-24 | Hoffmann-La Roche Inc. | Antipsoriatic agents |
US5021451A (en) * | 1988-11-14 | 1991-06-04 | Hoffman-La Roche Inc. | Method for inhibiting hyperproliferative diseases |
US5200549A (en) * | 1988-11-14 | 1993-04-06 | Hoffman-La Roche Inc. | Antipsoriatic agents |
US5073568A (en) * | 1988-11-14 | 1991-12-17 | Hoffmann-La Roche Inc. | Antipsoriatic agents |
US5159104A (en) * | 1991-05-01 | 1992-10-27 | Merck & Co., Inc. | Process to simvastatin ester |
FR2937537A1 (fr) * | 2008-10-29 | 2010-04-30 | Centre Nat Rech Scient | Nanoparticules de statine |
KR101820099B1 (ko) | 2013-01-18 | 2018-01-18 | 에스프린팅솔루션 주식회사 | 저항 발열체, 이를 채용한 가열 부재, 및 정착 장치 |
AU2019207625A1 (en) | 2018-01-09 | 2020-07-30 | Ligand Pharmaceuticals, Inc. | Acetal compounds and therapeutic uses thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5612114B2 (da) * | 1974-06-07 | 1981-03-18 | ||
JPS5925599B2 (ja) * | 1979-02-20 | 1984-06-19 | 三共株式会社 | 新生理活性物質モナコリンkおよびその製造法 |
US4231938A (en) * | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
AU535944B2 (en) * | 1979-06-15 | 1984-04-12 | Merck & Co., Inc. | Hypocholestermic fermentation products from aspergillus |
PT72394B (en) * | 1980-02-04 | 1982-09-06 | Merck & Co Inc | Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics |
AU548996B2 (en) * | 1980-02-04 | 1986-01-09 | Merck & Co., Inc. | Tetrahydro-2h-pyran-2-one derivatives |
ZA81703B (en) * | 1980-02-04 | 1982-09-29 | Merck & Co Inc | New antihypercholesterolemic compounds,intermediates and processes |
US4282155A (en) * | 1980-02-04 | 1981-08-04 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
-
1980
- 1980-03-31 JP JP55041292A patent/JPH0692381B2/ja not_active Expired - Lifetime
-
1981
- 1981-03-27 IE IE698/81A patent/IE52367B1/en not_active IP Right Cessation
- 1981-03-30 IT IT67438/81A patent/IT1144325B/it active
- 1981-03-30 CH CH215381A patent/CH646966A5/de not_active IP Right Cessation
- 1981-03-30 DE DE19813112566 patent/DE3112566A1/de active Granted
- 1981-03-30 DE DE3153666A patent/DE3153666C2/de not_active Expired - Lifetime
- 1981-03-31 GB GB8110075A patent/GB2073193A/en not_active Withdrawn
- 1981-03-31 FI FI810991A patent/FI810991L/fi not_active Application Discontinuation
- 1981-03-31 AT AT0150781A patent/ATA150781A/de not_active IP Right Cessation
- 1981-03-31 DK DK145481A patent/DK151273C/da not_active IP Right Cessation
- 1981-03-31 NL NL8101592A patent/NL8101592A/nl not_active Application Discontinuation
- 1981-03-31 FR FR8106403A patent/FR2479222A1/fr active Granted
- 1981-03-31 SE SE8102047A patent/SE461590B/sv not_active Application Discontinuation
- 1981-03-31 AU AU68932/81A patent/AU6893281A/en not_active Abandoned
- 1981-03-31 BE BE0/204328A patent/BE888214A/fr not_active IP Right Cessation
-
1990
- 1990-02-07 DK DK032290A patent/DK32290A/da not_active Application Discontinuation
- 1990-02-07 DK DK032190A patent/DK167805B1/da not_active IP Right Cessation
-
1992
- 1992-06-26 MX MX9203567A patent/MX9203567A/es unknown
Also Published As
Publication number | Publication date |
---|---|
MX9203567A (es) | 1992-09-01 |
DK32290D0 (da) | 1990-02-07 |
DK151273C (da) | 1988-07-04 |
DK32290A (da) | 1990-02-07 |
IT1144325B (it) | 1986-10-29 |
JPH0692381B2 (ja) | 1994-11-16 |
IT8167438A0 (it) | 1981-03-30 |
SE8102047L (sv) | 1981-10-01 |
FI810991L (fi) | 1981-10-01 |
DE3112566A1 (de) | 1982-03-11 |
SE461590B (sv) | 1990-03-05 |
CH646966A5 (de) | 1984-12-28 |
DE3153666C2 (de) | 1993-11-11 |
FR2479222A1 (fr) | 1981-10-02 |
IE52367B1 (en) | 1987-09-30 |
DK32190D0 (da) | 1990-02-07 |
DK145481A (da) | 1981-10-01 |
DK151273B (da) | 1987-11-16 |
DE3112566C2 (da) | 1990-04-05 |
IE810698L (en) | 1981-09-30 |
DK167805B1 (da) | 1993-12-20 |
BE888214A (fr) | 1981-09-30 |
GB2073193A (en) | 1981-10-14 |
ATA150781A (de) | 1983-03-15 |
NL8101592A (nl) | 1981-10-16 |
JPS56138181A (en) | 1981-10-28 |
FR2479222B1 (da) | 1983-08-26 |
AU6893281A (en) | 1981-10-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PUP | Patent expired |